Lista de obras - Andrei Leitao - Dominio Público Uruguay

A combined study using ligand-based design, synthesis, and pharmacological evaluation of analogues of the acetaminophen ortho-regioisomer with potent analgesic activity

artículo científico publicado en 2012

A comparative study of warheads for design of cysteine protease inhibitors

artículo científico publicado en 2017

Anti-trypanosomal activity of non-peptidic nitrile-based cysteine protease inhibitors

artículo científico publicado en 2017

Apoferritin encapsulation of cysteine protease inhibitors for cathepsin L inhibition in cancer cells

artículo científico publicado en 2019

Biological Activity and Physicochemical Properties of Dipeptidyl Nitrile Derivatives Against Pancreatic Ductal Adenocarcinoma Cells

artículo científico publicado en 2019

Can Cysteine Protease Cross-Class Inhibitors Achieve Selectivity?

scientific article published on 15 August 2019

Characterization, solubility and biological activity of amphihilic biopolymeric Schiff bases synthesized using chitosans

artículo científico publicado en 2019

Chitosan-laponite nanocomposite scaffolds for wound dressing application

artículo científico publicado en 2019

Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system

artículo científico publicado en 2009

Dipeptidyl nitrile derivatives have cytostatic effects against Leishmania spp. promastigotes

artículo científico publicado en 2019

Discovery of small molecule inhibitors of Leishmania braziliensis Hsp90 chaperone

artículo científico publicado en 2020

Efficient calculation of molecular properties from simulation using kernel molecular dynamics.

artículo científico publicado en 2008

Evaluating QM/MM Free Energy Surfaces for Ranking Cysteine Protease Covalent Inhibitors

artículo científico publicado en 2020

Experimental study and computational modelling of cruzain cysteine protease inhibition by dipeptidyl nitriles

scientific article published on 01 September 2018

In silico screening of HIV-1 non-nucleoside reverse transcriptase and protease inhibitors

artículo científico publicado en 2007

In silico selection and cell-based characterization of selective and bioactive compounds for androgen-dependent prostate cancer cell.

artículo científico publicado en 2016

In vivo effects of a GPR30 antagonist

artículo científico publicado en 2009

Integration of methods in cheminformatics and biocalorimetry for the design of trypanosomatid enzyme inhibitors.

artículo científico publicado en 2014

Leveraging the cruzain S3 subsite to increase affinity for reversible covalent inhibitors

artículo científico publicado en 2018

Ligand efficiency metrics considered harmful

artículo científico publicado en 2014

Ligand-induced conformational selection predicts the selectivity of cysteine protease inhibitors

artículo científico publicado en 2019

Mapping the S1 and S1' subsites of cysteine proteases with new dipeptidyl nitrile inhibitors as trypanocidal agents

artículo científico publicado en 2020

Molecular Design, Synthesis and Trypanocidal Activity of Dipeptidyl Nitriles as Cruzain Inhibitors

artículo científico publicado en 2015

Molecular design, synthesis and biological evaluation of 1,4-dihydro-4-oxoquinoline ribonucleosides as TcGAPDH inhibitors with trypanocidal activity.

artículo científico publicado en 2013

Novel anti-prostate cancer scaffold identified by the combination of in silico and cell-based assays targeting the PI3K-AKT-mTOR pathway.

artículo científico publicado en 2017

Novel derivatives of 1,3,4-oxadiazoles are potent mitostatic agents featuring strong microtubule depolymerizing activity in the sea urchin embryo and cell culture assays

artículo científico publicado en 2010

On the use of porous nanomaterials to photoinactivate E . coli with natural sunlight irradiation

scholarly article by Renan C.F. Leitao et al published December 2015 in Solar Energy

Organometallic Gold(III) Complex [Au(Hdamp)(L14)]+ (L1 = SNS-Donating Thiosemicarbazone) as a Candidate to New Formulations against Chagas Disease

artículo científico publicado en 2019

Photolysis of parabens using medium-pressure mercury lamps: Toxicity effects in MCF7, Balb/c 3T3 cells and Ceriodaphnia dubia

artículo científico publicado en 2018

Predicting the affinity of halogenated reversible covalent inhibitors through relative binding free energy

scientific article published on 04 November 2019

Small molecule inhibitors of hantavirus infection

artículo científico publicado en 2010

Structure-activity relationships of novel inhibitors of glyceraldehyde-3-phosphate dehydrogenase.

artículo científico publicado en 2004

Synthesis and structure-activity relationship of nitrile-based cruzain inhibitors incorporating a trifluoroethylamine-based P2 amide replacement

scientific article published on 28 August 2019

Targeting the Shc-EGFR interaction with indomethacin inhibits MAP kinase pathway signalling

artículo científico publicado en 2019

The molecular retention mechanism in reversed-phase liquid chromatography of meso-ionic compounds by quantitative structure-retention relationships (QSRR)

artículo científico publicado en 2005

The role of molecular interaction fields on enantioselective and nonselective separation of chiral sulfoxides

artículo científico publicado en 2006

Three-dimensional models of non-steroidal ligands: a comparative molecular field analysis.

artículo científico publicado en 2006

Understanding virulence mechanisms in M. tuberculosis infection via A circuit-based simulation framework

artículo científico publicado en 2008

Lista de obras de Andrei Leitao

A combined study using ligand-based design, synthesis, and pharmacological evaluation of analogues of the acetaminophen ortho-regioisomer with potent analgesic activity

A comparative study of warheads for design of cysteine protease inhibitors

Anti-trypanosomal activity of non-peptidic nitrile-based cysteine protease inhibitors

Apoferritin encapsulation of cysteine protease inhibitors for cathepsin L inhibition in cancer cells

Biological Activity and Physicochemical Properties of Dipeptidyl Nitrile Derivatives Against Pancreatic Ductal Adenocarcinoma Cells

Can Cysteine Protease Cross-Class Inhibitors Achieve Selectivity?

Characterization, solubility and biological activity of amphihilic biopolymeric Schiff bases synthesized using chitosans

Chitosan-laponite nanocomposite scaffolds for wound dressing application

Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system

Dipeptidyl nitrile derivatives have cytostatic effects against Leishmania spp. promastigotes

Discovery of small molecule inhibitors of Leishmania braziliensis Hsp90 chaperone

Efficient calculation of molecular properties from simulation using kernel molecular dynamics.

Evaluating QM/MM Free Energy Surfaces for Ranking Cysteine Protease Covalent Inhibitors

Experimental study and computational modelling of cruzain cysteine protease inhibition by dipeptidyl nitriles

In silico screening of HIV-1 non-nucleoside reverse transcriptase and protease inhibitors

In silico selection and cell-based characterization of selective and bioactive compounds for androgen-dependent prostate cancer cell.

In vivo effects of a GPR30 antagonist

Integration of methods in cheminformatics and biocalorimetry for the design of trypanosomatid enzyme inhibitors.

Leveraging the cruzain S3 subsite to increase affinity for reversible covalent inhibitors

Ligand efficiency metrics considered harmful

Ligand-induced conformational selection predicts the selectivity of cysteine protease inhibitors

Mapping the S1 and S1' subsites of cysteine proteases with new dipeptidyl nitrile inhibitors as trypanocidal agents

Molecular Design, Synthesis and Trypanocidal Activity of Dipeptidyl Nitriles as Cruzain Inhibitors

Molecular design, synthesis and biological evaluation of 1,4-dihydro-4-oxoquinoline ribonucleosides as TcGAPDH inhibitors with trypanocidal activity.

Novel anti-prostate cancer scaffold identified by the combination of in silico and cell-based assays targeting the PI3K-AKT-mTOR pathway.

Novel derivatives of 1,3,4-oxadiazoles are potent mitostatic agents featuring strong microtubule depolymerizing activity in the sea urchin embryo and cell culture assays

On the use of porous nanomaterials to photoinactivate E . coli with natural sunlight irradiation

Organometallic Gold(III) Complex [Au(Hdamp)(L14)]+ (L1 = SNS-Donating Thiosemicarbazone) as a Candidate to New Formulations against Chagas Disease

Photolysis of parabens using medium-pressure mercury lamps: Toxicity effects in MCF7, Balb/c 3T3 cells and Ceriodaphnia dubia

Predicting the affinity of halogenated reversible covalent inhibitors through relative binding free energy

Small molecule inhibitors of hantavirus infection

Structure-activity relationships of novel inhibitors of glyceraldehyde-3-phosphate dehydrogenase.

Synthesis and structure-activity relationship of nitrile-based cruzain inhibitors incorporating a trifluoroethylamine-based P2 amide replacement

Targeting the Shc-EGFR interaction with indomethacin inhibits MAP kinase pathway signalling

The molecular retention mechanism in reversed-phase liquid chromatography of meso-ionic compounds by quantitative structure-retention relationships (QSRR)

The role of molecular interaction fields on enantioselective and nonselective separation of chiral sulfoxides

Three-dimensional models of non-steroidal ligands: a comparative molecular field analysis.

Understanding virulence mechanisms in M. tuberculosis infection via A circuit-based simulation framework