Lista de obras - Santina Bruzzone - Dominio Público Uruguay

A critical role of autophagy in antileukemia/lymphoma effects of APO866, an inhibitor of NAD biosynthesis

artículo científico publicado en 2014

ADP-ribosyl cyclases generate two unusual adenine homodinucleotides with cytotoxic activity on mammalian cells

artículo científico publicado en 2005

Abscisic Acid Stimulates Glucagon-Like Peptide-1 Secretion from L-Cells and Its Oral Administration Increases Plasma Glucagon-Like Peptide-1 Levels in Rats

artículo científico publicado en 2015

Abscisic Acid: A Novel Nutraceutical for Glycemic Control

artículo científico publicado en 2017

Abscisic acid activates the murine microglial cell line N9 through the second messenger cyclic ADP-ribose

artículo científico publicado en 2009

Abscisic acid enhances glucose disposal and induces brown fat activity in adipocytes in vitro and in vivo

artículo científico publicado en 2016

Abscisic acid is an endogenous cytokine in human granulocytes with cyclic ADP-ribose as second messenger

artículo científico publicado en 2007

Abscisic acid is an endogenous stimulator of insulin release from human pancreatic islets with cyclic ADP ribose as second messenger

artículo científico publicado en 2008

Abscisic acid released by human monocytes activates monocytes and vascular smooth muscle cell responses involved in atherogenesis

artículo científico publicado en 2009

Abscisic acid signaling through cyclic ADP-ribose in hydroid regeneration

artículo científico publicado en 2004

Abscisic acid stimulates the release of insulin and of GLP-1 in the rat perfused pancreas and intestine

artículo científico publicado en 2018

Adenylic dinucleotides produced by CD38 are negative endogenous modulators of platelet aggregation.

artículo científico publicado en 2008

Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model

artículo científico publicado en 2015

Autocrine abscisic acid mediates the UV-B-induced inflammatory response in human granulocytes and keratinocytes

artículo científico publicado en 2012

Autocrine abscisic acid plays a key role in quartz-induced macrophage activation

artículo científico publicado en 2011

Autocrine and paracrine calcium signaling by the CD38/NAD+/cyclic ADP-ribose system

artículo científico publicado en 2004

Binding of abscisic acid to human LANCL2 ⬇️

artículo científico publicado el 20 de octubre de 2011

CD73 Protein as a Source of Extracellular Precursors for Sustained NAD+ Biosynthesis in FK866-treated Tumor Cells ⬇️

artículo científico publicado el 23 de julio de 2013

Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE.

artículo científico publicado en 2009

Concentrative influx of functionally active cyclic ADP-ribose in dimethyl sulfoxide-differentiated HL-60 cells

artículo científico publicado en 2004

Concentrative uptake of cyclic ADP-ribose generated by BST-1+ stroma stimulates proliferation of human hematopoietic progenitors

artículo científico publicado en 2004

Cyclic ADP-ribose generation by CD38 improves human hemopoietic stem cell engraftment into NOD/SCID mice

artículo científico publicado en 2002

Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated activation of murine N9 microglial cell line

artículo científico publicado en 2006

Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated proliferation of human peripheral blood mononuclear cells

artículo científico publicado en 2003

Cycling Assay for Determining Intracellular Cyclic ADP-Ribose Levels ⬇️

artículo científico publicado el 1 de junio de 2013

Diadenosine homodinucleotide products of ADP-ribosyl cyclases behave as modulators of the purinergic receptor P2X7.

artículo científico publicado en 2010

Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules

artículo científico publicado en 2019

Discovery of novel and selective SIRT6 inhibitors

artículo científico publicado en 2014

Emerging functions of extracellular pyridine nucleotides

artículo científico publicado en 2006

Equilibrative and concentrative nucleoside transporters mediate influx of extracellular cyclic ADP-ribose into 3T3 murine fibroblasts

artículo científico publicado en 2002

Extracellular NAD+ is an agonist of the human P2Y11 purinergic receptor in human granulocytes

artículo científico publicado en 2006

Extracellular NAD+ regulates intracellular calcium levels and induces activation of human granulocytes

artículo científico publicado en 2006

Fluridone as a new anti-inflammatory drug

artículo científico publicado en 2013

G-protein coupling and nuclear translocation of the human abscisic acid receptor LANCL2

artículo científico publicado en 2016

Glutamate-mediated overexpression of CD38 in astrocytes cultured with neurones

artículo científico publicado en 2004

Inhibition of nicotinamide phosphoribosyltransferase reduces neutrophil-mediated injury in myocardial infarction

artículo científico publicado en 2012

LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells

artículo científico publicado en 2009

Mesenchymal Stem Cells Shape Microglia Effector Functions Through the Release of CX3CL1

article by Debora Giunti et al published 20 August 2012 in Stem Cells

Mitochondrial Dysfunction Induced by a Cytotoxic Adenine Dinucleotide Produced by ADP-ribosyl Cyclases from cADPR

scientific article published in Journal of Biological Chemistry

NAADP+ is an agonist of the human P2Y11 purinergic receptor

artículo científico publicado en 2007

NAADP+ synthesis from cADPRP and nicotinic acid by ADP-ribosyl cyclases

artículo científico publicado en 2006

NAD+ levels control Ca2+ store replenishment and mitogen-induced increase of cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 channel gating in human T lymphocytes

artículo científico publicado en 2012

Nicotinamide phosphoribosyltransferase as a target in inflammation- related disorders

artículo científico publicado en 2013

Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice

artículo científico publicado en 2013

P2X7-mediated increased intracellular calcium causes functional derangement in Schwann cells from rats with CMT1A neuropathy

artículo científico publicado en 2009

Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model

artículo científico publicado en 2017

Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells

artículo científico publicado en 2010

Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics

Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin

artículo científico publicado en 2017

Regulation of Human Mesenchymal Stem Cell Functions by an Autocrine Loop Involving NAD+ Release and P2Y11-Mediated Signaling

scholarly article by Floriana Fruscione et al published July 2011 in Stem Cells and Development

Rejuvenating sirtuins: the rise of a new family of cancer drug targets

artículo científico publicado en 2013

SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects.

artículo científico publicado en 2017

Selectivity hot-spots of sirtuin catalytic cores

artículo científico publicado en 2015

Spatio-temporal propagation of Ca2+ signals by cyclic ADP-ribose in 3T3 cells stimulated via purinergic P2Y receptors ⬇️

artículo científico publicado el 17 de noviembre de 2003

Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells

artículo científico publicado en 2011

The Diadenosine Homodinucleotide P18 Improves In Vitro Myelination in Experimental Charcot‐Marie‐Tooth Type 1A ⬇️

artículo científico publicado el 1 de enero de 2014

The NAD+-dependent Histone Deacetylase SIRT6 Promotes Cytokine Production and Migration in Pancreatic Cancer Cells by Regulating Ca2+ Responses ⬇️

artículo científico publicado el 18 de octubre de 2012

The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism

artículo científico publicado en 2012

The human immunodeficiency virus-1 protein Tat and its discrete fragments evoke selective release of acetylcholine from human and rat cerebrocortical terminals through species-specific mechanisms.

artículo científico publicado en 2003

The plant hormone abscisic acid increases in human plasma after hyperglycemia and stimulates glucose consumption by adipocytes and myoblasts ⬇️

artículo científico publicado el 10 de noviembre de 2011

The plant hormone abscisic acid stimulates the proliferation of human hemopoietic progenitors through the second messenger cyclic ADP-ribose.

artículo científico publicado en 2009

Tolerability and efficacy study of P2X7 inhibition in experimental Charcot-Marie-Tooth type 1A (CMT1A) neuropathy.

artículo científico publicado en 2016

Lista de obras de Santina Bruzzone

A critical role of autophagy in antileukemia/lymphoma effects of APO866, an inhibitor of NAD biosynthesis

ADP-ribosyl cyclases generate two unusual adenine homodinucleotides with cytotoxic activity on mammalian cells

Abscisic Acid Stimulates Glucagon-Like Peptide-1 Secretion from L-Cells and Its Oral Administration Increases Plasma Glucagon-Like Peptide-1 Levels in Rats

Abscisic Acid: A Novel Nutraceutical for Glycemic Control

Abscisic acid activates the murine microglial cell line N9 through the second messenger cyclic ADP-ribose

Abscisic acid enhances glucose disposal and induces brown fat activity in adipocytes in vitro and in vivo

Abscisic acid is an endogenous cytokine in human granulocytes with cyclic ADP-ribose as second messenger

Abscisic acid is an endogenous stimulator of insulin release from human pancreatic islets with cyclic ADP ribose as second messenger

Abscisic acid released by human monocytes activates monocytes and vascular smooth muscle cell responses involved in atherogenesis

Abscisic acid signaling through cyclic ADP-ribose in hydroid regeneration

Abscisic acid stimulates the release of insulin and of GLP-1 in the rat perfused pancreas and intestine

Adenylic dinucleotides produced by CD38 are negative endogenous modulators of platelet aggregation.

Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model

Autocrine abscisic acid mediates the UV-B-induced inflammatory response in human granulocytes and keratinocytes

Autocrine abscisic acid plays a key role in quartz-induced macrophage activation

Autocrine and paracrine calcium signaling by the CD38/NAD+/cyclic ADP-ribose system

Binding of abscisic acid to human LANCL2 ⬇️

CD73 Protein as a Source of Extracellular Precursors for Sustained NAD+ Biosynthesis in FK866-treated Tumor Cells ⬇️

Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE.

Concentrative influx of functionally active cyclic ADP-ribose in dimethyl sulfoxide-differentiated HL-60 cells

Concentrative uptake of cyclic ADP-ribose generated by BST-1+ stroma stimulates proliferation of human hematopoietic progenitors

Cyclic ADP-ribose generation by CD38 improves human hemopoietic stem cell engraftment into NOD/SCID mice

Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated activation of murine N9 microglial cell line

Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated proliferation of human peripheral blood mononuclear cells

Cycling Assay for Determining Intracellular Cyclic ADP-Ribose Levels ⬇️

Diadenosine homodinucleotide products of ADP-ribosyl cyclases behave as modulators of the purinergic receptor P2X7.

Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules

Discovery of novel and selective SIRT6 inhibitors

Emerging functions of extracellular pyridine nucleotides

Equilibrative and concentrative nucleoside transporters mediate influx of extracellular cyclic ADP-ribose into 3T3 murine fibroblasts

Extracellular NAD+ is an agonist of the human P2Y11 purinergic receptor in human granulocytes

Extracellular NAD+ regulates intracellular calcium levels and induces activation of human granulocytes

Fluridone as a new anti-inflammatory drug

G-protein coupling and nuclear translocation of the human abscisic acid receptor LANCL2

Glutamate-mediated overexpression of CD38 in astrocytes cultured with neurones

Inhibition of nicotinamide phosphoribosyltransferase reduces neutrophil-mediated injury in myocardial infarction

LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells

Mesenchymal Stem Cells Shape Microglia Effector Functions Through the Release of CX3CL1

Mitochondrial Dysfunction Induced by a Cytotoxic Adenine Dinucleotide Produced by ADP-ribosyl Cyclases from cADPR

NAADP+ is an agonist of the human P2Y11 purinergic receptor

NAADP+ synthesis from cADPRP and nicotinic acid by ADP-ribosyl cyclases

NAD+ levels control Ca2+ store replenishment and mitogen-induced increase of cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 channel gating in human T lymphocytes

Nicotinamide phosphoribosyltransferase as a target in inflammation- related disorders

Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice

P2X7-mediated increased intracellular calcium causes functional derangement in Schwann cells from rats with CMT1A neuropathy

Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model

Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells

Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics

Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin

Regulation of Human Mesenchymal Stem Cell Functions by an Autocrine Loop Involving NAD+ Release and P2Y11-Mediated Signaling

Rejuvenating sirtuins: the rise of a new family of cancer drug targets

SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects.

Selectivity hot-spots of sirtuin catalytic cores

Spatio-temporal propagation of Ca2+ signals by cyclic ADP-ribose in 3T3 cells stimulated via purinergic P2Y receptors ⬇️

Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells

The Diadenosine Homodinucleotide P18 Improves In Vitro Myelination in Experimental Charcot‐Marie‐Tooth Type 1A ⬇️

The NAD+-dependent Histone Deacetylase SIRT6 Promotes Cytokine Production and Migration in Pancreatic Cancer Cells by Regulating Ca2+ Responses ⬇️

The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism

The human immunodeficiency virus-1 protein Tat and its discrete fragments evoke selective release of acetylcholine from human and rat cerebrocortical terminals through species-specific mechanisms.

The plant hormone abscisic acid increases in human plasma after hyperglycemia and stimulates glucose consumption by adipocytes and myoblasts ⬇️

The plant hormone abscisic acid stimulates the proliferation of human hemopoietic progenitors through the second messenger cyclic ADP-ribose.

Tolerability and efficacy study of P2X7 inhibition in experimental Charcot-Marie-Tooth type 1A (CMT1A) neuropathy.