Lista de obras - Giuseppina Di Stefano - Dominio Público Uruguay

A conjugate of doxorubicin with lactosaminated albumin enhances the drug concentrations in all the forms of rat hepatocellular carcinomas independently of their differentiation grade

artículo científico publicado en 2006

A conjugate of lactosaminated poly-L-lysine with adenine arabinoside monophosphate, administered to mice by intramuscular route, accomplishes a selective delivery of the drug to the liver

scientific article published on 01 February 1994

A novel method for coupling doxorubicin to lactosaminated human albumin by an acid sensitive hydrazone bond: synthesis, characterization and preliminary biological properties of the conjugate.

artículo científico publicado en 2004

Adenine arabinoside monophosphate coupled to lactosaminated human albumin administered for 4 weeks in patients with chronic type B hepatitis decreased viremia without producing significant side effects

artículo científico publicado en 1996

Albumin-drug conjugates in the treatment of hepatic disorders.

artículo científico publicado en 2014

Alpha 2,6 sialylation of N-acetyllactosaminic sequences in human colorectal cancer cell lines. Relationship with non-adherent growth

artículo científico publicado en 1991

Altered glycosylation profile of purified plasma ACT from Alzheimer's disease

artículo científico publicado en 2010

Binding of the doxorubicin-lactosaminated human albumin conjugate to HCC cells is mediated by the drug moieties

artículo científico publicado en 2008

Coupling of antiviral nucleoside analogs to lactosaminated human albumin by using the imidazolides of their phosphoric esters

artículo científico publicado en 1993

Coupling of lactose molecules to the carrier protein hinders the spleen and bone marrow uptake of doxorubicin conjugated with human albumin

artículo científico publicado en 2006

Coupling to lactosaminated poly-L-lysine reduces the toxic effects of ribavirin on red blood cells.

artículo científico publicado en 1998

Doxorubicin coupled to lactosaminated albumin inhibits the growth of hepatocellular carcinomas induced in rats by diethylnitrosamine.

artículo científico publicado en 2005

Doxorubicin coupled to lactosaminated albumin: Effects on rats with liver fibrosis and cirrhosis

artículo científico publicado en 2006

Doxorubicin coupled to lactosaminated albumin: enhanced drug levels in rat hepatocarcinomas

scientific article published on 20 December 2005

Doxorubicin coupled to lactosaminated human albumin remains confined within mouse liver cells after the intracellular release from the carrier.

artículo científico publicado en 2003

Doxorubicin coupled to lactosaminated human albumin: a hepatocellular carcinoma targeted drug.

artículo científico publicado en 2008

Effect of sorafenib on the energy metabolism of hepatocellular carcinoma cells

artículo científico publicado en 2011

Elevated plasma levels of alpha-1-anti-chymotrypsin in age-related cognitive decline and Alzheimer's disease: a potential therapeutic target.

artículo científico publicado en 2008

Enhanced liver blood concentrations of adenine arabinoside accomplished by lactosaminated poly-L-lysine coupling: implications for regional chemotherapy of hepatic micrometastases

artículo científico publicado en 2000

Enhanced uptake of lactosaminated human albumin by rat hepatocarcinomas: implications for an improved chemotherapy of primary liver tumors.

artículo científico publicado en 2005

Floxuridine coupling with lactosaminated human albumin to increase drug efficacy on liver micrometastases.

artículo científico publicado en 2002

Galloflavin (CAS 568-80-9): a novel inhibitor of lactate dehydrogenase.

artículo científico publicado en 2011

Galloflavin suppresses lactate dehydrogenase activity and causes MYC downregulation in Burkitt lymphoma cells through NAD/NADH-dependent inhibition of sirtuin-1.

artículo científico publicado en 2013

Hepatotropic conjugate of adenine arabinoside monophosphate with lactosaminated poly-L-lysine. Synthesis of the carrier and pharmacological properties of the conjugate

scientific article published on 01 February 1997

Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors.

artículo científico publicado en 2015

Impairment of aerobic glycolysis by inhibitors of lactic dehydrogenase hinders the growth of human hepatocellular carcinoma cell lines.

artículo científico publicado en 2010

Increased CMP-NeuAc:Gal beta 1,4GlcNAc-R alpha 2,6 sialyltransferase activity in human colorectal cancer tissues

artículo científico publicado en 1989

Inhibition of [3H]thymidine incorporation into DNA of rat regenerating liver by 2',2'-difluorodeoxycytidine coupled to lactosaminated poly-L-lysine.

artículo científico publicado en 1999

Inhibition of hepatitis B virus replication by adenine arabinoside monophosphate coupled to lactosaminated albumin. Efficacy and minimal active dose.

artículo científico publicado en 1994

Inhibition of lactate dehydrogenase activity as an approach to cancer therapy

artículo científico publicado en 2014

Inhibition of lactic dehydrogenase as a way to increase the anti-proliferative effect of multi-targeted kinase inhibitors.

artículo científico publicado en 2010

LDH inhibition impacts on heat shock response and induces senescence of hepatocellular carcinoma cells

artículo científico publicado en 2017

Lactate dehydrogenase inhibition: exploring possible applications beyond cancer treatment

artículo científico publicado en 2016

Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells

artículo científico publicado en 2016

Lactate dehydrogenase inhibitors sensitize lymphoma cells to cisplatin without enhancing the drug effects on immortalized normal lymphocytes

artículo científico publicado en 2015

Lactosaminated human albumin, a hepatotropic carrier of drugs.

artículo científico publicado en 2010

Liver targeting of antiviral nucleoside analogues through the asialoglycoprotein receptor.

artículo científico publicado en 1997

NAD metabolism and functions: a common therapeutic target for neoplastic, metabolic and neurodegenerative diseases

artículo científico

Organ distribution of a conjugate of adenine arabinoside monophosphate with lactosaminated albumin in the rat

artículo científico publicado en 1994

Rad51/BRCA2 disruptors inhibit homologous recombination and synergize with olaparib in pancreatic cancer cells

artículo científico publicado en 2019

Synthesis and physicochemical characteristics of a liver-targeted conjugate of fluorodeoxyuridine monophosphate with lactosaminated human albumin.

artículo científico publicado en 2003

Synthesis of natural urolithin M6, a galloflavin mimetic, as a potential inhibitor of lactate dehydrogenase A.

artículo científico publicado en 2016

Synthetic Lethality Triggered by Combining Olaparib with BRCA2-Rad51 Disruptors

artículo científico publicado en 2017

The activation of lactate dehydrogenase induced by mTOR drives neoplastic change in breast epithelial cells

scientific article published in PLoS ONE

The pathogenesis of vacuoles produced in rat and mouse liver cells by a conjugate of adenine arabinoside monophosphate with lactosaminated albumin

scientific article published on 01 July 1992

Lista de obras de Giuseppina Di Stefano

A conjugate of doxorubicin with lactosaminated albumin enhances the drug concentrations in all the forms of rat hepatocellular carcinomas independently of their differentiation grade

A conjugate of lactosaminated poly-L-lysine with adenine arabinoside monophosphate, administered to mice by intramuscular route, accomplishes a selective delivery of the drug to the liver

A novel method for coupling doxorubicin to lactosaminated human albumin by an acid sensitive hydrazone bond: synthesis, characterization and preliminary biological properties of the conjugate.

Adenine arabinoside monophosphate coupled to lactosaminated human albumin administered for 4 weeks in patients with chronic type B hepatitis decreased viremia without producing significant side effects

Albumin-drug conjugates in the treatment of hepatic disorders.

Alpha 2,6 sialylation of N-acetyllactosaminic sequences in human colorectal cancer cell lines. Relationship with non-adherent growth

Altered glycosylation profile of purified plasma ACT from Alzheimer's disease

Binding of the doxorubicin-lactosaminated human albumin conjugate to HCC cells is mediated by the drug moieties

Coupling of antiviral nucleoside analogs to lactosaminated human albumin by using the imidazolides of their phosphoric esters

Coupling of lactose molecules to the carrier protein hinders the spleen and bone marrow uptake of doxorubicin conjugated with human albumin

Coupling to lactosaminated poly-L-lysine reduces the toxic effects of ribavirin on red blood cells.

Doxorubicin coupled to lactosaminated albumin inhibits the growth of hepatocellular carcinomas induced in rats by diethylnitrosamine.

Doxorubicin coupled to lactosaminated albumin: Effects on rats with liver fibrosis and cirrhosis

Doxorubicin coupled to lactosaminated albumin: enhanced drug levels in rat hepatocarcinomas

Doxorubicin coupled to lactosaminated human albumin remains confined within mouse liver cells after the intracellular release from the carrier.

Doxorubicin coupled to lactosaminated human albumin: a hepatocellular carcinoma targeted drug.

Effect of sorafenib on the energy metabolism of hepatocellular carcinoma cells

Elevated plasma levels of alpha-1-anti-chymotrypsin in age-related cognitive decline and Alzheimer's disease: a potential therapeutic target.

Enhanced liver blood concentrations of adenine arabinoside accomplished by lactosaminated poly-L-lysine coupling: implications for regional chemotherapy of hepatic micrometastases

Enhanced uptake of lactosaminated human albumin by rat hepatocarcinomas: implications for an improved chemotherapy of primary liver tumors.

Floxuridine coupling with lactosaminated human albumin to increase drug efficacy on liver micrometastases.

Galloflavin (CAS 568-80-9): a novel inhibitor of lactate dehydrogenase.

Galloflavin suppresses lactate dehydrogenase activity and causes MYC downregulation in Burkitt lymphoma cells through NAD/NADH-dependent inhibition of sirtuin-1.

Hepatotropic conjugate of adenine arabinoside monophosphate with lactosaminated poly-L-lysine. Synthesis of the carrier and pharmacological properties of the conjugate

Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors.

Impairment of aerobic glycolysis by inhibitors of lactic dehydrogenase hinders the growth of human hepatocellular carcinoma cell lines.

Increased CMP-NeuAc:Gal beta 1,4GlcNAc-R alpha 2,6 sialyltransferase activity in human colorectal cancer tissues

Inhibition of [3H]thymidine incorporation into DNA of rat regenerating liver by 2',2'-difluorodeoxycytidine coupled to lactosaminated poly-L-lysine.

Inhibition of hepatitis B virus replication by adenine arabinoside monophosphate coupled to lactosaminated albumin. Efficacy and minimal active dose.

Inhibition of lactate dehydrogenase activity as an approach to cancer therapy

Inhibition of lactic dehydrogenase as a way to increase the anti-proliferative effect of multi-targeted kinase inhibitors.

LDH inhibition impacts on heat shock response and induces senescence of hepatocellular carcinoma cells

Lactate dehydrogenase inhibition: exploring possible applications beyond cancer treatment

Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells

Lactate dehydrogenase inhibitors sensitize lymphoma cells to cisplatin without enhancing the drug effects on immortalized normal lymphocytes

Lactosaminated human albumin, a hepatotropic carrier of drugs.

Liver targeting of antiviral nucleoside analogues through the asialoglycoprotein receptor.

NAD metabolism and functions: a common therapeutic target for neoplastic, metabolic and neurodegenerative diseases

Organ distribution of a conjugate of adenine arabinoside monophosphate with lactosaminated albumin in the rat

Rad51/BRCA2 disruptors inhibit homologous recombination and synergize with olaparib in pancreatic cancer cells

Synthesis and physicochemical characteristics of a liver-targeted conjugate of fluorodeoxyuridine monophosphate with lactosaminated human albumin.

Synthesis of natural urolithin M6, a galloflavin mimetic, as a potential inhibitor of lactate dehydrogenase A.

Synthetic Lethality Triggered by Combining Olaparib with BRCA2-Rad51 Disruptors

The activation of lactate dehydrogenase induced by mTOR drives neoplastic change in breast epithelial cells

The pathogenesis of vacuoles produced in rat and mouse liver cells by a conjugate of adenine arabinoside monophosphate with lactosaminated albumin