Lista de obras - Alessandro Grottesi - Dominio Público Uruguay

A Kv channel with an altered activation gate sequence displays both "fast" and "slow" activation kinetics.

artículo científico publicado en 2008

Autism with seizures and intellectual disability: possible causative role of gain-of-function of the inwardly-rectifying K+ channel Kir4.1.

artículo científico publicado en 2011

Conformational dynamics of M2 helices in KirBac channels: helix flexibility in relation to gating via molecular dynamics simulations.

artículo científico publicado en 2005

Conformational dynamics of the ligand-binding domain of inward rectifier K channels as revealed by molecular dynamics simulations: toward an understanding of Kir channel gating.

artículo científico publicado en 2005

Conformational switch of a flexible loop in human laminin receptor determines laminin-1 interaction ⬇️

artículo científico publicado el 1 de marzo de 2012

Contribution of the central hydrophobic residue in the PXP motif of voltage-dependent K+ channels to S6 flexibility and gating properties

artículo científico publicado en 2009

Diverse driving forces underlie the invariant occurrence of the T42A, E139D, I282V and T468M SHP2 amino acid substitutions causing Noonan and LEOPARD syndromes

artículo científico publicado en 2008

Dynamic effects of mutations within two loops of cytochrome c551 from Pseudomonas aeruginosa

artículo científico publicado en 2003

Early events in protein aggregation: molecular flexibility and hydrophobicity/charge interaction in amyloid peptides as studied by molecular dynamics simulations

artículo científico publicado en 2005

Episodic ataxia type 1 mutations affect fast inactivation of K+ channels by a reduction in either subunit surface expression or affinity for inactivation domain.

artículo científico publicado en 2011

Genetically induced dysfunctions of Kir2.1 channels: implications for short QT3 syndrome and autism-epilepsy phenotype.

artículo científico publicado en 2014

Insight into the mechanism of inactivation and pH sensitivity in potassium channels from molecular dynamics simulations.

artículo científico publicado en 2008

Ion channel gates: comparative analysis of energy barriers.

artículo científico publicado en 2008

Ion channel gating: insights via molecular simulations.

artículo científico publicado en 2003

Modeling conformational transitions in kinases by molecular dynamics simulations: achievements, difficulties, and open challenges

artículo científico

Molecular dynamics simulation approaches to K channels: conformational flexibility and physiological function.

artículo científico publicado en 2005

Molecular dynamics simulations of a K+ channel blocker: Tc1 toxin from Tityus cambridgei.

artículo científico publicado en 2003

Molecular dynamics study of a hyperthermophilic and a mesophilic rubredoxin

artículo científico publicado en 2002

Novel phenotype associated with a mutation in the KCNA1(Kv1.1) gene

artículo científico publicado en 2014

Outer membrane proteins: comparing X-ray and NMR structures by MD simulations in lipid bilayers.

artículo científico publicado en 2007

Parametrisation of the free energy of ATP binding to wild-type and mutant Kir6.2 potassium channels

artículo científico publicado en 2012

Revisiting the "satisfaction of spatial restraints" approach of MODELLER for protein homology modeling

scientific article published on 17 December 2019

Solution conformation of the Pseudomonas syringae MSU 16H phytotoxic lipodepsipeptide Pseudomycin A determined by computer simulations using distance geometry and molecular dynamics from NMR data.

artículo científico publicado en 1998

Structural and dynamic analysis of G558R mutation in chicken TSHR gene shows altered signal transduction and corroborates its role as a domestication gene

artículo científico publicado en 2019

Temporary secondary structures in tau, an intrinsically disordered protein

artículo científico publicado en 2012

The conformation of peptide thymosin alpha 1 in solution and in a membrane-like environment by circular dichroism and NMR spectroscopy. A possible model for its interaction with the lymphocyte membrane.

artículo científico publicado en 1998

The intrinsic flexibility of the Kv voltage sensor and its implications for channel gating.

artículo científico publicado en 2005

Vstx1, a modifier of Kv channel gating, localizes to the interfacial region of lipid bilayers

scientific article published on 01 October 2006

Lista de obras de Alessandro Grottesi

A Kv channel with an altered activation gate sequence displays both "fast" and "slow" activation kinetics.

Autism with seizures and intellectual disability: possible causative role of gain-of-function of the inwardly-rectifying K+ channel Kir4.1.

Conformational dynamics of M2 helices in KirBac channels: helix flexibility in relation to gating via molecular dynamics simulations.

Conformational dynamics of the ligand-binding domain of inward rectifier K channels as revealed by molecular dynamics simulations: toward an understanding of Kir channel gating.

Conformational switch of a flexible loop in human laminin receptor determines laminin-1 interaction ⬇️

Contribution of the central hydrophobic residue in the PXP motif of voltage-dependent K+ channels to S6 flexibility and gating properties

Diverse driving forces underlie the invariant occurrence of the T42A, E139D, I282V and T468M SHP2 amino acid substitutions causing Noonan and LEOPARD syndromes

Dynamic effects of mutations within two loops of cytochrome c551 from Pseudomonas aeruginosa

Early events in protein aggregation: molecular flexibility and hydrophobicity/charge interaction in amyloid peptides as studied by molecular dynamics simulations

Episodic ataxia type 1 mutations affect fast inactivation of K+ channels by a reduction in either subunit surface expression or affinity for inactivation domain.

Genetically induced dysfunctions of Kir2.1 channels: implications for short QT3 syndrome and autism-epilepsy phenotype.

Insight into the mechanism of inactivation and pH sensitivity in potassium channels from molecular dynamics simulations.

Ion channel gates: comparative analysis of energy barriers.

Ion channel gating: insights via molecular simulations.

Modeling conformational transitions in kinases by molecular dynamics simulations: achievements, difficulties, and open challenges

Molecular dynamics simulation approaches to K channels: conformational flexibility and physiological function.

Molecular dynamics simulations of a K+ channel blocker: Tc1 toxin from Tityus cambridgei.

Molecular dynamics study of a hyperthermophilic and a mesophilic rubredoxin

Novel phenotype associated with a mutation in the KCNA1(Kv1.1) gene

Outer membrane proteins: comparing X-ray and NMR structures by MD simulations in lipid bilayers.

Parametrisation of the free energy of ATP binding to wild-type and mutant Kir6.2 potassium channels

Revisiting the "satisfaction of spatial restraints" approach of MODELLER for protein homology modeling

Solution conformation of the Pseudomonas syringae MSU 16H phytotoxic lipodepsipeptide Pseudomycin A determined by computer simulations using distance geometry and molecular dynamics from NMR data.

Structural and dynamic analysis of G558R mutation in chicken TSHR gene shows altered signal transduction and corroborates its role as a domestication gene

Temporary secondary structures in tau, an intrinsically disordered protein

The conformation of peptide thymosin alpha 1 in solution and in a membrane-like environment by circular dichroism and NMR spectroscopy. A possible model for its interaction with the lymphocyte membrane.

The intrinsic flexibility of the Kv voltage sensor and its implications for channel gating.

Vstx1, a modifier of Kv channel gating, localizes to the interfacial region of lipid bilayers