Lista de obras - Adam P Roberts - Dominio Público Uruguay

(Inter)nationalising the antibiotic research and development pipeline

scientific article published on 18 November 2019

A helicase-containing module defines a family of pCD630-like plasmids in Clostridium difficile

artículo científico publicado en 2017

A modular master on the move: the Tn916 family of mobile genetic elements.

artículo científico publicado en 2009

A preliminary study investigating the survival of tetracycline resistant Enterococcus faecalis after root canal irrigation with high concentrations of tetracycline.

artículo científico publicado en 2007

A tet(S/M) hybrid from CTn6000 and CTn916 recombination

artículo científico publicado en 2012

AWZ1066S, a highly specific anti- drug candidate for a short-course treatment of filariasis

article published in the Proceedings of the National Academy of Sciences of the United States of America

Acquired antibiotic resistance genes: an overview.

artículo científico publicado en 2011

Analysis of a Clostridium difficile PCR ribotype 078 100 kilobase island reveals the presence of a novel transposon, Tn6164

artículo científico publicado en 2012

Antibiotic Resistance Is Associated with Integrative and Conjugative Elements and Genomic Islands in Naturally Circulating Streptococcus pneumoniae Isolates from Adults in Liverpool, UK

artículo científico publicado en 2020

Antibiotic and antiseptic resistance genes are linked on a novel mobile genetic element: Tn6087.

artículo científico

Capture of a Novel, Antibiotic Resistance Encoding, Mobile Genetic Element from Escherichia coli Using a New Entrapment Vector

artículo científico publicado en 2020

Carbapenemases on the move: it’s good to be on ICEs

artículo científico publicado en 2018

Characterisation of the plasmidome within Enterococcus faecalis isolated from marginal periodontitis patients in Norway.

artículo científico publicado en 2013

Characterization of Tn916S, a Tn916-like element containing the tetracycline resistance determinant tet(S).

artículo científico publicado en 2004

Characterization of tet(32) genes from the oral metagenome.

artículo científico publicado en 2008

Characterization of the conjugative transposon Tn6000 from Enterococcus casseliflavus 664.1H1 (formerly Enterococcus faecium 664.1H1).

artículo científico publicado en 2010

Characterization of the ends and target sites of the novel conjugative transposon Tn5397 from Clostridium difficile: excision and circularization is mediated by the large resolvase, TndX.

artículo científico publicado en 2000

Clostridium difficile: no longer an enigmatic pathogen?

artículo científico publicado en 2010

Co-diversification of Enterococcus faecium Core Genomes and PBP5: Evidences of pbp5 Horizontal Transfer.

artículo científico publicado en 2016

Comment on: Resistance gene naming and numbering: is it a new gene or not?

artículo científico publicado en 2016

Complete genome sequence of BS49 and draft genome sequence of BS34A, Bacillus subtilis strains carrying Tn916

artículo científico publicado en 2015

Complete genome sequence of the Clostridium difficile laboratory strain 630Δerm reveals differences from strain 630, including translocation of the mobile element CTn5.

artículo científico publicado en 2015

Composition and antibiotic resistance profile of microcosm dental plaques before and after exposure to tetracycline.

artículo científico publicado en 2002

Conjugative transfer of the integrative conjugative elements ICESt1 and ICESt3 from Streptococcus thermophilus

artículo científico publicado en 2009

Conserved collateral antibiotic susceptibility networks in diverse clinical strains of Escherichia coli

scientific article published in Nature Communications

DNA sequence of the insertional hot spot of Tn916 in the Clostridium difficile genome and discovery of a Tn916-like element in an environmental isolate integrated in the same hot spot

scientific article published on 01 November 2000

Demonstration that the group II intron from the Clostridial Conjugative transposon Tn5397 undergoes splicing In vivo

article published in 2001

Detection of Novel Integrons in the Metagenome of Human Saliva

artículo científico publicado en 2016

Detection of a Novel, and Likely Ancestral, Tn916-Like Element from a Human Saliva Metagenomic Library

scientific article published on 14 May 2020

Determination of copy number and circularization ratio of Tn-Tn family of conjugative transposons in oral streptococci by droplet digital PCR

artículo científico publicado en 2018

Determination of the attP and attB sites of phage CD27 from Clostridium difficile NCTC 12727.

artículo científico publicado en 2013

Determination of the genetic support for tet(W) in oral bacteria.

artículo científico publicado en 2007

Development of an integrative vector for the expression of antisense RNA in Clostridium difficile.

artículo científico publicado en 2003

Different antibiotic resistance and sporulation properties within multiclonal Clostridium difficile PCR ribotypes 078, 126, and 033 in a single calf farm.

artículo científico publicado en 2012

Distribution of tetracycline and erythromycin resistance genes among human oral and fecal metagenomic DNA.

artículo científico publicado en 2009

Draft Genome Sequence of Eggerthia catenaformis Strain MAR1 Isolated from Saliva of Healthy Humans

artículo científico publicado en 2017

Draft Genome Sequence of the Nontoxigenic Clostridium difficile Strain CD37 ⬇️

artículo científico publicado el 1 de abril de 2012

Drivers of Resistance in Uganda and Malawi (DRUM): a protocol for the evaluation of One-Health drivers of Extended Spectrum Beta Lactamase (ESBL) resistance in Low-Middle Income Countries (LMICs)

artículo científico publicado en 2022

Drivers of Resistance in Uganda and Malawi (DRUM): a protocol for the evaluation of One-Health drivers of Extended Spectrum Beta Lactamase (ESBL) resistance in Low-Middle Income Countries (LMICs)

artículo científico publicado en 2023

Editorial: ICE and Small

artículo científico publicado en 2018

Effect of Environment on the Evolutionary Trajectories and Growth Characteristics of Antibiotic-Resistant Escherichia coli Mutants

scientific article published on 28 August 2019

Evaluation of the antimicrobial effect of super-oxidized water (Sterilox®) and sodium hypochlorite against Enterococcus faecalis in a bovine root canal model ⬇️

artículo científico publicado el 1 de septiembre de 2010

Eﬄux in the Oral Metagenome: The Discovery of a Novel Tetracycline and Tigecycline ABC Transporter.

artículo científico publicado en 2016

From ASH to MGE ⬇️

artículo científico publicado el 1 de mayo de 2011

Gene transfer in bacterial biofilms

artículo científico publicado en 2001

Generation of an erythromycin-sensitive derivative of Clostridium difficile strain 630 (630Deltaerm) and demonstration that the conjugative transposon Tn916DeltaE enters the genome of this strain at multiple sites

scientific article published on 01 February 2005

Genetic organisation, mobility and predicted functions of genes on integrated, mobile genetic elements in sequenced strains of Clostridium difficile.

artículo científico publicado en 2011

Horizontal gene transfer converts non-toxigenic Clostridium difficile strains into toxin producers

artículo científico publicado en 2013

Identification of integrative and conjugative elements in pathogenic and commensal Neisseriaceae species via genomic distributions of DNA uptake sequence dialects

scientific article published on 04 May 2020

In silico analysis of sequenced strains of Clostridium difficile reveals a related set of conjugative transposons carrying a variety of accessory genes.

artículo científico publicado en 2012

Investigating Transfer of Large Chromosomal Regions Containing the Pathogenicity Locus Between Clostridium difficile Strains.

artículo científico publicado en 2016

Investigation of fitness cost, copy number variation and excision rate of Tn916/Tn916-like elements in oral streptococci and enterococci.

artículo científico publicado en 2017

Isolation of an antimicrobial-resistant, biofilm-forming, Klebsiella grimontii isolate from a reusable water bottle

scientific article published on 03 March 2020

Mechanism of integration and excision in conjugative transposons.

artículo científico publicado en 2002

Metagenomic Insights into Transferable Antibiotic Resistance in Oral Bacteria.

artículo científico publicado en 2016

Minocycline resistance in an oral Streptococcus infantis isolate is encoded by tet(S) on a novel small, low copy number plasmid

artículo científico publicado en 2014

Mobile genetic elements in Clostridium difficile and their role in genome function

artículo científico

Mosaic tetracycline resistance genes encoding ribosomal protection proteins

artículo científico publicado en 2016

Multiplex loop-mediated isothermal amplification (multi-LAMP) assay for rapid detection of mcr-1 to mcr-5 in colistin-resistant bacteria

scientific article published on 02 July 2019

Oral biofilms: a reservoir of transferable, bacterial, antimicrobial resistance.

artículo científico publicado en 2010

PCR-based detection of composite transposons and translocatable units from oral metagenomic DNA.

artículo científico publicado en 2016

Piperacillin/tazobactam resistance in a clinical isolate of Escherichia coli due to IS26-mediated amplification of blaTEM-1B

artículo científico publicado en 2020

Piperacillin/tazobactam-resistant, cephalosporin-susceptible Escherichia coli bloodstream infections are driven by multiple acquisition of resistance across diverse sequence types

artículo científico publicado en 2022

Pneumococcal colonization in healthy adult research participants in the conjugate vaccine era, United Kingdom, 2010-2017

article

Potential role of Veillonella spp. as a reservoir of transferable tetracycline resistance in the oral cavity.

artículo científico publicado en 2006

Presence of Type I-F CRISPR/Cas systems is associated with antimicrobial susceptibility in Escherichia coli

artículo científico publicado en 2017

Promoter activity of ORF-less gene cassettes isolated from the oral metagenome.

artículo científico publicado en 2019

Reduced Susceptibility to Antiseptics Is Conferred by Heterologous Housekeeping Genes.

artículo científico publicado en 2017

Reinventing the antimicrobial pipeline in response to the global crisis of antimicrobial-resistant infections

artículo científico publicado en 2019

Revised nomenclature for transposable genetic elements

artículo científico publicado en 2008

Setting the standard: multidisciplinary hallmarks for structural, equitable and tracked antibiotic policy

scientific article published on 01 September 2020

Swab and Send: a citizen science, antibiotic discovery project

artículo científico publicado en 2020

Symbiotic Microbes from Marine Invertebrates: Driving a New Era of Natural Product Drug Discovery

article published in 2017

TetAB46, a predicted heterodimeric ABC transporter conferring tetracycline resistance in Streptococcus australis isolated from the oral cavity.

artículo científico publicado en 2012

The Human Salivary Microbiome Is Shaped by Shared Environment Rather than Genetics: Evidence from a Large Family of Closely Related Individuals.

artículo científico publicado en 2017

The Transposon Registry

scientific article published on 09 October 2019

The evolving epidemic of Clostridium difficile 630

artículo científico publicado en 2018

The impact of horizontal gene transfer on the adaptive ability of the human oral microbiome.

artículo científico publicado en 2014

The impact of horizontal gene transfer on the biology of Clostridium difficile

artículo científico publicado en 2014

The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome

artículo científico publicado en 2006

The shufflon of IncI1 plasmids is rearranged constantly during different growth conditions

artículo científico publicado en 2019

Tn916-like elements from human, oral, commensal streptococci possess a variety of antibiotic and antiseptic resistance genes

scientific article published on 11 February 2012

Transfer of TN916-like elements in microcosm dental plaques.

artículo científico publicado en 2001

Transfer of a conjugative transposon, Tn5397 in a model oral biofilm

scientific article published on 01 August 1999

Transferable Plasmid-Borne mcr-1 in a Colistin-Resistant Shigella flexneri Isolate.

artículo científico publicado en 2018

Transposon mutagenesis in Clostridium difficile.

artículo científico publicado en 2010

Variation on a theme; an overview of the Tn916/Tn1545 family of mobile genetic elements in the oral and nasopharyngeal streptococci.

artículo científico publicado en 2014

Lista de obras de Adam P Roberts

(Inter)nationalising the antibiotic research and development pipeline

A helicase-containing module defines a family of pCD630-like plasmids in Clostridium difficile

A modular master on the move: the Tn916 family of mobile genetic elements.

A preliminary study investigating the survival of tetracycline resistant Enterococcus faecalis after root canal irrigation with high concentrations of tetracycline.

A tet(S/M) hybrid from CTn6000 and CTn916 recombination

AWZ1066S, a highly specific anti- drug candidate for a short-course treatment of filariasis

Acquired antibiotic resistance genes: an overview.

Analysis of a Clostridium difficile PCR ribotype 078 100 kilobase island reveals the presence of a novel transposon, Tn6164

Antibiotic Resistance Is Associated with Integrative and Conjugative Elements and Genomic Islands in Naturally Circulating Streptococcus pneumoniae Isolates from Adults in Liverpool, UK

Antibiotic and antiseptic resistance genes are linked on a novel mobile genetic element: Tn6087.

Capture of a Novel, Antibiotic Resistance Encoding, Mobile Genetic Element from Escherichia coli Using a New Entrapment Vector

Carbapenemases on the move: it’s good to be on ICEs

Characterisation of the plasmidome within Enterococcus faecalis isolated from marginal periodontitis patients in Norway.

Characterization of Tn916S, a Tn916-like element containing the tetracycline resistance determinant tet(S).

Characterization of tet(32) genes from the oral metagenome.

Characterization of the conjugative transposon Tn6000 from Enterococcus casseliflavus 664.1H1 (formerly Enterococcus faecium 664.1H1).

Characterization of the ends and target sites of the novel conjugative transposon Tn5397 from Clostridium difficile: excision and circularization is mediated by the large resolvase, TndX.

Clostridium difficile: no longer an enigmatic pathogen?

Co-diversification of Enterococcus faecium Core Genomes and PBP5: Evidences of pbp5 Horizontal Transfer.

Comment on: Resistance gene naming and numbering: is it a new gene or not?

Complete genome sequence of BS49 and draft genome sequence of BS34A, Bacillus subtilis strains carrying Tn916

Complete genome sequence of the Clostridium difficile laboratory strain 630Δerm reveals differences from strain 630, including translocation of the mobile element CTn5.

Composition and antibiotic resistance profile of microcosm dental plaques before and after exposure to tetracycline.

Conjugative transfer of the integrative conjugative elements ICESt1 and ICESt3 from Streptococcus thermophilus

Conserved collateral antibiotic susceptibility networks in diverse clinical strains of Escherichia coli

DNA sequence of the insertional hot spot of Tn916 in the Clostridium difficile genome and discovery of a Tn916-like element in an environmental isolate integrated in the same hot spot

Demonstration that the group II intron from the Clostridial Conjugative transposon Tn5397 undergoes splicing In vivo

Detection of Novel Integrons in the Metagenome of Human Saliva

Detection of a Novel, and Likely Ancestral, Tn916-Like Element from a Human Saliva Metagenomic Library

Determination of copy number and circularization ratio of Tn-Tn family of conjugative transposons in oral streptococci by droplet digital PCR

Determination of the attP and attB sites of phage CD27 from Clostridium difficile NCTC 12727.

Determination of the genetic support for tet(W) in oral bacteria.

Development of an integrative vector for the expression of antisense RNA in Clostridium difficile.

Different antibiotic resistance and sporulation properties within multiclonal Clostridium difficile PCR ribotypes 078, 126, and 033 in a single calf farm.

Distribution of tetracycline and erythromycin resistance genes among human oral and fecal metagenomic DNA.

Draft Genome Sequence of Eggerthia catenaformis Strain MAR1 Isolated from Saliva of Healthy Humans

Draft Genome Sequence of the Nontoxigenic Clostridium difficile Strain CD37 ⬇️

Drivers of Resistance in Uganda and Malawi (DRUM): a protocol for the evaluation of One-Health drivers of Extended Spectrum Beta Lactamase (ESBL) resistance in Low-Middle Income Countries (LMICs)

Drivers of Resistance in Uganda and Malawi (DRUM): a protocol for the evaluation of One-Health drivers of Extended Spectrum Beta Lactamase (ESBL) resistance in Low-Middle Income Countries (LMICs)

Editorial: ICE and Small

Effect of Environment on the Evolutionary Trajectories and Growth Characteristics of Antibiotic-Resistant Escherichia coli Mutants

Evaluation of the antimicrobial effect of super-oxidized water (Sterilox®) and sodium hypochlorite against Enterococcus faecalis in a bovine root canal model ⬇️

Eﬄux in the Oral Metagenome: The Discovery of a Novel Tetracycline and Tigecycline ABC Transporter.

From ASH to MGE ⬇️

Gene transfer in bacterial biofilms

Generation of an erythromycin-sensitive derivative of Clostridium difficile strain 630 (630Deltaerm) and demonstration that the conjugative transposon Tn916DeltaE enters the genome of this strain at multiple sites

Genetic organisation, mobility and predicted functions of genes on integrated, mobile genetic elements in sequenced strains of Clostridium difficile.

Horizontal gene transfer converts non-toxigenic Clostridium difficile strains into toxin producers

Identification of integrative and conjugative elements in pathogenic and commensal Neisseriaceae species via genomic distributions of DNA uptake sequence dialects

In silico analysis of sequenced strains of Clostridium difficile reveals a related set of conjugative transposons carrying a variety of accessory genes.

Investigating Transfer of Large Chromosomal Regions Containing the Pathogenicity Locus Between Clostridium difficile Strains.

Investigation of fitness cost, copy number variation and excision rate of Tn916/Tn916-like elements in oral streptococci and enterococci.

Isolation of an antimicrobial-resistant, biofilm-forming, Klebsiella grimontii isolate from a reusable water bottle

Mechanism of integration and excision in conjugative transposons.

Metagenomic Insights into Transferable Antibiotic Resistance in Oral Bacteria.

Minocycline resistance in an oral Streptococcus infantis isolate is encoded by tet(S) on a novel small, low copy number plasmid

Mobile genetic elements in Clostridium difficile and their role in genome function

Mosaic tetracycline resistance genes encoding ribosomal protection proteins

Multiplex loop-mediated isothermal amplification (multi-LAMP) assay for rapid detection of mcr-1 to mcr-5 in colistin-resistant bacteria

Oral biofilms: a reservoir of transferable, bacterial, antimicrobial resistance.

PCR-based detection of composite transposons and translocatable units from oral metagenomic DNA.

Piperacillin/tazobactam resistance in a clinical isolate of Escherichia coli due to IS26-mediated amplification of blaTEM-1B

Piperacillin/tazobactam-resistant, cephalosporin-susceptible Escherichia coli bloodstream infections are driven by multiple acquisition of resistance across diverse sequence types

Pneumococcal colonization in healthy adult research participants in the conjugate vaccine era, United Kingdom, 2010-2017

Potential role of Veillonella spp. as a reservoir of transferable tetracycline resistance in the oral cavity.

Presence of Type I-F CRISPR/Cas systems is associated with antimicrobial susceptibility in Escherichia coli

Promoter activity of ORF-less gene cassettes isolated from the oral metagenome.

Reduced Susceptibility to Antiseptics Is Conferred by Heterologous Housekeeping Genes.

Reinventing the antimicrobial pipeline in response to the global crisis of antimicrobial-resistant infections

Revised nomenclature for transposable genetic elements

Setting the standard: multidisciplinary hallmarks for structural, equitable and tracked antibiotic policy

Swab and Send: a citizen science, antibiotic discovery project

Symbiotic Microbes from Marine Invertebrates: Driving a New Era of Natural Product Drug Discovery

TetAB46, a predicted heterodimeric ABC transporter conferring tetracycline resistance in Streptococcus australis isolated from the oral cavity.

The Human Salivary Microbiome Is Shaped by Shared Environment Rather than Genetics: Evidence from a Large Family of Closely Related Individuals.

The Transposon Registry

The evolving epidemic of Clostridium difficile 630

The impact of horizontal gene transfer on the adaptive ability of the human oral microbiome.

The impact of horizontal gene transfer on the biology of Clostridium difficile