Lista de obras - Domenico Osella - Dominio Público Uruguay

195Pt NMR spectroscopy: A chemometric approach

A New Entry to Asymmetric Platinum(IV) Complexes via Oxidative Chlorination

artículo científico publicado en 2014

A multi-methodological inquiry of the behavior of cisplatin-based Pt(IV) derivatives in the presence of bioreductants with a focus on the isolated encounter complexes

scientific article published on 15 April 2020

An unsymmetric cisplatin-based Pt(iv) derivative containing 2-(2-propynyl)octanoate: a very efficient multi-action antitumor prodrug candidate

artículo científico publicado en 2017

Antiproliferative Activity of Pt(IV) Conjugates Containing the Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Ketoprofen and Naproxen †

scientific article published on 24 June 2019

Antiproliferative Activity of PtII Complexes with Carboxylated Phosphanes in Chelated or Ring-Opened Forms

Antiproliferative Pt(IV) complexes: synthesis, biological activity, and quantitative structure–activity relationship modeling

article

Antiproliferative activity of Pt(IV)-bis(carboxylato) conjugates on malignant pleural mesothelioma cells

artículo científico publicado en 2013

Antiproliferative activity of a series of cisplatin-based Pt(IV)-acetylamido/carboxylato prodrugs

artículo científico publicado en 2016

Antiproliferative effect of ferrocifen drug candidates on malignant pleural mesothelioma cell lines

Authentication and traceability study of hazelnuts from piedmont, Italy.

artículo científico publicado en 2009

Biological activity of a series of cisplatin-based aliphatic bis(carboxylato) Pt(IV) prodrugs: how long the organic chain should be?

artículo científico publicado en 2014

Biological activity of enantiomeric complexes [PtCl(2)L (2)] (L (2) is aromatic bisphosphanes and aromatic diamines).

artículo científico publicado en 2010

Can the Self-Assembling of Dicarboxylate Pt(IV) Prodrugs Influence Their Cell Uptake?

artículo científico publicado en 2021

Cellular trafficking, accumulation and DNA platination of a series of cisplatin-based dicarboxylato Pt(IV) prodrugs

artículo científico publicado en 2015

Cis-[Pt(Cl)2(pyridine)(5-SO3H-isoquinoline)] complex, a selective inhibitor of telomerase enzyme.

artículo científico publicado en 2003

Cisplatin and valproate released from the bifunctional [Pt(IV)Cl2(NH3)2(valproato)2] antitumor prodrug or from liposome formulations: who does what?

artículo científico publicado en 2017

Cytotoxicity of cis-platinum(II) conjugate models. The effect of chelating arms and leaving groups on cytotoxicity: a quantitative structure-activity relationship approach.

artículo científico publicado en 2005

Effect of arbuscular mycorrhizal and bacterial inocula on nitrate concentration in mesocosms simulating a wastewater treatment system relying on phytodepuration.

artículo científico publicado en 2015

Electrochemical Biosensor Assay of the Interaction between [PtCln(NH3)4-n](2-n) (n = 0-4) Complexes and ds-DNA

Electrochemical evaluation of the interaction between antitumoral titanocene dichloride and biomolecules

Electrochemical measurements confirm the preferential bonding of the antimetastatic complex [ImH][RuCl(4)(DMSO)(Im)] (NAMI-A) with proteins and the weak interaction with nucleobases

artículo científico publicado en 2004

Electrochemical studies of a series of antimetastatic mono- and di-ruthenium complexes [Na][trans-RuIIICl4(DMSO)(L)] and [Na]2[{trans-RuIIICl4(DMSO)}2(μ-L)] (L=N-donor heterocyclic bridging ligand)

Electrostatic Interaction of Negatively Charged Core-Shell Nanoparticles with Antitumoral Cationic Platinum-Based Complexes

Enhancement of the cytotoxicity of titanocene dichloride by aging in organic co-solvent.

artículo científico publicado en 2005

Estrogen derivatives of transition metal carbonyl clusters for analytical detection enhancement

Estrogen derivatives of transition metal complexes for analytical detection enhancement. Part II

Evaluation of Platinum-Ethacrynic Acid Conjugates in the Treatment of Mesothelioma

artículo científico publicado en 2011

FACS analysis of oxidative stress induced on tumour cells by SERMs

Functional fluorescent nonporous silica nanoparticles as carriers for Pt(IV) anticancer prodrugs

artículo científico publicado en 2015

Functionalized nonporous silica nanoparticles as carriers for Pt(iv) anticancer prodrugs.

artículo científico publicado en 2016

Functionalized thymidine derivatives as carriers for the γ-emitter technetium tricarbonyl moiety

Haemolymph from Mytilus galloprovincialis: Response to copper and temperature challenges studied by (1)H-NMR metabonomics.

artículo científico publicado en 2016

Host–guest inclusion systems of Pt(IV)-bis(benzoato) anticancer drug candidates and cyclodextrins

Hybrid inorganic (nonporous silica)/organic (alginate) core-shell platform for targeting a cisplatin-based Pt(IV) anticancer prodrug

article published in 2018

In vitro anti-mesothelioma activity of cisplatin-gemcitabine combinations: evidence for sequence-dependent effects

artículo científico publicado en 2010

Inhibition of Stat3 increases doxorubicin sensitivity in a human metastatic breast cancer cell line

artículo científico publicado en 2007

May glutamine addiction drive the delivery of antitumor cisplatin-based Pt(IV) prodrugs?

artículo científico publicado en 2016

Metallo-drugs in the treatment of malignant pleural mesothelioma

Molecular and statistical modeling of reduction peak potential and lipophilicity of platinum(IV) complexes.

artículo científico publicado en 2010

Molecular interaction fields vs. quantum-mechanical-based descriptors in the modelling of lipophilicity of platinum(IV) complexes.

artículo científico publicado en 2012

Oxidative degradation of 1,5-naphthalenedisulfonic acid in aqueous solutions by UV-photolysis in the absence and presence of H2O2.

artículo científico publicado en 2010

Oxidative degradation of 1,5-naphthalenedisulfonic acid in aqueous solutions by microwave irradiation in the presence of H2O2.

artículo científico publicado en 2008

Oxidative stress and total antioxidant capacity in human plasma

scientific article published on 01 January 2009

Platinum(II) and technetium(I) complexes anchored to ethynylestradiol: a way to drug targeting and delivery

Platinum-bisphosphonate complexes have proven to be inactive chemotherapeutics targeted for malignant mesothelioma because of inappropriate hydrolysis

artículo científico publicado en 2010

Poly(methylmetacrylate) (PMMA) core–shell nanospheres act as efficient pharmacophores for the antiproliferative [PtCl3(NH3)]− complex by forming ionic couples

Polyanionic Biopolymers for the Delivery of Pt(II) Cationic Antiproliferative Complexes

artículo científico publicado en 2016

Pros and cons of bifunctional platinum(iv) antitumor prodrugs: two are (not always) better than one

artículo científico publicado en 2014

Pt(IV) Bifunctional Prodrug Containing 2-(2-Propynyl)octanoato Axial Ligand: Induction of Immunogenic Cell Death on Colon Cancer

artículo científico publicado en 2019

Radical scavenging abilities of fish MT-A and mussel MT-10 metallothionein isoforms: An ESR study.

artículo científico publicado en 2007

Reactions of the co-ordinatively unsaturated cluster [Os3(µ-H)(CO)8{Ph2PCH2P(Ph)C6H4}] with alkynes RCCR (R = Ph, C6H4Me, Me or CF3); crystal structures of [Os3(CO)8{µ3–η2(∥)–RC2R}(Ph2PCH2PPh2)](R = Me or CF3) and electrochemical behaviou

Revisiting [PtCl₂(cis-1,4-DACH)]: an underestimated antitumor drug with potential application to the treatment of oxaliplatin-refractory colorectal cancer.

artículo científico publicado en 2012

Solvolysis of a Series of Cisplatin-Like Complexes - Comparison between DNA-Biosensor and Conductivity Data

Stepwise assembly of platinum–folic acid conjugates

Synthesis and characterisation of estrogenic carriers for cytotoxic Pt(II) fragments: biological activity of the resulting complexes

artículo científico publicado en 2005

Synthesis and characterization of cyclohexane-1R,2R-diamine-based Pt(iv) dicarboxylato anticancer prodrugs: their selective activity against human colon cancer cell lines

artículo científico publicado en 2019

Synthesis, characterization and antiproliferative activity on mesothelioma cell lines of bis(carboxylato)platinum(IV) complexes based on picoplatin.

artículo científico publicado en 2012

Synthesis, characterization, structure, molecular modeling studies and biological activity of sterically crowded Pt(II) complexes containing bis(imidazole) ligands

artículo científico publicado en 2010

Telomerase inhibition and cancer: might platinum based drugs have a future as anti-telomerase pharmacological approach?

artículo científico publicado en 2005

The Drug Targeting and Delivery Approach Applied to Pt-Antitumour Complexes. A Coordination Point of View

artículo científico publicado en 2009

The RP-HPLC measurement and QSPR analysis of logP(o/w) values of several Pt(II) complexes.

artículo científico publicado en 2006

The activation of platinum(II) antiproliferative drugs in carbonate medium evaluated by means of a DNA-biosensor

artículo científico publicado en 2007

The cadmium binding domains in the metallothionein isoform Cd(7)-MT10 from Mytilus galloprovincialis revealed by NMR spectroscopy.

artículo científico publicado en 2008

The cisplatin-based Pt(iv)-diclorofibrato multi-action anticancer prodrug exhibits excellent performances also under hypoxic conditions

scientific article published on 01 June 2018

The hexacarbonyldicobalt derivative of aspirin acts as a CO-releasing NSAID on malignant mesothelioma cells

artículo científico publicado en 2013

The influence of temperature on antiproliferative effects, cellular uptake and DNA platination of the clinically employed Pt(II)-drugs

artículo científico publicado en 2007

The relevance of polar surface area (PSA) in rationalizing biological properties of several cis-diamminemalonatoplatinum(II) derivatives

artículo científico publicado en 2009

Transition metal carbonyl clusters in biology: A futile or niche research area?

Transition metal complexes as electrochemical markers for steroids

Trend in cytotoxic activity of a series of cis-[APtCl2] (A=ethylenediamine methylated at different positions) complexes

Unprecedented one-pot synthesis of an unsymmetrical cisplatin-based Pt(iv)–acetamidato complex

scientific article published on 13 April 2015

Uptake of antitumor platinum(II)-complexes by cancer cells, assayed by inductively coupled plasma mass spectrometry (ICP-MS).

artículo científico publicado en 2004

Use of Heavy-Metal Clusters in the Design of N-Succinimidyl Ester Acylation Reagents for Side-Chain-Specific Labeling of Proteins

artículo científico publicado en 1999

Water stability and cytotoxic activity relationship of a series of ferrocenium derivatives. ESR insights on the radical production during the degradation process.

artículo científico publicado en 2002

Water-soluble benzoheterocycle triosmium clusters as potential inhibitors of telomerase enzyme.

artículo científico publicado en 2005

trans,cis,cis-bis(benzoato)dichlorido(cyclohexane-1R,2R-diamine)platinum(IV): a prodrug candidate for the treatment of oxaliplatin-refractory colorectal cancer

artículo científico publicado en 2014

Lista de obras de Domenico Osella

195Pt NMR spectroscopy: A chemometric approach

A New Entry to Asymmetric Platinum(IV) Complexes via Oxidative Chlorination

A multi-methodological inquiry of the behavior of cisplatin-based Pt(IV) derivatives in the presence of bioreductants with a focus on the isolated encounter complexes

An unsymmetric cisplatin-based Pt(iv) derivative containing 2-(2-propynyl)octanoate: a very efficient multi-action antitumor prodrug candidate

Antiproliferative Activity of Pt(IV) Conjugates Containing the Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Ketoprofen and Naproxen †

Antiproliferative Activity of PtII Complexes with Carboxylated Phosphanes in Chelated or Ring-Opened Forms

Antiproliferative Pt(IV) complexes: synthesis, biological activity, and quantitative structure–activity relationship modeling

Antiproliferative activity of Pt(IV)-bis(carboxylato) conjugates on malignant pleural mesothelioma cells

Antiproliferative activity of a series of cisplatin-based Pt(IV)-acetylamido/carboxylato prodrugs

Antiproliferative effect of ferrocifen drug candidates on malignant pleural mesothelioma cell lines

Authentication and traceability study of hazelnuts from piedmont, Italy.

Biological activity of a series of cisplatin-based aliphatic bis(carboxylato) Pt(IV) prodrugs: how long the organic chain should be?

Biological activity of enantiomeric complexes [PtCl(2)L (2)] (L (2) is aromatic bisphosphanes and aromatic diamines).

Can the Self-Assembling of Dicarboxylate Pt(IV) Prodrugs Influence Their Cell Uptake?

Cellular trafficking, accumulation and DNA platination of a series of cisplatin-based dicarboxylato Pt(IV) prodrugs

Cis-[Pt(Cl)2(pyridine)(5-SO3H-isoquinoline)] complex, a selective inhibitor of telomerase enzyme.

Cisplatin and valproate released from the bifunctional [Pt(IV)Cl2(NH3)2(valproato)2] antitumor prodrug or from liposome formulations: who does what?

Cytotoxicity of cis-platinum(II) conjugate models. The effect of chelating arms and leaving groups on cytotoxicity: a quantitative structure-activity relationship approach.

Effect of arbuscular mycorrhizal and bacterial inocula on nitrate concentration in mesocosms simulating a wastewater treatment system relying on phytodepuration.

Electrochemical Biosensor Assay of the Interaction between [PtCln(NH3)4-n](2-n) (n = 0-4) Complexes and ds-DNA

Electrochemical evaluation of the interaction between antitumoral titanocene dichloride and biomolecules

Electrochemical measurements confirm the preferential bonding of the antimetastatic complex [ImH][RuCl(4)(DMSO)(Im)] (NAMI-A) with proteins and the weak interaction with nucleobases

Electrochemical studies of a series of antimetastatic mono- and di-ruthenium complexes [Na][trans-RuIIICl4(DMSO)(L)] and [Na]2[{trans-RuIIICl4(DMSO)}2(μ-L)] (L=N-donor heterocyclic bridging ligand)

Electrostatic Interaction of Negatively Charged Core-Shell Nanoparticles with Antitumoral Cationic Platinum-Based Complexes

Enhancement of the cytotoxicity of titanocene dichloride by aging in organic co-solvent.

Estrogen derivatives of transition metal carbonyl clusters for analytical detection enhancement

Estrogen derivatives of transition metal complexes for analytical detection enhancement. Part II

Evaluation of Platinum-Ethacrynic Acid Conjugates in the Treatment of Mesothelioma

FACS analysis of oxidative stress induced on tumour cells by SERMs

Functional fluorescent nonporous silica nanoparticles as carriers for Pt(IV) anticancer prodrugs

Functionalized nonporous silica nanoparticles as carriers for Pt(iv) anticancer prodrugs.

Functionalized thymidine derivatives as carriers for the γ-emitter technetium tricarbonyl moiety

Haemolymph from Mytilus galloprovincialis: Response to copper and temperature challenges studied by (1)H-NMR metabonomics.

Host–guest inclusion systems of Pt(IV)-bis(benzoato) anticancer drug candidates and cyclodextrins

Hybrid inorganic (nonporous silica)/organic (alginate) core-shell platform for targeting a cisplatin-based Pt(IV) anticancer prodrug

In vitro anti-mesothelioma activity of cisplatin-gemcitabine combinations: evidence for sequence-dependent effects

Inhibition of Stat3 increases doxorubicin sensitivity in a human metastatic breast cancer cell line

May glutamine addiction drive the delivery of antitumor cisplatin-based Pt(IV) prodrugs?

Metallo-drugs in the treatment of malignant pleural mesothelioma

Molecular and statistical modeling of reduction peak potential and lipophilicity of platinum(IV) complexes.

Molecular interaction fields vs. quantum-mechanical-based descriptors in the modelling of lipophilicity of platinum(IV) complexes.

Oxidative degradation of 1,5-naphthalenedisulfonic acid in aqueous solutions by UV-photolysis in the absence and presence of H2O2.

Oxidative degradation of 1,5-naphthalenedisulfonic acid in aqueous solutions by microwave irradiation in the presence of H2O2.

Oxidative stress and total antioxidant capacity in human plasma

Platinum(II) and technetium(I) complexes anchored to ethynylestradiol: a way to drug targeting and delivery

Platinum-bisphosphonate complexes have proven to be inactive chemotherapeutics targeted for malignant mesothelioma because of inappropriate hydrolysis

Poly(methylmetacrylate) (PMMA) core–shell nanospheres act as efficient pharmacophores for the antiproliferative [PtCl3(NH3)]− complex by forming ionic couples

Polyanionic Biopolymers for the Delivery of Pt(II) Cationic Antiproliferative Complexes

Pros and cons of bifunctional platinum(iv) antitumor prodrugs: two are (not always) better than one

Pt(IV) Bifunctional Prodrug Containing 2-(2-Propynyl)octanoato Axial Ligand: Induction of Immunogenic Cell Death on Colon Cancer

Radical scavenging abilities of fish MT-A and mussel MT-10 metallothionein isoforms: An ESR study.

Reactions of the co-ordinatively unsaturated cluster [Os3(µ-H)(CO)8{Ph2PCH2P(Ph)C6H4}] with alkynes RCCR (R = Ph, C6H4Me, Me or CF3); crystal structures of [Os3(CO)8{µ3–η2(∥)–RC2R}(Ph2PCH2PPh2)](R = Me or CF3) and electrochemical behaviou

Revisiting [PtCl₂(cis-1,4-DACH)]: an underestimated antitumor drug with potential application to the treatment of oxaliplatin-refractory colorectal cancer.

Solvolysis of a Series of Cisplatin-Like Complexes - Comparison between DNA-Biosensor and Conductivity Data

Stepwise assembly of platinum–folic acid conjugates

Synthesis and characterisation of estrogenic carriers for cytotoxic Pt(II) fragments: biological activity of the resulting complexes

Synthesis and characterization of cyclohexane-1R,2R-diamine-based Pt(iv) dicarboxylato anticancer prodrugs: their selective activity against human colon cancer cell lines

Synthesis, characterization and antiproliferative activity on mesothelioma cell lines of bis(carboxylato)platinum(IV) complexes based on picoplatin.

Synthesis, characterization, structure, molecular modeling studies and biological activity of sterically crowded Pt(II) complexes containing bis(imidazole) ligands

Telomerase inhibition and cancer: might platinum based drugs have a future as anti-telomerase pharmacological approach?

The Drug Targeting and Delivery Approach Applied to Pt-Antitumour Complexes. A Coordination Point of View

The RP-HPLC measurement and QSPR analysis of logP(o/w) values of several Pt(II) complexes.

The activation of platinum(II) antiproliferative drugs in carbonate medium evaluated by means of a DNA-biosensor

The cadmium binding domains in the metallothionein isoform Cd(7)-MT10 from Mytilus galloprovincialis revealed by NMR spectroscopy.

The cisplatin-based Pt(iv)-diclorofibrato multi-action anticancer prodrug exhibits excellent performances also under hypoxic conditions

The hexacarbonyldicobalt derivative of aspirin acts as a CO-releasing NSAID on malignant mesothelioma cells

The influence of temperature on antiproliferative effects, cellular uptake and DNA platination of the clinically employed Pt(II)-drugs

The relevance of polar surface area (PSA) in rationalizing biological properties of several cis-diamminemalonatoplatinum(II) derivatives

Transition metal carbonyl clusters in biology: A futile or niche research area?

Transition metal complexes as electrochemical markers for steroids

Trend in cytotoxic activity of a series of cis-[APtCl2] (A=ethylenediamine methylated at different positions) complexes

Unprecedented one-pot synthesis of an unsymmetrical cisplatin-based Pt(iv)–acetamidato complex

Uptake of antitumor platinum(II)-complexes by cancer cells, assayed by inductively coupled plasma mass spectrometry (ICP-MS).

Use of Heavy-Metal Clusters in the Design of N-Succinimidyl Ester Acylation Reagents for Side-Chain-Specific Labeling of Proteins

Water stability and cytotoxic activity relationship of a series of ferrocenium derivatives. ESR insights on the radical production during the degradation process.

Water-soluble benzoheterocycle triosmium clusters as potential inhibitors of telomerase enzyme.

trans,cis,cis-bis(benzoato)dichlorido(cyclohexane-1R,2R-diamine)platinum(IV): a prodrug candidate for the treatment of oxaliplatin-refractory colorectal cancer