Lista de obras - Marco Vanoni - Dominio Público Uruguay

5-fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits

artículo científico publicado en 2015

A 9359 bp fragment from the right arm ofSaccharomyces cerevisiae chromosome VII includes theFOL2 andYTA7 genes and three unknown open reading frames ⬇️

artículo científico publicado el 30 de abril de 1998

A cell sizer network involving Cln3 and Far1 controls entrance into S phase in the mitotic cycle of budding yeast.

artículo científico publicado en 2004

A comparative study of Whi5 and retinoblastoma proteins: from sequence and structure analysis to intracellular networks.

artículo científico publicado en 2013

A computer algorithm for the analysis of protein distribution in budding yeast.

artículo científico publicado en 1984

A dominant negative RAS-specific guanine nucleotide exchange factor reverses neoplastic phenotype in K-ras transformed mouse fibroblasts.

artículo científico publicado en 2000

A metabolic core model elucidates how enhanced utilization of glucose and glutamine, with enhanced glutamine-dependent lactate production, promotes cancer cell growth: The WarburQ effect

artículo científico publicado en 2017

A mouse CDC25-like product enhances the formation of the active GTP complex of human ras p21 and Saccharomyces cerevisiae RAS2 proteins

artículo científico publicado en 1992

A systems biology road map for the discovery of drugs targeting cancer cell metabolism.

artículo científico

Acquired glucose sensitivity of k-ras transformed fibroblasts.

artículo científico publicado en 2005

An acidic loop and cognate phosphorylation sites define a molecular switch that modulates ubiquitin charging activity in Cdc34-like enzymes

artículo científico publicado en 2011

Approaches to Ras signaling modulation and treatment of Ras-dependent disorders: a patent review (2007--present).

artículo científico

Biochemical and immunological characterization of the STA2-encoded extracellular glucoamylase from saccharomyces diastaticus

scientific article published on 01 July 1986

CK2 regulates in vitro the activity of the yeast cyclin-dependent kinase inhibitor Sic1

artículo científico publicado en 2005

Cancer cell growth and survival as a system-level property sustained by enhanced glycolysis and mitochondrial metabolic remodeling

artículo científico publicado en 2012

Catalytic competence of the Ras-GEF domain of hSos1 requires intra-REM domain interactions mediated by phenylalanine 577

artículo científico publicado en 2006

Cell cycle analysis in a human cell line (EUE cells)

artículo científico publicado en 1982

Cell size at S phase initiation: an emergent property of the G1/S network

artículo científico publicado en 2007

Characterization and properties of dominant-negative mutants of the ras-specific guanine nucleotide exchange factor CDC25(Mm).

artículo científico publicado en 1999

Comparative analysis of the molecular mechanisms controlling the initiation of chromosomal DNA replication in yeast and in mammalian cells.

artículo científico

Computational strategies for a system-level understanding of metabolism

artículo científico publicado en 2014

Conglutin gamma, a lupin seed protein, binds insulin in vitro and reduces plasma glucose levels of hyperglycemic rats.

artículo científico publicado en 2004

Control of the yeast cell cycle by protein synthesis.

artículo científico publicado en 1982

Data recovery and integration from public databases uncovers transformation-specific transcriptional downregulation of cAMP-PKA pathway-encoding genes

artículo científico publicado en 2009

Effects of temperature on the yeast cell cycle analyzed by flow cytometry

artículo científico publicado en 1984

Expression of a synthetic gene encoding P2 ribonuclease from the extreme thermoacidophilic archaebacterium Sulfolobus solfataricus in mesophylic hosts

artículo científico publicado en 1995

Expression of cloned Saccharomyces diastaticus glucoamylase under natural and inducible promoters.

artículo científico publicado en 1989

Expression of transforming K-Ras oncogene affects mitochondrial function and morphology in mouse fibroblasts.

artículo científico publicado en 2006

Extreme heat- and pressure-resistant 7-kDa protein P2 from the archaeon Sulfolobus solfataricus is dramatically destabilized by a single-point amino acid substitution ⬇️

artículo científico publicado el 1 de noviembre de 1997

First experimental identification of Ras-inhibitor binding interface using a water-soluble Ras ligand.

artículo científico publicado en 2009

Functional coupling of the mammalian EGF receptor to the Ras/cAMP pathway in the yeast Saccharomyces cerevisiae.

artículo científico publicado en 2008

Glucose modulation of cell size in yeast.

artículo científico publicado en 2005

Glucose signaling-mediated coordination of cell growth and cell cycle in Saccharomyces cerevisiae.

artículo científico publicado en 2010

Glucose-Derived Ras Pathway Inhibitors: Evidence of Ras–Ligand Binding and Ras–GEF (Cdc25) Interaction Inhibition

artículo científico publicado en 2007

Glutamine deprivation induces abortive s-phase rescued by deoxyribonucleotides in k-ras transformed fibroblasts

artículo científico publicado en 2009

Identification and in silico analysis of a new group of double-histone fold-containing proteins

artículo científico publicado en 2005

In CK2 inactivated cells the cyclin dependent kinase inhibitor Sic1 is involved in cell-cycle arrest before the onset of S phase.

artículo científico publicado en 2007

In Saccharomyces cerevisiae a short amino acid sequence facilitates excretion in the growth medium of periplasmic proteins

scientific article published on 01 March 1997

In Saccharomyces cerevisiae an unbalanced level of tyrosine phosphorylation down-regulates the Ras/PKA pathway

artículo científico publicado en 2005

In Saccharomyces cerevisiae, protein secretion into the growth medium depends on environmental factors.

artículo científico publicado en 1993

In budding yeast, reactive oxygen species induce both RAS-dependent and RAS-independent cell cycle-specific arrest

article

Increased p21ras-specific Guanine-nucleotide exchange causes tumor-formation in nude-mice.

artículo científico publicado en 1994

Interactions of ataxin-3 with its molecular partners in the protein machinery that sorts protein aggregates to the aggresome

artículo científico publicado en 2014

K-Ras Activation Induces Differential Sensitivity to Sulfur Amino Acid Limitation and Deprivation and to Oxidative and Anti-Oxidative Stress in Mouse Fibroblasts

artículo científico publicado en 2016

Macromolecular syntheses in the cell cycle mutant cdc25 of budding yeast

scientific article published on 01 October 1984

Methotrexate inhibits SARS-CoV-2 virus replication "in vitro"

artículo científico publicado en 2020

Molecular cloning, nucleotide sequence and expression of a Sulfolobus solfataricus gene encoding a class II fumarase.

artículo científico publicado en 1994

Molecular dynamics simulation of the interaction between the complex iron-sulfur flavoprotein glutamate synthase and its substrates.

artículo científico publicado en 2004

Mutations at position 1122 in the catalytic domain of the mouse ras-specific guanine nucleotide exchange factor CDC25Mm originate both loss-of-function and gain-of-function proteins.

artículo científico publicado en 1998

Mutations of the CK2 phosphorylation site of Sic1 affect cell size and S-Cdk kinase activity in Saccharomyces cerevisiae.

artículo científico publicado en 2004

Novel RasGRF1-derived Tat-fused peptides inhibiting Ras-dependent proliferation and migration in mouse and human cancer cells.

artículo científico publicado en 2011

Order propensity of an intrinsically disordered protein, the cyclin-dependent-kinase inhibitor Sic1

scientific article published on August 2009

Overexpression of Far1, a cyclin-dependent kinase inhibitor, induces a large transcriptional reprogramming in which RNA synthesis senses Far1 in a Sfp1-mediated way

artículo científico publicado en 2011

Overexpression of the CDC25 gene, an upstream element of the ras/adenylyl cyclase pathway in Saccharomyces cerevisiae, allows immunological identification and characterization of its gene product

article

PO-12 - The key role of talin-1 in cancer cell extravasation dissected through human vascularized 3D microfluidic model.

artículo científico publicado en 2016

Phosphorylation of ribosomal protein S10 is dispensable for initiation of DNA replication and bud emergence in Saccharomyces cerevisiae

artículo científico publicado en 1991

Profiling and Targeting of Energy and Redox Metabolism in Grade 2 Bladder Cancer Cells with Different Invasiveness Properties

artículo científico publicado en 2020

Proteomic analysis of a nutritional shift-up in Saccharomyces cerevisiae identifies Gvp36 as a BAR-containing protein involved in vesicular traffic and nutritional adaptation.

artículo científico publicado en 2008

RAS and PKA pathways in cancer: new insight from transcriptional analysis

artículo científico publicado en 2008

Rapamycin-mediated G1 arrest involves regulation of the Cdk inhibitor Sic1 in Saccharomyces cerevisiae

artículo científico publicado en 2007

Ras-dependent carbon metabolism and transformation in mouse fibroblasts

artículo científico publicado en 2006

Real-time flow cytometric quantification of GFP expression and Gfp-fluorescence generation in Saccharomyces cerevisiae

artículo científico publicado en 2000

Redox-Mediated Regulation of p21Waf1/Cip1 Expression Involves a Post-Transcriptional Mechanism and Activation of the Mitogen-Activated Protein Kinase Pathway

scientific article published on 01 May 1997

Regulation of MAL gene expression in yeast: gene dosage effects

scientific article published on 01 October 1987

Regulation of hSos1 activity is a system-level property generated by its multi-domain structure.

artículo científico publicado en 2011

Regulation of maltose utilization in Saccharomyces cerevisiae by genes of the RAS/protein kinase A pathway

scientific article published on 01 February 1997

Relating growth dynamics and glucoamylase excretion of individual Saccharomyces cerevisiae cells

article

Respiratory metabolism and calorie restriction relieve persistent endoplasmic reticulum stress induced by calcium shortage in yeast

artículo científico publicado en 2016

Selective cytotoxicity of a bicyclic Ras inhibitor in cancer cells expressing K-Ras(G13D).

artículo científico publicado en 2009

Sic1 is phosphorylated by CK2 on Ser201 in budding yeast cells

artículo científico publicado en 2006

Snf1/AMPK promotes S-phase entrance by controlling CLB5 transcription in budding yeast.

artículo científico publicado en 2010

Structural heterogeneity in populations of the budding yeast Saccharomyces cerevisiae

artículo científico publicado en 1983

Subcellular localization of the cyclin dependent kinase inhibitor Sic1 is modulated by the carbon source in budding yeast.

artículo científico publicado en 2005

Systems biology for biomedical innovation

article

The Ras Guanine nucleotide Exchange Factor CDC25Mm is present at the synaptic junction.

artículo científico publicado en 1997

The Sso7d DNA-binding protein from Sulfolobus solfataricus has ribonuclease activity

artículo científico publicado en 2001

The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and mitogen-activated protein kinase-dependent activation of paxillin

artículo científico publicado en 2010

The isolated catalytic hairpin of the Ras-specific guanine nucleotide exchange factor Cdc25Mm retains nucleotide dissociation activity but has impaired nucleotide exchange activity.

artículo científico publicado en 2005

The role of hexose transport and phosphorylation in cAMP signalling in the yeast Saccharomyces cerevisiae.

artículo científico publicado en 2001

The yeast cyclin-dependent kinase inhibitor Sic1 and mammalian p27Kip1 are functional homologues with a structurally conserved inhibitory domain

artículo científico publicado en 2005

Tipifarnib as a Precision Therapy for HRAS-Mutant Head and Neck Squamous Cell Carcinomas

artículo científico publicado en 2020

Towards a systems biology approach to mammalian cell cycle: modeling the entrance into S phase of quiescent fibroblasts after serum stimulation

artículo científico publicado en 2009

Transcriptomics and Metabolomics Integration Reveals Redox-Dependent Metabolic Rewiring in Breast Cancer Cells

artículo científico publicado en 2021

Whi5 phosphorylation embedded in the G1/S network dynamically controls critical cell size and cell fate.

artículo científico publicado en 2016

Zooming-in on cancer metabolic rewiring with tissue specific constraint-based models

artículo científico publicado en 2016

Lista de obras de Marco Vanoni

5-fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits

A 9359 bp fragment from the right arm ofSaccharomyces cerevisiae chromosome VII includes theFOL2 andYTA7 genes and three unknown open reading frames ⬇️

A cell sizer network involving Cln3 and Far1 controls entrance into S phase in the mitotic cycle of budding yeast.

A comparative study of Whi5 and retinoblastoma proteins: from sequence and structure analysis to intracellular networks.

A computer algorithm for the analysis of protein distribution in budding yeast.

A dominant negative RAS-specific guanine nucleotide exchange factor reverses neoplastic phenotype in K-ras transformed mouse fibroblasts.

A metabolic core model elucidates how enhanced utilization of glucose and glutamine, with enhanced glutamine-dependent lactate production, promotes cancer cell growth: The WarburQ effect

A mouse CDC25-like product enhances the formation of the active GTP complex of human ras p21 and Saccharomyces cerevisiae RAS2 proteins

A systems biology road map for the discovery of drugs targeting cancer cell metabolism.

Acquired glucose sensitivity of k-ras transformed fibroblasts.

An acidic loop and cognate phosphorylation sites define a molecular switch that modulates ubiquitin charging activity in Cdc34-like enzymes

Approaches to Ras signaling modulation and treatment of Ras-dependent disorders: a patent review (2007--present).

Biochemical and immunological characterization of the STA2-encoded extracellular glucoamylase from saccharomyces diastaticus

CK2 regulates in vitro the activity of the yeast cyclin-dependent kinase inhibitor Sic1

Cancer cell growth and survival as a system-level property sustained by enhanced glycolysis and mitochondrial metabolic remodeling

Catalytic competence of the Ras-GEF domain of hSos1 requires intra-REM domain interactions mediated by phenylalanine 577

Cell cycle analysis in a human cell line (EUE cells)

Cell size at S phase initiation: an emergent property of the G1/S network

Characterization and properties of dominant-negative mutants of the ras-specific guanine nucleotide exchange factor CDC25(Mm).

Comparative analysis of the molecular mechanisms controlling the initiation of chromosomal DNA replication in yeast and in mammalian cells.

Computational strategies for a system-level understanding of metabolism

Conglutin gamma, a lupin seed protein, binds insulin in vitro and reduces plasma glucose levels of hyperglycemic rats.

Control of the yeast cell cycle by protein synthesis.

Data recovery and integration from public databases uncovers transformation-specific transcriptional downregulation of cAMP-PKA pathway-encoding genes

Effects of temperature on the yeast cell cycle analyzed by flow cytometry

Expression of a synthetic gene encoding P2 ribonuclease from the extreme thermoacidophilic archaebacterium Sulfolobus solfataricus in mesophylic hosts

Expression of cloned Saccharomyces diastaticus glucoamylase under natural and inducible promoters.

Expression of transforming K-Ras oncogene affects mitochondrial function and morphology in mouse fibroblasts.

Extreme heat- and pressure-resistant 7-kDa protein P2 from the archaeon Sulfolobus solfataricus is dramatically destabilized by a single-point amino acid substitution ⬇️

First experimental identification of Ras-inhibitor binding interface using a water-soluble Ras ligand.

Functional coupling of the mammalian EGF receptor to the Ras/cAMP pathway in the yeast Saccharomyces cerevisiae.

Glucose modulation of cell size in yeast.

Glucose signaling-mediated coordination of cell growth and cell cycle in Saccharomyces cerevisiae.

Glucose-Derived Ras Pathway Inhibitors: Evidence of Ras–Ligand Binding and Ras–GEF (Cdc25) Interaction Inhibition

Glutamine deprivation induces abortive s-phase rescued by deoxyribonucleotides in k-ras transformed fibroblasts

Identification and in silico analysis of a new group of double-histone fold-containing proteins

In CK2 inactivated cells the cyclin dependent kinase inhibitor Sic1 is involved in cell-cycle arrest before the onset of S phase.

In Saccharomyces cerevisiae a short amino acid sequence facilitates excretion in the growth medium of periplasmic proteins

In Saccharomyces cerevisiae an unbalanced level of tyrosine phosphorylation down-regulates the Ras/PKA pathway

In Saccharomyces cerevisiae, protein secretion into the growth medium depends on environmental factors.

In budding yeast, reactive oxygen species induce both RAS-dependent and RAS-independent cell cycle-specific arrest

Increased p21ras-specific Guanine-nucleotide exchange causes tumor-formation in nude-mice.

Interactions of ataxin-3 with its molecular partners in the protein machinery that sorts protein aggregates to the aggresome

K-Ras Activation Induces Differential Sensitivity to Sulfur Amino Acid Limitation and Deprivation and to Oxidative and Anti-Oxidative Stress in Mouse Fibroblasts

Macromolecular syntheses in the cell cycle mutant cdc25 of budding yeast

Methotrexate inhibits SARS-CoV-2 virus replication "in vitro"

Molecular cloning, nucleotide sequence and expression of a Sulfolobus solfataricus gene encoding a class II fumarase.

Molecular dynamics simulation of the interaction between the complex iron-sulfur flavoprotein glutamate synthase and its substrates.

Mutations at position 1122 in the catalytic domain of the mouse ras-specific guanine nucleotide exchange factor CDC25Mm originate both loss-of-function and gain-of-function proteins.

Mutations of the CK2 phosphorylation site of Sic1 affect cell size and S-Cdk kinase activity in Saccharomyces cerevisiae.

Novel RasGRF1-derived Tat-fused peptides inhibiting Ras-dependent proliferation and migration in mouse and human cancer cells.

Order propensity of an intrinsically disordered protein, the cyclin-dependent-kinase inhibitor Sic1

Overexpression of Far1, a cyclin-dependent kinase inhibitor, induces a large transcriptional reprogramming in which RNA synthesis senses Far1 in a Sfp1-mediated way

Overexpression of the CDC25 gene, an upstream element of the ras/adenylyl cyclase pathway in Saccharomyces cerevisiae, allows immunological identification and characterization of its gene product

PO-12 - The key role of talin-1 in cancer cell extravasation dissected through human vascularized 3D microfluidic model.

Phosphorylation of ribosomal protein S10 is dispensable for initiation of DNA replication and bud emergence in Saccharomyces cerevisiae

Profiling and Targeting of Energy and Redox Metabolism in Grade 2 Bladder Cancer Cells with Different Invasiveness Properties

Proteomic analysis of a nutritional shift-up in Saccharomyces cerevisiae identifies Gvp36 as a BAR-containing protein involved in vesicular traffic and nutritional adaptation.

RAS and PKA pathways in cancer: new insight from transcriptional analysis

Rapamycin-mediated G1 arrest involves regulation of the Cdk inhibitor Sic1 in Saccharomyces cerevisiae

Ras-dependent carbon metabolism and transformation in mouse fibroblasts

Real-time flow cytometric quantification of GFP expression and Gfp-fluorescence generation in Saccharomyces cerevisiae

Redox-Mediated Regulation of p21Waf1/Cip1 Expression Involves a Post-Transcriptional Mechanism and Activation of the Mitogen-Activated Protein Kinase Pathway

Regulation of MAL gene expression in yeast: gene dosage effects

Regulation of hSos1 activity is a system-level property generated by its multi-domain structure.

Regulation of maltose utilization in Saccharomyces cerevisiae by genes of the RAS/protein kinase A pathway

Relating growth dynamics and glucoamylase excretion of individual Saccharomyces cerevisiae cells

Respiratory metabolism and calorie restriction relieve persistent endoplasmic reticulum stress induced by calcium shortage in yeast

Selective cytotoxicity of a bicyclic Ras inhibitor in cancer cells expressing K-Ras(G13D).

Sic1 is phosphorylated by CK2 on Ser201 in budding yeast cells

Snf1/AMPK promotes S-phase entrance by controlling CLB5 transcription in budding yeast.

Structural heterogeneity in populations of the budding yeast Saccharomyces cerevisiae

Subcellular localization of the cyclin dependent kinase inhibitor Sic1 is modulated by the carbon source in budding yeast.

Systems biology for biomedical innovation

The Ras Guanine nucleotide Exchange Factor CDC25Mm is present at the synaptic junction.

The Sso7d DNA-binding protein from Sulfolobus solfataricus has ribonuclease activity

The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and mitogen-activated protein kinase-dependent activation of paxillin

The isolated catalytic hairpin of the Ras-specific guanine nucleotide exchange factor Cdc25Mm retains nucleotide dissociation activity but has impaired nucleotide exchange activity.

The role of hexose transport and phosphorylation in cAMP signalling in the yeast Saccharomyces cerevisiae.