Lista de obras - Alistair Nichol - Dominio Público Uruguay

A Multicenter Randomized Trial of Atorvastatin Therapy in Intensive Care Patients with Severe Sepsis

artículo científico publicado en 2013

A cluster randomised, crossover, registry-embedded clinical trial of proton pump inhibitors versus histamine-2 receptor blockers for ulcer prophylaxis therapy in the intensive care unit (PEPTIC study): study protocol

artículo científico publicado en 2018

A pilot feasibility trial of allocation of freshest available red blood cells versus standard care in critically ill patients.

artículo científico publicado en 2011

A randomised controlled trial of an open lung strategy with staircase recruitment, titrated PEEP and targeted low airway pressures in patients with acute respiratory distress syndrome.

artículo científico publicado en 2011

A randomised controlled trial of standard transfusion versus fresher red blood cell use in intensive care (TRANSFUSE): protocol and statistical analysis plan

artículo científico publicado en 2014

Advancing preparedness for clinical research during infectious disease epidemics

artículo científico publicado en 2019

Age of red blood cells and mortality in the critically ill.

artículo científico publicado en 2011

Bending the Pandemic Curve: Improving Decision-Making With Clinical Research.

artículo científico publicado en 2018

Biomarker Predictors of Adverse Acute Kidney Injury Outcomes in Critically Ill Patients: The Dublin Acute Biomarker Group Evaluation Study

scientific article published on 14 June 2019

Biomarkers of acute kidney injury in anesthesia, intensive care and major surgery: from the bench to clinical research to clinical practice.

scientific article published on June 2010

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

artículo científico publicado en 2021

Cause and timing of death and sub-group differential effects of erythropoietin in the EPO-TBI study.

artículo científico publicado en 2017

Changes in Temperature Management of Cardiac Arrest Patients Following Publication of the Target Temperature Management Trial*

artículo científico publicado en 2018

Characteristics and Outcomes of Critically Ill Trauma Patients in Australia and New Zealand (2005-2017)

artículo científico publicado en 2020

Comment on Rishu et al. Time required to initiate outbreak and pandemic observational research.

artículo científico publicado en 2017

Cost-Effectiveness of Erythropoietin in Traumatic Brain Injury: A Multinational Trial-Based Economic Analysis

artículo científico publicado en 2019

Critical care services and 2009 H1N1 influenza in Australia and New Zealand.

artículo científico publicado en 2009

Deep vein thrombosis and pulmonary embolus in patients with traumatic brain injury: a prospective observational study.

artículo científico publicado en 2012

Diabetes and Overweight/Obesity Are Independent, Nonadditive Risk Factors for In-Hospital Severity of COVID-19: An International, Multicenter Retrospective Meta-analysis

Dynamic lactate indices as predictors of outcome in critically ill patients.

artículo científico publicado en 2011

Early outcome prediction after severe traumatic brain injury: can multimodal magnetic resonance imaging assist in clinical prognostication for individual patients?

artículo científico publicado el 1 de marzo de 2011

Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial

artículo científico publicado en 2021

Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients With Severe Traumatic Brain Injury: The POLAR Randomized Clinical Trial

scientific article published in The Journal of the American Medical Association

Effect of Stress Ulcer Prophylaxis With Proton Pump Inhibitors vs Histamine-2 Receptor Blockers on In-Hospital Mortality Among ICU Patients Receiving Invasive Mechanical Ventilation: The PEPTIC Randomized Clinical Trial

artículo científico publicado en 2020

Effect of age of red cells for transfusion on patient outcomes: a systematic review and meta-analysis.

artículo científico publicado en 2018

Erythropoiesis-stimulating Agents in Critically Ill Trauma Patients: A Systematic Review and Meta-analysis.

artículo científico publicado en 2016

Erythropoietin as a novel brain and kidney protective agent.

scientific article published on May 2011

Erythropoietin for traumatic brain injury

artículo científico publicado en 2014

Erythropoietin in patients with traumatic brain injury and extracranial injury-A post hoc analysis of the erythropoietin traumatic brain injury trial.

artículo científico

Erythropoietin in traumatic brain injury (EPO-TBI): a double-blind randomised controlled trial.

artículo científico publicado en 2015

Erythropoietin in traumatic brain injury associated acute kidney injury: A randomized controlled trial

scientific article published on 21 August 2018

Erythropoietin in traumatic brain injury: study protocol for a randomised controlled trial

artículo científico publicado en 2015

Erythropoietin to Reduce Mortality in Traumatic Brain Injury: A Post-hoc Dose-effect Analysis.

artículo científico publicado en 2017

Genetic mechanisms of critical illness in Covid-19

scientific article published on 11 December 2020

High-frequency oscillation in acute respiratory distress syndrome: who rescues the rescuer?

scientific article published on 01 June 2007

Hypercapnia and acidosis in sepsis: a double-edged sword?

artículo científico publicado en 2010

Hypothermia in patients with brain injury: the way forward?

Hypoxaemic rescue therapies in acute respiratory distress syndrome: Why, when, what and which one?

artículo científico publicado en 2012

Infection-induced lung injury is worsened after renal buffering of hypercapnic acidosis.

artículo científico publicado en 2009

Inhibition of Rho-kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation.

artículo científico publicado en 2005

Ionized calcium concentration and outcome in critical illness*

article

Is it too early to recommend a restrictive transfusion strategy in critically ill patients with ischemic heart disease?

scientific article published on 01 November 2008

Key stakeholder perceptions about consent to participate in acute illness research: a rapid, systematic review to inform epi/pandemic research preparedness.

artículo científico publicado en 2015

Letter by Bellomo et al Regarding Article, “Relationship Between Supranormal Oxygen Tension and Outcome After Resuscitation From Cardiac Arrest”

artículo científico publicado en 2012

Long-term quality of life in patients with acute respiratory distress syndrome requiring extracorporeal membrane oxygenation for refractory hypoxaemia

artículo científico publicado en 2012

Maximal Recruitment Open Lung Ventilation in Acute Respiratory Distress Syndrome (PHARLAP). A Phase II, Multicenter Randomized Controlled Clinical Trial

artículo científico publicado en 2019

Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials ⬇️

artículo científico

O2, do we know what to do?

scientific article published on 01 December 2019

Open source clinical science for emerging infections

artículo científico publicado en 2014

Pathophysiology of severe traumatic brain injury

scientific article published on 22 May 2018

Permissive Hypercapnia, Alveolar Recruitment and Low Airway Pressure (PHARLAP): a protocol for a phase 2 trial in patients with acute respiratory distress syndrome

scholarly article

Permissive hypercapnia in acute respiratory distress syndrome - is now the time to get strict?

artículo científico publicado el 1 de septiembre de 2011

Priority Needs for Conducting Pandemic-Relevant Clinical Research With Children in Europe: A Consensus Study With Pediatric Clinician-Researchers

artículo científico publicado en 2019

Prophylactic Hypothermia for Severe Traumatic Brain Injury-Reply

scientific article published on 01 May 2019

Prospective observational study of postoperative complications after percutaneous dilatational or surgical tracheostomy in critically ill patients.

artículo científico publicado en 2009

Protocol for a multicentre randomised controlled trial of early and sustained prophylactic hypothermia in the management of traumatic brain injury.

artículo científico publicado en 2015

Reported practice of temperature adjustment (α-stat v pH-stat) for arterial blood gases measurement among investigators from two major cardiac arrest trials

artículo científico publicado en 2019

Statistical analysis plan for the POLAR-RCT: The Prophylactic hypOthermia trial to Lessen trAumatic bRain injury-Randomised Controlled Trial

artículo científico publicado en 2018

Talking to the people that really matter about their participation in pandemic clinical research: A qualitative study in four European countries.

artículo científico publicado en 2017

Targeted hypothermia versus targeted Normothermia after out-of-hospital cardiac arrest (TTM2): A randomized clinical trial-Rationale and design

scientific article published on 26 June 2019

Targeted therapeutic mild hypercapnia after cardiac arrest.

artículo científico publicado en 2017

The Meaning of Acute Kidney Injury and Its Relevance to Intensive Care and Anaesthesia ⬇️

artículo científico publicado el 1 de noviembre de 2012

The NAPRESSIM trial: the use of low-dose, prophylactic naloxone infusion to prevent respiratory depression with intrathecally administered morphine in elective hepatobiliary surgery: a study protocol and statistical analysis plan for a randomised co

artículo científico publicado en 2017

The association between early arterial oxygenation and mortality in ventilated patients with acute ischaemic stroke.

artículo científico publicado en 2012

The effect of a low-dose naloxone infusion on the incidence of respiratory depression after intrathecal morphine administration for major open hepatobiliary surgery: a randomised controlled trial

artículo científico publicado en 2019

The implications of the PEPTIC trial for clinical practice

scientific article published on 01 March 2020

The undiscovered country: therapeutic targeting of carbon dioxide levels in critically ill patients

Therapeutic hypothermia: Benefits, mechanisms and potential clinical applications in neurological, cardiac and kidney injury ⬇️

artículo científico publicado el 9 de abril de 2011

Transfusion practice and guidelines in Australian and New Zealand intensive care units

artículo científico publicado en 2010

Venous thromboembolic events in critically ill traumatic brain injury patients.

artículo científico publicado en 2016

Venous thromboembolism prophylaxis in the critically ill: a point prevalence survey of current practice in Australian and New Zealand intensive care units.

artículo científico publicado en 2010

What the public think about participation in medical research during an influenza pandemic: an international cross-sectional survey

artículo científico publicado en 2019

Who Says There Is No “I” in Team? Achieving Individual Success in Collaborative Clinical Research in Critical Care

scientific article published on 01 October 2016

Whole-genome sequencing reveals host factors underlying critical COVID-19

artículo científico publicado en 2022

Lista de obras de Alistair Nichol

A Multicenter Randomized Trial of Atorvastatin Therapy in Intensive Care Patients with Severe Sepsis

A cluster randomised, crossover, registry-embedded clinical trial of proton pump inhibitors versus histamine-2 receptor blockers for ulcer prophylaxis therapy in the intensive care unit (PEPTIC study): study protocol

A pilot feasibility trial of allocation of freshest available red blood cells versus standard care in critically ill patients.

A randomised controlled trial of an open lung strategy with staircase recruitment, titrated PEEP and targeted low airway pressures in patients with acute respiratory distress syndrome.

A randomised controlled trial of standard transfusion versus fresher red blood cell use in intensive care (TRANSFUSE): protocol and statistical analysis plan

Advancing preparedness for clinical research during infectious disease epidemics

Age of red blood cells and mortality in the critically ill.

Bending the Pandemic Curve: Improving Decision-Making With Clinical Research.

Biomarker Predictors of Adverse Acute Kidney Injury Outcomes in Critically Ill Patients: The Dublin Acute Biomarker Group Evaluation Study

Biomarkers of acute kidney injury in anesthesia, intensive care and major surgery: from the bench to clinical research to clinical practice.

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

Cause and timing of death and sub-group differential effects of erythropoietin in the EPO-TBI study.

Changes in Temperature Management of Cardiac Arrest Patients Following Publication of the Target Temperature Management Trial*

Characteristics and Outcomes of Critically Ill Trauma Patients in Australia and New Zealand (2005-2017)

Comment on Rishu et al. Time required to initiate outbreak and pandemic observational research.

Cost-Effectiveness of Erythropoietin in Traumatic Brain Injury: A Multinational Trial-Based Economic Analysis

Critical care services and 2009 H1N1 influenza in Australia and New Zealand.

Deep vein thrombosis and pulmonary embolus in patients with traumatic brain injury: a prospective observational study.

Diabetes and Overweight/Obesity Are Independent, Nonadditive Risk Factors for In-Hospital Severity of COVID-19: An International, Multicenter Retrospective Meta-analysis

Dynamic lactate indices as predictors of outcome in critically ill patients.

Early outcome prediction after severe traumatic brain injury: can multimodal magnetic resonance imaging assist in clinical prognostication for individual patients?

Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial

Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients With Severe Traumatic Brain Injury: The POLAR Randomized Clinical Trial

Effect of Stress Ulcer Prophylaxis With Proton Pump Inhibitors vs Histamine-2 Receptor Blockers on In-Hospital Mortality Among ICU Patients Receiving Invasive Mechanical Ventilation: The PEPTIC Randomized Clinical Trial

Effect of age of red cells for transfusion on patient outcomes: a systematic review and meta-analysis.

Erythropoiesis-stimulating Agents in Critically Ill Trauma Patients: A Systematic Review and Meta-analysis.

Erythropoietin as a novel brain and kidney protective agent.

Erythropoietin for traumatic brain injury

Erythropoietin in patients with traumatic brain injury and extracranial injury-A post hoc analysis of the erythropoietin traumatic brain injury trial.

Erythropoietin in traumatic brain injury (EPO-TBI): a double-blind randomised controlled trial.

Erythropoietin in traumatic brain injury associated acute kidney injury: A randomized controlled trial

Erythropoietin in traumatic brain injury: study protocol for a randomised controlled trial

Erythropoietin to Reduce Mortality in Traumatic Brain Injury: A Post-hoc Dose-effect Analysis.

Genetic mechanisms of critical illness in Covid-19

High-frequency oscillation in acute respiratory distress syndrome: who rescues the rescuer?

Hypercapnia and acidosis in sepsis: a double-edged sword?

Hypothermia in patients with brain injury: the way forward?

Hypoxaemic rescue therapies in acute respiratory distress syndrome: Why, when, what and which one?

Infection-induced lung injury is worsened after renal buffering of hypercapnic acidosis.

Inhibition of Rho-kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation.

Ionized calcium concentration and outcome in critical illness*

Is it too early to recommend a restrictive transfusion strategy in critically ill patients with ischemic heart disease?

Key stakeholder perceptions about consent to participate in acute illness research: a rapid, systematic review to inform epi/pandemic research preparedness.

Letter by Bellomo et al Regarding Article, “Relationship Between Supranormal Oxygen Tension and Outcome After Resuscitation From Cardiac Arrest”

Long-term quality of life in patients with acute respiratory distress syndrome requiring extracorporeal membrane oxygenation for refractory hypoxaemia

Maximal Recruitment Open Lung Ventilation in Acute Respiratory Distress Syndrome (PHARLAP). A Phase II, Multicenter Randomized Controlled Clinical Trial

Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials ⬇️

O2, do we know what to do?

Open source clinical science for emerging infections

Pathophysiology of severe traumatic brain injury

Permissive Hypercapnia, Alveolar Recruitment and Low Airway Pressure (PHARLAP): a protocol for a phase 2 trial in patients with acute respiratory distress syndrome

Permissive hypercapnia in acute respiratory distress syndrome - is now the time to get strict?

Priority Needs for Conducting Pandemic-Relevant Clinical Research With Children in Europe: A Consensus Study With Pediatric Clinician-Researchers

Prophylactic Hypothermia for Severe Traumatic Brain Injury-Reply

Prospective observational study of postoperative complications after percutaneous dilatational or surgical tracheostomy in critically ill patients.

Protocol for a multicentre randomised controlled trial of early and sustained prophylactic hypothermia in the management of traumatic brain injury.

Reported practice of temperature adjustment (α-stat v pH-stat) for arterial blood gases measurement among investigators from two major cardiac arrest trials

Statistical analysis plan for the POLAR-RCT: The Prophylactic hypOthermia trial to Lessen trAumatic bRain injury-Randomised Controlled Trial

Talking to the people that really matter about their participation in pandemic clinical research: A qualitative study in four European countries.

Targeted hypothermia versus targeted Normothermia after out-of-hospital cardiac arrest (TTM2): A randomized clinical trial-Rationale and design

Targeted therapeutic mild hypercapnia after cardiac arrest.

The Meaning of Acute Kidney Injury and Its Relevance to Intensive Care and Anaesthesia ⬇️

The NAPRESSIM trial: the use of low-dose, prophylactic naloxone infusion to prevent respiratory depression with intrathecally administered morphine in elective hepatobiliary surgery: a study protocol and statistical analysis plan for a randomised co

The association between early arterial oxygenation and mortality in ventilated patients with acute ischaemic stroke.

The effect of a low-dose naloxone infusion on the incidence of respiratory depression after intrathecal morphine administration for major open hepatobiliary surgery: a randomised controlled trial

The implications of the PEPTIC trial for clinical practice

The undiscovered country: therapeutic targeting of carbon dioxide levels in critically ill patients

Therapeutic hypothermia: Benefits, mechanisms and potential clinical applications in neurological, cardiac and kidney injury ⬇️

Transfusion practice and guidelines in Australian and New Zealand intensive care units

Venous thromboembolic events in critically ill traumatic brain injury patients.

Venous thromboembolism prophylaxis in the critically ill: a point prevalence survey of current practice in Australian and New Zealand intensive care units.

What the public think about participation in medical research during an influenza pandemic: an international cross-sectional survey

Who Says There Is No “I” in Team? Achieving Individual Success in Collaborative Clinical Research in Critical Care

Whole-genome sequencing reveals host factors underlying critical COVID-19