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Lista de obras de Lalage M Wakefield

A flexible reporter system for direct observation and isolation of cancer stem cells

artículo científico publicado en 2014

A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis.

artículo científico publicado en 2014

A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFβ signaling in the mammary gland

artículo científico publicado en 2010

A p21-ZEB1 complex inhibits epithelial-mesenchymal transition through the microRNA 183-96-182 cluster.

artículo científico publicado en 2013

Accelerated preclinical testing using transplanted tumors from genetically engineered mouse breast cancer models.

artículo científico publicado en 2007

Acute wounds accelerate tumorigenesis by a T cell-dependent mechanism.

artículo científico publicado en 2008

An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-β in human breast cancer

artículo científico publicado en 2014

Beyond TGFβ: roles of other TGFβ superfamily members in cancer

artículo científico publicado el 1 de mayo de 2013

Bone sialoprotein mediates the tumor cell-targeted prometastatic activity of transforming growth factor beta in a mouse model of breast cancer

artículo científico publicado en 2006

Brightfield proximity ligation assay reveals both canonical and mixed transforming growth factor-β/bone morphogenetic protein Smad signaling complexes in tissue sections.

artículo científico publicado en 2014

Capillary nano-immunoassays: advancing quantitative proteomics analysis, biomarker assessment, and molecular diagnostics

artículo científico publicado en 2015

Chemokine (C-C motif) ligand 2 mediates the prometastatic effect of dysadherin in human breast cancer cells

artículo científico publicado en 2006

Delineating genetic alterations for tumor progression in the MCF10A series of breast cancer cell lines

artículo científico publicado en 2010

Disruption of transforming growth factor beta signaling by a novel ligand-dependent mechanism

artículo científico publicado en 2002

Distribution and modulation of the cellular receptor for transforming growth factor-beta

artículo científico publicado en 1987

Effective chemoimmunotherapy with anti-TGFβ antibody and cyclophosphamide in a mouse model of breast cancer

artículo científico publicado en 2014

Expression of TGF-beta signaling factors in invasive breast cancers: relationships with age at diagnosis and tumor characteristics

artículo científico publicado en 2009

Expression of the B-cell receptor component CD79a on immature myeloid cells contributes to their tumor promoting effects

artículo científico publicado en 2013

Growth differentiation factor-15 encodes a novel microRNA 3189 that functions as a potent regulator of cell death.

artículo científico publicado en 2015

Heterozygous inactivation of TGF-beta1 increases the susceptibility to chemically induced mouse lung tumorigenesis independently of mutational activation of K-ras.

artículo científico publicado en 2001

Identification of the start sites for the 1.9- and 1.4-kb rat transforming growth factor-beta1 transcripts and their effect on translational efficiency.

artículo científico publicado en 1998

Inhibition of the chondrocyte phenotype by retinoic acid involves upregulation of metalloprotease genes independent of TGF-beta

artículo científico publicado en 1994

Isolation of a membrane protein by chromatofocusing: cytochrome b-561 of the adrenal chromaffin granule

scientific article published on 01 September 1984

Keeping order in the neighborhood: new roles for TGFbeta in maintaining epithelial homeostasis

scientific article published on 01 October 2007

Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects

artículo científico publicado en 2002

Modeling metastasis biology and therapy in real time in the mouse lung.

artículo científico publicado en 2010

Peptidylarginine deiminase IV (PADI4) regulates breast cancer stem cells via a novel tumor cell-autonomous suppressor role

artículo científico publicado en 2020

Physicochemical activation of recombinant latent transforming growth factor-beta's 1, 2, and 3

artículo científico publicado en 1990

Progressive tumor formation in mice with conditional deletion of TGF-beta signaling in head and neck epithelia is associated with activation of the PI3K/Akt pathway.

scientific article published on 07 July 2009

Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3

artículo científico publicado en 2017

Quantitation of TGF-β proteins in mouse tissues shows reciprocal changes in TGF-β1 and TGF-β3 in normal vs neoplastic mammary epithelium.

artículo científico

Recharacterization of the start sites for the major human transforming growth factor-beta 1 mRNA

artículo científico publicado en 1997

Reconstitution of the Mg2+ -ATPase of the chromaffin granule membrane

artículo científico publicado el 15 de julio de 1979

Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2.

artículo científico publicado en 2016

SDF-1α mediates wound-promoted tumor growth in a syngeneic orthotopic mouse model of breast cancer.

artículo científico publicado en 2013

TGF-beta 1 prevents hypertrophy of epiphyseal chondrocytes: regulation of gene expression for cartilage matrix proteins and metalloproteases

artículo científico publicado en 1993

TGF-beta signaling in mammary gland development and tumorigenesis.

artículo científico publicado en 2001

TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression.

artículo científico publicado en 2003

TGF-β signaling: positive and negative effects on tumorigenesis

artículo científico publicado el 1 de febrero de 2002

TGF-β-SMAD3 signaling mediates hepatic bile acid and phospholipid metabolism following lithocholic acid-induced liver injury

artículo científico publicado en 2012

Tamoxifen and fenretinide in women with metastatic breast cancer

scientific article published on 01 October 1999

The Outcome of TGFβ Antagonism in Metastatic Breast Cancer Models In Vivo Reflects a Complex Balance between Tumor-Suppressive and Proprogression Activities of TGFβ

scientific article published on 03 October 2019

The recombinant proregion of transforming growth factor beta1 (latency-associated peptide) inhibits active transforming growth factor beta1 in transgenic mice.

scientific article published on June 1996

The role of phospholipids in the modulation of enzyme activities in the chromaffin granule membrane

scientific article published on 01 May 1981

Transforming growth factor-(beta)s and mammary gland involution; functional roles and implications for cancer progression

artículo científico publicado en 2009

Transforming growth factor-beta and breast cancer: Lessons learned from genetically altered mouse models

artículo científico publicado en 2000

Transforming growth factor-beta can suppress tumorigenesis through effects on the putative cancer stem or early progenitor cell and committed progeny in a breast cancer xenograft model

artículo científico publicado en 2007

Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency.

artículo científico publicado en 1998

Transforming growth factor-beta: biological function and chemical structure

artículo científico publicado en 1986

Transforming growth factor-beta: multifunctional regulator of cell growth and phenotype

artículo científico publicado en 1988

Transforming growth factors-beta are not good biomarkers of chemopreventive efficacy in a preclinical breast cancer model system.

artículo científico publicado en 2000

Transient tumor-fibroblast interactions increase tumor cell malignancy by a TGF-Beta mediated mechanism in a mouse xenograft model of breast cancer

artículo científico publicado en 2010

Validation of transgenic mammary cancer models: goals of the NCI Mouse Models of Human Cancer Consortium and the mammary cancer CD-ROM

artículo científico publicado en 2002