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Lista de obras de Laura Gasparini

A large genomic deletion leads to enhancer adoption by the lamin B1 gene: a second path to autosomal dominant adult-onset demyelinating leukodystrophy (ADLD)

artículo científico publicado en 2015

Activity of flurbiprofen and chemically related anti-inflammatory drugs in models of Alzheimer's disease

artículo científico publicado en 2005

Advanced imaging of tau pathology in Alzheimer Disease: New perspectives from super resolution microscopy and label-free nanoscopy.

artículo científico publicado en 2016

Analysis of alpha-2-macroglobulin-2 allele as a risk factor in Alzheimer's disease.

artículo científico publicado en 2001

Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription.

scholarly article

Beta-amyloid and glutamate receptors

artículo científico publicado en 2008

CLIC1 functional expression is required for cAMP-induced neurite elongation in post-natal mouse retinal ganglion cells

artículo científico publicado en 2014

Detection of the presenilin 1 COOH-terminal fragment in the extracellular compartment: a release enhanced by apoptosis

scientific journal article

Does insulin dysfunction play a role in Alzheimer's disease?

artículo científico publicado en 2002

Dominant β-catenin mutations cause intellectual disability with recognizable syndromic features

artículo científico publicado en 2014

Dynamic regulation of microglial functions by the non-steroidal anti-inflammatory drug NCX 2216: implications for chronic treatments of neurodegenerative diseases.

artículo científico publicado en 2005

Early behavioural markers of disease in P301S tau transgenic mice

artículo científico publicado en 2009

Effect of energy shortage and oxidative stress on amyloid precursor protein metabolism in COS cells.

artículo científico publicado en 1997

Effects of antiepileptic drugs on hippocampal neurons coupled to micro-electrode arrays

artículo científico publicado en 2013

Frontotemporal dementia with tau pathology.

artículo científico publicado en 2007

Inhibition of energy metabolism down-regulates the Alzheimer related presenilin 2 gene.

artículo científico publicado en 2003

Interaction of tau protein with the dynactin complex

artículo científico publicado en 2007

Lamin B1 levels modulate differentiation into neurons during embryonic corticogenesis

artículo científico publicado en 2017

Lamin B1 overexpression increases nuclear rigidity in autosomal dominant leukodystrophy fibroblasts

artículo científico publicado en 2014

Lamin B1 protein is required for dendrite development in primary mouse cortical neurons

artículo científico publicado en 2015

Metformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathy

artículo científico publicado en 2016

Modulation of beta-amyloid metabolism by non-steroidal anti-inflammatory drugs in neuronal cell cultures.

artículo científico publicado en 2004

Modulation of iNOS expression by a nitric oxide-releasing derivative of the natural antioxidant ferulic acid in activated RAW 264.7 macrophages.

artículo científico publicado en 2006

Modulation of presenilin-1 processing by nitric oxide during apoptosis induced by serum withdrawal and glucose deprivation.

artículo científico publicado en 1999

N368-Tau fragments generated by legumain are detected only in trace amount in the insoluble Tau aggregates isolated from AD brain

scientific article published on 13 November 2019

NO-donor thiacarbocyanines as multifunctional agents for Alzheimer's disease

artículo científico publicado en 2015

Oct-1 recruitment to the nuclear envelope in adult-onset autosomal dominant leukodystrophy

scientific article published on 20 December 2012

Peripheral cells as an investigational tool for Alzheimer's disease.

artículo científico publicado en 1996

Peripheral markers in testing pathophysiological hypotheses and diagnosing Alzheimer's disease

artículo científico publicado el 1 de enero de 1998

Potential roles of insulin and IGF-1 in Alzheimer's disease.

artículo científico publicado en 2003

Presenilin 1 protein directly interacts with Bcl-2

artículo científico publicado en 1999

Resting microglia react to Aβ42 fibrils but do not detect oligomers or oligomer-induced neuronal damage

artículo científico publicado en 2014

Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling.

artículo científico publicado en 2001

Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice: effects on axonal viability.

artículo científico publicado en 2009

Tau-Driven Neuronal and Neurotrophic Dysfunction in a Mouse Model of Early Tauopathy.

artículo científico publicado en 2016

Tauopathy-induced retinal dysfunction in the P301S mutant human tau transgenic mouse.

artículo científico publicado en 2013

Testing pathophysiological hypotheses of Alzheimer's disease and pharmacological modulation of amyloid precursor protein metabolism: the contribution from the studies on cultured fibroblasts from affected donors.

artículo científico publicado en 1997