Lista de obras - Jana Selent - Dominio Público Uruguay

A dynamic view of molecular switch behavior at serotonin receptors: implications for functional selectivity

artículo científico publicado en 2014

A gain-of-function SNP in TRPC4 cation channel protects against myocardial infarction

artículo científico publicado en 2011

A novel multilevel statistical method for the study of the relationships between multireceptorial binding affinity profiles and in vivo endpoints

artículo científico publicado en 2009

Application of BRET for studying G protein-coupled receptors.

artículo científico publicado en 2014

C-edge loops of arrestin function as a membrane anchor

artículo científico publicado en 2017

Can molecular dynamics simulations improve the structural accuracy and virtual screening performance of GPCR models?

artículo científico publicado en 2021

Computational methods for studying G protein-coupled receptors (GPCRs).

artículo científico publicado en 2015

Crosstalk within GPCR heteromers in schizophrenia and Parkinson's disease: physical or just functional?

artículo científico publicado en 2012

Detection of new biased agonists for the serotonin 5-HT2A receptor: modeling and experimental validation.

artículo científico publicado en 2015

Distinct phosphorylation sites in a prototypical GPCR differently orchestrate β-arrestin interaction, trafficking, and signaling

scientific article published on 11 September 2020

Dopamine D Receptor Agonist Binding Kinetics-Role of a Conserved Serine Residue

scientific article published in 2021

Drugging specific conformational states of GPCRs: challenges and opportunities for computational chemistry

artículo científico publicado en 2016

Electronic sculpting of ligand-GPCR subtype selectivity: the case of angiotensin II.

artículo científico publicado en 2014

Enantiomeric N-methyl-4-piperidyl benzilates as muscarinic receptor ligands: Radioligand binding studies and docking studies to models of the three muscarinic receptors M1, M2 and M3.

artículo científico publicado en 2005

Equine estrogens impair nitric oxide production and endothelial nitric oxide synthase transcription in human endothelial cells compared with the natural 17{beta}-estradiol

artículo científico publicado en 2010

Fractal dimension as a measure of surface roughness of G protein-coupled receptors: implications for structure and function

artículo científico publicado en 2012

GPCRmd uncovers the dynamics of the 3D-GPCRome

scientific article published on 13 July 2020

In silico Exploration of the Conformational Universe of GPCRs.

artículo científico publicado en 2016

Induced effects of sodium ions on dopaminergic G-protein coupled receptors

artículo científico publicado en 2010

Ligand with Two Modes of Interaction with the Dopamine D2 Receptor-An Induced-Fit Mechanism of Insurmountable Antagonism

scientific article published on 15 September 2020

MEMBPLUGIN: studying membrane complexity in VMD.

artículo científico publicado en 2014

Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory.

artículo científico publicado en 2015

Membrane cholesterol access into a G-protein-coupled receptor

artículo científico publicado en 2017

Membrane cholesterol effect on the 5-HT2A receptor: Insights into the lipid-induced modulation of an antipsychotic drug target.

artículo científico publicado en 2017

Membrane omega-3 fatty acids modulate the oligomerisation kinetics of adenosine A2A and dopamine D2 receptors

artículo científico publicado en 2016

Membrane-sensitive conformational states of helix 8 in the metabotropic Glu2 receptor, a class C GPCR

artículo científico publicado en 2012

Modeling Complexes of Transmembrane Proteins: Systematic Analysis of ProteinProtein Docking Tools

artículo científico publicado en 2013

Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors

artículo científico publicado en 2024

Multi-Component Protein - Protein Docking Based Protocol with External Scoring for Modeling Dimers of G Protein-Coupled Receptors

artículo científico publicado en 2015

Multi-receptor binding profile of clozapine and olanzapine: a structural study based on the new beta2 adrenergic receptor template

artículo científico publicado en 2008

Novel insights into biased agonism at G protein-coupled receptors and their potential for drug design

artículo científico publicado en 2013

Novel insights on the structural determinants of clozapine and olanzapine multi-target binding profiles

scholarly article by Jana Selent et al published April 2014 in European Journal of Medicinal Chemistry

Palmitoylation of cysteine 415 of CB1 receptor affects ligand-stimulated internalization and selective interaction with membrane cholesterol and caveolin 1.

artículo científico publicado en 2017

Progress in the structural prediction of G protein-coupled receptors: D3 receptor in complex with eticlopride

Publisher Correction: GPCRmd uncovers the dynamics of the 3D-GPCRome

scientific article published on 23 July 2020

Rational design of the survivin/CDK4 complex by combining protein-protein docking and molecular dynamics simulations

artículo científico publicado en 2012

Role of palmitoylation of cysteine 415 in functional coupling CB1 receptor to Gαi2 protein

artículo científico

Selective inhibition of the collagenase activity of cathepsin K

scientific article published on 10 April 2007

Sharing Data from Molecular Simulations

scientific article published on 11 October 2019

Simulating G protein-coupled receptors in native-like membranes: from monomers to oligomers

artículo científico publicado en 2013

Structure-based molecular modeling approaches to GPCR oligomerization

artículo científico publicado en 2013

Synthesis, 3D-QSAR, and structural modeling of benzolactam derivatives with binding affinity for the D(2) and D(3) receptors

artículo científico publicado en 2010

Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands

artículo científico publicado en 2009

Synthesis, binding affinity, and molecular docking analysis of new benzofuranone derivatives as potential antipsychotics

artículo científico publicado en 2008

Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists

artículo científico publicado en 2018

Lista de obras de Jana Selent

A dynamic view of molecular switch behavior at serotonin receptors: implications for functional selectivity

A gain-of-function SNP in TRPC4 cation channel protects against myocardial infarction

A novel multilevel statistical method for the study of the relationships between multireceptorial binding affinity profiles and in vivo endpoints

Application of BRET for studying G protein-coupled receptors.

C-edge loops of arrestin function as a membrane anchor

Can molecular dynamics simulations improve the structural accuracy and virtual screening performance of GPCR models?

Computational methods for studying G protein-coupled receptors (GPCRs).

Crosstalk within GPCR heteromers in schizophrenia and Parkinson's disease: physical or just functional?

Detection of new biased agonists for the serotonin 5-HT2A receptor: modeling and experimental validation.

Distinct phosphorylation sites in a prototypical GPCR differently orchestrate β-arrestin interaction, trafficking, and signaling

Dopamine D Receptor Agonist Binding Kinetics-Role of a Conserved Serine Residue

Drugging specific conformational states of GPCRs: challenges and opportunities for computational chemistry

Electronic sculpting of ligand-GPCR subtype selectivity: the case of angiotensin II.

Enantiomeric N-methyl-4-piperidyl benzilates as muscarinic receptor ligands: Radioligand binding studies and docking studies to models of the three muscarinic receptors M1, M2 and M3.

Equine estrogens impair nitric oxide production and endothelial nitric oxide synthase transcription in human endothelial cells compared with the natural 17{beta}-estradiol

Fractal dimension as a measure of surface roughness of G protein-coupled receptors: implications for structure and function

GPCRmd uncovers the dynamics of the 3D-GPCRome

In silico Exploration of the Conformational Universe of GPCRs.

Induced effects of sodium ions on dopaminergic G-protein coupled receptors

Ligand with Two Modes of Interaction with the Dopamine D2 Receptor-An Induced-Fit Mechanism of Insurmountable Antagonism

MEMBPLUGIN: studying membrane complexity in VMD.

Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory.

Membrane cholesterol access into a G-protein-coupled receptor

Membrane cholesterol effect on the 5-HT2A receptor: Insights into the lipid-induced modulation of an antipsychotic drug target.

Membrane omega-3 fatty acids modulate the oligomerisation kinetics of adenosine A2A and dopamine D2 receptors

Membrane-sensitive conformational states of helix 8 in the metabotropic Glu2 receptor, a class C GPCR

Modeling Complexes of Transmembrane Proteins: Systematic Analysis of ProteinProtein Docking Tools

Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors

Multi-Component Protein - Protein Docking Based Protocol with External Scoring for Modeling Dimers of G Protein-Coupled Receptors

Multi-receptor binding profile of clozapine and olanzapine: a structural study based on the new beta2 adrenergic receptor template

Novel insights into biased agonism at G protein-coupled receptors and their potential for drug design

Novel insights on the structural determinants of clozapine and olanzapine multi-target binding profiles

Palmitoylation of cysteine 415 of CB1 receptor affects ligand-stimulated internalization and selective interaction with membrane cholesterol and caveolin 1.

Progress in the structural prediction of G protein-coupled receptors: D3 receptor in complex with eticlopride

Publisher Correction: GPCRmd uncovers the dynamics of the 3D-GPCRome

Rational design of the survivin/CDK4 complex by combining protein-protein docking and molecular dynamics simulations

Role of palmitoylation of cysteine 415 in functional coupling CB1 receptor to Gαi2 protein

Selective inhibition of the collagenase activity of cathepsin K

Sharing Data from Molecular Simulations

Simulating G protein-coupled receptors in native-like membranes: from monomers to oligomers

Structure-based molecular modeling approaches to GPCR oligomerization

Synthesis, 3D-QSAR, and structural modeling of benzolactam derivatives with binding affinity for the D(2) and D(3) receptors

Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands

Synthesis, binding affinity, and molecular docking analysis of new benzofuranone derivatives as potential antipsychotics

Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists

Tungstate activates BK channels in a β subunit- and Mg2+-dependent manner: relevance for arterial vasodilatation