Lista de obras - Sara Iachettini - Dominio Público Uruguay

A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds

artículo científico publicado en 2015

Aromatic core extension in the series of N-cyclic bay-substituted perylene G-quadruplex ligands: increased telomere damage, antitumor activity, and strong selectivity for neoplastic over healthy cells

artículo científico publicado en 2012

Erratum: identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities

artículo científico publicado en 2015

Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis

artículo científico publicado en 2013

Evidence for G-quadruplex in the promoter of VEGFR-2 and its targeting to inhibit tumor angiogenesis.

artículo científico publicado en 2014

High-sensitive cardiac troponin T (hs-cTnT) assay as serum biomarker to predict cardiac risk in myotonic dystrophy: A case-control study.

artículo científico publicado en 2016

Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities

artículo científico publicado en 2014

Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein

artículo científico publicado en 2019

N-cyclic bay-substituted perylene G-quadruplex ligands have selective antiproliferative effects on cancer cells and induce telomere damage

artículo científico publicado en 2011

On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts

scientific article published on 19 September 2013

Perylene and coronene derivatives binding to G-rich promoter oncogene sequences efficiently reduce their expression in cancer cells

artículo científico publicado en 2016

Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells

artículo científico publicado en 2018

Receptor and post-receptor abnormalities contribute to insulin resistance in myotonic dystrophy type 1 and type 2 skeletal muscle.

artículo científico publicado en 2017

SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.

artículo científico publicado en 2016

Shooting for Selective Druglike G-Quadruplex Binders: Evidence for Telomeric DNA Damage and Tumor Cell Death

article

Tailoring a lead-like compound targeting multiple G-quadruplex structures

scientific article published on 27 November 2018

Tibialis anterior muscle needle biopsy and sensitive biomolecular methods: a useful tool in myotonic dystrophy type 1

artículo científico publicado en 2015

Lista de obras de Sara Iachettini

A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds

Aromatic core extension in the series of N-cyclic bay-substituted perylene G-quadruplex ligands: increased telomere damage, antitumor activity, and strong selectivity for neoplastic over healthy cells

Erratum: identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities

Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis

Evidence for G-quadruplex in the promoter of VEGFR-2 and its targeting to inhibit tumor angiogenesis.

High-sensitive cardiac troponin T (hs-cTnT) assay as serum biomarker to predict cardiac risk in myotonic dystrophy: A case-control study.

Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities

Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein

N-cyclic bay-substituted perylene G-quadruplex ligands have selective antiproliferative effects on cancer cells and induce telomere damage

On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts

Perylene and coronene derivatives binding to G-rich promoter oncogene sequences efficiently reduce their expression in cancer cells

Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells

Receptor and post-receptor abnormalities contribute to insulin resistance in myotonic dystrophy type 1 and type 2 skeletal muscle.

SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.

Shooting for Selective Druglike G-Quadruplex Binders: Evidence for Telomeric DNA Damage and Tumor Cell Death

Tailoring a lead-like compound targeting multiple G-quadruplex structures

Tibialis anterior muscle needle biopsy and sensitive biomolecular methods: a useful tool in myotonic dystrophy type 1