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Lista de obras de Alice Vrielink

A hydrogen-bonding network is important for oxidation and isomerization in the reaction catalyzed by cholesterol oxidase

artículo científico publicado en 2009

A missense mutation sheds light on a novel structure-function relationship of RANKL

scientific article published on 23 September 2020

A novel type of regulation of the vimentin intermediate filament cytoskeleton by a Golgi protein

scientific journal article

Acquisition of the capsule locus by horizontal gene transfer in Neisseria meningitidis is often accompanied by the loss of UDP-GalNAc synthesis

artículo científico publicado en 2017

An extended N-H bond, driven by a conserved second-order interaction, orients the flavin N5 orbital in cholesterol oxidase

artículo científico publicado en 2017

Atomic resolution density maps reveal secondary structure dependent differences in electronic distribution

artículo científico publicado en 2003

Binding and channeling of alternative substrates in the enzyme DmpFG: a molecular dynamics study.

artículo científico publicado en 2014

Biological channeling of a reactive intermediate in the bifunctional enzyme DmpFG.

artículo científico publicado en 2012

Cholesterol oxidase: ultrahigh-resolution crystal structure and multipolar atom model-based analysis

artículo científico publicado en 2015

Cholesterol oxidases: a study of nature's approach to protein design

artículo científico publicado en 2003

Computational insights for the hydride transfer and distinctive roles of key residues in cholesterol oxidase

artículo científico publicado en 2017

Computational site-directed mutagenesis studies of the role of the hydrophobic triad on substrate binding in cholesterol oxidase.

artículo científico publicado en 2017

Conformational flexibility of EptA driven by an interdomain helix provides insights for enzyme-substrate recognition

artículo científico publicado en 2021

Conserved and novel functions for Arabidopsis thaliana MIA40 in assembly of proteins in mitochondria and peroxisomes

artículo científico publicado en 2010

Crystal structure of LAAO from Calloselasma rhodostoma with an L-phenylalanine substrate: insights into structure and mechanism

artículo científico publicado en 2006

Crystallization and preliminary X-ray analysis of cholesterol oxidase from Brevibacterium sterolicum containing covalently bound FAD

scientific article published on 01 March 1996

Crystallization and preliminary X-ray analysis of dmpFG-encoded 4-hydroxy-2-ketovalerate aldolase--aldehyde dehydrogenase (acylating) from Pseudomonas sp. strain CF600.

artículo científico publicado en 2001

Crystallization and preliminary X-ray analysis of the formiminotransferase domain from the bifunctional enzyme formiminotransferase-cyclodeaminase

artículo científico publicado en 1999

Crystallization and preliminary diffraction analysis of an engineered cephalosporin acylase.

artículo científico publicado en 2010

Detergents in Membrane Protein Purification and Crystallisation.

artículo científico publicado en 2016

Direct demonstration of lipid phosphorylation in the lipid bilayer of the biomimetic bicontinuous cubic phase using the confined enzyme lipid A phosphoethanolamine transferase.

artículo científico publicado en 2017

Distortion of flavin geometry is linked to ligand binding in cholesterol oxidase

artículo científico publicado en 2007

ESR and electron nuclear double resonance characterization of the cholesterol oxidase from Brevibacterium sterolicum in its semiquinone state.

artículo científico publicado en 1994

Editorial overview: Catalysis and regulation: Structural features guiding enzyme catalysed processes

scientific article published on 01 December 2018

Electron spin echo envelope modulation studies of the semiquinone anion radical of cholesterol oxidase from Brevibacterium sterolicum

artículo científico publicado en 1997

Enzyme targets for drug design of new anti-virulence therapeutics

scientific article published on 14 September 2018

Exploring ligand recognition, selectivity and dynamics of TPR domains of chloroplast Toc64 and mitochondria Om64 fromArabidopsis thaliana

article

High-resolution structures of cholesterol oxidase in the reduced state provide insights into redox stabilization

artículo científico publicado en 2014

Ligand recognition by the TPR domain of the import factor Toc64 from Arabidopsis thaliana

artículo científico publicado en 2013

Mechanism of the dehydrogenase reaction of DmpFG and analysis of inter-subunit channeling efficiency and thermodynamic parameters in the overall reaction

artículo científico publicado en 2013

Molecular features of the copper binding sites in the octarepeat domain of the prion protein

artículo científico publicado en 2002

Oxidation of cysteine 34 of plasma albumin as a biomarker of oxidative stress

artículo científico publicado en 2020

Oxygen access to the active site of cholesterol oxidase through a narrow channel is gated by an Arg-Glu pair

artículo científico publicado en 2001

PPARα and PPARγ activation is associated with pleural mesothelioma invasion but therapeutic inhibition is ineffective

scientific article published in 2022

Preliminary studies into the inhibition of the cholesterol alpha-glucosyltransferase from Helicobacter pylori using azasugars

scientific article published on 04 March 2010

Production and characterization of recombinant perdeuterated cholesterol oxidase

artículo científico publicado en 2015

Structural and functional studies of a NADP(+)-specific aldehyde dehydrogenase from the luminescent marine bacterium Vibrio harveyi

artículo científico publicado en 1997

Structure and function of lipid A-modifying enzymes

artículo científico publicado en 2019

Structure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activity

artículo científico publicado en 2013

Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding

artículo científico publicado en 2017

Structure-Function Relationships of the Neisserial EptA Enzyme Responsible for Phosphoethanolamine Decoration of Lipid A: Rationale for Drug Targeting

artículo científico publicado en 2018

Sub-Angstrom resolution enzyme X-ray structures: is seeing believing?

artículo científico publicado en 2003

Sub-atomic resolution crystal structure of cholesterol oxidase: what atomic resolution crystallography reveals about enzyme mechanism and the role of the FAD cofactor in redox activity

artículo científico publicado en 2003

The Binding and Release of Oxygen and Hydrogen Peroxide Are Directed by a Hydrophobic Tunnel in Cholesterol Oxidase †

artículo científico publicado en 2008

The Design and Structure of Outer Membrane Receptors from Peroxisomes, Mitochondria, and Chloroplasts

artículo científico publicado en 2015

The first transcriptomes from field-collected individual whiteflies (Bemisia tabaci, Hemiptera: Aleyrodidae)

The role of oxidoreductases in determining the function of the neisserial lipid A phosphoethanolamine transferase required for resistance to polymyxin.

artículo científico publicado en 2014

The yeast transcription elongation factor Spt4/5 is a sequence-specific RNA binding protein

artículo científico publicado en 2016

Thermosensitive mutants of the MPTP and hPTP1B protein tyrosine phosphatases: isolation and structural analysis.

artículo científico publicado en 1996

Ubiquitin fusion constructs allow the expression and purification of multi-KOW domain complexes of the Saccharomyces cerevisiae transcription elongation factor Spt4/5.

artículo científico publicado en 2014