Filtros de búsqueda

Lista de obras de Francisco Javier Cañada Vicinay

1D saturation transfer difference NMR experiments on living cells: the DC-SIGN/oligomannose interaction

scientific article published on 01 December 2004

1H, 13C, and 15N backbone and side-chain chemical shift assignments for the 31 kDa human galectin-7 (p53-induced gene 1) homodimer, a pro-apoptotic lectin

article

1H, 13C, and 15N backbone and side-chain chemical shift assignments for the 36 proline-containing, full length 29 kDa human chimera-type galectin-3

article

A chiral pyrrolic tripodal receptor enantioselectively recognizes beta-mannose and beta-mannosides.

artículo científico publicado en 2010

A direct enzymatic synthesis of beta-D-galactopyranosyl-D-xylopyranosides and their use to evaluate rat intestinal lactase activity in vivo.

artículo científico publicado en 1996

A dynamic perspective on the molecular recognition of chitooligosaccharide ligands by hevein domains.

artículo científico publicado en 2005

A murine monoclonal antibody to glycogen: characterization of epitope-fine specificity by saturation transfer difference (STD) NMR spectroscopy and its use in mycobacterial capsular α-glucan research.

artículo científico publicado en 2015

A simple structural-based approach to prevent aminoglycoside inactivation by bacterial defense proteins. Conformational restriction provides effective protection against neomycin-B nucleotidylation by ANT4.

artículo científico publicado en 2005

Analogs of farnesylcysteine induce apoptosis in HL-60 cells

article

Application of NMR methods to the study of the interaction of natural products with biomolecular receptors.

artículo científico publicado en 2011

Applications of nuclear magnetic resonance spectroscopy and molecular modeling to the study of protein-carbohydrate interactions

artículo científico publicado el 1 de febrero de 1997

Aromatic-carbohydrate interactions: an NMR and computational study of model systems.

artículo científico publicado en 2008

Avenues to Characterize the Interactions of Extended N-Glycans with Proteins by NMR Spectroscopy: The Influenza Hemagglutinin Case

article

Beyond a Fluorescent Probe: Inhibition of Cell Division Protein FtsZ by mant-GTP Elucidated by NMR and Biochemical Approaches.

artículo científico publicado en 2015

Breaking pseudo-symmetry in multiantennary complex N-glycans using lanthanide-binding tags and NMR pseudo-contact shifts.

artículo científico publicado en 2013

Breaking the Limits in Analyzing Carbohydrate Recognition by NMR Spectroscopy: Resolving Branch-Selective Interaction of a Tetra-Antennary N-Glycan with Lectins.

artículo científico publicado en 2017

Carbohydrate-aromatic interactions

artículo científico publicado en 2012

Carbohydrate-based DNA ligands: sugar-oligoamides as a tool to study carbohydrate-nucleic acid interactions.

artículo científico publicado en 2005

Carbohydrate–Protein Interactions: A 3D View by NMR

artículo científico publicado el 15 de abril de 2011

Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors

artículo científico publicado en 2018

Characterization of caged compounds binding to proteins by NMR spectroscopy

artículo científico publicado en 2010

Chemometric Analysis of Bacterial Peptidoglycan Reveals Atypical Modifications That Empower the Cell Wall against Predatory Enzymes and Fly Innate Immunity

artículo científico publicado en 2016

Chiral diaminopyrrolic receptors for selective recognition of mannosides, part 2: a 3D view of the recognition modes by X-ray, NMR spectroscopy, and molecular modeling

artículo científico publicado en 2011

Competitive inhibitors of Helicobacter pylori type II dehydroquinase: synthesis, biological evaluation, and NMR studies.

artículo científico publicado en 2008

Conformational Plasticity in Glycomimetics: Fluorocarbamethyl-L-idopyranosides Mimic the Intrinsic Dynamic Behaviour of Natural Idose Rings.

artículo científico publicado en 2015

Conformational selection in glycomimetics: human galectin-1 only recognizes syn-Ψ-type conformations of β-1,3-linked lactose and its C-glycosyl derivative.

artículo científico

Conformational selection of glycomimetics at enzyme catalytic sites: experimental demonstration of the binding of distinct high-energy distorted conformations of C-, S-, and O-glycosides by E. Coli beta-galactosidases.

artículo científico publicado en 2002

Crystal structures of Paenibacillus polymyxa beta-glucosidase B complexes reveal the molecular basis of substrate specificity and give new insights into the catalytic machinery of family I glycosidases

artículo científico publicado en 2007

Delineating binding modes of Gal/GalNAc and structural elements of the molecular recognition of tumor-associated mucin glycopeptides by the human macrophage galactose-type lectin

artículo científico publicado en 2014

Detailed Investigation of the Immunodominant Role of O-Antigen Stoichiometric O-Acetylation as Revealed by Chemical Synthesis, Immunochemistry, Solution Conformation and STD-NMR Spectroscopy for Shigella flexneri 3a

artículo científico publicado en 2016

Determination of the bound conformation of a competitive nanomolar inhibitor of mycobacterium tuberculosis type II dehydroquinase by NMR spectroscopy

artículo científico publicado en 2006

Dietary flavonoid and isoflavone glycosides are hydrolysed by the lactase site of lactase phlorizin hydrolase

scientific article published on 01 February 2000

Differential mechanism-based labeling and unequivocal activity assignment of the two active sites of intestinal lactase/phlorizin hydrolase.

artículo científico publicado en 2000

Differential recognition of Haemophilus influenzae whole bacterial cells and isolated lipooligosaccharides by galactose-specific lectins

artículo científico publicado en 2018

Diffusion nuclear magnetic resonance spectroscopy detects substoichiometric concentrations of small molecules in protein samples

artículo científico publicado en 2009

Dissecting the essential role of anomeric β-triflates in glycosylation reactions

artículo científico publicado en 2020

Drawbacks of Dialysis Procedures for Removal of EDTA.

artículo científico publicado en 2017

Effect of a serine-to-aspartate replacement on the recognition of chitin oligosaccharides by truncated hevein. A 3D view by using NMR.

artículo científico

Enzymatic fine-tuning for 2-(6-hydroxynaphthyl) β-D-xylopyranoside synthesis catalyzed by the recombinant β-xylosidase BxTW1 from Talaromyces amestolkiae

artículo científico publicado en 2016

Escherichia coli β-galactosidase inhibitors through modifications at the aglyconic moiety: experimental evidence of conformational distortion in the molecular recognition process

artículo científico publicado en 2013

Experimental evidence for the existence of non-exo-anomeric conformations in branched oligosaccharides: NMR analysis of the structure and dynamics of aminoglycosides of the neomycin family

artículo científico publicado en 2002

Experimental evidence for the existence of non-exo-anomeric conformations in branched oligosaccharides: the neomycin-B case.

artículo científico publicado en 2002

Exploring NMR methods as a tool to select suitable fluorescent nucleotide analogues.

artículo científico publicado en 2013

Finding the Right Candidate for the Right Position: A Fast NMR-Assisted Combinatorial Method for Optimizing Nucleic Acids Binders.

artículo científico publicado en 2016

Fluorinated Carbohydrates as Lectin Ligands: (19)F-Based Direct STD Monitoring for Detection of Anomeric Selectivity.

artículo científico publicado en 2015

Fluorinated Carbohydrates as Lectin Ligands: Simultaneous Screening of a Monosaccharide Library and Chemical Mapping by <sup>19</sup>F NMR Spectroscopy

artículo científico publicado en 2020

Fluorinated carbohydrates as lectin ligands: versatile sensors in 19F-detected saturation transfer difference NMR spectroscopy.

artículo científico publicado en 2009

Fluoroacetamide Moieties as NMR Spectroscopy Probes for the Molecular Recognition of GlcNAc-Containing Sugars: Modulation of the CH-π Stacking Interactions by Different Fluorination Patterns

artículo científico publicado en 2017

Free and protein-bound carbohydrate structures.

artículo científico publicado en 1999

From dual binding site acetylcholinesterase inhibitors to allosteric modulators: A new avenue for disease-modifying drugs in Alzheimer's disease.

artículo científico

G2 and DFT rigorous description of the inversion process of oxane and thiane used as simple ring systems to model sugar components

artículo científico publicado en 2003

Glycan tagging to produce bioactive ligands for a surface plasmon resonance study via immobilization on different surfaces.

artículo científico publicado en 2009

Heparin Modulates the Mitogenic Activity of Fibroblast Growth Factor by Inducing Dimerization of its Receptor. A 3D View by Using NMR

artículo científico publicado el 12 de agosto de 2013

Hevein domains: an attractive model to study carbohydrate-protein interactions at atomic resolution

artículo científico publicado en 2006

Immobilization of thermostable β-galactosidase on epoxy support and its use for lactose hydrolysis and galactooligosaccharides biosynthesis

article

Increase of Redox Potential during the Evolution of Enzymes Degrading Recalcitrant Lignin

artículo científico publicado en 2019

Insights into real-time chemical processes in a calcium sensor protein-directed dynamic library

artículo científico publicado en 2019

Interactions of bacterial cell division protein FtsZ with C8-substituted guanine nucleotide inhibitors. A combined NMR, biochemical and molecular modeling perspective.

artículo científico publicado en 2013

Intra- and intermolecular interactions of human galectin-3: assessment by full-assignment-based NMR

artículo científico publicado en 2016

Lanthanide-chelating carbohydrate conjugates are useful tools to characterize carbohydrate conformation in solution and sensitive sensors to detect carbohydrate-protein interactions.

artículo científico

Lectin-based drug design: combined strategy to identify lead compounds using STD NMR spectroscopy, solid-phase assays and cell binding for a plant toxin model.

artículo científico

Membranes as the energy source in the endergonic transformation of vitamin A to 11-cis-retinol

scientific article published on 01 May 1989

Mite allergoids coupled to nonoxidized mannan from Saccharomyces cerevisae efficiently target canine dendritic cells for novel allergy immunotherapy in veterinary medicine.

artículo científico publicado en 2017

Modification of Proteins by Cyclopentenone Prostaglandins is Differentially Modulated by GSH in Vitro

article

Modulating glycosidase degradation and lectin recognition of gold glyconanoparticles.

artículo científico publicado en 2009

Molecular recognition of rosmarinic acid from Salvia sclareoides extracts by acetylcholinesterase: a new binding site detected by NMR spectroscopy.

artículo científico publicado en 2013

Monitoring Glycan-Protein Interactions by NMR Spectroscopic Analysis: A Simple Chemical Tag That Mimics Natural CH-π Interactions

artículo científico publicado en 2015

N-domain of human adhesion/growth-regulatory galectin-9: preference for distinct conformers and non-sialylated N-glycans and detection of ligand-induced structural changes in crystal and solution

artículo científico publicado en 2010

NMR and Molecular Recognition of N-Glycans: Remote Modifications of the Saccharide Chain Modulate Binding Features

artículo científico publicado en 2017

NMR and modeling studies of protein-carbohydrate interactions: synthesis, three-dimensional structure, and recognition properties of a minimum hevein domain with binding affinity for chitooligosaccharides.

artículo científico publicado en 2004

NMR investigations of protein-carbohydrate interactions: refined three-dimensional structure of the complex between hevein and methyl beta-chitobioside.

artículo científico publicado en 1998

NMR studies of the conformation of thiocellobiose bound to a beta-glucosidase from Streptomyces sp

scientific article published on 01 January 1998

NMR studies on the conformation of oligomannosides and their interaction with banana lectin

artículo científico publicado en 2007

New cathepsin inhibitors to explore the fluorophilic properties of the S2 pocket of cathepsin B: design, synthesis, and biological evaluation

artículo científico publicado en 2011

Novel vaccines targeting dendritic cells by coupling allergoids to nonoxidized mannan enhance allergen uptake and induce functional regulatory T cells through programmed death ligand 1.

artículo científico publicado en 2016

On the importance of carbohydrate-aromatic interactions for the molecular recognition of oligosaccharides by proteins: NMR studies of the structure and binding affinity of AcAMP2-like peptides with non-natural naphthyl and fluoroaromatic residues.

artículo científico publicado en 2005

Optimizing the enzymatic synthesis of beta-D-galactopyranosyl-D-xyloses for their use in the evaluation of lactase activity in vivo.

artículo científico publicado en 2007

Peptides derived from human galectin-3 N-terminal tail interact with its carbohydrate recognition domain in a phosphorylation-dependent manner.

artículo científico publicado en 2013

Protein molecular weight standards can compensate systematic errors in diffusion-ordered spectroscopy

artículo científico publicado en 2004

Protein-carbohydrate interactions studied by NMR: from molecular recognition to drug design

artículo científico publicado en 2012

Recent Developments in Synthetic Carbohydrate-Based Diagnostics, Vaccines, and Therapeutics.

artículo científico

Regioselectivity of the enzymatic transgalactosidation of D- and L-xylose catalysed by beta-galactosidases

scientific article published on 01 December 1997

Solution conformation of carbohydrates: a view by using NMR assisted by modeling

artículo científico publicado en 2015

Structural and Biochemical Characterization of the Interaction of Tubulin with Potent Natural Analogues of Podophyllotoxin

artículo científico publicado en 2016

Structural aspects of binding of α-linked digalactosides to human galectin-1

artículo científico publicado en 2011

Structure and Sialyllactose Binding of the Carboxy-Terminal Head Domain of the Fibre from a Siadenovirus, Turkey Adenovirus 3.

artículo científico publicado en 2015

Studies of the bound conformations of methyl alpha-lactoside and methyl beta-allolactoside to ricin B chain using transferred NOE experiments in the laboratory and rotating frames, assisted by molecular mechanics and dynamics calculations

scientific article published on 01 October 1995

Substrate specificities and mechanism in the enzymatic processing of vitamin A into 11-cis-retinol

scientific article published on 01 October 1990

Substrate specificity of small-intestinal lactase. Assessment of the role of the substrate hydroxyl groups

artículo científico publicado el 1 de octubre de 1992

Substrate specificity of small-intestinal lactase: Study of the steric effects and hydrogen bonds involved in enzyme-substrate interaction

artículo científico publicado el 10 de julio de 1995

Symmetric dithiodigalactoside: strategic combination of binding studies and detection of selectivity between a plant toxin and human lectins.

artículo científico publicado en 2011

Synthesis and conformational analysis of phosphorylated β-(1→2) linked mannosides.

artículo científico publicado en 2013

Synthesis of Spiro Carba-Sugars by Ring-Closing Metathesis

article

Synthesis of a bicyclic analog of L-iduronic acid adopting the biologically relevant 2S0 conformation.

artículo científico publicado en 2007

Synthesis, Conformational Analysis, and Evaluation as Glycosidase Inhibitors of Two Ether-Bridged Iminosugars

article

Systematic dissection of an aminopyrrolic cage receptor for β-glucopyranosides reveals the essentials for effective recognition.

artículo científico publicado en 2014

Temperature dependence of ligand–protein complex formation as reflected by saturation transfer difference NMR experiments

article

Tetrafluorination of sugars as strategy for enhancing protein-carbohydrate affinity: application to UDP-Galp mutase inhibition.

artículo científico publicado en 2013

The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR.

artículo científico publicado en 2015

The Y9P Variant of the Titin I27 Module: Structural Determinants of Its Revisited Nanomechanics.

artículo científico publicado en 2016

The conformation of the C-glycosyl analogue of N-acetyl-lactosamine in the free state and bound to a toxic plant agglutinin and human adhesion/growth-regulatory galectin-1.

artículo científico

The conformational behaviour of the C-glycosyl analogue of sulfatide studied by NMR in SDS micelles

artículo científico publicado en 2007

The gamma subunit of transducin is farnesylated

artículo científico publicado en 1990

The impact of R53C mutation on the three-dimensional structure, stability, and DNA-binding properties of the human Hesx-1 homeodomain.

artículo científico publicado en 2002

The interaction of La(3+) complexes of DOTA/DTPA glycoconjugates with the RCA(120) lectin: a saturation transfer difference NMR spectroscopic study.

artículo científico publicado en 2011

The solution conformation of C-glycosyl analogues of the sialyl-Tn antigen

scientific article published on 28 March 2007

Theoretical study of inversion and topomerization processes of substituted cyclohexanes: the relevance of the energy 3D hypersurface.

artículo científico publicado en 2005

Thioglycoligase derived from fungal GH3 β-xylosidase is a multi-glycoligase with broad acceptor tolerance

scientific article published on 25 September 2020

Unraveling Sugar Binding Modes to DC-SIGN by Employing Fluorinated Carbohydrates

scientific article published on 25 June 2019

Useful applications of DOSY experiments for the study of mushroom polysaccharides

artículo científico publicado en 2005

Vimentin filament organization and stress sensing depend on its single cysteine residue and zinc binding.

artículo científico publicado en 2015

α-N-Linked glycopeptides: conformational analysis and bioactivity as lectin ligands

artículo científico publicado en 2012

α-O-Linked Glycopeptide Mimetics: Synthesis, Conformation Analysis, and Interactions with Viscumin, a Galactoside-Binding Model Lectin

article

“Click” Saccharide/β-Lactam Hybrids for Lectin Inhibition

article