Lista de obras - Adriana Chilin - Dominio Público Uruguay

1,4,8-trimethylfuro[2,3-H]quinolin-2(1H)-one, a new furocoumarin bioisoster.

artículo científico publicado en 2004

2,6-Dimethyl-9-methoxy-4H-pyrrolo[3,2,1-ij]quinolin-4-one, a new compound with unusual photosensitizing properties

scientific article published on 01 July 1994

4-Hydroxymethyl- and 4-methoxymethylfuro[2,3-h]quinolin-2(1H)-ones: synthesis and biological properties.

artículo científico publicado en 2003

4-hydroxymethyl-1,6,8-trimethylfuro[2,3-h]quinolin-2(1H)-one induces mitochondrial dysfunction and apoptosis upon its intracellular oxidation

artículo científico publicado en 2005

8-Azapsoralen derivatives: isolation and characterization of the furan-side cycloadducts with DNA

artículo científico publicado en 1994

A novel convenient synthesis of benzoquinazolines

scientific article published on 01 January 2006

Angular furoquinolinones, psoralen analogs: novel antiproliferative agents for skin diseases. Synthesis, biological activity, mechanism of action, and computer-aided studies.

artículo científico publicado en 1996

Autogrid-based clustering of kinases: selection of representative conformations for docking purposes

artículo científico publicado en 2014

Benzoquinazoline derivatives as new agents affecting DNA processing.

artículo científico publicado en 2010

Cell killing and DNA damage induced in cultured mammalian cells by some tetrahydrobenzopsoralenquinones

scientific article published on 01 January 1999

Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships

artículo científico publicado en 2008

DNA damage and biological effects induced by photosensitization with new N(1)-unsubstituted furo[2,3-h]quinolin-2(1H)-ones.

artículo científico publicado en 2002

DNA damage induced by 4,6,8,9-tetramethyl-2H-furo[2,3-h]quinolin-2-one, a new furocoumarin analog: biological consequences

scientific article published on 01 March 2000

DNA damage induced by 4,6,8,9-tetramethyl-2H-furo[2,3-h]quinolin-2-one, a new furocoumarin analog: photochemical mechanisms

artículo científico publicado en 2000

Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB).

artículo científico publicado en 2018

Development of a novel furocoumarin derivative inhibiting NF-κB dependent biological functions: design, synthesis and biological effects

artículo científico publicado el 23 de julio de 2011

Discovery of biarylaminoquinazolines as novel tubulin polymerization inhibitors

artículo científico publicado en 2014

Mechanism of action of 4-hydroxymethyl-1,6,8-trimethylfuro[2,3-h]quinolin-2(1H)-one, a very active angular furocoumarin-like sensitizer.

artículo científico publicado en 2005

New vandetanib analogs: fused tricyclic quinazolines with antiangiogenic potential.

artículo científico publicado en 2010

New water soluble pyrroloquinoline derivatives as new potential anticancer agents

artículo científico publicado en 2005

Novel benzoquinoline derivatives via unpredicted condensation of ethyl propiolate and naphthylamines: Synthesis and topoisomerase inhibition activity

artículo científico publicado en 2016

Pegylated enzyme entrapped in poly(vinyl alcohol) hydrogel for biocatalytic application.

artículo científico publicado en 2001

Photobiological properties of 1-(3'-hydroxypropyl)-4,6,8-trimethylfur.

artículo científico publicado en 2000

Photochemical and photobiological studies on furoquinazolines as new psoralen analogs.

artículo científico publicado en 2014

Psoralen derivatives as inhibitors of NF- $$\upkappa \hbox {B/DNA}$$ κ B/DNA interaction: the critical role of the furan ring

artículo científico publicado en 2015

Psoralen derivatives as inhibitors of NF-κB/DNA interaction: synthesis, molecular modeling, 3D-QSAR, and biological evaluation

artículo científico publicado en 2013

Psoralenquinones as a novel class of proteasome inhibitors: design, synthesis and biological evaluation.

artículo científico publicado en 2011

Pyrazoloquinazoline Tricyclic System as Novel Scaffold to Design New Kinase CK2 Inhibitors

Pyrrolocoumarin derivatives: DNA-binding properties

artículo científico publicado en 1988

Pyrroloquinolinone-based dual topoisomerase I/II inhibitor

artículo científico publicado en 2014

Quinazoline derivatives as potential anticancer agents: a patent review (2007 - 2010).

artículo científico

Quinazoline-based multi-tyrosine kinase inhibitors: synthesis, modeling, antitumor and antiangiogenic properties.

artículo científico publicado en 2013

Synthesis and antitumor activity of novel amsacrine analogs: the critical role of the acridine moiety in determining their biological activity

artículo científico publicado en 2008

Synthesis and biological activity of (hydroxymethyl)- and (diethylaminomethyl)benzopsoralens

artículo científico publicado en 1999

Synthesis and biological evaluation of a new furo[2,3-h]quinolin-2(1H)-one.

artículo científico publicado en 2002

The Importance of Descriptor-Based Clusterization in QSAR Models Development: Tyrosine Kinases Inhibitors as a Key Study

artículo científico publicado en 2011

Using the TOPS-MODE approach to fit multi-target QSAR models for tyrosine kinases inhibitors

artículo científico publicado en 2011

Lista de obras de Adriana Chilin

1,4,8-trimethylfuro[2,3-H]quinolin-2(1H)-one, a new furocoumarin bioisoster.

2,6-Dimethyl-9-methoxy-4H-pyrrolo[3,2,1-ij]quinolin-4-one, a new compound with unusual photosensitizing properties

4-Hydroxymethyl- and 4-methoxymethylfuro[2,3-h]quinolin-2(1H)-ones: synthesis and biological properties.

4-hydroxymethyl-1,6,8-trimethylfuro[2,3-h]quinolin-2(1H)-one induces mitochondrial dysfunction and apoptosis upon its intracellular oxidation

8-Azapsoralen derivatives: isolation and characterization of the furan-side cycloadducts with DNA

A novel convenient synthesis of benzoquinazolines

Angular furoquinolinones, psoralen analogs: novel antiproliferative agents for skin diseases. Synthesis, biological activity, mechanism of action, and computer-aided studies.

Autogrid-based clustering of kinases: selection of representative conformations for docking purposes

Benzoquinazoline derivatives as new agents affecting DNA processing.

Cell killing and DNA damage induced in cultured mammalian cells by some tetrahydrobenzopsoralenquinones

Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships

DNA damage and biological effects induced by photosensitization with new N(1)-unsubstituted furo[2,3-h]quinolin-2(1H)-ones.

DNA damage induced by 4,6,8,9-tetramethyl-2H-furo[2,3-h]quinolin-2-one, a new furocoumarin analog: biological consequences

DNA damage induced by 4,6,8,9-tetramethyl-2H-furo[2,3-h]quinolin-2-one, a new furocoumarin analog: photochemical mechanisms

Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB).

Development of a novel furocoumarin derivative inhibiting NF-κB dependent biological functions: design, synthesis and biological effects

Discovery of biarylaminoquinazolines as novel tubulin polymerization inhibitors

Mechanism of action of 4-hydroxymethyl-1,6,8-trimethylfuro[2,3-h]quinolin-2(1H)-one, a very active angular furocoumarin-like sensitizer.

New vandetanib analogs: fused tricyclic quinazolines with antiangiogenic potential.

New water soluble pyrroloquinoline derivatives as new potential anticancer agents

Novel benzoquinoline derivatives via unpredicted condensation of ethyl propiolate and naphthylamines: Synthesis and topoisomerase inhibition activity

Pegylated enzyme entrapped in poly(vinyl alcohol) hydrogel for biocatalytic application.

Photobiological properties of 1-(3'-hydroxypropyl)-4,6,8-trimethylfur.

Photochemical and photobiological studies on furoquinazolines as new psoralen analogs.

Psoralen derivatives as inhibitors of NF- $$\upkappa \hbox {B/DNA}$$ κ B/DNA interaction: the critical role of the furan ring

Psoralen derivatives as inhibitors of NF-κB/DNA interaction: synthesis, molecular modeling, 3D-QSAR, and biological evaluation

Psoralenquinones as a novel class of proteasome inhibitors: design, synthesis and biological evaluation.

Pyrazoloquinazoline Tricyclic System as Novel Scaffold to Design New Kinase CK2 Inhibitors

Pyrrolocoumarin derivatives: DNA-binding properties

Pyrroloquinolinone-based dual topoisomerase I/II inhibitor

Quinazoline derivatives as potential anticancer agents: a patent review (2007 - 2010).

Quinazoline-based multi-tyrosine kinase inhibitors: synthesis, modeling, antitumor and antiangiogenic properties.

Synthesis and antitumor activity of novel amsacrine analogs: the critical role of the acridine moiety in determining their biological activity

Synthesis and biological activity of (hydroxymethyl)- and (diethylaminomethyl)benzopsoralens

Synthesis and biological evaluation of a new furo[2,3-h]quinolin-2(1H)-one.

The Importance of Descriptor-Based Clusterization in QSAR Models Development: Tyrosine Kinases Inhibitors as a Key Study

Using the TOPS-MODE approach to fit multi-target QSAR models for tyrosine kinases inhibitors