Lista de obras - Andrew Randall - Dominio Público Uruguay

4-dimensional functional profiling in the convulsant-treated larval zebrafish brain.

artículo científico publicado en 2017

A New Player in the “Synaptopathy” of Alzheimer’s Disease – Arc/Arg 3.1 ⬇️

artículo científico publicado el 13 de febrero de 2013

A comparison of paired-pulse facilitation of AMPA and NMDA receptor-mediated excitatory postsynaptic currents in the hippocampus

artículo científico publicado en 1994

A monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons

artículo científico publicado en 2020

A unified model of CA1/3 pyramidal cells: an investigation into excitability.

artículo científico publicado en 2010

AICA riboside both activates AMP-activated protein kinase and competes with adenosine for the nucleoside transporter in the CA1 region of the rat hippocampus.

artículo científico publicado en 2004

Actions of sipatrigine, 202W92 and lamotrigine on R-type and T-type Ca2+ channel currents

artículo científico publicado en 2003

Activity-dependent depression of the spike after-depolarization generates long-lasting intrinsic plasticity in hippocampal CA3 pyramidal neurons.

artículo científico publicado en 2009

Altered Intrinsic Pyramidal Neuron Properties and Pathway-Specific Synaptic Dysfunction Underlie Aberrant Hippocampal Network Function in a Mouse Model of Tauopathy.

artículo científico publicado en 2016

Altered Synapse Stability in the Early Stages of Tauopathy

scientific article published on March 2017

Altered functional brain network connectivity and glutamate system function in transgenic mice expressing truncated Disrupted-in-Schizophrenia 1

artículo científico publicado en 2015

Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice

artículo científico publicado en 2015

Altered intrinsic neuronal excitability and reduced Na+ currents in a mouse model of Alzheimer's disease.

artículo científico publicado en 2011

Altered synaptic plasticity in the mossy fibre pathway of transgenic mice expressing mutant amyloid precursor protein ⬇️

artículo científico publicado el 1 de noviembre de 2010

Are stem cell-derived neural cells physiologically credible?

artículo científico publicado en 2016

Characterisation of recombinant rat TRPM2 and a TRPM2-like conductance in cultured rat striatal neurones

artículo científico publicado en 2005

Characterization of altered intrinsic excitability in hippocampal CA1 pyramidal cells of the Aβ-overproducing PDAPP mouse.

artículo científico publicado en 2013

Characterization of the human HCN1 channel and its inhibition by capsazepine.

artículo científico publicado en 2004

Cloning and functional expression of a human orthologue of rat vanilloid receptor-1.

artículo científico publicado en 2000

Cloning and functional expression of human short TRP7, a candidate protein for store-operated Ca2+ influx.

artículo científico publicado en 2002

Cloning, localisation and functional expression of a novel human, cerebellum specific, two pore domain potassium channel

artículo científico publicado en 2000

Contrasting biophysical and pharmacological properties of T-type and R-type calcium channels.

artículo científico publicado en 1997

Contribution of postsynaptic T-type calcium channels to parallel fibre-Purkinje cell synaptic responses.

artículo científico publicado en 2015

Detection of Aβ plaque-associated astrogliosis in Alzheimer's disease brain by spectroscopic imaging and immunohistochemistry

artículo científico publicado en 2017

Differential aging-related changes in neurophysiology and gene expression in IB4-positive and IB4-negative nociceptive neurons.

artículo científico publicado en 2018

Discovery of SB-705498: a potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development

artículo científico publicado en 2006

Discovery of small molecule antagonists of TRPV1.

artículo científico publicado en 2004

Disrupted hippocampal sharp-wave ripple-associated spike dynamics in a transgenic mouse model of dementia

artículo científico publicado en 2014

Disrupted in schizophrenia 1 and synaptic function in the mammalian central nervous system.

artículo científico

Distinctive pharmacology and kinetics of cloned neuronal Ca2+ channels and their possible counterparts in mammalian CNS neurons.

artículo científico publicado en 1993

Distribution and expression of TREK-1, a two-pore-domain potassium channel, in the adult rat CNS

scientific journal article

Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1)

artículo científico publicado en 2005

Electrical and Network Neuronal Properties Are Preferentially Disrupted in Dorsal, But Not Ventral, Medial Entorhinal Cortex in a Mouse Model of Tauopathy.

artículo científico publicado en 2016

Electrophysiological characterisation of the human N-type Ca2+ channel II: activation and inactivation by physiological patterns of activity.

artículo científico publicado en 1998

Electrophysiological properties of the human N-type Ca2+ channel: I. Channel gating in Ca2+, Ba2+ and Sr2+ containing solutions.

artículo científico publicado en 1997

Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1.

artículo científico publicado en 2002

Forced cell cycle exit and modulation of GABAA, CREB, and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons.

artículo científico publicado en 2015

Frequency‐Dependent Actions of Benzodiazepines on GABAA Receptors in Cultured Murine Cerebellar Granule Cells ⬇️

artículo científico publicado el 1 de septiembre de 1997

Functional characterisation of human TASK-3, an acid-sensitive two-pore domain potassium channel

artículo científico publicado en 2001

Functional properties and pharmacological inhibition of ASIC channels in the human SJ-RH30 skeletal muscle cell line.

artículo científico publicado en 2004

Functionalized α-Helical Peptide Hydrogels for Neural Tissue Engineering

artículo científico publicado en 2015

Gabapentin fails to alter P/Q-type Ca2+ channel-mediated synaptic transmission in the hippocampus in vitro.

artículo científico publicado en 2005

Hippocampal circuit dysfunction in the Tc1 mouse model of Down syndrome

artículo científico publicado en 2015

Hippocampal neurophysiology is modified by a disease-associated C-terminal fragment of tau protein.

artículo científico publicado en 2017

Human primary astrocytes increase basal fatty acid oxidation following recurrent low glucose to maintain intracellular nucleotide levels

Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist.

artículo científico publicado en 2004

Improving and accelerating the differentiation and functional maturation of human stem cell-derived neurons: role of extracellular calcium and GABA.

artículo científico publicado en 2016

In vitro characterization of cell-level neurophysiological diversity in the rostral nucleus reuniens of adult mice.

artículo científico publicado en 2017

Inhibition of Ih reduces epileptiform activity in rodent hippocampal slices.

artículo científico publicado en 2006

Inhibition of TRPM2 channels by the antifungal agents clotrimazole and econazole.

artículo científico publicado en 2004

Inhibition of human N-type voltage-gated Ca2+ channels by the neuroprotective agent BW619C89 ⬇️

artículo científico publicado el 1 de noviembre de 1997

Inhibition of post-synaptic Kv7/KCNQ/M channels facilitates long-term potentiation in the hippocampus

artículo científico publicado en 2012

Initiation and slow propagation of epileptiform activity from ventral to dorsal medial entorhinal cortex is constrained by an inhibitory gradient.

artículo científico publicado en 2018

Intrinsic excitability changes induced by acute treatment of hippocampal CA1 pyramidal neurons with exogenous amyloid β peptide

artículo científico publicado en 2015

Introduction to the special issue on Alzheimer's disease.

artículo científico publicado en 2010

KCNQ/Kv7 channel regulation of hippocampal gamma-frequency firing in the absence of synaptic transmission.

artículo científico publicado en 2006

Kinetic modification of the alpha(1I) subunit-mediated T-type Ca(2+) channel by a human neuronal Ca(2+) channel gamma subunit.

artículo científico publicado en 2001

Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons

artículo científico publicado en 2018

Long-term culture of pluripotent stem-cell-derived human neurons on diamond--A substrate for neurodegeneration research and therapy

artículo científico publicado en 2015

Low concentrations of the solvent dimethyl sulphoxide alter intrinsic excitability properties of cortical and hippocampal pyramidal cells

artículo científico publicado en 2014

Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices expressing a C-terminal truncated GABA(B2) receptor subunit

artículo científico publicado en 2005

Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices of GABAB1 receptor subunit knockout mice.

artículo científico publicado en 2003

Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease

artículo científico publicado en 2017

Modulation of hippocampal excitability by 5-HT4 receptor agonists persists in a transgenic model of Alzheimer's disease.

artículo científico publicado en 2004

Modulation of recombinant T-type Ca2+ channels by hypoxia and glutathione.

artículo científico publicado en 2000

Modulation of the deactivation kinetics of a recombinant rat T-type Ca(2+) channel by prior inactivation.

artículo científico publicado en 2000

Muscarinic Receptor-Dependent Long Term Depression in the Perirhinal Cortex and Recognition Memory are Impaired in the rTg4510 Mouse Model of Tauopathy.

artículo científico publicado en 2018

Na(v)1.5 sodium channels in a human microglial cell line.

artículo científico publicado en 2009

Neurophysiological modification of CA1 pyramidal neurons in a transgenic mouse expressing a truncated form of disrupted-in-schizophrenia 1

artículo científico publicado en 2014

Neuroprotective actions in vivo and electrophysiological actions in vitro of 202W92.

artículo científico publicado en 2001

Old and new pharmacology: positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor by the 5-hydroxytryptamine(2B/C) receptor antagonist SB-206553 (3,5-dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']di pyrrole-1(2H)-carboxamide)

artículo científico publicado en 2009

Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia.

artículo científico publicado en 2016

Potent inhibition of a recombinant low voltage-activated Ca(2+) channel by SB-209712.

artículo científico publicado en 2000

Properties of GABA(A) receptors in cultured rat oligodendrocyte progenitor cells.

artículo científico publicado en 1998

Recent advances in the molecular understanding of voltage-gated Ca2+ channels.

artículo científico publicado en 1999

Receptor-mediated suppression of potassium currents requires colocalization within lipid rafts

scientific journal article

Secretions from placenta, after hypoxia/reoxygenation, can damage developing neurones of brain under experimental conditions.

artículo científico publicado en 2014

Sex-associated differences in excitability within the bed nucleus of the stria terminalis are reflective of cell-type

scientific article published on 19 December 2018

Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness

artículo científico publicado en 2011

Somato-synaptic variation of GABAA receptors in cultured murine cerebellar granule cells: investigation of the role of the α6 subunit

artículo científico publicado en 2000

Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release

artículo científico publicado en 2016

Synaptic activation of GABA(B) receptors regulates neuronal network activity and entrainment.

artículo científico publicado en 2007

Synaptic activation of mGluR1 generates persistent depression of a fast after-depolarizing potential in CA3 pyramidal neurons.

artículo científico publicado en 2011

Synaptic transmission and synchronous activity is disrupted in hippocampal slices taken from aged TAS10 mice

artículo científico publicado en 2005

TRPM2 is elevated in the tMCAO stroke model, transcriptionally regulated, and functionally expressed in C13 microglia.

artículo científico publicado en 2006

TRPV1 antagonist, SB-366791, inhibits glutamatergic synaptic transmission in rat spinal dorsal horn following peripheral inflammation

article

TRPV3 is a temperature-sensitive vanilloid receptor-like protein.

artículo científico publicado en 2002

The GABAB2 subunit is critical for the trafficking and function of native GABAB receptors

artículo científico publicado en 2004

The diversity in the vanilloid (TRPV) receptor family of ion channels

artículo científico publicado en 2002

The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1)

artículo científico publicado en 2000

The induction of long-term plasticity of non-synaptic, synchronized activity by the activation of group I mGluRs.

artículo científico publicado en 2008

The metabotropic glutamate receptor 7 allosteric modulator AMN082: a monoaminergic agent in disguise?

artículo científico publicado en 2011

The molecular basis of voltage-gated Ca2+ channel diversity: is it time for T?

artículo científico publicado en 1998

The neuroprotective agent sipatrigine (BW619C89) potently inhibits the human tandem pore-domain K(+) channels TREK-1 and TRAAK.

artículo científico publicado en 2001

The taurine uptake inhibitor guanidinoethyl sulphonate is an agonist at γ-aminobutyric acidA receptors in cultured murine cerebellar granule cells

scientific article published on 01 May 2000

Tonic benzodiazepine-sensitive GABAergic inhibition in cultured rodent cerebellar granule cells

artículo científico publicado en 2000

Transgenic mice over-expressing human beta-amyloid have functional nicotinic alpha 7 receptors.

artículo científico publicado en 2005

Vanilloid and TRP channels: a family of lipid-gated cation channels.

artículo científico publicado en 2002

Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

artículo científico publicado en 2000

Voltage- and Temperature-Dependent Allosteric Modulation of α7 Nicotinic Receptors by PNU120596 ⬇️

artículo científico publicado el 27 de diciembre de 2011

Voltage- and ligand-gated ion channels in floor plate neuroepithelia of the rat.

artículo científico publicado en 1998

Voltage- and temperature-dependent gating of heterologously expressed channelrhodopsin-2

artículo científico publicado en 2010

Voltage- and time-dependent properties of the recombinant rat vanilloid receptor (rVR1)

artículo científico publicado en 2000

Voltage-dependent deactivation and desensitization of GABA responses in cultured murine cerebellar granule cells.

artículo científico publicado en 1998

mRNA distribution analysis of human TRPC family in CNS and peripheral tissues.

artículo científico publicado en 2002

Lista de obras de Andrew Randall

4-dimensional functional profiling in the convulsant-treated larval zebrafish brain.

A New Player in the “Synaptopathy” of Alzheimer’s Disease – Arc/Arg 3.1 ⬇️

A comparison of paired-pulse facilitation of AMPA and NMDA receptor-mediated excitatory postsynaptic currents in the hippocampus

A monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons

A unified model of CA1/3 pyramidal cells: an investigation into excitability.

AICA riboside both activates AMP-activated protein kinase and competes with adenosine for the nucleoside transporter in the CA1 region of the rat hippocampus.

Actions of sipatrigine, 202W92 and lamotrigine on R-type and T-type Ca2+ channel currents

Activity-dependent depression of the spike after-depolarization generates long-lasting intrinsic plasticity in hippocampal CA3 pyramidal neurons.

Altered Intrinsic Pyramidal Neuron Properties and Pathway-Specific Synaptic Dysfunction Underlie Aberrant Hippocampal Network Function in a Mouse Model of Tauopathy.

Altered Synapse Stability in the Early Stages of Tauopathy

Altered functional brain network connectivity and glutamate system function in transgenic mice expressing truncated Disrupted-in-Schizophrenia 1

Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice

Altered intrinsic neuronal excitability and reduced Na+ currents in a mouse model of Alzheimer's disease.

Altered synaptic plasticity in the mossy fibre pathway of transgenic mice expressing mutant amyloid precursor protein ⬇️

Are stem cell-derived neural cells physiologically credible?

Characterisation of recombinant rat TRPM2 and a TRPM2-like conductance in cultured rat striatal neurones

Characterization of altered intrinsic excitability in hippocampal CA1 pyramidal cells of the Aβ-overproducing PDAPP mouse.

Characterization of the human HCN1 channel and its inhibition by capsazepine.

Cloning and functional expression of a human orthologue of rat vanilloid receptor-1.

Cloning and functional expression of human short TRP7, a candidate protein for store-operated Ca2+ influx.

Cloning, localisation and functional expression of a novel human, cerebellum specific, two pore domain potassium channel

Contrasting biophysical and pharmacological properties of T-type and R-type calcium channels.

Contribution of postsynaptic T-type calcium channels to parallel fibre-Purkinje cell synaptic responses.

Detection of Aβ plaque-associated astrogliosis in Alzheimer's disease brain by spectroscopic imaging and immunohistochemistry

Differential aging-related changes in neurophysiology and gene expression in IB4-positive and IB4-negative nociceptive neurons.

Discovery of SB-705498: a potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development

Discovery of small molecule antagonists of TRPV1.

Disrupted hippocampal sharp-wave ripple-associated spike dynamics in a transgenic mouse model of dementia

Disrupted in schizophrenia 1 and synaptic function in the mammalian central nervous system.

Distinctive pharmacology and kinetics of cloned neuronal Ca2+ channels and their possible counterparts in mammalian CNS neurons.

Distribution and expression of TREK-1, a two-pore-domain potassium channel, in the adult rat CNS

Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1)

Electrical and Network Neuronal Properties Are Preferentially Disrupted in Dorsal, But Not Ventral, Medial Entorhinal Cortex in a Mouse Model of Tauopathy.

Electrophysiological characterisation of the human N-type Ca2+ channel II: activation and inactivation by physiological patterns of activity.

Electrophysiological properties of the human N-type Ca2+ channel: I. Channel gating in Ca2+, Ba2+ and Sr2+ containing solutions.

Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1.

Forced cell cycle exit and modulation of GABAA, CREB, and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons.

Frequency‐Dependent Actions of Benzodiazepines on GABAA Receptors in Cultured Murine Cerebellar Granule Cells ⬇️

Functional characterisation of human TASK-3, an acid-sensitive two-pore domain potassium channel

Functional properties and pharmacological inhibition of ASIC channels in the human SJ-RH30 skeletal muscle cell line.

Functionalized α-Helical Peptide Hydrogels for Neural Tissue Engineering

Gabapentin fails to alter P/Q-type Ca2+ channel-mediated synaptic transmission in the hippocampus in vitro.

Hippocampal circuit dysfunction in the Tc1 mouse model of Down syndrome

Hippocampal neurophysiology is modified by a disease-associated C-terminal fragment of tau protein.

Human primary astrocytes increase basal fatty acid oxidation following recurrent low glucose to maintain intracellular nucleotide levels

Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist.

Improving and accelerating the differentiation and functional maturation of human stem cell-derived neurons: role of extracellular calcium and GABA.

In vitro characterization of cell-level neurophysiological diversity in the rostral nucleus reuniens of adult mice.

Inhibition of Ih reduces epileptiform activity in rodent hippocampal slices.

Inhibition of TRPM2 channels by the antifungal agents clotrimazole and econazole.

Inhibition of human N-type voltage-gated Ca2+ channels by the neuroprotective agent BW619C89 ⬇️

Inhibition of post-synaptic Kv7/KCNQ/M channels facilitates long-term potentiation in the hippocampus

Initiation and slow propagation of epileptiform activity from ventral to dorsal medial entorhinal cortex is constrained by an inhibitory gradient.

Intrinsic excitability changes induced by acute treatment of hippocampal CA1 pyramidal neurons with exogenous amyloid β peptide

Introduction to the special issue on Alzheimer's disease.

KCNQ/Kv7 channel regulation of hippocampal gamma-frequency firing in the absence of synaptic transmission.

Kinetic modification of the alpha(1I) subunit-mediated T-type Ca(2+) channel by a human neuronal Ca(2+) channel gamma subunit.

Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons

Long-term culture of pluripotent stem-cell-derived human neurons on diamond--A substrate for neurodegeneration research and therapy

Low concentrations of the solvent dimethyl sulphoxide alter intrinsic excitability properties of cortical and hippocampal pyramidal cells

Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices expressing a C-terminal truncated GABA(B2) receptor subunit

Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices of GABAB1 receptor subunit knockout mice.

Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease

Modulation of hippocampal excitability by 5-HT4 receptor agonists persists in a transgenic model of Alzheimer's disease.

Modulation of recombinant T-type Ca2+ channels by hypoxia and glutathione.

Modulation of the deactivation kinetics of a recombinant rat T-type Ca(2+) channel by prior inactivation.

Muscarinic Receptor-Dependent Long Term Depression in the Perirhinal Cortex and Recognition Memory are Impaired in the rTg4510 Mouse Model of Tauopathy.

Na(v)1.5 sodium channels in a human microglial cell line.

Neurophysiological modification of CA1 pyramidal neurons in a transgenic mouse expressing a truncated form of disrupted-in-schizophrenia 1

Neuroprotective actions in vivo and electrophysiological actions in vitro of 202W92.

Old and new pharmacology: positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor by the 5-hydroxytryptamine(2B/C) receptor antagonist SB-206553 (3,5-dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']di pyrrole-1(2H)-carboxamide)

Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia.

Potent inhibition of a recombinant low voltage-activated Ca(2+) channel by SB-209712.

Properties of GABA(A) receptors in cultured rat oligodendrocyte progenitor cells.

Recent advances in the molecular understanding of voltage-gated Ca2+ channels.

Receptor-mediated suppression of potassium currents requires colocalization within lipid rafts

Secretions from placenta, after hypoxia/reoxygenation, can damage developing neurones of brain under experimental conditions.

Sex-associated differences in excitability within the bed nucleus of the stria terminalis are reflective of cell-type

Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness