Lista de obras - Giovanna Musco - Dominio Público Uruguay

2-Deoxy-d-Glucose Ameliorates PKD Progression

artículo científico publicado en 2015

2D TR-NOESY experiments interrogate and rank ligand-receptor interactions in living human cancer cells

artículo científico publicado en 2010

A critical assessment of force field accuracy against NMR data for cyclic peptides containing β-amino acids

scientific article published on 01 June 2018

A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA.

artículo científico publicado en 2007

A persulfidation-based mechanism controls aquaporin-8 conductance.

artículo científico publicado en 2018

A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent

artículo científico publicado en 2018

A stapled chromogranin A-derived peptide is a potent dual ligand for integrins αvβ6 and αvβ8

artículo científico publicado en 2019

AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome

artículo científico publicado en 2012

An easy way to include weak alignment constraints into NMR structure calculations.

artículo científico publicado en 2001

Assessing Heterogeneity of Osteolytic Lesions in Multiple Myeloma by ¹H HR-MAS NMR Metabolomics

scientific article published on 31 October 2016

Assignment of the 1H, 15N, and 13C resonances of the C-terminal domain of frataxin, the protein responsible for Friedreich ataxia

article

Backbone and side-chain (1)H, (15)N, (13)C assignment and secondary structure of BPSL1445 from Burkholderia pseudomallei.

artículo científico publicado en 2015

Binding modes of the distamycin analogue FCE-24517 to d(CGTATACG)2.1H and13C sequence-specific assignments

Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy.

artículo científico publicado en 2013

Diflunisal targets the HMGB1/CXCL12 heterocomplex and blocks immune cell recruitment

artículo científico publicado en 2019

Dissecting intrinsic and ligand-induced structural communication in the β3 headpiece of integrins.

artículo científico publicado en 2017

Effects of pathological mutations on the stability of a conserved amino acid triad in retinoschisin

artículo científico publicado en 2003

Exploring PHD Fingers and H3K4me0 Interactions with Molecular Dynamics Simulations and Binding Free Energy Calculations: AIRE-PHD1, a Comparative Study ⬇️

artículo científico publicado el 15 de octubre de 2012

Flexible vs Rigid Epitope Conformations for Diagnostic- and Vaccine-Oriented Applications: Novel Insights from the Burkholderia pseudomallei BPSL2765 Pal3 Epitope.

artículo científico publicado en 2016

Friedreich's ataxia protein: phylogenetic evidence for mitochondrial dysfunction

article

Glycyrrhizin binds to high-mobility group box 1 protein and inhibits its cytokine activities

artículo científico publicado en 2007

HMGB1 as biomarker and drug target.

artículo científico publicado en 2016

HMGB1-carbenoxolone interactions: dynamics insights from combined nuclear magnetic resonance and molecular dynamics.

artículo científico publicado en 2011

Identification of TMPRSS6 cleavage sites of hemojuvelin

artículo científico publicado en 2015

Identification of a novel de novo deletion in RAF1 associated with biventricular hypertrophy in Noonan syndrome.

artículo científico publicado en 2014

Integrating a prospective pilot trial and patient-derived xenografts to trace metabolic changes associated with acute myeloid leukemia

artículo científico publicado en 2016

Interactions of the C2 domain of human factor V with a model membrane

artículo científico publicado en 2006

Mechanism of Action of the Tumor Vessel Targeting Agent NGR-hTNF: Role of Both NGR Peptide and hTNF in Cell Binding and Signaling

scientific article published on 12 September 2019

Metabolic determinants of the immune modulatory function of neural stem cells

artículo científico publicado en 2016

Metabolomics of B to plasma cell differentiation

artículo científico publicado en 2011

Metadynamics Simulations Rationalise the Conformational Effects Induced by N-Methylation of RGD Cyclic Hexapeptides

artículo científico publicado en 2015

Molecular Dynamics Reveal that isoDGR-Containing Cyclopeptides Are True αvβ3 Antagonists Unable To Promote Integrin Allostery and Activation

scholarly article by Michela Ghitti et al published 20 June 2012 in Angewandte Chemie International Edition

NMR and computational methods in the structural and dynamic characterization of ligand-receptor interactions.

artículo científico publicado en 2014

NMR structure of the first PHD finger of autoimmune regulator protein (AIRE1). Insights into autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) disease

artículo científico publicado en 2005

Nephrocystin-1 forms a complex with polycystin-1 via a polyproline motif/SH3 domain interaction and regulates the apoptotic response in mammals

artículo científico publicado en 2010

New Insights into Cooperative Binding of Homeodomain Transcription Factors PREP1 and PBX1 to DNA.

artículo científico publicado en 2017

Oxidation-induced structural changes of ceruloplasmin foster NGR motif deamidation that promotes integrin binding and signaling

artículo científico publicado en 2013

PHD finger of autoimmune regulator: an epigenetic link between the histone modifications and tissue-specific antigen expression in thymus

artículo científico publicado en 2008

Partially folded structure of monomeric bovine β-lactoglobulin

artículo científico publicado en 1996

Probing the interaction of a quercetin bioconjugate with Bcl-2 in living human cancer cells with in-cell NMR spectroscopy

scientific article published on 29 September 2018

SP140L, an Evolutionarily Recent Member of the SP100 Family, Is an Autoantigen in Primary Biliary Cirrhosis

artículo científico publicado en 2015

Safety and efficacy of transcranial direct current stimulation in acute experimental ischemic stroke

artículo científico publicado en 2013

Sp140 is a multi-SUMO-1 target and its PHD finger promotes SUMOylation of the adjacent Bromodomain

scientific article published on 19 November 2018

Structural and biochemical characterization of an RNA/DNA binding motif in the N-terminal domain of RecQ4 helicases

artículo científico publicado en 2016

Structural basis for PHDVC5HCHNSD1-C2HRNizp1 interaction: implications for Sotos syndrome.

artículo científico publicado en 2016

Structural basis for the interaction of isoDGR with the RGD-binding site of alphavbeta3 integrin

artículo científico publicado en 2008

Structural properties of Gerstmann-Straussler-Scheinker disease amyloid protein.

artículo científico publicado en 2003

Structure of human Sp140 PHD finger: an atypical fold interacting with Pin1

artículo científico publicado en 2014

Structure-based design of a B cell antigen from B. pseudomallei

artículo científico publicado en 2015

Succinimide-Based Conjugates Improve IsoDGR Cyclopeptide Affinity to αvβ3 without Promoting Integrin Allosteric Activation

artículo científico publicado en 2018

The CCPN Metabolomics Project: a fast protocol for metabolite identification by 2D-NMR

scientific article published on 06 January 2011

The KH module has an αβ fold

scientific article published on 01 January 1995

The Long Acidic Tail of High Mobility Group Box 1 (HMGB1) Protein Forms an Extended and Flexible Structure That Interacts with Specific Residues within and between the HMG Boxes†

artículo científico publicado en 2004

The N-Terminal Domain of NPHP1 Folds into a Monomeric Left-Handed Antiparallel Three-Stranded Coiled Coil with Anti-apoptotic Function

scientific article published on 05 August 2019

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

artículo científico publicado en 2008

The binding domain of the HMGB1 inhibitor carbenoxolone: Theory and experiment

The biophysical and biochemical properties of the autoimmune regulator (AIRE) protein

artículo científico publicado en 2014

The ribonuclease DIS3 promotes let-7 miRNA maturation by degrading the pluripotency factor LIN28B mRNA.

artículo científico publicado en 2015

The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation

artículo científico publicado en 2009

The stem cell secretome and its role in brain repair

artículo científico publicado en 2013

Towards a structural understanding of Friedreich's ataxia: the solution structure of frataxin

artículo científico publicado en 2000

Use of Metadynamics in the Design of isoDGR-Based αvβ3 Antagonists To Fine-Tune the Conformational Ensemble

artículo científico publicado en 2011

dMM-PBSA: A New HADDOCK Scoring Function for Protein-Peptide Docking

artículo científico publicado en 2016

mTORC1 Upregulation Leads to Accumulation of the Oncometabolite Fumarate in a Mouse Model of Renal Cell Carcinoma

artículo científico publicado en 2018

¹H, ¹³C, ¹⁵N backbone and side chain NMR resonance assignments of BPSL1050 from Burkholderia pseudomallei

artículo científico publicado en 2013

Lista de obras de Giovanna Musco

2-Deoxy-d-Glucose Ameliorates PKD Progression

2D TR-NOESY experiments interrogate and rank ligand-receptor interactions in living human cancer cells

A critical assessment of force field accuracy against NMR data for cyclic peptides containing β-amino acids

A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA.

A persulfidation-based mechanism controls aquaporin-8 conductance.

A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent

A stapled chromogranin A-derived peptide is a potent dual ligand for integrins αvβ6 and αvβ8

AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome

An easy way to include weak alignment constraints into NMR structure calculations.

Assessing Heterogeneity of Osteolytic Lesions in Multiple Myeloma by ¹H HR-MAS NMR Metabolomics

Assignment of the 1H, 15N, and 13C resonances of the C-terminal domain of frataxin, the protein responsible for Friedreich ataxia

Backbone and side-chain (1)H, (15)N, (13)C assignment and secondary structure of BPSL1445 from Burkholderia pseudomallei.

Binding modes of the distamycin analogue FCE-24517 to d(CGTATACG)2.1H and13C sequence-specific assignments

Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy.

Diflunisal targets the HMGB1/CXCL12 heterocomplex and blocks immune cell recruitment

Dissecting intrinsic and ligand-induced structural communication in the β3 headpiece of integrins.

Effects of pathological mutations on the stability of a conserved amino acid triad in retinoschisin

Exploring PHD Fingers and H3K4me0 Interactions with Molecular Dynamics Simulations and Binding Free Energy Calculations: AIRE-PHD1, a Comparative Study ⬇️

Flexible vs Rigid Epitope Conformations for Diagnostic- and Vaccine-Oriented Applications: Novel Insights from the Burkholderia pseudomallei BPSL2765 Pal3 Epitope.

Friedreich's ataxia protein: phylogenetic evidence for mitochondrial dysfunction

Glycyrrhizin binds to high-mobility group box 1 protein and inhibits its cytokine activities

HMGB1 as biomarker and drug target.

HMGB1-carbenoxolone interactions: dynamics insights from combined nuclear magnetic resonance and molecular dynamics.

Identification of TMPRSS6 cleavage sites of hemojuvelin

Identification of a novel de novo deletion in RAF1 associated with biventricular hypertrophy in Noonan syndrome.

Integrating a prospective pilot trial and patient-derived xenografts to trace metabolic changes associated with acute myeloid leukemia

Interactions of the C2 domain of human factor V with a model membrane

Mechanism of Action of the Tumor Vessel Targeting Agent NGR-hTNF: Role of Both NGR Peptide and hTNF in Cell Binding and Signaling

Metabolic determinants of the immune modulatory function of neural stem cells

Metabolomics of B to plasma cell differentiation

Metadynamics Simulations Rationalise the Conformational Effects Induced by N-Methylation of RGD Cyclic Hexapeptides

Molecular Dynamics Reveal that isoDGR-Containing Cyclopeptides Are True αvβ3 Antagonists Unable To Promote Integrin Allostery and Activation

NMR and computational methods in the structural and dynamic characterization of ligand-receptor interactions.

NMR structure of the first PHD finger of autoimmune regulator protein (AIRE1). Insights into autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) disease

Nephrocystin-1 forms a complex with polycystin-1 via a polyproline motif/SH3 domain interaction and regulates the apoptotic response in mammals

New Insights into Cooperative Binding of Homeodomain Transcription Factors PREP1 and PBX1 to DNA.

Oxidation-induced structural changes of ceruloplasmin foster NGR motif deamidation that promotes integrin binding and signaling

PHD finger of autoimmune regulator: an epigenetic link between the histone modifications and tissue-specific antigen expression in thymus

Partially folded structure of monomeric bovine β-lactoglobulin

Probing the interaction of a quercetin bioconjugate with Bcl-2 in living human cancer cells with in-cell NMR spectroscopy

SP140L, an Evolutionarily Recent Member of the SP100 Family, Is an Autoantigen in Primary Biliary Cirrhosis

Safety and efficacy of transcranial direct current stimulation in acute experimental ischemic stroke

Sp140 is a multi-SUMO-1 target and its PHD finger promotes SUMOylation of the adjacent Bromodomain

Structural and biochemical characterization of an RNA/DNA binding motif in the N-terminal domain of RecQ4 helicases

Structural basis for PHDVC5HCHNSD1-C2HRNizp1 interaction: implications for Sotos syndrome.

Structural basis for the interaction of isoDGR with the RGD-binding site of alphavbeta3 integrin

Structural properties of Gerstmann-Straussler-Scheinker disease amyloid protein.

Structure of human Sp140 PHD finger: an atypical fold interacting with Pin1

Structure-based design of a B cell antigen from B. pseudomallei

Succinimide-Based Conjugates Improve IsoDGR Cyclopeptide Affinity to αvβ3 without Promoting Integrin Allosteric Activation

The CCPN Metabolomics Project: a fast protocol for metabolite identification by 2D-NMR

The KH module has an αβ fold

The Long Acidic Tail of High Mobility Group Box 1 (HMGB1) Protein Forms an Extended and Flexible Structure That Interacts with Specific Residues within and between the HMG Boxes†

The N-Terminal Domain of NPHP1 Folds into a Monomeric Left-Handed Antiparallel Three-Stranded Coiled Coil with Anti-apoptotic Function

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

The binding domain of the HMGB1 inhibitor carbenoxolone: Theory and experiment

The biophysical and biochemical properties of the autoimmune regulator (AIRE) protein

The ribonuclease DIS3 promotes let-7 miRNA maturation by degrading the pluripotency factor LIN28B mRNA.

The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation

The stem cell secretome and its role in brain repair

Towards a structural understanding of Friedreich's ataxia: the solution structure of frataxin

Use of Metadynamics in the Design of isoDGR-Based αvβ3 Antagonists To Fine-Tune the Conformational Ensemble

dMM-PBSA: A New HADDOCK Scoring Function for Protein-Peptide Docking

mTORC1 Upregulation Leads to Accumulation of the Oncometabolite Fumarate in a Mouse Model of Renal Cell Carcinoma

¹H, ¹³C, ¹⁵N backbone and side chain NMR resonance assignments of BPSL1050 from Burkholderia pseudomallei