Lista de obras - Debora Foguel - Dominio Público Uruguay

(1)H-, (13)C- and (15)N-NMR assignment of the N-terminal domain of human cerebral dopamine neurotrophic factor (CDNF)

artículo científico publicado en 2013

3D-reconstruction and overall topology of the dimeric mitochondrial ATP synthase of the colorless alga Polytomella sp

A Metabolic Shift toward Pentose Phosphate Pathway Is Necessary for Amyloid Fibril- and Phorbol 12-Myristate 13-Acetate-induced Neutrophil Extracellular Trap (NET) Formation

artículo científico publicado en 2015

A fluorescent mutant of the NM domain of the yeast prion Sup35 provides insight into fibril formation and stability.

artículo científico publicado en 2009

Activated microglia mediate synapse loss and short-term memory deficits in a mouse model of transthyretin-related oculoleptomeningeal amyloidosis

artículo científico publicado en 2013

Age-related cognitive impairment is associated with long-term neuroinflammation and oxidative stress in a mouse model of episodic systemic inflammation.

artículo científico publicado en 2018

Amyloid fibrils trigger the release of neutrophil extracellular traps (NETs), causing fibril fragmentation by NET-associated elastase

artículo científico publicado en 2012

Amyloid properties of the leader peptide of variant B cystatin C: implications for Alzheimer and macular degeneration

scientific journal article

Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice.

artículo científico publicado en 2012

An aggregation-prone intermediate species is present in the unfolding pathway of the monomeric portal protein of bacteriophage P22: implications for portal assembly.

artículo científico publicado en 2007

An intermediate structure in the thermal unfolding of the GTPase domain of human septin 4 (SEPT4/Bradeion-beta) forms amyloid-like filaments in vitro

artículo científico publicado en 2007

An ortho-Iminoquinone Compound Reacts with Lysine Inhibiting Aggregation while Remodeling Mature Amyloid Fibrils.

artículo científico publicado en 2017

Antithrombin-mediated anticoagulant activity of sulfated polysaccharides: different mechanisms for heparin and sulfated galactans

artículo científico publicado en 2004

Applying an artificial neural network model for developing a severity score for patients with hereditary amyloid polyneuropathy

artículo científico

Astrocyte glutamate transporters are increased in an early sporadic model of synucleinopathy

artículo científico publicado en 2020

Baseline disease characteristics in Brazilian patients enrolled in Transthyretin Amyloidosis Outcome Survey (THAOS)

artículo científico publicado en 2019

Brain infusion of α-synuclein oligomers induces motor and non-motor Parkinson's disease-like symptoms in mice.

artículo científico publicado en 2017

Brazilian Science and Research Integrity: Where are We? What Next?

artículo científico publicado en 2015

Ca(2+) and Mg(2+) binding to weak sites of TnC C-domain induces exposure of a large hydrophobic surface that leads to loss of TnC from the thin filament

artículo científico publicado en 2005

Cavity defects in the procapsid of bacteriophage P22 and the mechanism of capsid maturation

scientific article published on 01 April 1999

Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation

artículo científico publicado en 2017

Characterization of a Partially Folded Monomer of the DNA-binding Domain of Human Papillomavirus E2 Protein Obtained at High Pressure

artículo científico publicado en 1998

Characterization of the unfolding process of the tetrameric and dimeric forms of Cratylia mollis seed lectin (CRAMOLL 1): effects of natural fragmentation on protein stability

artículo científico publicado en 2011

Conformational changes in human Hsp70 induced by high hydrostatic pressure produce oligomers with ATPase activity but without chaperone activity.

artículo científico publicado en 2014

Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding

artículo científico publicado en 2010

Controlling {beta}-amyloid oligomerization by the use of naphthalene sulfonates: trapping low molecular weight oligomeric species

artículo científico publicado en 2005

Correction: Structure-Based Analysis of A19D, a Variant of Transthyretin Involved in Familial Amyloid Cardiomyopathy.

artículo científico publicado en 2013

Cross Talk Between Brain Innate Immunity and Serotonin Signaling Underlies Depressive-Like Behavior Induced by Alzheimer's Amyloid-β Oligomers in Mice.

artículo científico publicado en 2016

Dissecting the structure, thermodynamic stability, and aggregation properties of the A25T transthyretin (A25T-TTR) variant involved in leptomeningeal amyloidosis: identifying protein partners that co-aggregate during A25T-TTR fibrillogenesis in [...]

artículo científico publicado en 2011

Dissociation of amyloid fibrils of alpha-synuclein and transthyretin by pressure reveals their reversible nature and the formation of water-excluded cavities

artículo científico publicado en 2003

Dopamine Affects the Stability, Hydration, and Packing of Protofibrils and Fibrils of the Wild Type and Variants of α-Synuclein†

scholarly article by Cristian Follmer et al published January 2007 in Biochemistry

Effects of high pressure and temperature on the wild-type and F29W mutant forms of the N-domain of avian troponin C.

artículo científico publicado en 1999

Effects of the Alkaloid Gramine on the Light-Harvesting, Energy Transfer, and Growth of Anabaena sp. (PCC 7119)

scientific article published on 01 February 1993

Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity.

artículo científico publicado en 2016

Fibrillar aggregates of the tumor suppressor p53 core domain

artículo científico publicado en 2003

Flavonoid interactions with human transthyretin: combined structural and thermodynamic analysis

artículo científico publicado en 2012

Fourier transform infrared spectroscopy provides a fingerprint for the tetramer and for the aggregates of transthyretin

artículo científico publicado en 2006

Free-energy linkage between folding and calcium binding in EF-hand proteins

artículo científico publicado en 2008

Geographic distribution of ATTR cases from CEPARM across the Brazilian territory and their clinical aspects, demographics, ethnical and family background

artículo científico publicado en 2019

Heterologous expression and purification of a biologically active legume lectin from Cratylia mollis seeds (CRAMOLL 1).

artículo científico publicado en 2010

High pressure studies on transthyretin.

artículo científico publicado en 2005

High-pressure applications in medicine and pharmacology

scholarly article by Jerson L Silva et al published 26 March 2004 in Journal of Physics: Condensed Matter

High-pressure chemical biology and biotechnology

artículo científico publicado en 2014

Highlights of the 3rd International Conference on High Pressure Bioscience and Biotechnology.

artículo científico publicado en 2005

Hydration and packing are crucial to amyloidogenesis as revealed by pressure studies on transthyretin variants that either protect or worsen amyloid disease

artículo científico publicado en 2003

Hydration and packing effects on prion folding and beta-sheet conversion. High pressure spectroscopy and pressure perturbation calorimetry studies

artículo científico publicado en 2004

Hydration, cavities and volume in protein folding, aggregation and amyloid assembly.

artículo científico publicado en 2009

Hydrostatic pressure induces the fusion-active state of enveloped viruses

artículo científico publicado en 2001

Hydrostatic pressure rescues native protein from aggregates

artículo científico publicado en 1999

Identification of a new variant of TTR involved in familial amyloid cardiomyopathy (FAC) in Brazil: from the patient to the protein.

artículo científico publicado en 2015

Identification of a novel ligand binding motif in the transthyretin channel

artículo científico publicado en 2010

Identification of archaeal proteins that affect the exosome function in vitro.

artículo científico publicado en 2010

Immunome and venome of Bothrops jararacussu: a proteomic approach to study the molecular immunology of snake toxins

artículo científico publicado en 2010

Inflammatory profiling of patients with familial amyloid polyneuropathy

scientific article published on 28 June 2019

Inhibition of human transthyretin aggregation by non-steroidal anti-inflammatory compounds: a structural and thermodynamic analysis

artículo científico publicado en 2013

Insights into the intramolecular coupling between the N- and C-domains of troponin C derived from high-pressure, fluorescence, nuclear magnetic resonance, and small-angle X-ray scattering studies

artículo científico publicado en 2012

Intriguing nucleic-acid-binding features of mammalian prion protein

scientific article published on 19 February 2008

LexA Repressor Forms Stable Dimers in Solution

artículo científico publicado en 2000

Ligand binding and hydration in protein misfolding: insights from studies of prion and p53 tumor suppressor proteins

artículo científico publicado en 2010

Modulation of prion protein oligomerization, aggregation, and beta-sheet conversion by 4,4'-dianilino-1,1'-binaphthyl-5,5'-sulfonate (bis-ANS).

artículo científico publicado en 2003

Neutrophil extracellular trap-enriched supernatants carry microRNAs able to modulate TNF-α production by macrophages

artículo científico publicado en 2020

New Cardiomyokine Reduces Myocardial Ischemia/Reperfusion Injury by PI3K-AKT Pathway Via a Putative KDEL-Receptor Binding

artículo científico publicado en 2020

New insights into conformational and functional stability of human alpha-thrombin probed by high hydrostatic pressure

artículo científico publicado en 2004

New insights into the mechanisms of protein misfolding and aggregation in amyloidogenic diseases derived from pressure studies

artículo científico publicado en 2004

Novel Zn2+-binding Sites in Human Transthyretin: IMPLICATIONS FOR AMYLOIDOGENESIS AND RETINOL-BINDING PROTEIN RECOGNITION

artículo científico publicado en 2010

Predictions suggesting a participation of beta-sheet configuration in the M2 domain of the P2X(7) receptor: a novel conformation?

artículo científico publicado en 2009

Pressure and low temperature effects on the fluorescence emission spectra and lifetimes of the photosynthetic components of cyanobacteria.

artículo científico publicado en 1992

Pressure induces folding intermediates that are crucial for protein-DNA recognition and virus assembly.

artículo científico publicado en 2002

Pressure-induced dissociation and denaturation of allophycocyanin at subzero temperatures.

artículo científico publicado en 1995

Pressure-temperature folding landscape in proteins involved in neurodegenerative diseases and cancer

artículo científico publicado en 2013

Protein folding and aggregation: two sides of the same coin in the condensation of proteins revealed by pressure studies

artículo científico publicado en 2005

Reciprocal remodeling upon binding of the prion protein to its signaling partner hop/STI1.

artículo científico publicado en 2009

Response to Radulescu and Brenig: Infectious nucleic acids in prion disease: halfway there

Role of Entropic Interactions in Viral Capsids: Single Amino Acid Substitutions in P22 Bacteriophage Coat Protein Resulting in Loss of Capsid Stability

artículo científico publicado en 1995

Role of hydration in the closed-to-open transition involved in Ca2+ binding by troponin C.

artículo científico publicado en 2003

Snake venomics and venom gland transcriptomic analysis of Brazilian coral snakes, Micrurus altirostris and M. corallinus

artículo científico publicado en 2011

Structural Mechanism for the Temperature-Dependent Activation of the Hyperthermophilic Pf2001 Esterase.

artículo científico publicado en 2017

Structural basis for the dissociation of α-synuclein fibrils triggered by pressure perturbation of the hydrophobic core

artículo científico publicado en 2016

Structural insights into the interaction between prion protein and nucleic acid

artículo científico

Structure-based analysis of A19D, a variant of transthyretin involved in familial amyloid cardiomyopathy

artículo científico publicado en 2013

Subunit dissociation, unfolding, and inactivation of bothrojaracin, a C-type lectin-like protein from snake venom

artículo científico publicado en 2003

Subunit-subunit interactions and overall topology of the dimeric mitochondrial ATP synthase of Polytomella sp.

artículo científico publicado en 2010

Sulfated galactan is a catalyst of antithrombin-mediated inactivation of alpha-thrombin

artículo científico publicado en 2008

Tetramerization of the LexA repressor in solution: implications for gene regulation of the E.coli SOS system at acidic pH.

artículo científico publicado en 2006

The Anti-Parkinsonian Drug Selegiline Delays the Nucleation Phase of α-Synuclein Aggregation Leading to the Formation of Nontoxic Species

article

The Solution Structure and Dynamics of Full-length Human Cerebral Dopamine Neurotrophic Factor and Its Neuroprotective Role against α-Synuclein Oligomers.

artículo científico publicado en 2015

The amino-terminal PrP domain is crucial to modulate prion misfolding and aggregation

artículo científico publicado en 2005

The binding of synthetic triiodo l-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition

artículo científico publicado en 2011

The demographic, genetic, and clinical characteristics of Brazilian subjects enrolled in the Transthyretin Amyloidosis Outcomes Survey

artículo científico publicado en 2017

The fully-active and structurally-stable form of the mitochondrial ATP synthase of Polytomella sp. is dimeric.

artículo científico publicado en 2009

The importance of a gatekeeper residue on the aggregation of transthyretin: implications for transthyretin-related amyloidoses

artículo científico publicado en 2014

The metastable state of nucleocapsids of enveloped viruses as probed by high hydrostatic pressure.

artículo científico publicado en 2000

The phenotypical expression of an European inherited TTR amyloidosis in Brazil.

artículo científico publicado en 2015

The preaggregated state of an amyloidogenic protein: hydrostatic pressure converts native transthyretin into the amyloidogenic state

scientific journal article

Trapping the monomer of a non-amyloidogenic variant of transthyretin: exploring its possible use as a therapeutic strategy against transthyretin amyloidogenic diseases.

artículo científico publicado en 2008

Volume and free energy of folding for troponin C C-domain: linkage to ion binding and N-domain interaction

artículo científico publicado en 2008

α-synuclein oligomers enhance astrocyte-induced synapse formation through TGF-β1 signaling in a Parkinson's disease model.

artículo científico publicado en 2019

Lista de obras de Debora Foguel

(1)H-, (13)C- and (15)N-NMR assignment of the N-terminal domain of human cerebral dopamine neurotrophic factor (CDNF)

3D-reconstruction and overall topology of the dimeric mitochondrial ATP synthase of the colorless alga Polytomella sp

A Metabolic Shift toward Pentose Phosphate Pathway Is Necessary for Amyloid Fibril- and Phorbol 12-Myristate 13-Acetate-induced Neutrophil Extracellular Trap (NET) Formation

A fluorescent mutant of the NM domain of the yeast prion Sup35 provides insight into fibril formation and stability.

Activated microglia mediate synapse loss and short-term memory deficits in a mouse model of transthyretin-related oculoleptomeningeal amyloidosis

Age-related cognitive impairment is associated with long-term neuroinflammation and oxidative stress in a mouse model of episodic systemic inflammation.

Amyloid fibrils trigger the release of neutrophil extracellular traps (NETs), causing fibril fragmentation by NET-associated elastase

Amyloid properties of the leader peptide of variant B cystatin C: implications for Alzheimer and macular degeneration

Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice.

An aggregation-prone intermediate species is present in the unfolding pathway of the monomeric portal protein of bacteriophage P22: implications for portal assembly.

An intermediate structure in the thermal unfolding of the GTPase domain of human septin 4 (SEPT4/Bradeion-beta) forms amyloid-like filaments in vitro

An ortho-Iminoquinone Compound Reacts with Lysine Inhibiting Aggregation while Remodeling Mature Amyloid Fibrils.

Antithrombin-mediated anticoagulant activity of sulfated polysaccharides: different mechanisms for heparin and sulfated galactans

Applying an artificial neural network model for developing a severity score for patients with hereditary amyloid polyneuropathy

Astrocyte glutamate transporters are increased in an early sporadic model of synucleinopathy

Baseline disease characteristics in Brazilian patients enrolled in Transthyretin Amyloidosis Outcome Survey (THAOS)

Brain infusion of α-synuclein oligomers induces motor and non-motor Parkinson's disease-like symptoms in mice.

Brazilian Science and Research Integrity: Where are We? What Next?

Ca(2+) and Mg(2+) binding to weak sites of TnC C-domain induces exposure of a large hydrophobic surface that leads to loss of TnC from the thin filament

Cavity defects in the procapsid of bacteriophage P22 and the mechanism of capsid maturation

Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation

Characterization of a Partially Folded Monomer of the DNA-binding Domain of Human Papillomavirus E2 Protein Obtained at High Pressure

Characterization of the unfolding process of the tetrameric and dimeric forms of Cratylia mollis seed lectin (CRAMOLL 1): effects of natural fragmentation on protein stability

Conformational changes in human Hsp70 induced by high hydrostatic pressure produce oligomers with ATPase activity but without chaperone activity.

Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding

Controlling {beta}-amyloid oligomerization by the use of naphthalene sulfonates: trapping low molecular weight oligomeric species

Correction: Structure-Based Analysis of A19D, a Variant of Transthyretin Involved in Familial Amyloid Cardiomyopathy.

Cross Talk Between Brain Innate Immunity and Serotonin Signaling Underlies Depressive-Like Behavior Induced by Alzheimer's Amyloid-β Oligomers in Mice.

Dissecting the structure, thermodynamic stability, and aggregation properties of the A25T transthyretin (A25T-TTR) variant involved in leptomeningeal amyloidosis: identifying protein partners that co-aggregate during A25T-TTR fibrillogenesis in [...]

Dissociation of amyloid fibrils of alpha-synuclein and transthyretin by pressure reveals their reversible nature and the formation of water-excluded cavities

Dopamine Affects the Stability, Hydration, and Packing of Protofibrils and Fibrils of the Wild Type and Variants of α-Synuclein†

Effects of high pressure and temperature on the wild-type and F29W mutant forms of the N-domain of avian troponin C.

Effects of the Alkaloid Gramine on the Light-Harvesting, Energy Transfer, and Growth of Anabaena sp. (PCC 7119)

Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity.

Fibrillar aggregates of the tumor suppressor p53 core domain

Flavonoid interactions with human transthyretin: combined structural and thermodynamic analysis

Fourier transform infrared spectroscopy provides a fingerprint for the tetramer and for the aggregates of transthyretin

Free-energy linkage between folding and calcium binding in EF-hand proteins

Geographic distribution of ATTR cases from CEPARM across the Brazilian territory and their clinical aspects, demographics, ethnical and family background

Heterologous expression and purification of a biologically active legume lectin from Cratylia mollis seeds (CRAMOLL 1).

High pressure studies on transthyretin.

High-pressure applications in medicine and pharmacology

High-pressure chemical biology and biotechnology

Highlights of the 3rd International Conference on High Pressure Bioscience and Biotechnology.

Hydration and packing are crucial to amyloidogenesis as revealed by pressure studies on transthyretin variants that either protect or worsen amyloid disease

Hydration and packing effects on prion folding and beta-sheet conversion. High pressure spectroscopy and pressure perturbation calorimetry studies

Hydration, cavities and volume in protein folding, aggregation and amyloid assembly.

Hydrostatic pressure induces the fusion-active state of enveloped viruses

Hydrostatic pressure rescues native protein from aggregates

Identification of a new variant of TTR involved in familial amyloid cardiomyopathy (FAC) in Brazil: from the patient to the protein.

Identification of a novel ligand binding motif in the transthyretin channel

Identification of archaeal proteins that affect the exosome function in vitro.

Immunome and venome of Bothrops jararacussu: a proteomic approach to study the molecular immunology of snake toxins

Inflammatory profiling of patients with familial amyloid polyneuropathy

Inhibition of human transthyretin aggregation by non-steroidal anti-inflammatory compounds: a structural and thermodynamic analysis

Insights into the intramolecular coupling between the N- and C-domains of troponin C derived from high-pressure, fluorescence, nuclear magnetic resonance, and small-angle X-ray scattering studies

Intriguing nucleic-acid-binding features of mammalian prion protein

LexA Repressor Forms Stable Dimers in Solution

Ligand binding and hydration in protein misfolding: insights from studies of prion and p53 tumor suppressor proteins

Modulation of prion protein oligomerization, aggregation, and beta-sheet conversion by 4,4'-dianilino-1,1'-binaphthyl-5,5'-sulfonate (bis-ANS).

Neutrophil extracellular trap-enriched supernatants carry microRNAs able to modulate TNF-α production by macrophages

New Cardiomyokine Reduces Myocardial Ischemia/Reperfusion Injury by PI3K-AKT Pathway Via a Putative KDEL-Receptor Binding

New insights into conformational and functional stability of human alpha-thrombin probed by high hydrostatic pressure

New insights into the mechanisms of protein misfolding and aggregation in amyloidogenic diseases derived from pressure studies

Novel Zn2+-binding Sites in Human Transthyretin: IMPLICATIONS FOR AMYLOIDOGENESIS AND RETINOL-BINDING PROTEIN RECOGNITION

Predictions suggesting a participation of beta-sheet configuration in the M2 domain of the P2X(7) receptor: a novel conformation?

Pressure and low temperature effects on the fluorescence emission spectra and lifetimes of the photosynthetic components of cyanobacteria.

Pressure induces folding intermediates that are crucial for protein-DNA recognition and virus assembly.

Pressure-induced dissociation and denaturation of allophycocyanin at subzero temperatures.

Pressure-temperature folding landscape in proteins involved in neurodegenerative diseases and cancer

Protein folding and aggregation: two sides of the same coin in the condensation of proteins revealed by pressure studies

Reciprocal remodeling upon binding of the prion protein to its signaling partner hop/STI1.

Response to Radulescu and Brenig: Infectious nucleic acids in prion disease: halfway there

Role of Entropic Interactions in Viral Capsids: Single Amino Acid Substitutions in P22 Bacteriophage Coat Protein Resulting in Loss of Capsid Stability

Role of hydration in the closed-to-open transition involved in Ca2+ binding by troponin C.

Snake venomics and venom gland transcriptomic analysis of Brazilian coral snakes, Micrurus altirostris and M. corallinus

Structural Mechanism for the Temperature-Dependent Activation of the Hyperthermophilic Pf2001 Esterase.

Structural basis for the dissociation of α-synuclein fibrils triggered by pressure perturbation of the hydrophobic core

Structural insights into the interaction between prion protein and nucleic acid