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Lista de obras de Yang-Xin Fu

A STING-activating nanovaccine for cancer immunotherapy

artículo científico publicado en 2017

A bioactive mammalian disaccharide associated with autoimmunity activates STING-TBK1-dependent immune response.

artículo científico publicado en 2019

A dendritic-cell-stromal axis maintains immune responses in lymph nodes

artículo científico publicado en 2015

A mouse model for HBV immunotolerance and immunotherapy.

artículo científico publicado en 2013

A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8+ T-cell response and effective tumor control

scientific article published on 28 August 2019

A novel dendritic cell targeting HPV16 E7 synthetic vaccine in combination with PD-L1 blockade elicits therapeutic antitumor immunity in mice.

artículo científico publicado en 2016

A novel method for synthetic vaccine construction based on protein assembly

artículo científico publicado en 2014

A role for lymphotoxin in the acquisition of Ly49 receptors during NK cell development.

artículo científico publicado en 2004

Active immunotherapy combined with blockade of a coinhibitory pathway achieves regression of large tumor masses in cancer-prone mice

artículo científico

Adapting conventional cancer treatment for immunotherapy

artículo científico publicado en 2016

Adaptive immune cells temper initial innate responses

artículo científico publicado en 2007

Adenovirally delivered IFN-β exerts antitumor effects through transient T-lymphocyte depletion and Ag-specific T-cell proliferation

artículo científico

Androgen receptor antagonists compromise T cell response against prostate cancer leading to early tumor relapse

artículo científico publicado en 2016

Anti-HER2/Neu passive-aggressive immunotherapy

artículo científico publicado en 2014

Antigen persistence and the control of local T cell memory by migrant respiratory dendritic cells after acute virus infection

artículo científico publicado en 2010

Attenuation by targeting the B- and T-cell attenuator.

artículo científico publicado en 2011

Author Correction: A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8+ T-cell response and effective tumor control

scientific article published on 01 April 2020

Author Correction: Tumor cells suppress radiation-induced immunity by hijacking caspase 9 signaling

scientific article published on 16 September 2020

B and T lymphocyte attenuator tempers early infection immunity

artículo científico publicado en 2009

B lymphocytes induce the formation of follicular dendritic cell clusters in a lymphotoxin alpha-dependent fashion.

artículo científico publicado en 1998

B7DC/PDL2 promotes tumor immunity by a PD-1-independent mechanism.

artículo científico publicado en 2003

Blockade of lymphotoxin pathway exacerbates autoimmune arthritis by enhancing the Th1 response

scientific article published on 01 October 2005

CD160 is essential for NK-mediated IFN-γ production

artículo científico publicado en 2015

CD160 serves as a negative regulator of NKT cells in acute hepatic injury

artículo científico publicado en 2019

CD95 promotes tumour growth

artículo científico publicado en 2010

Cetuximab-mediated tumor regression depends on innate and adaptive immune responses.

artículo científico publicado en 2012

Clinical Experiences With Anti-CD137 and Anti-PD1 Therapeutic Antibodies

artículo científico publicado el 1 de octubre de 2010

Co-stimulation agonists as a new immunotherapy for autoimmune diseases.

artículo científico publicado en 2003

Commensal bacteria protect against food allergen sensitization

artículo científico publicado en 2014

Comparative impacts of glutathione peroxidase-1 gene knockout on oxidative stress induced by reactive oxygen and nitrogen species in mouse hepatocytes

artículo científico publicado en 2001

Complementary role of CD4+ T cells and secondary lymphoid tissues for cross-presentation of tumor antigen to CD8+ T cells.

artículo científico publicado en 2003

Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo

artículo científico publicado en 2006

Coordinating antigen cytosolic delivery and danger signaling to program potent cross-priming by micelle-based nanovaccine.

scientific article published on 04 April 2017

Coordinating development of medullary thymic epithelial cells

scientific article published on 01 September 2008

Coordination between NF-kappaB family members p50 and p52 is essential for mediating LTbetaR signals in the development and organization of secondary lymphoid tissues

artículo científico publicado en 2006

Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease

artículo científico publicado en 2002

Cutting Edge: Lymphotoxin Signaling Is Essential for Clearance of Salmonella from the Gut Lumen and Generation of Anti-Salmonella Protective Immunity.

artículo científico publicado en 2016

Cutting edge: B and T lymphocyte attenuator signaling on NKT cells inhibits cytokine release and tissue injury in early immune responses.

artículo científico publicado en 2009

Cytokine regulation of secondary lymphoid organ development.

artículo científico publicado en 1998

Cytokines that target immune killer cells against tumors

scientific article published on 10 June 2020

De novo prediction of cancer-associated T cell receptors for noninvasive cancer detection

artículo científico publicado en 2020

Decreased macrophage-mediated cytotoxicity in mammary-tumor-bearing mice is related to alteration of nitric-oxide production and/or release.

artículo científico publicado en 1995

Deficiency of CD40 Reveals an Important Role for LIGHT in Anti-Leishmania Immunity

artículo científico publicado en 2015

Deflating the Lymph Node

artículo científico publicado el 28 de enero de 2011

Development and maturation of secondary lymphoid tissues.

artículo científico publicado en 1999

Differential regulation of breast cancer bone metastasis by PARP1 and PARP2

scientific article published on 27 March 2020

Direct and indirect roles of the LTbetaR pathway in central tolerance induction.

artículo científico publicado en 2010

Distinct Roles of Lymphotoxin α and the Type I Tumor Necrosis Factor (TNF) Receptor in the Establishment of Follicular Dendritic Cells from Non–Bone Marrow–derived Cells

artículo científico publicado el 15 de diciembre de 1997

Do adaptive immune cells suppress or activate innate immunity?

scientific article published on 06 December 2008

Dual-targeting nanoparticle vaccine elicits a therapeutic antibody response against chronic hepatitis B

artículo científico publicado en 2020

Dynamic programmed death 1 expression by virus-specific CD8 T cells correlates with the outcome of acute hepatitis B.

artículo científico publicado en 2008

Effective anti-neu-initiated antitumor responses require the complex role of CD4+ T cells.

artículo científico publicado en 2013

Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity

artículo científico publicado en 2015

Enhanced induction of dendritic cell maturation and HLA-A*0201-restricted CEA-specific CD8(+) CTL response by exosomes derived from IL-18 gene-modified CEA-positive tumor cells.

artículo científico publicado en 2006

Enhanced local delivery with reduced systemic toxicity: delivery, delivery, and delivery.

artículo científico publicado en 2006

Essential role of lymph nodes in contact hypersensitivity revealed in lymphotoxin-alpha-deficient mice.

artículo científico publicado en 2001

Facilitating T Cell Infiltration in Tumor Microenvironment Overcomes Resistance to PD-L1 Blockade

scientific journal article

Food-induced asthma in China: an analysis in 40 cases.

artículo científico publicado en 1991

From DNA Damage to Nucleic Acid Sensing: A Strategy to Enhance Radiation Therapy

artículo científico

GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation

artículo científico publicado en 2015

Gadd45beta promotes hepatocyte survival during liver regeneration in mice by modulating JNK signaling

artículo científico publicado en 2008

Group 3 innate lymphoid cells inhibit T-cell-mediated intestinal inflammation through aryl hydrocarbon receptor signaling and regulation of microflora.

artículo científico publicado en 2013

Growth-factor receptor-bound protein-2 (Grb2) signaling in B cells controls lymphoid follicle organization and germinal center reaction.

artículo científico publicado en 2011

Hepatitis B virus infection and immunopathogenesis in a humanized mouse model: induction of human-specific liver fibrosis and M2-like macrophages

artículo científico publicado en 2014

Host STING-dependent MDSC mobilization drives extrinsic radiation resistance.

artículo científico publicado en 2017

Hybrid cellular membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis

artículo científico publicado en 2020

Hypofractionated EGFR tyrosine kinase inhibitor limits tumor relapse through triggering innate and adaptive immunity

scientific article published on 01 August 2019

IgE regulates T helper cell differentiation through FcgammaRIII mediated dendritic cell cytokine modulation.

artículo científico publicado en 2010

Immunology. Autoreactive B cells migrate into T cell territory

scientific article published on 01 September 2002

Immunoregulation by tumor necrosis factor superfamily member LIGHT

artículo científico publicado en 2009

Immunotherapy and tumor microenvironment

artículo científico

Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells

artículo científico publicado en 2002

Induction of innate lymphoid cell-derived interleukin-22 by the transcription factor STAT3 mediates protection against intestinal infection

scientific article published on 09 January 2014

Innate Lymphoid Cells Control Early Colonization Resistance against Intestinal Pathogens through ID2-Dependent Regulation of the Microbiota.

artículo científico publicado en 2015

Innate and adaptive immune cells in the tumor microenvironment

artículo científico publicado en 2013

Innate lymphoid cells facilitate NK cell development through a lymphotoxin-mediated stromal microenvironment

artículo científico publicado en 2014

Innate lymphotoxin receptor mediated signaling promotes HSV-1 associated neuroinflammation and viral replication.

artículo científico publicado en 2015

Interaction of mature CD3+CD4+ T cells with dendritic cells triggers the development of tertiary lymphoid structures in the thyroid.

artículo científico publicado en 2006

Interferon-armed RBD dimer enhances the immunogenicity of RBD for sterilizing immunity against SARS-CoV-2

artículo científico publicado en 2021

Intratumoral Delivery of IL-21 Overcomes Anti-Her2/Neu Resistance through Shifting Tumor-Associated Macrophages from M2 to M1 Phenotype.

artículo científico

Intratumoral heterogeneity impacts the response to anti-neu antibody therapy.

artículo científico publicado en 2014

Investigation of Antigen-Specific T-Cell Receptor Clusters in Human Cancers

artículo científico publicado en 2019

Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice.

artículo científico publicado en 2014

LIGHT delivery to tumors by mesenchymal stem cells mobilizes an effective antitumor immune response.

artículo científico publicado en 2012

LIGHT induces distinct signals to clear an AAV-expressed persistent antigen in the mouse liver and to induce liver inflammation

artículo científico publicado en 2010

LIGHT regulates inflamed draining lymph node hypertrophy.

artículo científico publicado en 2011

LIGHT signals directly to intestinal epithelia to cause barrier dysfunction via cytoskeletal and endocytic mechanisms.

artículo científico publicado en 2007

LIGHT/TNFSR14 can regulate hepatic lipase expression by hepatocytes independent of T cells and Kupffer cells

artículo científico publicado en 2013

LKB1 orchestrates dendritic cell metabolic quiescence and anti-tumor immunity

artículo científico publicado en 2019

Lipopolysaccharide and interferon-gamma-induced nitric oxide production and protein oxidation in mouse peritoneal macrophages are affected by glutathione peroxidase-1 gene knockout.

artículo científico publicado en 2001

Low-dose X-ray radiotherapy-radiodynamic therapy via nanoscale metal-organic frameworks enhances checkpoint blockade immunotherapy

scientific article published on 26 March 2018

Lymphoid microenvironment in the gut for immunoglobulin A and inflammation.

artículo científico publicado en 2003

Lymphotoxin beta receptor (Lt betaR): dual roles in demyelination and remyelination and successful therapeutic intervention using Lt betaR-Ig protein.

artículo científico publicado en 2007

Lymphotoxin beta receptor signaling limits mucosal damage through driving IL-23 production by epithelial cells.

artículo científico publicado en 2014

Lymphotoxin beta receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE-/- mice

artículo científico publicado en 2009

Lymphotoxin beta receptor-Ig fusion protein treatment blocks actively induced, but not adoptively transferred, uveitis in Lewis rats

scientific article published on 01 June 2003

Lymphotoxin beta receptor-dependent control of lipid homeostasis

artículo científico publicado en 2007

Lymphotoxin controls the IL-22 protection pathway in gut innate lymphoid cells during mucosal pathogen challenge.

artículo científico publicado en 2011

Lymphotoxin is required for maintaining physiological levels of serum IgE that minimizes Th1-mediated airway inflammation.

artículo científico publicado en 2003

Lymphotoxin organizes contributions to host defense and metabolic illness from innate lymphoid cells

artículo científico publicado en 2013

Lymphotoxin pathway directs thymic Aire expression

artículo científico publicado en 2003

Lymphotoxin regulates commensal responses to enable diet-induced obesity

artículo científico publicado en 2012

Lymphotoxin signalling in immune homeostasis and the control of microorganisms.

artículo científico

Membrane lymphotoxin is required for resistance to Theiler's virus infection.

artículo científico publicado en 2003

Multimodality therapy of an acquired factor V inhibitor

scientific article published on 01 April 1996

NQO1 targeting prodrug triggers innate sensing to overcome checkpoint blockade resistance

scientific article published on 19 July 2019

New immune therapy targets tumor-associated environment: from bone marrow to tumor site.

artículo científico publicado en 2011

OX40 signaling favors the induction of T(H)9 cells and airway inflammation

artículo científico publicado en 2012

PD-1 Shapes B Cells as Evildoers in the Tumor Microenvironment.

artículo científico publicado en 2016

PD-L1 on dendritic cells attenuates T cell activation and regulates response to immune checkpoint blockade

scientific article published on 24 September 2020

Phagocytosis checkpoints as new targets for cancer immunotherapy

scientific article published on 28 August 2019

Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion

artículo científico publicado en 2003

Priming of naive T cells inside tumors leads to eradication of established tumors

scientific article published on 04 January 2004

Proinflammatory IL-17 induces iBALT development

artículo científico publicado el 19 de septiembre de 2011

Promoting immune responses by LIGHT in the face of abundant regulatory T cell inhibition.

artículo científico publicado en 2009

Proteolysis-targeting chimera against BCL-X<sub>L</sub> destroys tumor-infiltrating regulatory T cells

artículo científico publicado en 2021

RIG-I-like receptor LGP2 is required for tumor control by radiation therapy

artículo científico publicado en 2020

Radiation and anti-PD-L1 antibody combinatorial therapy induces T cell-mediated depletion of myeloid-derived suppressor cells and tumor regression

artículo científico publicado en 2014

Radiation-induced equilibrium is a balance between tumor cell proliferation and T cell-mediated killing

artículo científico publicado en 2013

Radiation-induced tumor dormancy reflects an equilibrium between the proliferation and T lymphocyte-mediated death of malignant cells.

artículo científico publicado en 2013

Radiation-inducible immunotherapy for cancer: senescent tumor cells as a cancer vaccine

artículo científico publicado en 2012

Radiotherapy and immune checkpoint blockade: potential interactions and future directions.

artículo científico publicado en 2015

Recruitment and activation of naive T cells in the islets by lymphotoxin beta receptor-dependent tertiary lymphoid structure

scientific article published on 24 August 2006

Response to Field.

artículo científico publicado en 2006

Route of immunization with peptide-pulsed dendritic cells controls the distribution of memory and effector T cells in lymphoid tissues and determines the pattern of regional tumor control

artículo científico publicado en 2003

STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors.

artículo científico publicado en 2014

Secondary lymphoid organs are important but not absolutely required for allograft responses

artículo científico publicado en 2003

Signaling via LTbetaR on the lamina propria stromal cells of the gut is required for IgA production

artículo científico publicado en 2002

Small molecular drugs reshape tumor microenvironment to synergize with immunotherapy

artículo científico publicado en 2020

T cell-derived lymphotoxin limits Th1 response during HSV-1 infection

scientific article published in Scientific Reports

T cell-derived lymphotoxin regulates liver regeneration

artículo científico publicado en 2008

TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis.

artículo científico publicado en 2013

Targeting CD137 enhances the efficacy of cetuximab.

artículo científico publicado en 2014

Targeting IFNα to tumor by anti-PD-L1 creates feedforward antitumor responses to overcome checkpoint blockade resistance

scientific article published in Nature Communications

Targeting and utilizing primary tumors as live vaccines: changing strategies

artículo científico publicado el 21 de noviembre de 2011

Targeting innate sensing in the tumor microenvironment to improve immunotherapy

scientific article published on 16 December 2019

Targeting lymphotoxin-mediated negative selection to prevent prostate cancer in mice with genetic predisposition.

artículo científico publicado en 2009

The Aryl Hydrocarbon Receptor Regulates Gut Immunity through Modulation of Innate Lymphoid Cells

artículo científico publicado el 15 de diciembre de 2011

The Aryl hydrocarbon receptor mediates tobacco-induced PD-L1 expression and is associated with response to immunotherapy

scientific article published on 08 March 2019

The ETS1 transcription factor is required for the development and cytokine-induced expansion of ILC2.

artículo científico publicado en 2016

The Role of Adaptive Immunity in the Efficacy of Targeted Cancer Therapies

artículo científico publicado en 2016

The complementation of lymphotoxin deficiency with LIGHT, a newly discovered TNF family member, for the restoration of secondary lymphoid structure and function

artículo científico publicado en 2002

The complicated role of NF-kappaB in T-cell selection.

artículo científico publicado en 2010

The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity

artículo científico publicado en 2011

The human BCL6 transgene promotes the development of lymphomas in the mouse

scholarly article

The requirement of CD8+ T cells to initiate and augment acute cardiac inflammatory response to high blood pressure

artículo científico publicado en 2014

The role of LIGHT in T cell-mediated immunity.

artículo científico publicado en 2004

The role of core TNF/LIGHT family members in lymph node homeostasis and remodeling

artículo científico publicado el 1 de noviembre de 2011

The role of herpesvirus entry mediator as a negative regulator of T cell-mediated responses

artículo científico publicado en 2005

The tragic fate of group 3 innate lymphoid cells during HIV-1 infection.

artículo científico publicado en 2015

Therapeutic activity of high-dose intratumoral IFN-β requires direct effect on the tumor vasculature.

artículo científico publicado en 2014

Tissue-resident CD4<sup>+</sup> T helper cells assist the development of protective respiratory B and CD8<sup>+</sup> T cell memory responses

artículo científico publicado en 2021

Tolerogenic properties of lymphatic endothelial cells are controlled by the lymph node microenvironment

artículo científico publicado en 2014

Tumor cells suppress radiation-induced immunity by hijacking caspase 9 signaling

scientific article published on 30 March 2020

Tumor immunity meets autoimmunity: antigen levels and dendritic cell maturation.

artículo científico publicado en 2003

Tumor masses support naive T cell infiltration, activation, and differentiation into effectors

artículo científico publicado en 2010

Tumor necrosis factor family members and inflammatory bowel disease.

artículo científico publicado en 2005

Tumor-reprogrammed resident T cells resist radiation to control tumors

scientific article published on 02 September 2019

Type I interferon response and innate immune sensing of cancer

artículo científico publicado en 2013

ZMYND8 expression in breast cancer cells blocks T-lymphocyte surveillance to promote tumor growth

scientific article published on 04 November 2020