Lista de obras - Angela Greco - Dominio Público Uruguay

9p21 locus analysis in high-risk gastrointestinal stromal tumors characterized for c-kit and platelet-derived growth factor receptor alpha gene alterations.

artículo científico publicado en 2005

A new mutation in the KIT ATP pocket causes acquired resistance to imatinib in a gastrointestinal stromal tumor patient

artículo científico publicado en 2004

Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer.

artículo científico publicado en 2004

Analysis of SHP-1-mediated down-regulation of the TRK-T3 oncoprotein identifies Trk-fused gene (TFG) as a novel SHP-1-interacting protein.

artículo científico publicado en 2004

Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells.

artículo científico publicado en 2010

Are two better than one? A novel double-mutant KIT in GIST that responds to Imatinib

artículo científico publicado en 2013

Biological activity of the thyroid TRK-T3 oncogene requires signalling through Shc

artículo científico publicado en 2002

Biological activity of the thyroid TRK-T3 oncogene requires signalling through Shc

artículo científico publicado en 2016

Characterization of the NTRK1 genomic region involved in chromosomal rearrangements generating TRK oncogenes.

artículo científico publicado en 1993

Concomitant downregulation of proliferation/survival pathways dependent on FGF-R3, JAK2 and BCMA in human multiple myeloma cells by multi-kinase targeting.

artículo científico publicado en 2009

DUSP6/MKP3 is overexpressed in papillary and poorly differentiated thyroid carcinoma and contributes to neoplastic properties of thyroid cancer cells.

artículo científico publicado en 2013

Detection of novel mRNA splice variants of human ING4 tumor suppressor gene.

artículo científico publicado en 2007

Detection of overexpressed and phosphorylated wild-type kit receptor in surgical specimens of small cell lung cancer

artículo científico publicado en 2004

Evidence of oncogene-induced senescence in thyroid carcinogenesis.

artículo científico publicado en 2011

Expression of ligand-activated KIT and platelet-derived growth factor receptor beta tyrosine kinase receptors in synovial sarcoma

artículo científico publicado en 2004

Functional analyses and molecular modeling of two c-Kit mutations responsible for imatinib secondary resistance in GIST patients

article

Functional characterization of NTRK1 mutations identified in melanoma

artículo científico publicado en 2014

Functional characterization of the MTC-associated germline RET-K666E mutation: evidence of oncogenic potential enhanced by the G691S polymorphism.

artículo científico publicado en 2011

Functional mapping of receptor tyrosine kinases in myxoid liposarcoma.

artículo científico publicado en 2010

Gain of function mutations of RTK conserved residues display differential effects on NTRK1 kinase activity.

artículo científico publicado en 2002

Genetic profiling of advanced radioactive iodine-resistant differentiated thyroid cancer and correlation with axitinib efficacy.

artículo científico publicado en 2015

Growth-inhibitory effect of STI571 on cells transformed by the COL1A1/PDGFB rearrangement.

artículo científico publicado en 2001

H2AX phosphorylation and kinetics of radiation-induced DNA double strand break repair in human primary thyrocytes.

artículo científico publicado en 2009

Histopathology, Immunohistochemistry and Molecular Biology of Follicular Epithelium-Derived Pediatric Thyroid Carcinomas

artículo científico publicado en 2016

Identification of thyroid tumor cell vulnerabilities through a siRNA-based functional screening

artículo científico publicado en 2015

Imatinib mesylate in chordoma

artículo científico publicado en 2004

Immunomodulatory Factors Control the Fate of Melanoma Tumor Initiating Cells.

artículo científico publicado en 2016

Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1 oncogene

artículo científico publicado en 2005

Integrated ligand-receptor bioinformatic and in vitro functional analysis identifies active TGFA/EGFR signaling loop in papillary thyroid carcinomas

artículo científico publicado en 2010

KRAS and BRAF mutations predict primary resistance to imatinib in gastrointestinal stromal tumors

artículo científico publicado en 2012

Loss of function effect of RET mutations causing Hirschsprung disease.

artículo científico publicado en 1995

Metallothionein 1G acts as an oncosupressor in papillary thyroid carcinoma

artículo científico publicado en 2008

Metallothionein 1G and zinc sensitize human colorectal cancer cells to chemotherapy

artículo científico publicado en 2014

Molecular spectrum of BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias: implication for MEK-ERK pathway activation

artículo científico publicado en 2015

Multikinase inhibitors in thyroid cancer.

artículo científico publicado en 2010

Novel Pathogenic Mechanisms of Congenital Insensitivity to Pain with Anhidrosis Genetic Disorder Unveiled by Functional Analysis of Neurotrophic Tyrosine Receptor Kinase Type 1/Nerve Growth Factor Receptor Mutations

artículo científico publicado en 2001

Oncogenic rearrangements of the NTRK1/NGF receptor.

artículo científico publicado en 2005

PDGFRalpha, PDGFRbeta and KIT expression/activation in conventional chondrosarcoma.

artículo científico publicado en 2006

Proximity ofTPRandNTRK1Rearranging Loci in Human Thyrocytes

scientific article published on 01 April 2005

RET inhibition: implications in cancer therapy.

artículo científico publicado en 2013

Rearrangements of NTRK1 gene in papillary thyroid carcinoma.

artículo científico publicado en 2009

Refined localization of the human TPR gene to chromosome 1q25 by in situ hybridization.

artículo científico publicado en 1994

Role of STAT3 in in vitro transformation triggered by TRK oncogenes

artículo científico publicado en 2010

Role of TFG sequences outside the coiled-coil domain in TRK-T3 oncogenic activation.

artículo científico publicado en 2003

S100A11 overexpression contributes to the malignant phenotype of papillary thyroid carcinoma.

artículo científico publicado en 2013

T670X KIT mutations in gastrointestinal stromal tumors: making sense of missense

artículo científico publicado en 2009

TIMP3 regulates migration, invasion and in vivo tumorigenicity of thyroid tumor cells.

artículo científico publicado en 2011

TRK-A, HER-2/neu, and KIT Expression/Activation Profiles in Salivary Gland Carcinoma

artículo científico publicado en 2008

Targeting Non-Oncogene Addiction: Focus on Thyroid Cancer

scientific article published on 04 January 2020

The M581V mutation, associated with a mild form of congenital insensitivity to pain with anhidrosis, causes partial inactivation of the NTRK1 receptor.

artículo científico publicado en 2002

The TFG protein, involved in oncogenic rearrangements, interacts with TANK and NEMO, two proteins involved in the NF-kappaB pathway.

artículo científico publicado en 2006

The modifier role of RET-G691S polymorphism in hereditary medullary thyroid carcinoma: functional characterization and expression/penetrance studies

artículo científico publicado en 2015

The molecular and gene/miRNA expression profiles of radioiodine resistant papillary thyroid cancer

artículo científico publicado en 2020

The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angio

artículo científico publicado en 2007

The signaling adapters fibroblast growth factor receptor substrate 2 and 3 are activated by the thyroid TRK oncoproteins.

artículo científico publicado en 2003

miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma.

artículo científico

Lista de obras de Angela Greco

9p21 locus analysis in high-risk gastrointestinal stromal tumors characterized for c-kit and platelet-derived growth factor receptor alpha gene alterations.

A new mutation in the KIT ATP pocket causes acquired resistance to imatinib in a gastrointestinal stromal tumor patient

Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer.

Analysis of SHP-1-mediated down-regulation of the TRK-T3 oncoprotein identifies Trk-fused gene (TFG) as a novel SHP-1-interacting protein.

Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells.

Are two better than one? A novel double-mutant KIT in GIST that responds to Imatinib

Biological activity of the thyroid TRK-T3 oncogene requires signalling through Shc

Biological activity of the thyroid TRK-T3 oncogene requires signalling through Shc

Characterization of the NTRK1 genomic region involved in chromosomal rearrangements generating TRK oncogenes.

Concomitant downregulation of proliferation/survival pathways dependent on FGF-R3, JAK2 and BCMA in human multiple myeloma cells by multi-kinase targeting.

DUSP6/MKP3 is overexpressed in papillary and poorly differentiated thyroid carcinoma and contributes to neoplastic properties of thyroid cancer cells.

Detection of novel mRNA splice variants of human ING4 tumor suppressor gene.

Detection of overexpressed and phosphorylated wild-type kit receptor in surgical specimens of small cell lung cancer

Evidence of oncogene-induced senescence in thyroid carcinogenesis.

Expression of ligand-activated KIT and platelet-derived growth factor receptor beta tyrosine kinase receptors in synovial sarcoma

Functional analyses and molecular modeling of two c-Kit mutations responsible for imatinib secondary resistance in GIST patients

Functional characterization of NTRK1 mutations identified in melanoma

Functional characterization of the MTC-associated germline RET-K666E mutation: evidence of oncogenic potential enhanced by the G691S polymorphism.

Functional mapping of receptor tyrosine kinases in myxoid liposarcoma.

Gain of function mutations of RTK conserved residues display differential effects on NTRK1 kinase activity.

Genetic profiling of advanced radioactive iodine-resistant differentiated thyroid cancer and correlation with axitinib efficacy.

Growth-inhibitory effect of STI571 on cells transformed by the COL1A1/PDGFB rearrangement.

H2AX phosphorylation and kinetics of radiation-induced DNA double strand break repair in human primary thyrocytes.

Histopathology, Immunohistochemistry and Molecular Biology of Follicular Epithelium-Derived Pediatric Thyroid Carcinomas

Identification of thyroid tumor cell vulnerabilities through a siRNA-based functional screening

Imatinib mesylate in chordoma

Immunomodulatory Factors Control the Fate of Melanoma Tumor Initiating Cells.

Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1 oncogene

Integrated ligand-receptor bioinformatic and in vitro functional analysis identifies active TGFA/EGFR signaling loop in papillary thyroid carcinomas

KRAS and BRAF mutations predict primary resistance to imatinib in gastrointestinal stromal tumors

Loss of function effect of RET mutations causing Hirschsprung disease.

Metallothionein 1G acts as an oncosupressor in papillary thyroid carcinoma

Metallothionein 1G and zinc sensitize human colorectal cancer cells to chemotherapy

Molecular spectrum of BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias: implication for MEK-ERK pathway activation

Multikinase inhibitors in thyroid cancer.

Novel Pathogenic Mechanisms of Congenital Insensitivity to Pain with Anhidrosis Genetic Disorder Unveiled by Functional Analysis of Neurotrophic Tyrosine Receptor Kinase Type 1/Nerve Growth Factor Receptor Mutations

Oncogenic rearrangements of the NTRK1/NGF receptor.

PDGFRalpha, PDGFRbeta and KIT expression/activation in conventional chondrosarcoma.

Proximity ofTPRandNTRK1Rearranging Loci in Human Thyrocytes

RET inhibition: implications in cancer therapy.

Rearrangements of NTRK1 gene in papillary thyroid carcinoma.

Refined localization of the human TPR gene to chromosome 1q25 by in situ hybridization.

Role of STAT3 in in vitro transformation triggered by TRK oncogenes

Role of TFG sequences outside the coiled-coil domain in TRK-T3 oncogenic activation.

S100A11 overexpression contributes to the malignant phenotype of papillary thyroid carcinoma.

T670X KIT mutations in gastrointestinal stromal tumors: making sense of missense

TIMP3 regulates migration, invasion and in vivo tumorigenicity of thyroid tumor cells.

TRK-A, HER-2/neu, and KIT Expression/Activation Profiles in Salivary Gland Carcinoma

Targeting Non-Oncogene Addiction: Focus on Thyroid Cancer

The M581V mutation, associated with a mild form of congenital insensitivity to pain with anhidrosis, causes partial inactivation of the NTRK1 receptor.

The TFG protein, involved in oncogenic rearrangements, interacts with TANK and NEMO, two proteins involved in the NF-kappaB pathway.

The modifier role of RET-G691S polymorphism in hereditary medullary thyroid carcinoma: functional characterization and expression/penetrance studies

The molecular and gene/miRNA expression profiles of radioiodine resistant papillary thyroid cancer

The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angio

The signaling adapters fibroblast growth factor receptor substrate 2 and 3 are activated by the thyroid TRK oncoproteins.

miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma.