Lista de obras - Adam J Mead - Dominio Público Uruguay

A British Society for Haematology Guideline on the diagnosis and management of chronic myeloid leukaemia

artículo científico publicado en 2020

A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors.

artículo científico publicado en 2016

A human fetal liver-derived infant MLL-AF4 acute lymphoblastic leukemia model reveals a distinct fetal gene expression program

artículo científico publicado en 2021

Acute myeloid leukaemia blast cells with a tyrosine kinase domain mutation of FLT3 are less sensitive to lestaurtinib than those with a FLT3 internal tandem duplication

artículo científico publicado en 2008

Adult idiopathic thrombocytopenic purpura

artículo científico publicado en 2003

Allogeneic stem cell transplantation for myelofibrosis in 2012.

artículo científico

Application of single-cell genomics in cancer: promise and challenges

artículo científico publicado en 2015

CD34+CD19−CD22+ B-cell progenitors may underlie phenotypic escape in patients treated with CD19-directed therapies

artículo científico publicado en 2022

Canonical Notch signaling is dispensible for adult steady-state and stress myelo-erythropoiesis

artículo científico publicado en 2018

Cell-extrinsic hematopoietic impact of Ezh2 inactivation in fetal liver endothelial cells

Clinical potential of pacritinib in the treatment of myelofibrosis

artículo científico publicado en 2015

Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia

scientific article published on 01 January 2011

Conflicting data on the prognostic significance of FLT3/TKD mutations in acute myeloid leukemia might be related to the incidence of biallelic disease

artículo científico publicado en 2008

Dicer is selectively important for the earliest stages of erythroid development.

artículo científico publicado en 2012

Distinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing.

scientific article published on 04 April 2016

Episomal amplification of NUP214-ABL1 fusion gene in B-cell acute lymphoblastic leukemia.

artículo científico publicado en 2012

Equivalence of BCSH and WHO diagnostic criteria for ET.

artículo científico publicado en 2017

Equivalence of BCSH and WHO diagnostic criteria for ET.

artículo científico publicado en 2016

Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate

artículo científico publicado en 2014

Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors

artículo científico publicado en 2018

Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors

artículo científico publicado en 2021

FLT3 tyrosine kinase domain mutations are biologically distinct from and have a significantly more favorable prognosis than FLT3 internal tandem duplications in patients with acute myeloid leukemia

artículo científico publicado en 2007

FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors

artículo científico publicado en 2013

Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms

artículo científico publicado en 2015

Genetically distinct leukemic stem cells in human CD34- acute myeloid leukemia are arrested at a hemopoietic precursor-like stage.

artículo científico publicado en 2016

Guideline for the diagnosis and management of myelofibrosis.

artículo científico publicado en 2012

Guideline for the investigation and management of eosinophilia.

artículo científico publicado en 2017

HLA-mismatched unrelated donors are a viable alternate graft source for allogeneic transplantation following alemtuzumab-based reduced-intensity conditioning

artículo científico publicado en 2010

Hippocampal and cortical G protein (Gsα, Goα and Gi2α) mRNA expression after electroconvulsive shock or lithium carbonate treatment

artículo científico publicado en 1996

Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation

scientific journal article

Impact of isolated germline JAK2V617I mutation on human hematopoiesis

artículo científico publicado en 2013

In utero origin of myelofibrosis presenting in adult monozygotic twins

scientific article published on 30 May 2022

Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors

artículo científico publicado en 2016

Lymphomyeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cells

artículo científico publicado en 2013

Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program.

artículo científico publicado en 2017

Modification of British Committee for Standards in Haematology diagnostic criteria for essential thrombocythaemia

artículo científico publicado en 2014

Molecular and cellular effects of oncogene cooperation in a genetically accurate AML mouse model

artículo científico publicado en 2012

Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.

artículo científico publicado en 2014

Myeloproliferative neoplasm stem cells.

artículo científico publicado en 2017

Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation.

artículo científico publicado en 2017

Pacritinib versus best available therapy for the treatment of myelofibrosis irrespective of baseline cytopenias (PERSIST-1): an international, randomised, phase 3 trial

artículo científico publicado en 2017

Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia

artículo científico publicado en 2020

Persistent malignant stem cells in del(5q) myelodysplasia in remission

artículo científico publicado en 2010

Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21

artículo científico publicado en 2012

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.

artículo científico publicado en 2013

Practical management of patients with myelofibrosis receiving ruxolitinib

artículo científico publicado en 2013

Real-world tyrosine kinase inhibitor treatment pathways, monitoring patterns and responses in patients with chronic myeloid leukaemia in the United Kingdom: the UK TARGET CML study

scientific article published on 24 May 2020

Response to ruxolitinib in patients with intermediate-1-, intermediate-2-, and high-risk myelofibrosis: results of the UK ROBUST Trial

artículo científico publicado en 2015

Ruxolitinib is effective in patients with intermediate-1 risk myelofibrosis: a summary of recent evidence

artículo científico publicado en 2016

Ruxolitinib vs best available therapy for ET intolerant or resistant to hydroxycarbamide.

artículo científico publicado en 2017

Single cell analysis of normal and leukemic hematopoiesis

artículo científico publicado en 2017

Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells

artículo científico publicado en 2016

Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways

artículo científico publicado en 2016

Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia

artículo científico publicado en 2017

Spliceosome mutations are common in persons with myeloproliferative neoplasm-associated myelofibrosis with RBC-transfusion-dependence and correlate with response to pomalidomide

scientific article published on 07 August 2020

Studying epigenomics in single cells: what is feasible and what can we learn?

scientific article published on 08 December 2015

The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential

artículo científico publicado en 2012

The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia

artículo científico publicado en 2008

Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease

artículo científico publicado en 2019

Use of JAK inhibitors in the management of myelofibrosis: a revision of the British Committee for Standards in Haematology Guidelines for Investigation and Management of Myelofibrosis 2012.

artículo científico publicado en 2014

VALERIE: Visual-based inspection of alternative splicing events at single-cell resolution

artículo científico publicado en 2020

Lista de obras de Adam J Mead

A British Society for Haematology Guideline on the diagnosis and management of chronic myeloid leukaemia

A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors.

A human fetal liver-derived infant MLL-AF4 acute lymphoblastic leukemia model reveals a distinct fetal gene expression program

Acute myeloid leukaemia blast cells with a tyrosine kinase domain mutation of FLT3 are less sensitive to lestaurtinib than those with a FLT3 internal tandem duplication

Adult idiopathic thrombocytopenic purpura

Allogeneic stem cell transplantation for myelofibrosis in 2012.

Application of single-cell genomics in cancer: promise and challenges

CD34+CD19−CD22+ B-cell progenitors may underlie phenotypic escape in patients treated with CD19-directed therapies

Canonical Notch signaling is dispensible for adult steady-state and stress myelo-erythropoiesis

Cell-extrinsic hematopoietic impact of Ezh2 inactivation in fetal liver endothelial cells

Clinical potential of pacritinib in the treatment of myelofibrosis

Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia

Conflicting data on the prognostic significance of FLT3/TKD mutations in acute myeloid leukemia might be related to the incidence of biallelic disease

Dicer is selectively important for the earliest stages of erythroid development.

Distinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing.

Episomal amplification of NUP214-ABL1 fusion gene in B-cell acute lymphoblastic leukemia.

Equivalence of BCSH and WHO diagnostic criteria for ET.

Equivalence of BCSH and WHO diagnostic criteria for ET.

Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate

Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors

Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors

FLT3 tyrosine kinase domain mutations are biologically distinct from and have a significantly more favorable prognosis than FLT3 internal tandem duplications in patients with acute myeloid leukemia

FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors

Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms

Genetically distinct leukemic stem cells in human CD34- acute myeloid leukemia are arrested at a hemopoietic precursor-like stage.

Guideline for the diagnosis and management of myelofibrosis.

Guideline for the investigation and management of eosinophilia.

HLA-mismatched unrelated donors are a viable alternate graft source for allogeneic transplantation following alemtuzumab-based reduced-intensity conditioning

Hippocampal and cortical G protein (Gsα, Goα and Gi2α) mRNA expression after electroconvulsive shock or lithium carbonate treatment

Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation

Impact of isolated germline JAK2V617I mutation on human hematopoiesis

In utero origin of myelofibrosis presenting in adult monozygotic twins

Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors

Lymphomyeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cells

Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program.

Modification of British Committee for Standards in Haematology diagnostic criteria for essential thrombocythaemia

Molecular and cellular effects of oncogene cooperation in a genetically accurate AML mouse model

Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo

Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.

Myeloproliferative neoplasm stem cells.

Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation.

Pacritinib versus best available therapy for the treatment of myelofibrosis irrespective of baseline cytopenias (PERSIST-1): an international, randomised, phase 3 trial

Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia

Persistent malignant stem cells in del(5q) myelodysplasia in remission

Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.

Practical management of patients with myelofibrosis receiving ruxolitinib

Real-world tyrosine kinase inhibitor treatment pathways, monitoring patterns and responses in patients with chronic myeloid leukaemia in the United Kingdom: the UK TARGET CML study

Response to ruxolitinib in patients with intermediate-1-, intermediate-2-, and high-risk myelofibrosis: results of the UK ROBUST Trial

Ruxolitinib is effective in patients with intermediate-1 risk myelofibrosis: a summary of recent evidence

Ruxolitinib vs best available therapy for ET intolerant or resistant to hydroxycarbamide.

Single cell analysis of normal and leukemic hematopoiesis

Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells

Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways

Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia

Spliceosome mutations are common in persons with myeloproliferative neoplasm-associated myelofibrosis with RBC-transfusion-dependence and correlate with response to pomalidomide

Studying epigenomics in single cells: what is feasible and what can we learn?

The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential

The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia

Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease

Use of JAK inhibitors in the management of myelofibrosis: a revision of the British Committee for Standards in Haematology Guidelines for Investigation and Management of Myelofibrosis 2012.

VALERIE: Visual-based inspection of alternative splicing events at single-cell resolution