Lista de obras - Gina Lisignoli - Dominio Público Uruguay

A Novel H2S-releasing Amino-Bisphosphonate which combines bone anti-catabolic and anabolic functions.

artículo científico publicado en 2017

A fluorescent in situ hybridization method in flow cytometry to detect HIV-1 specific RNA.

artículo científico publicado en 1996

A multifaced DNA ploidy analysis to determine ovarian carcinoma aggressiveness

scientific article published on 01 April 1991

Adipose Mesenchymal Stromal Cell-Based Therapy for Severe Osteoarthritis of the Knee: A Phase I Dose-Escalation Trial.

scientific article published on 23 May 2016

Adipose mesenchymal stem cells protect chondrocytes from degeneration associated with osteoarthritis

artículo científico publicado en 2013

Adipose stromal cells mediated switching of the pro-inflammatory profile of M1-like macrophages is facilitated by PGE2: in vitro evaluation.

artículo científico publicado en 2017

Adipose-derived mesenchymal stem cells exert antiinflammatory effects on chondrocytes and synoviocytes from osteoarthritis patients through prostaglandin E2.

artículo científico publicado en 2013

Age-independent effects of hyaluronan amide derivative and growth hormone on human osteoarthritic chondrocytes

artículo científico publicado en 2015

An elevated number of differentiated osteoblast colonies can be obtained from rat bone marrow stromal cells using a gradient isolation procedure.

artículo científico publicado en 2001

Analysis of mesenchymal stem cells grown on a three-dimensional HYAFF 11-based prototype ligament scaffold.

artículo científico publicado en 2005

Biomaterials: Foreign Bodies or Tuners for the Immune Response? ⬇️

artículo científico

Bone osteoblastic and mesenchymal stromal cells lack primarily tumoral features in multiple myeloma patients

artículo científico publicado en 2010

CC-chemokine ligand 20/macrophage inflammatory protein-3α and CC-chemokine receptor 6 are overexpressed in myeloma microenvironment related to osteolytic bone lesions.

artículo científico publicado en 2008

CCL20 chemokine induces both osteoblast proliferation and osteoclast differentiation: Increased levels of CCL20 are expressed in subchondral bone tissue of rheumatoid arthritis patients

artículo científico publicado en 2007

CCL20/CCR6 chemokine/receptor expression in bone tissue from osteoarthritis and rheumatoid arthritis patients: different response of osteoblasts in the two groups.

artículo científico publicado en 2009

CXCL12 (SDF-1) and CXCL13 (BCA-1) chemokines significantly induce proliferation and collagen type I expression in osteoblasts from osteoarthritis patients

CXCL12 chemokine up-regulates bone resorption and MMP-9 release by human osteoclasts: CXCL12 levels are increased in synovial and bone tissue of rheumatoid arthritis patients.

artículo científico publicado en 2004

Cartilage and Bone Serum Biomarkers as Novel Tools for Monitoring Knee Osteochondritis Dissecans Treated with Osteochondral Scaffold

artículo científico publicado en 2018

Cellular and molecular events during chondrogenesis of human mesenchymal stromal cells grown in a three-dimensional hyaluronan based scaffold

artículo científico publicado en 2005

Chemokine expression by subchondral bone marrow stromal cells isolated from osteoarthritis (OA) and rheumatoid arthritis (RA) patients.

artículo científico publicado en 1999

Chitosan-based scaffold counteracts hypertrophic and fibrotic markers in chondrogenic differentiated mesenchymal stromal cells

scientific article published on 20 August 2019

Chondrogenic differentiation of murine and human mesenchymal stromal cells in a hyaluronic acid scaffold: differences in gene expression and cell morphology.

artículo científico publicado en 2006

Chondrogenic potential of Slug-depleted human mesenchymal stem cells

artículo científico publicado en 2014

Chondrogenic potential of human mesenchymal stem cells and expression of Slug transcription factor

artículo científico publicado en 2013

Clinical and Biological Signature of Osteochondritis Dissecans in a Cross-Sectional Study.

artículo científico publicado en 2018

Co-culture of hematopoietic stem/progenitor cells with human osteblasts favours mono/macrophage differentiation at the expense of the erythroid lineage.

artículo científico publicado en 2013

Collagen type XV and the 'osteogenic status'.

artículo científico publicado en 2017

Comparison of alternative mesenchymal stem cell sources for cell banking and musculoskeletal advanced therapies

artículo científico publicado en 2011

Distinct transcriptional profiles characterize bone microenvironment mesenchymal cells rather than osteoblasts in relationship with multiple myeloma bone disease.

artículo científico publicado en 2009

Distinctive expression pattern of cystathionine-β-synthase and cystathionine-γ-lyase identifies mesenchymal stromal cells transition to mineralizing osteoblasts

artículo científico publicado en 2017

Effect of microfragmented adipose tissue on osteoarthritic synovial macrophage factors

scientific article published on 06 September 2018

Epitope specificity of Th0/Th2 CD4+ T-lymphocyte clones induced by vaccination with rHBsAg vaccine

artículo científico publicado en 1997

Evidence for redifferentiation of human chondrocytes grown on a hyaluronan-based biomaterial (HYAff 11): molecular, immunohistochemical and ultrastructural analysis

article

Evidence of specific characteristics and osteogenic potentiality in bone cells from tibia

article

Expression of CXC chemokines and their receptors is modulated during chondrogenic differentiation of human mesenchymal stem cells grown in three-dimensional scaffold: evidence in native cartilage.

artículo científico publicado en 2008

Extracellular calcium chronically induced human osteoblasts effects: specific modulation of osteocalcin and collagen type XV.

artículo científico publicado en 2012

Focal Defects of the Knee Articular Surface: Evidence of a Regenerative Potential Pattern in Osteochondritis Dissecans and Degenerative Lesions.

artículo científico publicado en 2017

From osteoarthritic synovium to synovial-derived cells characterization: synovial macrophages are key effector cells.

artículo científico publicado en 2016

Gene array profile identifies collagen type XV as a novel human osteoblast-secreted matrix protein

artículo científico publicado en 2009

HOXB7 expression by myeloma cells regulates their pro-angiogenic properties in multiple myeloma patients.

artículo científico publicado en 2010

Histological and immunohistochemical analysis of an allogenic bone graft engineered with autologous bone marrow mononuclear cells in the treatment of a large segmental defect of the ulna. A case report.

artículo científico publicado en 2008

Human osteoblasts express functional CXC chemokine receptors 3 and 5: activation by their ligands, CXCL10 and CXCL13, significantly induces alkaline phosphatase and beta-N-acetylhexosaminidase release

artículo científico publicado en 2003

Human osteoclasts express different CXC chemokines depending on cell culture substrate: molecular and immunocytochemical evidence of high levels of CXCL10 and CXCL12.

artículo científico publicado en 2003

Hyaluronan does not affect cytokine and chemokine expression in osteoarthritic chondrocytes and synoviocytes.

artículo científico publicado en 2001

Hyaluronan-based polymer scaffold modulates the expression of inflammatory and degradative factors in mesenchymal stem cells: Involvement of Cd44 and Cd54.

artículo científico publicado en 2006

Hypoxia Preconditioning of Human MSCs: a Direct Evidence of HIF-1α and Collagen Type XV Correlation

artículo científico publicado en 2018

IL1-beta and TNF-alpha induce changes in the nuclear polyphosphoinositide signalling system in osteoblasts similar to that occurring in patients with rheumatoid arthritis: an immunochemical and immunocytochemical study

artículo científico publicado en 2003

IL1beta and TNFalpha differently modulate CXCL13 chemokine in stromal cells and osteoblasts isolated from osteoarthritis patients: evidence of changes associated to cell maturation

artículo científico publicado en 2004

Immunoelectron microscopic localization of Collagen type XV during human mesenchymal stem cells mineralization

Impact of Isolation Procedures on the Development of a Preclinical Synovial Fibroblasts/Macrophages in an In Vitro Model of Osteoarthritis

artículo científico publicado en 2020

In vitro cultured stromal cells from human tonsils display a distinct phenotype and induce B cell adhesion and proliferation

artículo científico publicado en 1996

Inhibition of CD95 apoptotic signaling by interferon-gamma in human osteoarthritic chondrocytes is associated with increased expression of FLICE inhibitory protein.

artículo científico publicado en 2004

Lack of anti-inflammatory and anti-catabolic effects on basal inflamed osteoarthritic chondrocytes or synoviocytes by adipose stem cell-conditioned medium.

artículo científico publicado en 2015

Mechano-functional assessment of human mesenchymal stem cells grown in three-dimensional hyaluronan-based scaffolds for cartilage tissue engineering.

artículo científico publicado en 2010

Mineralization behavior with mesenchymal stromal cells in a biomimetic hyaluronic acid-based scaffold.

artículo científico publicado en 2010

Myeloma cells inhibit non-canonical wnt co-receptor ror2 expression in human bone marrow osteoprogenitor cells: effect of wnt5a/ror2 pathway activation on the osteogenic differentiation impairment induced by myeloma cells.

artículo científico publicado en 2012

Novel nano-composite biomimetic biomaterial allows chondrogenic and osteogenic differentiation of bone marrow concentrate derived cells

artículo científico publicado en 2015

Osteoarthritic Milieu Affects Adipose-Derived Mesenchymal Stromal Cells

artículo científico publicado en 2019

Osteoarthritis treated with mesenchymal stem cells on hyaluronan-based scaffold in rabbit

artículo científico publicado en 2009

Osteogenesis of large segmental radius defects enhanced by basic fibroblast growth factor activated bone marrow stromal cells grown on non-woven hyaluronic acid-based polymer scaffold

artículo científico publicado en 2002

Osteogenic differentiation of human MSCs: Specific occupancy of the mitochondrial DNA by NFATc1 transcription factor

artículo científico publicado en 2015

PKC-zeta expression is lower in osteoblasts from arthritic patients: IL1-beta and TNF-alpha induce a similar decrease in non-arthritic human osteoblasts

artículo científico publicado en 2008

Ploidy disturbances as an early indicator of intrinsic malignancy in endometrial carcinoma

scientific article published on 01 July 1993

Quantitative enzyme histochemistry of rat foetal brain and trigeminal ganglion.

artículo científico publicado en 1988

Quantitative immunodetection of key elements of polyphosphoinositide signal transduction in osteoblasts from arthritic patients shows a direct correlation with cell proliferation

artículo científico publicado en 2005

Rational Design and Development of Anisotropic and Mechanically Strong Gelatin-Based Stress Relaxing Hydrogels for Osteogenic/Chondrogenic Differentiation

scientific article published on 12 July 2019

Recruitment and proliferation of T lymphocytes is supported by IFNgamma- and TNFalpha-activated human osteoblasts: Involvement of CD54 (ICAM-1) and CD106 (VCAM-1) adhesion molecules and CXCR3 chemokine receptor.

artículo científico

Slug contributes to the regulation of CXCL12 expression in human osteoblasts

artículo científico publicado en 2011

Slug gene expression supports human osteoblast maturation

artículo científico publicado en 2009

Slug transcription factor and nuclear Lamin B1 are upregulated in osteoarthritic chondrocytes

artículo científico publicado en 2015

Sodium hydrosulfide inhibits the differentiation of osteoclast progenitor cells via NRF2-dependent mechanism.

artículo científico publicado en 2014

Specific concentration of hyaluronan amide derivative induces osteogenic mineralization of human mesenchymal stromal cells: Evidence of RUNX2 and COL1A1 genes modulation

artículo científico publicado en 2019

Specific inductive potential of a novel nanocomposite biomimetic biomaterial for osteochondral tissue regeneration.

artículo científico publicado en 2013

T cell subsets differently regulate osteogenic differentiation of human mesenchymal stromal cells in vitro

artículo científico publicado en 2013

T cell suppression by osteoclasts in vitro

artículo científico publicado en 2011

The expression of cystathionine gamma-lyase is regulated by estrogen receptor alpha in human osteoblasts.

artículo científico publicado en 2017

The use of microfluorometry to study DNA in nasopharyngeal carcinomas: a possible prognostic tool?

scientific article published on 01 January 1989

Thrombospondin-1 Partly Mediates the Cartilage Protective Effect of Adipose-Derived Mesenchymal Stem Cells in Osteoarthritis.

artículo científico publicado en 2017

Transcription factor decoy against NFATc1 in human primary osteoblasts

artículo científico publicado en 2011

Lista de obras de Gina Lisignoli

A Novel H2S-releasing Amino-Bisphosphonate which combines bone anti-catabolic and anabolic functions.

A fluorescent in situ hybridization method in flow cytometry to detect HIV-1 specific RNA.

A multifaced DNA ploidy analysis to determine ovarian carcinoma aggressiveness

Adipose Mesenchymal Stromal Cell-Based Therapy for Severe Osteoarthritis of the Knee: A Phase I Dose-Escalation Trial.

Adipose mesenchymal stem cells protect chondrocytes from degeneration associated with osteoarthritis

Adipose stromal cells mediated switching of the pro-inflammatory profile of M1-like macrophages is facilitated by PGE2: in vitro evaluation.

Adipose-derived mesenchymal stem cells exert antiinflammatory effects on chondrocytes and synoviocytes from osteoarthritis patients through prostaglandin E2.

Age-independent effects of hyaluronan amide derivative and growth hormone on human osteoarthritic chondrocytes

An elevated number of differentiated osteoblast colonies can be obtained from rat bone marrow stromal cells using a gradient isolation procedure.

Analysis of mesenchymal stem cells grown on a three-dimensional HYAFF 11-based prototype ligament scaffold.

Biomaterials: Foreign Bodies or Tuners for the Immune Response? ⬇️

Bone osteoblastic and mesenchymal stromal cells lack primarily tumoral features in multiple myeloma patients

CC-chemokine ligand 20/macrophage inflammatory protein-3α and CC-chemokine receptor 6 are overexpressed in myeloma microenvironment related to osteolytic bone lesions.

CCL20 chemokine induces both osteoblast proliferation and osteoclast differentiation: Increased levels of CCL20 are expressed in subchondral bone tissue of rheumatoid arthritis patients

CCL20/CCR6 chemokine/receptor expression in bone tissue from osteoarthritis and rheumatoid arthritis patients: different response of osteoblasts in the two groups.

CXCL12 (SDF-1) and CXCL13 (BCA-1) chemokines significantly induce proliferation and collagen type I expression in osteoblasts from osteoarthritis patients

CXCL12 chemokine up-regulates bone resorption and MMP-9 release by human osteoclasts: CXCL12 levels are increased in synovial and bone tissue of rheumatoid arthritis patients.

Cartilage and Bone Serum Biomarkers as Novel Tools for Monitoring Knee Osteochondritis Dissecans Treated with Osteochondral Scaffold

Cellular and molecular events during chondrogenesis of human mesenchymal stromal cells grown in a three-dimensional hyaluronan based scaffold

Chemokine expression by subchondral bone marrow stromal cells isolated from osteoarthritis (OA) and rheumatoid arthritis (RA) patients.

Chitosan-based scaffold counteracts hypertrophic and fibrotic markers in chondrogenic differentiated mesenchymal stromal cells

Chondrogenic differentiation of murine and human mesenchymal stromal cells in a hyaluronic acid scaffold: differences in gene expression and cell morphology.

Chondrogenic potential of Slug-depleted human mesenchymal stem cells

Chondrogenic potential of human mesenchymal stem cells and expression of Slug transcription factor

Clinical and Biological Signature of Osteochondritis Dissecans in a Cross-Sectional Study.

Co-culture of hematopoietic stem/progenitor cells with human osteblasts favours mono/macrophage differentiation at the expense of the erythroid lineage.

Collagen type XV and the 'osteogenic status'.

Comparison of alternative mesenchymal stem cell sources for cell banking and musculoskeletal advanced therapies

Distinct transcriptional profiles characterize bone microenvironment mesenchymal cells rather than osteoblasts in relationship with multiple myeloma bone disease.

Distinctive expression pattern of cystathionine-β-synthase and cystathionine-γ-lyase identifies mesenchymal stromal cells transition to mineralizing osteoblasts

Effect of microfragmented adipose tissue on osteoarthritic synovial macrophage factors

Epitope specificity of Th0/Th2 CD4+ T-lymphocyte clones induced by vaccination with rHBsAg vaccine

Evidence for redifferentiation of human chondrocytes grown on a hyaluronan-based biomaterial (HYAff 11): molecular, immunohistochemical and ultrastructural analysis

Evidence of specific characteristics and osteogenic potentiality in bone cells from tibia

Expression of CXC chemokines and their receptors is modulated during chondrogenic differentiation of human mesenchymal stem cells grown in three-dimensional scaffold: evidence in native cartilage.

Extracellular calcium chronically induced human osteoblasts effects: specific modulation of osteocalcin and collagen type XV.

Focal Defects of the Knee Articular Surface: Evidence of a Regenerative Potential Pattern in Osteochondritis Dissecans and Degenerative Lesions.

From osteoarthritic synovium to synovial-derived cells characterization: synovial macrophages are key effector cells.

Gene array profile identifies collagen type XV as a novel human osteoblast-secreted matrix protein

HOXB7 expression by myeloma cells regulates their pro-angiogenic properties in multiple myeloma patients.

Histological and immunohistochemical analysis of an allogenic bone graft engineered with autologous bone marrow mononuclear cells in the treatment of a large segmental defect of the ulna. A case report.

Human osteoblasts express functional CXC chemokine receptors 3 and 5: activation by their ligands, CXCL10 and CXCL13, significantly induces alkaline phosphatase and beta-N-acetylhexosaminidase release

Human osteoclasts express different CXC chemokines depending on cell culture substrate: molecular and immunocytochemical evidence of high levels of CXCL10 and CXCL12.

Hyaluronan does not affect cytokine and chemokine expression in osteoarthritic chondrocytes and synoviocytes.

Hyaluronan-based polymer scaffold modulates the expression of inflammatory and degradative factors in mesenchymal stem cells: Involvement of Cd44 and Cd54.

Hypoxia Preconditioning of Human MSCs: a Direct Evidence of HIF-1α and Collagen Type XV Correlation

IL1-beta and TNF-alpha induce changes in the nuclear polyphosphoinositide signalling system in osteoblasts similar to that occurring in patients with rheumatoid arthritis: an immunochemical and immunocytochemical study

IL1beta and TNFalpha differently modulate CXCL13 chemokine in stromal cells and osteoblasts isolated from osteoarthritis patients: evidence of changes associated to cell maturation

Immunoelectron microscopic localization of Collagen type XV during human mesenchymal stem cells mineralization

Impact of Isolation Procedures on the Development of a Preclinical Synovial Fibroblasts/Macrophages in an In Vitro Model of Osteoarthritis

In vitro cultured stromal cells from human tonsils display a distinct phenotype and induce B cell adhesion and proliferation

Inhibition of CD95 apoptotic signaling by interferon-gamma in human osteoarthritic chondrocytes is associated with increased expression of FLICE inhibitory protein.

Lack of anti-inflammatory and anti-catabolic effects on basal inflamed osteoarthritic chondrocytes or synoviocytes by adipose stem cell-conditioned medium.

Mechano-functional assessment of human mesenchymal stem cells grown in three-dimensional hyaluronan-based scaffolds for cartilage tissue engineering.

Mineralization behavior with mesenchymal stromal cells in a biomimetic hyaluronic acid-based scaffold.

Myeloma cells inhibit non-canonical wnt co-receptor ror2 expression in human bone marrow osteoprogenitor cells: effect of wnt5a/ror2 pathway activation on the osteogenic differentiation impairment induced by myeloma cells.

Novel nano-composite biomimetic biomaterial allows chondrogenic and osteogenic differentiation of bone marrow concentrate derived cells

Osteoarthritic Milieu Affects Adipose-Derived Mesenchymal Stromal Cells

Osteoarthritis treated with mesenchymal stem cells on hyaluronan-based scaffold in rabbit

Osteogenesis of large segmental radius defects enhanced by basic fibroblast growth factor activated bone marrow stromal cells grown on non-woven hyaluronic acid-based polymer scaffold

Osteogenic differentiation of human MSCs: Specific occupancy of the mitochondrial DNA by NFATc1 transcription factor

PKC-zeta expression is lower in osteoblasts from arthritic patients: IL1-beta and TNF-alpha induce a similar decrease in non-arthritic human osteoblasts

Ploidy disturbances as an early indicator of intrinsic malignancy in endometrial carcinoma

Quantitative enzyme histochemistry of rat foetal brain and trigeminal ganglion.

Quantitative immunodetection of key elements of polyphosphoinositide signal transduction in osteoblasts from arthritic patients shows a direct correlation with cell proliferation

Rational Design and Development of Anisotropic and Mechanically Strong Gelatin-Based Stress Relaxing Hydrogels for Osteogenic/Chondrogenic Differentiation

Recruitment and proliferation of T lymphocytes is supported by IFNgamma- and TNFalpha-activated human osteoblasts: Involvement of CD54 (ICAM-1) and CD106 (VCAM-1) adhesion molecules and CXCR3 chemokine receptor.

Slug contributes to the regulation of CXCL12 expression in human osteoblasts

Slug gene expression supports human osteoblast maturation

Slug transcription factor and nuclear Lamin B1 are upregulated in osteoarthritic chondrocytes

Sodium hydrosulfide inhibits the differentiation of osteoclast progenitor cells via NRF2-dependent mechanism.

Specific concentration of hyaluronan amide derivative induces osteogenic mineralization of human mesenchymal stromal cells: Evidence of RUNX2 and COL1A1 genes modulation

Specific inductive potential of a novel nanocomposite biomimetic biomaterial for osteochondral tissue regeneration.

T cell subsets differently regulate osteogenic differentiation of human mesenchymal stromal cells in vitro

T cell suppression by osteoclasts in vitro

The expression of cystathionine gamma-lyase is regulated by estrogen receptor alpha in human osteoblasts.

The use of microfluorometry to study DNA in nasopharyngeal carcinomas: a possible prognostic tool?

Thrombospondin-1 Partly Mediates the Cartilage Protective Effect of Adipose-Derived Mesenchymal Stem Cells in Osteoarthritis.

Transcription factor decoy against NFATc1 in human primary osteoblasts