Lista de obras - Christopher A Ahern - Dominio Público Uruguay

A Conserved Residue Cluster That Governs Kinetics of ATP-dependent Gating of Kir6.2 Potassium Channels

artículo científico publicado en 2015

A cation-pi interaction between extracellular TEA and an aromatic residue in potassium channels.

artículo científico publicado en 2006

A cation-pi interaction discriminates among sodium channels that are either sensitive or resistant to tetrodotoxin block.

artículo científico publicado en 2007

A component of excitation-contraction coupling triggered in the absence of the T671-L690 and L720-Q765 regions of the II-III loop of the dihydropyridine receptor alpha(1s) pore subunit.

artículo científico publicado en 2001

A novel mechanism for fine-tuning open-state stability in a voltage-gated potassium channel.

artículo científico publicado en 2013

An electrostatic interaction between TEA and an introduced pore aromatic drives spring-in-the-door inactivation in Shaker potassium channels

artículo científico publicado en 2009

Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains

artículo científico publicado en 2014

Atom-by-atom engineering of voltage-gated ion channels: magnified insights into function and pharmacology

artículo científico publicado en 2015

Atomic basis for therapeutic activation of neuronal potassium channels

artículo científico publicado en 2015

Atomic determinants of BK channel activation by polyunsaturated fatty acids

artículo científico publicado en 2016

Atomic mutagenesis in ion channels with engineered stoichiometry

artículo científico publicado en 2016

Biophysical costs associated with tetrodotoxin resistance in the sodium channel pore of the garter snake, Thamnophis sirtalis

artículo científico publicado en 2010

Blockade of Permeation by Potassium but Normal Gating of the G628S Nonconducting hERG Channel Mutant ⬇️

artículo científico publicado el 3 de agosto de 2011

Ca2+-dependent excitation-contraction coupling triggered by the heterologous cardiac/brain DHPR beta2a-subunit in skeletal myotubes

artículo científico publicado en 2003

Cellular encoding of Cy dyes for single-molecule imaging.

artículo científico publicado en 2016

Chemical tools for K(+) channel biology

artículo científico publicado en 2009

Conformational dynamics in TRPV1 channels reported by an encoded coumarin amino acid.

artículo científico publicado en 2017

Contributions of conserved residues at the gating interface of glycine receptors.

artículo científico publicado en 2011

Contributions of counter-charge in a potassium channel voltage-sensor domain.

artículo científico publicado en 2011

Cross-kingdom auxiliary subunit modulation of a voltage-gated Sodium channel

artículo científico publicado en 2018

Crystallographic basis for calcium regulation of sodium channels ⬇️

artículo científico publicado el 13 de febrero de 2012

Divergent Cl-and H+ pathways underlie transport coupling and gating in CLC exchangers and channels

scientific article published on 28 April 2020

Engineered transfer RNAs for suppression of premature termination codons

artículo científico publicado en 2019

Expanding Genetic Code Expansion through Resource Facilities, Workshops, and Conferences. ⬇️

artículo científico publicado en 2019

Expression-dependent pharmacology of transient receptor potential vanilloid subtype 1 channels in Xenopus laevis oocytes

artículo científico publicado en 2013

Extracellular quaternary ammonium blockade of transient receptor potential vanilloid subtype 1 channels expressed in Xenopus laevis oocytes.

artículo científico publicado en 2012

HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response.

artículo científico publicado en 2014

Identification and quantification of newly synthesized proteins translationally regulated by YB-1 using a novel Click-SILAC approach.

artículo científico publicado en 2012

Incorporation of Non-Canonical Amino Acids

artículo científico

Intermediate state trapping of a voltage sensor

artículo científico publicado en 2012

Intramembrane charge movements and excitation- contraction coupling expressed by two-domain fragments of the Ca2+ channel.

artículo científico publicado en 2001

Introduction: Applying Chemical Biology to Ion Channels

artículo científico publicado en 2015

Investigating the putative glycine hinge in Shaker potassium channel.

artículo científico publicado en 2005

Involvement of the carboxy-terminus region of the dihydropyridine receptor beta1a subunit in excitation-contraction coupling of skeletal muscle

artículo científico publicado en 1999

Ketamine, at clinical concentrations, does not alter the function of cardiac sarcoplasmic reticulum calcium release channels.

artículo científico publicado en 1995

Local anesthetic inhibition of a bacterial sodium channel

artículo científico publicado en 2012

Main-chain mutagenesis reveals intrahelical coupling in an ion channel voltage-sensor

artículo científico publicado en 2018

Mining Protein Evolution for Insights into Mechanisms of Voltage-Dependent Sodium Channel Auxiliary Subunits

artículo científico publicado en 2018

Modulation of the cardiac sodium channel NaV1.5 by Fyn, a Src family tyrosine kinase.

artículo científico publicado en 2005

Molecular Origin of the L-Type Ca2+ Current of Skeletal Muscle Myotubes Selectively Deficient in Dihydropyridine Receptor β1a Subunit ⬇️

artículo científico publicado el 1 de julio de 1998

Molecular and functional determinants of local anesthetic inhibition of NaChBac.

artículo científico publicado en 2012

Molecular characterization of a two-domain form of the neuronal voltage-gated P/Q-type calcium channel alpha(1)2.1 subunit

artículo científico publicado en 2002

Nη-substituted arginyl peptide inhibitors of protein arginine N-methyltransferases.

artículo científico publicado en 2010

Orthogonality of Pyrrolysine tRNA in the Xenopus oocyte.

artículo científico publicado en 2018

Pharmacological insights and quirks of bacterial sodium channels.

artículo científico publicado en 2014

Rapid evolution of a voltage-gated sodium channel gene in a lineage of electric fish leads to a persistent sodium current

artículo científico publicado en 2018

Removal of Mg2+ inhibition of cardiac ryanodine receptor by palmitoyl coenzyme A

scientific article published on 01 October 1994

Replacing voltage sensor arginines with citrulline provides mechanistic insight into charge versus shape.

artículo científico publicado en 2018

Seeing the Forest through the Trees: towards a Unified View on Physiological Calcium Regulation of Voltage-Gated Sodium Channels ⬇️

artículo científico publicado el 5 de diciembre de 2012

Stirring up controversy with a voltage sensor paddle.

artículo científico publicado en 2004

Structural basis of α-scorpion toxin action on Nav channels

artículo científico publicado en 2019

The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation

artículo científico publicado en 2013

The hitchhiker's guide to the voltage-gated sodium channel galaxy

artículo científico publicado en 2016

The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels in vitro

artículo científico publicado en 2011

The secret lives of voltage sensors.

artículo científico publicado en 2007

Truncation of the carboxyl terminus of the dihydropyridine receptor beta1a subunit promotes Ca2+ dependent excitation-contraction coupling in skeletal myotubes.

artículo científico publicado en 2003

Unnatural amino acids as probes of ligand-receptor interactions and their conformational consequences.

artículo científico

What activates inactivation?

artículo científico publicado en 2013

γ1Subunit Interactions within the Skeletal Muscle L-type Voltage-gated Calcium Channels

artículo científico publicado en 2002

Lista de obras de Christopher A Ahern

A Conserved Residue Cluster That Governs Kinetics of ATP-dependent Gating of Kir6.2 Potassium Channels

A cation-pi interaction between extracellular TEA and an aromatic residue in potassium channels.

A cation-pi interaction discriminates among sodium channels that are either sensitive or resistant to tetrodotoxin block.

A component of excitation-contraction coupling triggered in the absence of the T671-L690 and L720-Q765 regions of the II-III loop of the dihydropyridine receptor alpha(1s) pore subunit.

A novel mechanism for fine-tuning open-state stability in a voltage-gated potassium channel.

An electrostatic interaction between TEA and an introduced pore aromatic drives spring-in-the-door inactivation in Shaker potassium channels

Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains

Atom-by-atom engineering of voltage-gated ion channels: magnified insights into function and pharmacology

Atomic basis for therapeutic activation of neuronal potassium channels

Atomic determinants of BK channel activation by polyunsaturated fatty acids

Atomic mutagenesis in ion channels with engineered stoichiometry

Biophysical costs associated with tetrodotoxin resistance in the sodium channel pore of the garter snake, Thamnophis sirtalis

Blockade of Permeation by Potassium but Normal Gating of the G628S Nonconducting hERG Channel Mutant ⬇️

Ca2+-dependent excitation-contraction coupling triggered by the heterologous cardiac/brain DHPR beta2a-subunit in skeletal myotubes

Cellular encoding of Cy dyes for single-molecule imaging.

Chemical tools for K(+) channel biology

Conformational dynamics in TRPV1 channels reported by an encoded coumarin amino acid.

Contributions of conserved residues at the gating interface of glycine receptors.

Contributions of counter-charge in a potassium channel voltage-sensor domain.

Cross-kingdom auxiliary subunit modulation of a voltage-gated Sodium channel

Crystallographic basis for calcium regulation of sodium channels ⬇️

Divergent Cl-and H+ pathways underlie transport coupling and gating in CLC exchangers and channels

Engineered transfer RNAs for suppression of premature termination codons

Expanding Genetic Code Expansion through Resource Facilities, Workshops, and Conferences. ⬇️

Expression-dependent pharmacology of transient receptor potential vanilloid subtype 1 channels in Xenopus laevis oocytes

Extracellular quaternary ammonium blockade of transient receptor potential vanilloid subtype 1 channels expressed in Xenopus laevis oocytes.

HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response.

Identification and quantification of newly synthesized proteins translationally regulated by YB-1 using a novel Click-SILAC approach.

Incorporation of Non-Canonical Amino Acids

Intermediate state trapping of a voltage sensor

Intramembrane charge movements and excitation- contraction coupling expressed by two-domain fragments of the Ca2+ channel.

Introduction: Applying Chemical Biology to Ion Channels

Investigating the putative glycine hinge in Shaker potassium channel.

Involvement of the carboxy-terminus region of the dihydropyridine receptor beta1a subunit in excitation-contraction coupling of skeletal muscle

Ketamine, at clinical concentrations, does not alter the function of cardiac sarcoplasmic reticulum calcium release channels.

Local anesthetic inhibition of a bacterial sodium channel

Main-chain mutagenesis reveals intrahelical coupling in an ion channel voltage-sensor

Mining Protein Evolution for Insights into Mechanisms of Voltage-Dependent Sodium Channel Auxiliary Subunits

Modulation of the cardiac sodium channel NaV1.5 by Fyn, a Src family tyrosine kinase.

Molecular Origin of the L-Type Ca2+ Current of Skeletal Muscle Myotubes Selectively Deficient in Dihydropyridine Receptor β1a Subunit ⬇️

Molecular and functional determinants of local anesthetic inhibition of NaChBac.

Molecular characterization of a two-domain form of the neuronal voltage-gated P/Q-type calcium channel alpha(1)2.1 subunit

Nη-substituted arginyl peptide inhibitors of protein arginine N-methyltransferases.

Orthogonality of Pyrrolysine tRNA in the Xenopus oocyte.

Pharmacological insights and quirks of bacterial sodium channels.

Rapid evolution of a voltage-gated sodium channel gene in a lineage of electric fish leads to a persistent sodium current

Removal of Mg2+ inhibition of cardiac ryanodine receptor by palmitoyl coenzyme A

Replacing voltage sensor arginines with citrulline provides mechanistic insight into charge versus shape.

Seeing the Forest through the Trees: towards a Unified View on Physiological Calcium Regulation of Voltage-Gated Sodium Channels ⬇️

Stirring up controversy with a voltage sensor paddle.

Structural basis of α-scorpion toxin action on Nav channels

The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation

The hitchhiker's guide to the voltage-gated sodium channel galaxy

The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels in vitro

The secret lives of voltage sensors.

Truncation of the carboxyl terminus of the dihydropyridine receptor beta1a subunit promotes Ca2+ dependent excitation-contraction coupling in skeletal myotubes.

Unnatural amino acids as probes of ligand-receptor interactions and their conformational consequences.

What activates inactivation?

γ1Subunit Interactions within the Skeletal Muscle L-type Voltage-gated Calcium Channels