Filtros de búsqueda

Lista de obras de Marcus Bantscheff

A Bayesian semi-parametric model for thermal proteome profiling

scientific article published on 29 June 2021

A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles

artículo científico publicado en 2020

A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation

artículo científico publicado en 2012

Affinity profiling of the cellular kinome for the nucleotide cofactors ATP, ADP, and GTP.

artículo científico publicado en 2013

Biological plasticity rescues target activity in CRISPR knock outs

scientific article published on 28 October 2019

CDK12 inhibition reduces abnormalities in cells from patients with myotonic dystrophy and in a mouse model

artículo científico publicado en 2020

Ca

artículo científico publicado en 2021

Chemical and pathway proteomics: powerful tools for oncology drug discovery and personalized health care.

artículo científico publicado en 2008

Chemical proteomic analysis reveals the drugability of the kinome of Trypanosoma brucei.

artículo científico publicado en 2012

Chemical proteomics reveals target selectivity of clinical Jak inhibitors in human primary cells

scientific article published on 02 October 2019

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

artículo científico publicado en 2011

Chemoproteomics reveals time-dependent binding of histone deacetylase inhibitors to endogenous repressor complexes

artículo científico publicado en 2014

Confident phosphorylation site localization using the Mascot Delta Score

artículo científico publicado en 2010

Differential Kinobeads Profiling for Target Identification of Irreversible Kinase Inhibitors.

artículo científico publicado en 2017

Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor

artículo científico publicado en 2019

Discovery of a Highly Selective Tankyrase Inhibitor Displaying Growth Inhibition Effects against a Diverse Range of Tumor Derived Cell Lines.

artículo científico publicado en 2017

Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia

artículo científico publicado en 2021

Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2

artículo científico publicado en 2020

Human Proteinpedia enables sharing of human protein data

artículo científico publicado en 2008

Identification of KasA as the cellular target of an anti-tubercular scaffold

artículo científico publicado en 2016

Identifying drug targets in tissues and whole blood with thermal-shift profiling

scientific article published on 20 January 2020

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

artículo científico publicado en 2011

Mass-spectrometry-based draft of the Arabidopsis proteome

scientific article published on 11 March 2020

Mass-spectrometry-based draft of the human proteome

artículo científico publicado en 2014

Measuring and managing ratio compression for accurate iTRAQ/TMT quantification

artículo científico publicado en 2013

Meltome atlas-thermal proteome stability across the tree of life

scientific article published on 13 April 2020

Monitoring Cell-surface N-Glycoproteome Dynamics by Quantitative Proteomics Reveals Mechanistic Insights into Macrophage Differentiation.

artículo científico publicado en 2017

Nonparametric Analysis of Thermal Proteome Profiles Reveals Novel Drug-binding Proteins

scientific article published on 03 October 2019

Optimization of Orally Bioavailable PI3Kδ Inhibitors and Identification of Vps34 as a Key Selectivity Target

scientific article published on 08 January 2020

PROTAC-Mediated Degradation of Bruton's Tyrosine Kinase Is Inhibited by Covalent Binding

scientific article published on 27 February 2019

Pathway proteomics and chemical proteomics team up in drug discovery.

artículo científico publicado en 2007

Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition

artículo científico publicado en 2016

Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP

artículo científico publicado en 2019

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

artículo científico publicado en 2007

Selective targeting of BD1 and BD2 of the BET proteins in cancer and immuno-inflammation

artículo científico publicado en 2020

Selectively Targeting the Kinome-Conserved Lysine of PI3Kδ as a General Approach to Covalent Kinase Inhibition

artículo científico publicado en 2017

Systematic analysis of protein turnover in primary cells.

artículo científico publicado en 2018

The commonly used PI3-kinase probe LY294002 is an inhibitor of BET bromodomains

artículo científico publicado en 2014

Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat.

artículo científico publicado en 2016

Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry.

artículo científico publicado en 2015

Thermal proteome profiling monitors ligand interactions with cellular membrane proteins.

artículo científico publicado en 2015

Tracking cancer drugs in living cells by thermal profiling of the proteome

artículo científico publicado en 2014

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda