Lista de obras - Rick Greupink - Dominio Público Uruguay

A Mechanism-Based Population Pharmacokinetic Analysis Assessing the Feasibility of Efavirenz Dose Reduction to 400 mg in Pregnant Women.

artículo científico publicado en 2018

Assessment of Maternal and Fetal Dolutegravir Exposure by Integrating Ex Vivo Placental Perfusion Data and Physiologically-Based Pharmacokinetic Modeling

artículo científico publicado en 2019

Convallatoxin: a new P-glycoprotein substrate

artículo científico publicado en 2014

Corrigendum to 'Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs' [European Journal of Pharmaceutical Sciences 115 (2018) 175-184]

article

Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs

artículo científico publicado en 2018

Differential effects of psychoactive substances on human wildtype and polymorphic T356M dopamine transporters (DAT)

artículo científico publicado en 2019

Drug Dosing in Pregnant Women: Challenges and Opportunities in Using Physiologically Based Pharmacokinetic Modeling and Simulations.

artículo científico publicado en 2018

Drug-drug interactions between rosuvastatin and oral antidiabetic drugs occurring at the level of OATP1B1.

artículo científico publicado en 2012

Editor's Highlight: PlacentalDisposition and Effects of Crizotinib: An Ex Vivo Study in the Isolated Dual-Side Perfused Human Cotyledon.

artículo científico publicado en 2017

Evaluating darunavir/ritonavir dosing regimens for HIV-positive pregnant women using semi-mechanistic pharmacokinetic modelling

scientific article published on 01 May 2019

Experimental study of diclofenac and its biliary metabolites on anastomotic healing

scientific article published on 17 May 2018

Exploiting transport activity of p-glycoprotein at the blood-brain barrier for the development of peripheral cannabinoid type 1 receptor antagonists.

artículo científico publicado en 2012

First reported use of elvitegravir and cobicistat during pregnancy.

artículo científico publicado en 2016

Free dug concentrations in pregnancy: Bound to measure unbound?

artículo científico publicado en 2017

In silico identification and in vitro validation of potential cholestatic compounds through 3D ligand-based pharmacophore modeling of BSEP inhibitors.

artículo científico publicado en 2014

Interaction of digitalis-like compounds with liver uptake transporters NTCP, OATP1B1, and OATP1B3.

artículo científico publicado en 2014

Interaction of fluvastatin with the liver-specific Na+ -dependent taurocholate cotransporting polypeptide (NTCP).

artículo científico publicado en 2011

Interaction of immunosuppressive drugs with human organic anion transporter (OAT) 1 and OAT3, and multidrug resistance-associated protein (MRP) 2 and MRP4.

artículo científico publicado en 2013

Mannose-6-phosphate/insulin-Like growth factor-II receptors may represent a target for the selective delivery of mycophenolic acid to fibrogenic cells.

artículo científico publicado en 2006

Microbial Glucuronidase Inhibition Reduces Severity of Diclofenac-Induced Anastomotic Leak in Rats

artículo científico publicado en 2018

Pharmacokinetics of HIV-Integrase Inhibitors During Pregnancy: Mechanisms, Clinical Implications and Knowledge Gaps

artículo científico publicado en 2019

Pharmacokinetics of a hepatic stellate cell-targeted doxorubicin construct in bile duct-ligated rats

artículo científico publicado en 2006

Pharmacological considerations on the use of antiretrovirals in pregnancy.

artículo científico

Physiologically Based Modelling of Darunavir/Ritonavir Pharmacokinetics During Pregnancy

artículo científico publicado en 2015

Placental disposition of the immunosuppressive drug tacrolimus in renal transplant recipients and in ex vivo perfused placental tissue

artículo científico publicado en 2018

Placental transfer of the HIV integrase inhibitor dolutegravir in an ex vivo human cotyledon perfusion model

artículo científico publicado en 2015

Prediction of Fetal Darunavir Exposure by Integrating Human Ex-Vivo Placental Transfer and Physiologically Based Pharmacokinetic Modeling

artículo científico publicado en 2018

Rat precision-cut liver slices predict drug-induced cholestatic injury

artículo científico publicado en 2017

Review article: direct-acting antivirals for the treatment of HCV during pregnancy and lactation - implications for maternal dosing, foetal exposure, and safety for mother and child

scientific article published on 25 August 2019

Selective targeting of pentoxifylline to hepatic stellate cells using a novel platinum-based linker technology.

artículo científico publicado en 2006

Studies on the targeted delivery of the antifibrogenic compound mycophenolic acid to the hepatic stellate cell.

artículo científico publicado en 2005

Substantially lowered dolutegravir exposure in a treatment-experienced perinatally HIV-1-infected pregnant woman.

artículo científico publicado en 2016

Targeting 15d-prostaglandin J2 to hepatic stellate cells: two options evaluated.

artículo científico publicado en 2007

The antiproliferative drug doxorubicin inhibits liver fibrosis in bile duct-ligated rats and can be selectively delivered to hepatic stellate cells in vivo.

artículo científico publicado en 2006

Therapeutic effects of the mitochondrial ROS-redox modulator KH176 in a mammalian model of Leigh Disease

artículo científico publicado en 2017

Uremic solutes modulate hepatic bile acid handling and induce mitochondrial toxicity

artículo científico publicado en 2019

Lista de obras de Rick Greupink

A Mechanism-Based Population Pharmacokinetic Analysis Assessing the Feasibility of Efavirenz Dose Reduction to 400 mg in Pregnant Women.

Assessment of Maternal and Fetal Dolutegravir Exposure by Integrating Ex Vivo Placental Perfusion Data and Physiologically-Based Pharmacokinetic Modeling

Convallatoxin: a new P-glycoprotein substrate

Corrigendum to 'Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs' [European Journal of Pharmaceutical Sciences 115 (2018) 175-184]

Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs

Differential effects of psychoactive substances on human wildtype and polymorphic T356M dopamine transporters (DAT)

Drug Dosing in Pregnant Women: Challenges and Opportunities in Using Physiologically Based Pharmacokinetic Modeling and Simulations.

Drug-drug interactions between rosuvastatin and oral antidiabetic drugs occurring at the level of OATP1B1.

Editor's Highlight: PlacentalDisposition and Effects of Crizotinib: An Ex Vivo Study in the Isolated Dual-Side Perfused Human Cotyledon.

Evaluating darunavir/ritonavir dosing regimens for HIV-positive pregnant women using semi-mechanistic pharmacokinetic modelling

Experimental study of diclofenac and its biliary metabolites on anastomotic healing

Exploiting transport activity of p-glycoprotein at the blood-brain barrier for the development of peripheral cannabinoid type 1 receptor antagonists.

First reported use of elvitegravir and cobicistat during pregnancy.

Free dug concentrations in pregnancy: Bound to measure unbound?

In silico identification and in vitro validation of potential cholestatic compounds through 3D ligand-based pharmacophore modeling of BSEP inhibitors.

Interaction of digitalis-like compounds with liver uptake transporters NTCP, OATP1B1, and OATP1B3.

Interaction of fluvastatin with the liver-specific Na+ -dependent taurocholate cotransporting polypeptide (NTCP).

Interaction of immunosuppressive drugs with human organic anion transporter (OAT) 1 and OAT3, and multidrug resistance-associated protein (MRP) 2 and MRP4.

Mannose-6-phosphate/insulin-Like growth factor-II receptors may represent a target for the selective delivery of mycophenolic acid to fibrogenic cells.

Microbial Glucuronidase Inhibition Reduces Severity of Diclofenac-Induced Anastomotic Leak in Rats

Pharmacokinetics of HIV-Integrase Inhibitors During Pregnancy: Mechanisms, Clinical Implications and Knowledge Gaps

Pharmacokinetics of a hepatic stellate cell-targeted doxorubicin construct in bile duct-ligated rats

Pharmacological considerations on the use of antiretrovirals in pregnancy.

Physiologically Based Modelling of Darunavir/Ritonavir Pharmacokinetics During Pregnancy

Placental disposition of the immunosuppressive drug tacrolimus in renal transplant recipients and in ex vivo perfused placental tissue

Placental transfer of the HIV integrase inhibitor dolutegravir in an ex vivo human cotyledon perfusion model

Prediction of Fetal Darunavir Exposure by Integrating Human Ex-Vivo Placental Transfer and Physiologically Based Pharmacokinetic Modeling

Rat precision-cut liver slices predict drug-induced cholestatic injury

Review article: direct-acting antivirals for the treatment of HCV during pregnancy and lactation - implications for maternal dosing, foetal exposure, and safety for mother and child

Selective targeting of pentoxifylline to hepatic stellate cells using a novel platinum-based linker technology.

Studies on the targeted delivery of the antifibrogenic compound mycophenolic acid to the hepatic stellate cell.

Substantially lowered dolutegravir exposure in a treatment-experienced perinatally HIV-1-infected pregnant woman.

Targeting 15d-prostaglandin J2 to hepatic stellate cells: two options evaluated.

The antiproliferative drug doxorubicin inhibits liver fibrosis in bile duct-ligated rats and can be selectively delivered to hepatic stellate cells in vivo.

Therapeutic effects of the mitochondrial ROS-redox modulator KH176 in a mammalian model of Leigh Disease

Uremic solutes modulate hepatic bile acid handling and induce mitochondrial toxicity