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Lista de obras de Anne M Filppula

Autoinhibition of CYP3A4 leads to important role of CYP2C8 in imatinib metabolism: variability in CYP2C8 activity may alter plasma concentrations and response

artículo científico publicado en 2012

Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions .

artículo científico publicado en 2017

Critical Differences between Enzyme Sources in Sensitivity to Detect Time-Dependent Inactivation of CYP2C8

artículo científico publicado en 2019

Gemfibrozil impairs imatinib absorption and inhibits the CYP2C8-mediated formation of its main metabolite.

artículo científico publicado en 2013

Gemfibrozil markedly increases the plasma concentrations of montelukast: a previously unrecognized role for CYP2C8 in the metabolism of montelukast

artículo científico publicado en 2010

Glucuronidation Converts Clopidogrel to a Strong Time-Dependent Inhibitor of CYP2C8: A Phase II Metabolite as a Perpetrator of Drug–Drug Interactions

artículo científico publicado en 2014

Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations

scientific article published on 10 April 2019

In vitro assessment of time-dependent inhibitory effects on CYP2C8 and CYP3A activity by fourteen protein kinase inhibitors

artículo científico publicado en 2014

Neurotoxicity and low paclitaxel clearance associated with concomitant clopidogrel therapy in a 60-year-old Caucasian woman with ovarian carcinoma

artículo científico publicado en 2015

Potent mechanism-based inhibition of CYP3A4 by imatinib explains its liability to interact with CYP3A4 substrates.

artículo científico publicado en 2012

Reevaluation of the Microsomal Metabolism of Montelukast: Major Contribution by CYP2C8 at Clinically Relevant Concentrations

scientific article published on 02 February 2011

Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions

artículo científico

Ticagrelor Increases Exposure to the Breast Cancer Resistance Protein Substrate Rosuvastatin

artículo científico publicado en 2023

Validation and development of MTH1 inhibitors for treatment of cancer.

artículo científico publicado en 2016

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