Lista de obras - Stephen Traynelis - Dominio Público Uruguay

A Novel Negative Allosteric Modulator Selective for GluN2C/2D-Containing NMDA Receptors Inhibits Synaptic Transmission in Hippocampal Interneurons.

artículo científico publicado en 2017

A Rare Variant Identified Within the GluN2B C-Terminus in a Patient with Autism Affects NMDA Receptor Surface Expression and Spine Density

artículo científico publicado en 2017

A structurally derived model of subunit-dependent NMDA receptor function

artículo científico publicado en 2018

Additional Depth to the NMDA Receptor Hypofunction and Parvalbumin Cell Dysfunction Hypotheses of Schizophrenia

artículo científico publicado en 2023

Allosteric Modulation of Ionotropic Glutamate Receptors Special Issue

artículo científico publicado en 2018

Allosteric Modulation of Ionotropic Glutamate Receptors Special Issue

artículo científico publicado en 2019

An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups.

artículo científico publicado en 2018

Biased modulators of NMDA receptors control channel opening and ion selectivity

scientific article published on 20 January 2020

Crystal Structure and Pharmacological Characterization of a Novel N-Methyl-D-aspartate (NMDA) Receptor Antagonist at the GluN1 Glycine Binding Site

artículo científico publicado en 2013

De novo GRIN variants in NMDA receptor M2 channel pore-forming loop are associated with neurological diseases

artículo científico publicado en 2019

Development of 2'-substituted (2S,1'R,2'S)-2-(carboxycyclopropyl)glycine analogues as potent N-methyl-d-aspartic acid receptor agonists

artículo científico publicado en 2013

Di-aryl Sulfonamide Motif Adds π-Stacking Bulk in Negative Allosteric Modulators of the NMDA Receptor

artículo científico publicado en 2019

Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of <i>N</i>-Methyl-d-aspartate Receptors

artículo científico publicado en 2020

Functional and pharmacological properties of triheteromeric GluN1/2B/2D NMDA receptors

artículo científico publicado en 2019

Hodgkin-huxley-katz prize lecture: genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif

artículo científico publicado en 2020

Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists

artículo científico publicado en 2010

NMDA Receptors Containing the GluN2D Subunit Control Neuronal Function in the Subthalamic Nucleus

artículo científico publicado en 2015

NMDA receptor blockade ameliorates abnormalities of spike firing of subthalamic nucleus neurons in a parkinsonian nonhuman primate.

artículo científico publicado en 2018

Pedunculopontine glutamatergic neurons control spike patterning in substantia nigra dopaminergic neurons.

artículo científico publicado en 2017

Regulation of GluA1 α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor function by protein kinase C at serine-818 and threonine-840

artículo científico publicado en 2014

Structure, function, and allosteric modulation of NMDA receptors

scientific article published on 23 July 2018

Synaptic Receptor Diversity Revealed Across Space and Time

artículo científico publicado en 2018

Synthesis and Preliminary Evaluations of a Triazole-Cored Antagonist as a PET Imaging Probe ([18F]N2B-0518) for GluN2B Subunit in the Brain

artículo científico publicado en 2019

The First 50 Years of Molecular Pharmacology

artículo científico publicado en 2015

The GRIA3 c.2477G > A Variant Causes an Exaggerated Startle Reflex, Chorea, and Multifocal Myoclonus

scientific article published on 05 May 2020

The GluN2B-Glu413Gly NMDA receptor variant arising from a de novo GRIN2B mutation promotes ligand-unbinding and domain opening

artículo científico publicado en 2018

The Structure-Activity Relationship of a Tetrahydroisoquinoline Class of N-Methyl-d-Aspartate Receptor Modulators that Potentiates GluN2B-Containing N-Methyl-d-Aspartate Receptors.

artículo científico publicado en 2017

Tonic Activation of GluN2C/GluN2D-Containing NMDA Receptors by Ambient Glutamate Facilitates Cortical Interneuron Maturation

artículo científico publicado en 2019

Lista de obras de Stephen Traynelis

A Novel Negative Allosteric Modulator Selective for GluN2C/2D-Containing NMDA Receptors Inhibits Synaptic Transmission in Hippocampal Interneurons.

A Rare Variant Identified Within the GluN2B C-Terminus in a Patient with Autism Affects NMDA Receptor Surface Expression and Spine Density

A structurally derived model of subunit-dependent NMDA receptor function

Additional Depth to the NMDA Receptor Hypofunction and Parvalbumin Cell Dysfunction Hypotheses of Schizophrenia

Allosteric Modulation of Ionotropic Glutamate Receptors Special Issue

Allosteric Modulation of Ionotropic Glutamate Receptors Special Issue

An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups.

Biased modulators of NMDA receptors control channel opening and ion selectivity

Crystal Structure and Pharmacological Characterization of a Novel N-Methyl-D-aspartate (NMDA) Receptor Antagonist at the GluN1 Glycine Binding Site

De novo GRIN variants in NMDA receptor M2 channel pore-forming loop are associated with neurological diseases

Development of 2'-substituted (2S,1'R,2'S)-2-(carboxycyclopropyl)glycine analogues as potent N-methyl-d-aspartic acid receptor agonists

Di-aryl Sulfonamide Motif Adds π-Stacking Bulk in Negative Allosteric Modulators of the NMDA Receptor

Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of <i>N</i>-Methyl-d-aspartate Receptors

Functional and pharmacological properties of triheteromeric GluN1/2B/2D NMDA receptors

Hodgkin-huxley-katz prize lecture: genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif

Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists

NMDA Receptors Containing the GluN2D Subunit Control Neuronal Function in the Subthalamic Nucleus

NMDA receptor blockade ameliorates abnormalities of spike firing of subthalamic nucleus neurons in a parkinsonian nonhuman primate.

Pedunculopontine glutamatergic neurons control spike patterning in substantia nigra dopaminergic neurons.

Regulation of GluA1 α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor function by protein kinase C at serine-818 and threonine-840

Structure, function, and allosteric modulation of NMDA receptors

Synaptic Receptor Diversity Revealed Across Space and Time

Synthesis and Preliminary Evaluations of a Triazole-Cored Antagonist as a PET Imaging Probe ([18F]N2B-0518) for GluN2B Subunit in the Brain

The First 50 Years of Molecular Pharmacology

The GRIA3 c.2477G > A Variant Causes an Exaggerated Startle Reflex, Chorea, and Multifocal Myoclonus

The GluN2B-Glu413Gly NMDA receptor variant arising from a de novo GRIN2B mutation promotes ligand-unbinding and domain opening

The Structure-Activity Relationship of a Tetrahydroisoquinoline Class of N-Methyl-d-Aspartate Receptor Modulators that Potentiates GluN2B-Containing N-Methyl-d-Aspartate Receptors.

Tonic Activation of GluN2C/GluN2D-Containing NMDA Receptors by Ambient Glutamate Facilitates Cortical Interneuron Maturation