Lista de obras - Jorg Kotzka - Dominio Público Uruguay

2D-ToGo workflow: increasing feasibility and reproducibility of 2-dimensional gel electrophoresis.

artículo científico publicado en 2013

A mutation in the c-fos gene associated with congenital generalized lipodystrophy.

artículo científico publicado en 2013

A novel nonsense mutation in GCK exon 9 co-segregates with diabetes phenotype.

artículo científico publicado en 2004

A variant of the glucose transporter gene SLC2A2 modifies the glycaemic response to metformin therapy in recently diagnosed type 2 diabetes

article

ADD1/SREBP-1c mediates insulin-induced gene expression linked to the MAP kinase pathway

artículo científico publicado en 1998

Adipokinome Signatures in Obese Mouse Models Reflect Adipose Tissue Health and Are Associated with Serum Lipid Composition.

artículo científico publicado en 2019

Alteration of Liver Peroxisomal and Mitochondrial Functionality in the NZO Mouse Model of Metabolic Syndrome.

artículo científico publicado en 2017

An association between NIDDM and a GAA trinucleotide repeat polymorphism in the X25/frataxin (Friedreich's ataxia) gene

article

Association between copy-number variation on metabolic phenotypes and HDL-C levels in patients with polycystic ovary syndrome

artículo científico publicado en 2016

Association between the PPARalpha L162V polymorphism, plasma lipoprotein levels, and atherosclerotic disease in patients with diabetes mellitus type 2 and in nondiabetic controls.

artículo científico publicado en 2004

Associations between explorative dietary patterns and serum lipid levels and their interactions with ApoA5 and ApoE haplotype in patients with recently diagnosed type 2 diabetes

artículo científico publicado en 2016

CDH13 abundance interferes with adipocyte differentiation and is a novel biomarker for adipose tissue health

artículo científico publicado en 2018

Characterization of a postreceptor signaling defect that impairs cfos expression in cultured fibroblasts of a patient with insulin resistance

artículo científico publicado en 2000

Combinatorial hexapeptide ligand libraries (ProteoMiner): an innovative fractionation tool for differential quantitative clinical proteomics

artículo científico publicado en 2009

Correction of insulin resistance and the metabolic syndrome.

artículo científico publicado en 2005

Defects of insulin and IGF-1 action at receptor and postreceptor level in a patient with type A syndrome of insulin resistance

scientific article published on 01 May 1997

Divergent phenotypes in siblings with identical novel mutations in the HNF-1α gene leading to maturity onset diabetes of the young type 3

artículo científico publicado en 2016

Effect of sterol regulatory element binding protein-1a on the mitochondrial protein pattern in human liver cells detected by 2D-DIGE.

artículo científico publicado en 2005

Endogenous galactose formation in galactose-1-phosphate uridyltransferase deficiency.

artículo científico publicado en 2014

Enhancing mass spectrometry based serum profiling by a combination of free flow electrophoresis and ClinProt

artículo científico publicado en 2009

Estrogen receptor-alpha and Sp1 interact in the induction of the low density lipoprotein-receptor

artículo científico publicado en 2003

Exosomal proteins constitute an essential part of the human adipose tissue secretome

scientific article published on 28 November 2018

Fatty Liver Due to Increased de novo Lipogenesis: Alterations in the Hepatic Peroxisomal Proteome

scientific article published on 25 October 2019

Genetic variants in central metabolic genes influence some but not all relations of inflammatory markers in a collective with polycystic ovary syndrome

artículo científico publicado en 2012

Genetic variations in SREBP-1 and LXRα are not directly associated to PCOS but contribute to the physiological specifics of the syndrome ⬇️

artículo científico publicado el 4 de febrero de 2012

Identification of Mutations of the Arginine Vasopressin-Neurophysin II Gene in Two Kindreds with Familial Central Diabetes Insipidus ⬇️

artículo científico publicado el 1 de febrero de 1998

Identification of a gene variant in the master regulator of lipid metabolism SREBP-1 in a family with a novel form of severe combined hypolipidemia

artículo científico publicado en 2011

Identification of a novel mutation in the arginine vasopressin-neurophysin II gene in familial central diabetes insipidus.

artículo científico publicado en 2002

Identification of novel adipokines differential regulated in C57BL/Ks and C57BL/6.

artículo científico publicado en 2014

Identification of the Secreted Proteins Originated from Primary Human Hepatocytes and HepG2 Cells

artículo científico publicado en 2019

Identification of tyrosine phosphorylation sites in human Gab-1 protein by EGF receptor kinase in vitro.

artículo científico publicado en 1999

Inactivation of SREBP-1a Phosphorylation Prevents Fatty Liver Disease in Mice: Identification of Related Signaling Pathways by Gene Expression Profiles in Liver and Proteomes of Peroxisomes.

artículo científico publicado en 2018

Increased low grade inflammatory serum markers in patients with Polycystic ovary syndrome (PCOS) and their relationship to PPARgamma gene variants.

artículo científico publicado en 2008

Indirect calorimetry in humans: a postcalorimetric evaluation procedure for correction of metabolic monitor variability.

artículo científico publicado en 2013

Insulin Resistance and Vulnerability to Cardiac Ischemia

artículo científico publicado en 2018

Insulin-activated Erk-mitogen-activated protein kinases phosphorylate sterol regulatory element-binding Protein-2 at serine residues 432 and 455 in vivo.

artículo científico publicado en 2004

Insulin-regulated transcription factors: molecular link between insulin resistance and cardiovascular risk factors

artículo científico publicado en 2001

Investigating the adipose tissue secretome: a protocol to generate high-quality samples appropriate for comprehensive proteomic profiling

artículo científico publicado en 2015

Isolation and quality control of functional mitochondria.

artículo científico publicado en 2015

LDL cholesterol--why lower and lower?

artículo científico publicado en 2007

Lipodystrophies-Disorders of the Fatty Tissue

artículo científico publicado en 2020

Lipotoxicity as a new mechanism in metabolic syndrome. Does this explain insulin resistance?

artículo científico publicado en 2002

Liver-specific expression of transcriptionally active SREBP-1c is associated with fatty liver and increased visceral fat mass

artículo científico publicado en 2012

Mechanisms of Insulin Resistance in Primary and Secondary Nonalcoholic Fatty Liver

artículo científico publicado en 2017

Metabolic syndrome and hypertension: pathophysiology and molecular basis of insulin resistance.

artículo científico publicado en 1998

Novel Insights into the Adipokinome of Obese and Obese/Diabetic Mouse Models

artículo científico publicado en 2017

Peroxisome proliferator-activated receptor-gamma2 Pro12Ala and endothelial nitric oxide synthase-4a/b gene polymorphisms are not associated with hypertension in diabetes mellitus type 2.

artículo científico publicado en 2005

Peroxisomes compensate hepatic lipid overflow in mice with fatty liver

artículo científico publicado en 2015

Phosphorylation of sterol regulatory element-binding protein (SREBP)-1a links growth hormone action to lipid metabolism in hepatocytes.

artículo científico publicado en 2010

Phosphorylation of sterol regulatory element-binding protein (SREBP)-1c by p38 kinases, ERK and JNK influences lipid metabolism and the secretome of human liver cell line HepG2.

artículo científico publicado en 2014

Physiological Disturbance in Fatty Liver Energy Metabolism Converges on IGFBP2 Abundance and Regulation in Mice and Men

artículo científico publicado en 2020

Preparation of "functional" mitochondria: a challenging business.

artículo científico publicado en 2015

Preventing phosphorylation of sterol regulatory element-binding protein 1a by MAP-kinases protects mice from fatty liver and visceral obesity

artículo científico publicado en 2012

Primary skin fibroblasts as human model system for proteome analysis

artículo científico publicado en 2002

Regulation of the LDL receptor gene expression by hormones

artículo científico publicado el 1 de enero de 1998

Rhein, a novel Histone Deacetylase (HDAC) inhibitor with antifibrotic potency in human myocardial fibrosis

artículo científico publicado en 2020

Risk of diabetes-associated diseases in subgroups of patients with recent-onset diabetes: a 5-year follow-up study

artículo científico publicado en 2019

SREBP-1: gene regulatory key to syndrome X?

artículo científico publicado en 2002

Secretome profiling of primary human skeletal muscle cells

artículo científico publicado en 2013

So close and yet so far: mitochondria and peroxisomes are one but with specific talents.

artículo científico publicado en 2013

Specific Metabolic Profiles and Their Relationship to Insulin Resistance in Recent-Onset Type 1 and Type 2 Diabetes.

artículo científico publicado en 2016

Stabilization of atherosclerotic plaque during lipid lowering ⬇️

artículo científico publicado el 1 de diciembre de 1997

Sterol regulatory element-binding protein (SREBP)-1: gene regulatory target for insulin resistance?

artículo científico publicado en 2004

The Pro387Leu variant of protein tyrosine phosphatase-1B is not associated with diabetes mellitus type 2 in a German population.

artículo científico publicado en 2005

The adipokine sFRP4 induces insulin resistance and lipogenesis in the liver

scientific article published on 20 July 2019

The natural history of classic galactosemia: lessons from the GalNet registry

artículo científico publicado en 2019

Tissue-specific differences in the development of insulin resistance in a mouse model for type 1 diabetes

artículo científico publicado en 2014

Untargeted mass spectrometric approach in metabolic healthy offspring of patients with type 2 diabetes reveals medium-chain acylcarnitine as potential biomarker for lipid induced glucose intolerance (LGIT).

artículo científico publicado en 2016

[Combined analyses of paraoxonase-1 and IGF-2 polymorphism in polycystic ovary syndrome]

artículo científico publicado en 2009

[Mechanisms of plaque stabilization]

artículo científico publicado en 1999

[Obesity: ectopic fat distribution and the heart]

artículo científico publicado en 2010

[Plaque stabilization and endothelial protection by cholesterol synthesis inhibitors]

artículo científico publicado en 1999

[SREBP-1 and fatty liver. Clinical relevance for diabetes, obesity, dyslipidemia and atherosclerosis]

artículo científico publicado en 2012

Lista de obras de Jorg Kotzka

2D-ToGo workflow: increasing feasibility and reproducibility of 2-dimensional gel electrophoresis.

A mutation in the c-fos gene associated with congenital generalized lipodystrophy.

A novel nonsense mutation in GCK exon 9 co-segregates with diabetes phenotype.

A variant of the glucose transporter gene SLC2A2 modifies the glycaemic response to metformin therapy in recently diagnosed type 2 diabetes

ADD1/SREBP-1c mediates insulin-induced gene expression linked to the MAP kinase pathway

Adipokinome Signatures in Obese Mouse Models Reflect Adipose Tissue Health and Are Associated with Serum Lipid Composition.

Alteration of Liver Peroxisomal and Mitochondrial Functionality in the NZO Mouse Model of Metabolic Syndrome.

An association between NIDDM and a GAA trinucleotide repeat polymorphism in the X25/frataxin (Friedreich's ataxia) gene

Association between copy-number variation on metabolic phenotypes and HDL-C levels in patients with polycystic ovary syndrome

Association between the PPARalpha L162V polymorphism, plasma lipoprotein levels, and atherosclerotic disease in patients with diabetes mellitus type 2 and in nondiabetic controls.

Associations between explorative dietary patterns and serum lipid levels and their interactions with ApoA5 and ApoE haplotype in patients with recently diagnosed type 2 diabetes

CDH13 abundance interferes with adipocyte differentiation and is a novel biomarker for adipose tissue health

Characterization of a postreceptor signaling defect that impairs cfos expression in cultured fibroblasts of a patient with insulin resistance

Combinatorial hexapeptide ligand libraries (ProteoMiner): an innovative fractionation tool for differential quantitative clinical proteomics

Correction of insulin resistance and the metabolic syndrome.

Defects of insulin and IGF-1 action at receptor and postreceptor level in a patient with type A syndrome of insulin resistance

Divergent phenotypes in siblings with identical novel mutations in the HNF-1α gene leading to maturity onset diabetes of the young type 3

Effect of sterol regulatory element binding protein-1a on the mitochondrial protein pattern in human liver cells detected by 2D-DIGE.

Endogenous galactose formation in galactose-1-phosphate uridyltransferase deficiency.

Enhancing mass spectrometry based serum profiling by a combination of free flow electrophoresis and ClinProt

Estrogen receptor-alpha and Sp1 interact in the induction of the low density lipoprotein-receptor

Exosomal proteins constitute an essential part of the human adipose tissue secretome

Fatty Liver Due to Increased de novo Lipogenesis: Alterations in the Hepatic Peroxisomal Proteome

Genetic variants in central metabolic genes influence some but not all relations of inflammatory markers in a collective with polycystic ovary syndrome

Genetic variations in SREBP-1 and LXRα are not directly associated to PCOS but contribute to the physiological specifics of the syndrome ⬇️

Identification of Mutations of the Arginine Vasopressin-Neurophysin II Gene in Two Kindreds with Familial Central Diabetes Insipidus ⬇️

Identification of a gene variant in the master regulator of lipid metabolism SREBP-1 in a family with a novel form of severe combined hypolipidemia

Identification of a novel mutation in the arginine vasopressin-neurophysin II gene in familial central diabetes insipidus.

Identification of novel adipokines differential regulated in C57BL/Ks and C57BL/6.

Identification of the Secreted Proteins Originated from Primary Human Hepatocytes and HepG2 Cells

Identification of tyrosine phosphorylation sites in human Gab-1 protein by EGF receptor kinase in vitro.

Inactivation of SREBP-1a Phosphorylation Prevents Fatty Liver Disease in Mice: Identification of Related Signaling Pathways by Gene Expression Profiles in Liver and Proteomes of Peroxisomes.

Increased low grade inflammatory serum markers in patients with Polycystic ovary syndrome (PCOS) and their relationship to PPARgamma gene variants.

Indirect calorimetry in humans: a postcalorimetric evaluation procedure for correction of metabolic monitor variability.

Insulin Resistance and Vulnerability to Cardiac Ischemia

Insulin-activated Erk-mitogen-activated protein kinases phosphorylate sterol regulatory element-binding Protein-2 at serine residues 432 and 455 in vivo.

Insulin-regulated transcription factors: molecular link between insulin resistance and cardiovascular risk factors

Investigating the adipose tissue secretome: a protocol to generate high-quality samples appropriate for comprehensive proteomic profiling

Isolation and quality control of functional mitochondria.

LDL cholesterol--why lower and lower?

Lipodystrophies-Disorders of the Fatty Tissue

Lipotoxicity as a new mechanism in metabolic syndrome. Does this explain insulin resistance?

Liver-specific expression of transcriptionally active SREBP-1c is associated with fatty liver and increased visceral fat mass

Mechanisms of Insulin Resistance in Primary and Secondary Nonalcoholic Fatty Liver

Metabolic syndrome and hypertension: pathophysiology and molecular basis of insulin resistance.

Novel Insights into the Adipokinome of Obese and Obese/Diabetic Mouse Models

Peroxisome proliferator-activated receptor-gamma2 Pro12Ala and endothelial nitric oxide synthase-4a/b gene polymorphisms are not associated with hypertension in diabetes mellitus type 2.

Peroxisomes compensate hepatic lipid overflow in mice with fatty liver

Phosphorylation of sterol regulatory element-binding protein (SREBP)-1a links growth hormone action to lipid metabolism in hepatocytes.

Phosphorylation of sterol regulatory element-binding protein (SREBP)-1c by p38 kinases, ERK and JNK influences lipid metabolism and the secretome of human liver cell line HepG2.

Physiological Disturbance in Fatty Liver Energy Metabolism Converges on IGFBP2 Abundance and Regulation in Mice and Men

Preparation of "functional" mitochondria: a challenging business.

Preventing phosphorylation of sterol regulatory element-binding protein 1a by MAP-kinases protects mice from fatty liver and visceral obesity

Primary skin fibroblasts as human model system for proteome analysis

Regulation of the LDL receptor gene expression by hormones

Rhein, a novel Histone Deacetylase (HDAC) inhibitor with antifibrotic potency in human myocardial fibrosis

Risk of diabetes-associated diseases in subgroups of patients with recent-onset diabetes: a 5-year follow-up study

SREBP-1: gene regulatory key to syndrome X?

Secretome profiling of primary human skeletal muscle cells

So close and yet so far: mitochondria and peroxisomes are one but with specific talents.

Specific Metabolic Profiles and Their Relationship to Insulin Resistance in Recent-Onset Type 1 and Type 2 Diabetes.

Stabilization of atherosclerotic plaque during lipid lowering ⬇️

Sterol regulatory element-binding protein (SREBP)-1: gene regulatory target for insulin resistance?

The Pro387Leu variant of protein tyrosine phosphatase-1B is not associated with diabetes mellitus type 2 in a German population.

The adipokine sFRP4 induces insulin resistance and lipogenesis in the liver

The natural history of classic galactosemia: lessons from the GalNet registry

Tissue-specific differences in the development of insulin resistance in a mouse model for type 1 diabetes

Untargeted mass spectrometric approach in metabolic healthy offspring of patients with type 2 diabetes reveals medium-chain acylcarnitine as potential biomarker for lipid induced glucose intolerance (LGIT).

[Combined analyses of paraoxonase-1 and IGF-2 polymorphism in polycystic ovary syndrome]

[Mechanisms of plaque stabilization]

[Obesity: ectopic fat distribution and the heart]

[Plaque stabilization and endothelial protection by cholesterol synthesis inhibitors]

[SREBP-1 and fatty liver. Clinical relevance for diabetes, obesity, dyslipidemia and atherosclerosis]