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Lista de obras de Carlos M Farinha

A comparison of 14 antibodies for the biochemical detection of the cystic fibrosis transmembrane conductance regulator protein.

artículo científico publicado en 2004

Analysis of genomic CFTR DNA.

artículo científico publicado en 2004

Antibodies for CFTR studies.

artículo científico publicado en 2004

BAG-1 stabilizes mutant F508del-CFTR in a ubiquitin-like-domain-dependent manner

artículo científico publicado en 2012

Biochemical methods to assess CFTR expression and membrane localization

article

CFTR mutations altering CFTR fragmentation

artículo científico publicado en 2013

Characterization of novel airway submucosal gland cell models for cystic fibrosis studies

artículo científico publicado en 2005

Contribution of casein kinase 2 and spleen tyrosine kinase to CFTR trafficking and protein kinase A-induced activity.

artículo científico publicado en 2011

Control of cystic fibrosis transmembrane conductance regulator membrane trafficking: not just from the endoplasmic reticulum to the Golgi

artículo científico publicado en 2013

EPAC1 activation by cAMP stabilizes CFTR at the membrane by promoting its interaction with NHERF1.

artículo científico publicado en 2016

Folding Status Is Determinant over Traffic-Competence in Defining CFTR Interactors in the Endoplasmic Reticulum.

artículo científico publicado en 2019

From the endoplasmic reticulum to the plasma membrane: mechanisms of CFTR folding and trafficking

artículo científico publicado en 2016

Full Rescue of F508del-CFTR Processing and Function by CFTR Modulators Can Be Achieved by Removal of Two Regulatory Regions

artículo científico publicado en 2020

Improved Fmoc-solid-phase peptide synthesis of an extracellular loop of CFTR for antibody selection by the phage display technology

scientific article published on 12 May 2020

Increased efficacy of VX-809 in different cellular systems results from an early stabilization effect of F508del-CFTR.

artículo científico publicado en 2015

Investigating Alternative Transport of Integral Plasma Membrane Proteins from the ER to the Golgi: Lessons from the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).

artículo científico publicado en 2016

LMTK2-mediated phosphorylation regulates CFTR endocytosis in human airway epithelial cells

artículo científico publicado en 2014

Measurements of Functional Responses in Human Primary Lung Cells as a Basis for Personalized Therapy for Cystic Fibrosis.

artículo científico publicado en 2014

Mechanical Properties of Human Bronchial Epithelial Cells Expressing Wt- and Mutant CFTR

artículo científico publicado en 2020

Methods for RNA extraction, cDNA preparation and analysis of CFTR transcripts.

artículo científico publicado en 2004

Most F508del-CFTR is targeted to degradation at an early folding checkpoint and independently of calnexin

artículo científico publicado en 2005

Partial rescue of F508del-CFTR channel gating with modest improvement of protein processing, but not stability by a dual-acting small molecule

artículo científico publicado en 2018

Post-translational modifications of CFTR: insight into protein trafficking and cystic fibrosis disease.

artículo científico publicado en 2013

Protein and lipid interactions - Modulating CFTR trafficking and rescue.

artículo científico publicado en 2017

Proteomic interaction profiling reveals KIFC1 as a factor involved in early targeting of F508del-CFTR to degradation

artículo científico publicado en 2018

Rab GTPases regulate the trafficking of channels and transporters - a focus on cystic fibrosis.

artículo científico publicado en 2017

Regulation of ENaC biogenesis by the stress response protein SERP1.

artículo científico publicado en 2012

Revertants, low temperature, and correctors reveal the mechanism of F508del-CFTR rescue by VX-809 and suggest multiple agents for full correction.

artículo científico publicado en 2013

Solubilizing Mutations Used to Crystallize One CFTR Domain Attenuate the Trafficking and Channel Defects Caused by the Major Cystic Fibrosis Mutation

artículo científico publicado en 2008

Targeting of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Protein with a Technetium-99m Imaging Probe

artículo científico publicado en 2018

Teaching biochemistry at Lisbon University-Facing the challenge of the Bologna Declaration in the 25th anniversary of the biochemistry course

artículo científico publicado en 2007

The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70

artículo científico publicado en 2002

Unusually common cystic fibrosis mutation in Portugal encodes a misprocessed protein.

artículo científico publicado en 2003