Lista de obras - Wayne D Tilley - Dominio Público Uruguay

5alpha-Reductase type 2 gene variant associations with prostate cancer risk, circulating hormone levels and androgenetic alopecia

artículo científico publicado en 2007

A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer.

artículo científico publicado en 2016

A gene signature identified using a mouse model of androgen receptor-dependent prostate cancer predicts biochemical relapse in human disease

artículo científico publicado en 2012

A novel polymorphism in a forkhead box A1 (FOXA1) binding site of the human UDP glucuronosyltransferase 2B17 gene modulates promoter activity and is associated with altered levels of circulating androstane-3α,17β-diol glucuronide

artículo científico publicado en 2010

A patient-derived explant (PDE) model of hormone-dependent cancer

artículo científico publicado en 2018

A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer

artículo científico publicado en 2018

Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease

artículo científico publicado en 2014

An Analysis of a Multiple Biomarker Panel to Better Predict Prostate Cancer Metastasis After Radical Prostatectomy

artículo científico publicado en 2018

An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer

artículo científico publicado en 2021

Androgen Receptor Protein Levels Are Significantly Reduced in Serous Ovarian Carcinomas Compared with Benign or Borderline Disease but Are Not altered by Cancer Stage or Metastatic Progression ⬇️

artículo científico publicado el 27 de febrero de 2013

Androgen Receptor Signalling Promotes a Luminal Phenotype in Mammary Epithelial Cells

artículo científico publicado en 2018

Androgen Resistance Associated with a Mutation of the Androgen Receptor at Amino Acid 772 (Arg→Cys) Results from a Combination of Decreased Messenger Ribonucleic Acid Levels and Impairment of Receptor Function* ⬇️

artículo científico publicado el 1 de agosto de 1991

Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.

artículo científico publicado en 2016

Androgen metabolic genes in prostate cancer predisposition and progression.

artículo científico publicado en 2005

Androgen receptor coregulators and their involvement in the development and progression of prostate cancer.

artículo científico publicado en 2007

Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1

Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1.

artículo científico publicado en 2011

Androgen receptor signaling in castration-resistant prostate cancer: a lesson in persistence

artículo científico publicado en 2016

Anti-proliferative transcriptional effects of medroxyprogesterone acetate in estrogen receptor positive breast cancer cells are predominantly mediated by the progesterone receptor

artículo científico publicado en 2019

Apolipoprotein-D: a novel cellular marker for HGPIN and prostate cancer.

artículo científico publicado en 2004

Breast and prostate cancer: more similar than different.

scientific article published on 11 February 2010

Bringing androgens up a NOTCH in breast cancer

artículo científico publicado en 2014

Cancer-associated genes can affect somatic intrachromosomal recombination early in carcinogenesis.

artículo científico publicado en 2004

Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target

artículo científico publicado en 2015

Circulating Insulin-Like Growth Factor-I and Binding Protein-3 and Risk of Prostate Cancer

artículo científico publicado en 2006

Circulating steroid hormone concentrations in postmenopausal women in relation to body size and composition

artículo científico publicado en 2008

Circulating steroid hormone levels and risk of breast cancer for postmenopausal women

artículo científico publicado en 2010

Circulating steroid hormones and the risk of prostate cancer

artículo científico publicado en 2006

Co-targeting AR and HSP90 suppresses prostate cancer cell growth and prevents resistance mechanisms

artículo científico publicado en 2015

Comparative biomarker expression and RNA integrity in biospecimens derived from radical retropubic and robot-assisted laparoscopic prostatectomies

artículo científico publicado en 2010

Complexities of androgen receptor signalling in breast cancer.

artículo científico publicado en 2014

Comprehensive assessment of estrogen receptor beta antibodies in cancer cell line models and tissue reveals critical limitations in reagent specificity

artículo científico publicado en 2016

Corepressor effect on androgen receptor activity varies with the length of the CAG encoded polyglutamine repeat and is dependent on receptor/corepressor ratio in prostate cancer cells.

artículo científico publicado en 2011

Corrigendum to "Comprehensive assessment of estrogen receptor beta antibodies in cancer cell line models and tissue reveals critical limitations in reagent specificity" [Mol. Cell Endocrinol. 440 (2016) 138-150]

scientific article published on 01 March 2017

Cyclin-Dependent Kinase 2 Inhibitors in Cancer Therapy: An Update

scientific article published on 20 December 2018

Deciphering the divergent roles of progestogens in breast cancer

artículo científico publicado en 2016

Disrupting Androgen Receptor Signaling Induces Snail-Mediated Epithelial-Mesenchymal Plasticity in Prostate Cancer

artículo científico publicado en 2017

Distinct nuclear receptor expression in stroma adjacent to breast tumors.

artículo científico publicado en 2013

Dynamic methylation of histone H3 at lysine 4 in transcriptional regulation by the androgen receptor.

artículo científico publicado en 2003

ELAC2/HPC2 polymorphisms, prostate-specific antigen levels, and prostate cancer

artículo científico publicado en 2003

Elevated levels of FOXA1 facilitate androgen receptor chromatin binding resulting in a CRPC-like phenotype

artículo científico publicado en 2013

Elevated levels of HER-2/neu and androgen receptor in clinically localized prostate cancer identifies metastatic potential.

artículo científico

Epithelial plasticity in prostate cancer: principles and clinical perspectives

artículo científico

Erratum to: IκBα mediates prostate cancer cell death induced by combinatorial targeting of the androgen receptor

artículo científico publicado en 2016

Erratum: Corrigendum: Progesterone receptor modulates ERα action in breast cancer

scientific article published in Nature

Estrogen receptor beta in prostate cancer: friend or foe?

artículo científico publicado en 2014

Expression and localisation of c-kit and KITL in the adult human ovary.

artículo científico publicado en 2015

Expression of androgen receptor splice variants in clinical breast cancers.

artículo científico publicado en 2015

Finding the place of histone deacetylase inhibitors in prostate cancer therapy.

artículo científico publicado en 2009

Formation of hyaluronan- and versican-rich pericellular matrix by prostate cancer cells promotes cell motility.

artículo científico publicado en 2007

Genomic agonism and phenotypic antagonism between estrogen and progesterone receptors in breast cancer.

artículo científico publicado en 2016

Global levels of specific histone modifications and an epigenetic gene signature predict prostate cancer progression and development

artículo científico publicado en 2010

Hormone status selects for spontaneous somatic androgen receptor variants that demonstrate specific ligand and cofactor dependent activities in autochthonous prostate cancer.

artículo científico publicado en 2000

Hormones and cancer: new insights, new challenges.

artículo científico publicado en 2001

Hsp90: Still a viable target in prostate cancer ⬇️

artículo científico publicado el 31 de diciembre de 2012

Human seminal fluid as a source of prostate cancer-specific microRNA biomarkers

article

Identification of androgen receptor splice variant transcripts in breast cancer cell lines and human tissues.

artículo científico publicado en 2014

Immunohistochemical level of unsulfated chondroitin disaccharides in the cancer stroma is an independent predictor of prostate cancer relapse.

artículo científico publicado en 2008

Improved relapse-free survival on aromatase inhibitors in breast cancer is associated with interaction between oestrogen receptor-α and progesterone receptor-b

artículo científico publicado en 2018

Inhibition of T47D human breast cancer cell growth by the synthetic progestin R5020: effects of serum, estradiol, insulin, and EGF ⬇️

artículo científico publicado el 1 de diciembre de 1991

Interplay between the androgen receptor signaling axis and microRNAs in prostate cancer

scientific article published on 01 May 2019

Knockdown of the cochaperone SGTA results in the suppression of androgen and PI3K/Akt signaling and inhibition of prostate cancer cell proliferation.

artículo científico publicado en 2013

MicroRNA-194 Promotes Prostate Cancer Metastasis by Inhibiting SOCS2.

artículo científico publicado en 2016

Molecular basis of androgen resistance

artículo científico publicado el 1 de febrero de 1992

Mouse GDF9 decreases KITL gene expression in human granulosa cells

artículo científico publicado en 2014

Multiple nuclear receptor signaling pathways mediate the actions of synthetic progestins in target cells ⬇️

artículo científico publicado el 16 de septiembre de 2011

New Opportunities for Targeting the Androgen Receptor in Prostate Cancer.

artículo científico publicado en 2018

Non-canonical AR activity facilitates endocrine resistance in breast cancer

scientific article published on 01 February 2019

Novel Androgen Receptor Coregulator GRHL2 Exerts Both Oncogenic and Antimetastatic Functions in Prostate Cancer.

artículo científico publicado en 2017

Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer

artículo científico publicado en 2017

Novel twists in hormone-mediated carcinogenesis

scientific article published on 01 December 2016

Oestrogen and progesterone receptors in benign prostatic hyperplasia in humans ⬇️

artículo científico publicado el 1 de abril de 1980

Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer

artículo científico publicado en 2021

PRMT2 and RORγ expression are associated with breast cancer survival outcomes

artículo científico publicado en 2014

Patient-derived Models Reveal Impact of the Tumor Microenvironment on Therapeutic Response

scientific article published on 06 June 2018

Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy

artículo científico publicado en 2018

Progesterone receptor modulates ERα action in breast cancer

artículo científico publicado en 2015

Prostate-specific antigen and gross cystic disease fluid protein-15 are co-expressed in androgen receptor-positive breast tumours ⬇️

artículo científico publicado el 1 de agosto de 1998

Pushing estrogen receptor around in breast cancer

artículo científico publicado en 2016

Regulation of androgen receptor gene expression by steroids and retinoic acid in human breast-cancer cells

artículo científico publicado el 11 de noviembre de 1992

Regulators of genetic risk of breast cancer identified by integrative network analysis

artículo científico publicado en 2015

Renewed interest in the progesterone receptor in breast cancer

artículo científico publicado en 2016

Role of Androgen Receptor Variants in Prostate Cancer: Report from the 2017 Mission Androgen Receptor Variants Meeting.

artículo científico publicado en 2017

SGTA: A New Player in the Molecular Co-Chaperone Game ⬇️

artículo científico publicado el 2 de julio de 2013

Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha (SGTA) Ablation Limits Offspring Viability and Growth in Mice

artículo científico publicado en 2016

Structural and functional consequences of glutamine tract variation in the androgen receptor.

artículo científico publicado en 2004

Subdomain structure of the co-chaperone SGTA and activity of its androgen receptor client

scholarly article by Andrew P Trotta published in June 2012

Suberoylanilide hydroxamic acid (vorinostat) represses androgen receptor expression and acts synergistically with an androgen receptor antagonist to inhibit prostate cancer cell proliferation.

artículo científico publicado en 2007

Suppression of androgen receptor signaling in prostate cancer cells by an inhibitory receptor variant.

artículo científico publicado en 2006

Tailoring peptidomimetics for targeting protein-protein interactions

artículo científico publicado en 2014

Targeting CDK2 in cancer: challenges and opportunities for therapy

artículo científico publicado en 2019

Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies

artículo científico publicado en 2015

The 3rd Pacific Rim meeting on breast and prostate cancer: progress in hormonal carcinogenesis and the enduring influence of Ron Ross

scientific article published on 01 May 2007

The Magnitude of Androgen Receptor Positivity in Breast Cancer Is Critical for Reliable Prediction of Disease Outcome

artículo científico publicado en 2018

The dynamic and static modification of the epigenome by hormones: a role in the developmental origin of hormone related cancers.

artículo científico publicado en 2009

Uncoupling of hormone-dependence from chaperone-dependence in the L701H mutation of the androgen receptor

artículo científico publicado en 2007

Variants in the Prostate-Specific Antigen (PSA) Gene and Prostate Cancer Risk, Survival, and Circulating PSA

article

miR-200/375 control epithelial plasticity-associated alternative splicing by repressing the RNA-binding protein Quaking.

artículo científico publicado en 2018

Lista de obras de Wayne D Tilley

5alpha-Reductase type 2 gene variant associations with prostate cancer risk, circulating hormone levels and androgenetic alopecia

A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer.

A gene signature identified using a mouse model of androgen receptor-dependent prostate cancer predicts biochemical relapse in human disease

A novel polymorphism in a forkhead box A1 (FOXA1) binding site of the human UDP glucuronosyltransferase 2B17 gene modulates promoter activity and is associated with altered levels of circulating androstane-3α,17β-diol glucuronide

A patient-derived explant (PDE) model of hormone-dependent cancer

A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer

Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease

An Analysis of a Multiple Biomarker Panel to Better Predict Prostate Cancer Metastasis After Radical Prostatectomy

An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer

Androgen Receptor Protein Levels Are Significantly Reduced in Serous Ovarian Carcinomas Compared with Benign or Borderline Disease but Are Not altered by Cancer Stage or Metastatic Progression ⬇️

Androgen Receptor Signalling Promotes a Luminal Phenotype in Mammary Epithelial Cells

Androgen Resistance Associated with a Mutation of the Androgen Receptor at Amino Acid 772 (Arg→Cys) Results from a Combination of Decreased Messenger Ribonucleic Acid Levels and Impairment of Receptor Function* ⬇️

Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.

Androgen metabolic genes in prostate cancer predisposition and progression.

Androgen receptor coregulators and their involvement in the development and progression of prostate cancer.

Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1

Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1.

Androgen receptor signaling in castration-resistant prostate cancer: a lesson in persistence

Anti-proliferative transcriptional effects of medroxyprogesterone acetate in estrogen receptor positive breast cancer cells are predominantly mediated by the progesterone receptor

Apolipoprotein-D: a novel cellular marker for HGPIN and prostate cancer.

Breast and prostate cancer: more similar than different.

Bringing androgens up a NOTCH in breast cancer

Cancer-associated genes can affect somatic intrachromosomal recombination early in carcinogenesis.

Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target

Circulating Insulin-Like Growth Factor-I and Binding Protein-3 and Risk of Prostate Cancer

Circulating steroid hormone concentrations in postmenopausal women in relation to body size and composition

Circulating steroid hormone levels and risk of breast cancer for postmenopausal women

Circulating steroid hormones and the risk of prostate cancer

Co-targeting AR and HSP90 suppresses prostate cancer cell growth and prevents resistance mechanisms

Comparative biomarker expression and RNA integrity in biospecimens derived from radical retropubic and robot-assisted laparoscopic prostatectomies

Complexities of androgen receptor signalling in breast cancer.

Comprehensive assessment of estrogen receptor beta antibodies in cancer cell line models and tissue reveals critical limitations in reagent specificity

Corepressor effect on androgen receptor activity varies with the length of the CAG encoded polyglutamine repeat and is dependent on receptor/corepressor ratio in prostate cancer cells.

Corrigendum to "Comprehensive assessment of estrogen receptor beta antibodies in cancer cell line models and tissue reveals critical limitations in reagent specificity" [Mol. Cell Endocrinol. 440 (2016) 138-150]

Cyclin-Dependent Kinase 2 Inhibitors in Cancer Therapy: An Update

Deciphering the divergent roles of progestogens in breast cancer

Disrupting Androgen Receptor Signaling Induces Snail-Mediated Epithelial-Mesenchymal Plasticity in Prostate Cancer

Distinct nuclear receptor expression in stroma adjacent to breast tumors.

Dynamic methylation of histone H3 at lysine 4 in transcriptional regulation by the androgen receptor.

ELAC2/HPC2 polymorphisms, prostate-specific antigen levels, and prostate cancer

Elevated levels of FOXA1 facilitate androgen receptor chromatin binding resulting in a CRPC-like phenotype

Elevated levels of HER-2/neu and androgen receptor in clinically localized prostate cancer identifies metastatic potential.

Epithelial plasticity in prostate cancer: principles and clinical perspectives

Erratum to: IκBα mediates prostate cancer cell death induced by combinatorial targeting of the androgen receptor

Erratum: Corrigendum: Progesterone receptor modulates ERα action in breast cancer

Estrogen receptor beta in prostate cancer: friend or foe?

Expression and localisation of c-kit and KITL in the adult human ovary.

Expression of androgen receptor splice variants in clinical breast cancers.

Finding the place of histone deacetylase inhibitors in prostate cancer therapy.

Formation of hyaluronan- and versican-rich pericellular matrix by prostate cancer cells promotes cell motility.

Genomic agonism and phenotypic antagonism between estrogen and progesterone receptors in breast cancer.

Global levels of specific histone modifications and an epigenetic gene signature predict prostate cancer progression and development

Hormone status selects for spontaneous somatic androgen receptor variants that demonstrate specific ligand and cofactor dependent activities in autochthonous prostate cancer.

Hormones and cancer: new insights, new challenges.

Hsp90: Still a viable target in prostate cancer ⬇️

Human seminal fluid as a source of prostate cancer-specific microRNA biomarkers

Identification of androgen receptor splice variant transcripts in breast cancer cell lines and human tissues.

Immunohistochemical level of unsulfated chondroitin disaccharides in the cancer stroma is an independent predictor of prostate cancer relapse.

Improved relapse-free survival on aromatase inhibitors in breast cancer is associated with interaction between oestrogen receptor-α and progesterone receptor-b

Inhibition of T47D human breast cancer cell growth by the synthetic progestin R5020: effects of serum, estradiol, insulin, and EGF ⬇️

Interplay between the androgen receptor signaling axis and microRNAs in prostate cancer

Knockdown of the cochaperone SGTA results in the suppression of androgen and PI3K/Akt signaling and inhibition of prostate cancer cell proliferation.

MicroRNA-194 Promotes Prostate Cancer Metastasis by Inhibiting SOCS2.

Molecular basis of androgen resistance

Mouse GDF9 decreases KITL gene expression in human granulosa cells

Multiple nuclear receptor signaling pathways mediate the actions of synthetic progestins in target cells ⬇️

New Opportunities for Targeting the Androgen Receptor in Prostate Cancer.

Non-canonical AR activity facilitates endocrine resistance in breast cancer

Novel Androgen Receptor Coregulator GRHL2 Exerts Both Oncogenic and Antimetastatic Functions in Prostate Cancer.

Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer

Novel twists in hormone-mediated carcinogenesis

Oestrogen and progesterone receptors in benign prostatic hyperplasia in humans ⬇️

Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer

PRMT2 and RORγ expression are associated with breast cancer survival outcomes

Patient-derived Models Reveal Impact of the Tumor Microenvironment on Therapeutic Response

Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy

Progesterone receptor modulates ERα action in breast cancer

Prostate-specific antigen and gross cystic disease fluid protein-15 are co-expressed in androgen receptor-positive breast tumours ⬇️

Pushing estrogen receptor around in breast cancer