Lista de obras - Ramon Arens - Dominio Público Uruguay

'Reverse evolution' in T cell biology

artículo científico publicado en 2020

: A workflow for visual and quantitative analysis of flow and mass cytometry data to discover immune signatures and correlations

artículo científico publicado en 2018

A flexible MHC class I multimer loading system for large-scale detection of antigen-specific T cells.

artículo científico publicado en 2018

A poly-neoantigen DNA vaccine synergizes with PD-1 blockade to induce T cell-mediated tumor control

scientific article published on 02 September 2019

A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2 infection

artículo científico publicado en 2022

Adenoviral vaccines promote protective tissue-resident memory T cell populations against cancer

scientific article published on 01 December 2020

Autocrine IL-2 is required for secondary population expansion of CD8+ memory T cells ⬇️

artículo científico publicado el 31 de julio de 2011

B Cell-Specific Expression of B7-2 Is Required for Follicular Th Cell Function in Response to Vaccinia Virus ⬇️

artículo científico publicado el 25 de marzo de 2011

B7-mediated costimulation of CD4 T cells constrains cytomegalovirus persistence ⬇️

artículo científico publicado el 27 de octubre de 2010

CD27-CD70 costimulation controls T cell immunity during acute and persistent cytomegalovirus infection.

artículo científico publicado en 2013

CD70-driven costimulation induces survival or Fas-mediated apoptosis of T cells depending on antigenic load.

artículo científico publicado en 2012

CD8+ T Cells Protect During Vein Graft Disease Development

scientific article published on 13 June 2019

Controlled local delivery of CTLA-4 blocking antibody induces CD8+ T-cell-dependent tumor eradication and decreases risk of toxic side effects.

artículo científico publicado en 2013

Cutting edge: murine cytomegalovirus induces a polyfunctional CD4 T cell response

artículo científico publicado en 2008

Cytomegalovirus infection and progressive differentiation of effector-memory T cells

Demarcated thresholds of tumor-specific CD8 T cells elicited by MCMV-based vaccine vectors provide robust correlates of protection

artículo científico publicado en 2019

Enhanced CD8 T cell responses through GITR-mediated costimulation resolve chronic viral infection.

artículo científico publicado en 2015

Host genetics and tumor environment determine the functional impact of neutrophils in mouse tumor models

scientific article published on 01 September 2020

Identification of a neo-epitope dominating endogenous CD8 T cell responses to MC-38 colorectal cancer

scientific article published on 13 October 2019

Immunotherapy for persistent viral infections and associated disease ⬇️

artículo científico publicado el 10 de enero de 2011

Inhibition of 14q32 microRNA miR-495 reduces lesion formation, intimal hyperplasia and plasma cholesterol levels in experimental restenosis.

artículo científico publicado en 2017

Lack of myeloid cell infiltration as an acquired resistance strategy to immunotherapy

artículo científico publicado en 2020

Local Activation of CD8 T Cells and Systemic Tumor Eradication without Toxicity via Slow Release and Local Delivery of Agonistic CD40 Antibody ⬇️

artículo científico publicado el 9 de marzo de 2011

Local targets for immune therapy to cancer: Tumor draining lymph nodes and tumor microenvironment ⬇️

artículo científico publicado el 16 de agosto de 2012

Lysine acetyltransferase PCAF is a key regulator of arteriogenesis.

artículo científico publicado en 2013

Murine cytomegalovirus (CMV) infection via the intranasal route offers a robust model of immunity upon mucosal CMV infection.

artículo científico publicado en 2015

New approaches in vaccine-based immunotherapy for human papillomavirus-induced cancer.

artículo científico

P300/CBP Associated Factor (PCAF) Deficiency Enhances Diet-Induced Atherosclerosis in ApoE3<sup>*</sup>Leiden Mice via Systemic Inhibition of Regulatory T Cells

artículo científico publicado en 2020

PD-L1 blockade engages tumor-infiltrating lymphocytes to co-express targetable activating and inhibitory receptors

artículo científico publicado en 2019

Peptide Processing Is Critical for T-Cell Memory Inflation and May Be Optimized to Improve Immune Protection by CMV-Based Vaccine Vectors

artículo científico publicado en 2016

Peripheral and systemic antigens elicit an expandable pool of resident memory CD8+ T cells in the bone marrow

artículo científico publicado en 2019

Polyfunctional CD4+ T cell responses to immunodominant epitopes correlate with disease activity of virulent Salmonella

artículo científico publicado en 2012

Predicting the efficacy of cancer vaccines by evaluating T-cell responses ⬇️

artículo científico publicado el 1 de enero de 2013

Prospects of combinatorial synthetic peptide vaccine-based immunotherapy against cancer

artículo científico publicado en 2013

Protective CD8 T cell memory is impaired during chronic CD70-driven costimulation.

artículo científico publicado en 2009

T RM maintenance is regulated by tissue damage via P2RX7

scientific article published on 01 December 2018

T cell co-stimulation and co-inhibition in cardiovascular disease: a double-edged sword

artículo científico publicado en 2019

The Breadth of Synthetic Long Peptide Vaccine-Induced CD8+ T Cell Responses Determines the Efficacy against Mouse Cytomegalovirus Infection.

artículo científico publicado en 2016

The CD4+ T-cell help signal is transmitted from APC to CD8+ T-cells via CD27–CD70 interactions ⬇️

artículo científico publicado el 10 de julio de 2012

The Contribution of Cytomegalovirus Infection to Immune Senescence Is Set by the Infectious Dose.

artículo científico publicado en 2017

The Quantity of Autocrine IL-2 Governs the Expansion Potential of CD8+ T Cells

artículo científico publicado en 2015

The TNFR family members OX40 and CD27 link viral virulence to protective T cell vaccines in mice ⬇️

artículo científico publicado el 22 de diciembre de 2010

The curious case of IL-33 in homeostasis and infection

artículo científico publicado en 2020

The hallmarks of CMV-specific CD8 T-cell differentiation

artículo científico publicado en 2019

The viral context instructs the redundancy of costimulatory pathways in driving CD8(+) T cell expansion.

artículo científico publicado en 2015

Therapeutic Peptide Vaccine-Induced CD8 T Cells Strongly Modulate Intratumoral Macrophages Required for Tumor Regression.

artículo científico publicado en 2015

Therapeutic cancer vaccines

artículo científico publicado en 2015

Tissue-resident memory CD8+ T cells shape local and systemic secondary T cell responses

artículo científico publicado en 2020

Tumor Eradication by Cisplatin Is Sustained by CD80/86-Mediated Costimulation of CD8+ T Cells

artículo científico publicado en 2016

Uncoupling DNA damage from chromatin damage to detoxify doxorubicin

scientific article published on 17 June 2020

Vaccines for established cancer: overcoming the challenges posed by immune evasion

artículo científico publicado en 2016

Viral Persistence Induces Antibody Inflation without Altering Antibody Avidity

artículo científico publicado en 2016

Lista de obras de Ramon Arens

'Reverse evolution' in T cell biology

: A workflow for visual and quantitative analysis of flow and mass cytometry data to discover immune signatures and correlations

A flexible MHC class I multimer loading system for large-scale detection of antigen-specific T cells.

A poly-neoantigen DNA vaccine synergizes with PD-1 blockade to induce T cell-mediated tumor control

A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2 infection

Adenoviral vaccines promote protective tissue-resident memory T cell populations against cancer

Autocrine IL-2 is required for secondary population expansion of CD8+ memory T cells ⬇️

B Cell-Specific Expression of B7-2 Is Required for Follicular Th Cell Function in Response to Vaccinia Virus ⬇️

B7-mediated costimulation of CD4 T cells constrains cytomegalovirus persistence ⬇️

CD27-CD70 costimulation controls T cell immunity during acute and persistent cytomegalovirus infection.

CD70-driven costimulation induces survival or Fas-mediated apoptosis of T cells depending on antigenic load.

CD8+ T Cells Protect During Vein Graft Disease Development

Controlled local delivery of CTLA-4 blocking antibody induces CD8+ T-cell-dependent tumor eradication and decreases risk of toxic side effects.

Cutting edge: murine cytomegalovirus induces a polyfunctional CD4 T cell response

Cytomegalovirus infection and progressive differentiation of effector-memory T cells

Demarcated thresholds of tumor-specific CD8 T cells elicited by MCMV-based vaccine vectors provide robust correlates of protection

Enhanced CD8 T cell responses through GITR-mediated costimulation resolve chronic viral infection.

Host genetics and tumor environment determine the functional impact of neutrophils in mouse tumor models

Identification of a neo-epitope dominating endogenous CD8 T cell responses to MC-38 colorectal cancer

Immunotherapy for persistent viral infections and associated disease ⬇️

Inhibition of 14q32 microRNA miR-495 reduces lesion formation, intimal hyperplasia and plasma cholesterol levels in experimental restenosis.

Lack of myeloid cell infiltration as an acquired resistance strategy to immunotherapy

Local Activation of CD8 T Cells and Systemic Tumor Eradication without Toxicity via Slow Release and Local Delivery of Agonistic CD40 Antibody ⬇️

Local targets for immune therapy to cancer: Tumor draining lymph nodes and tumor microenvironment ⬇️

Lysine acetyltransferase PCAF is a key regulator of arteriogenesis.

Murine cytomegalovirus (CMV) infection via the intranasal route offers a robust model of immunity upon mucosal CMV infection.

New approaches in vaccine-based immunotherapy for human papillomavirus-induced cancer.

P300/CBP Associated Factor (PCAF) Deficiency Enhances Diet-Induced Atherosclerosis in ApoE3<sup>*</sup>Leiden Mice via Systemic Inhibition of Regulatory T Cells

PD-L1 blockade engages tumor-infiltrating lymphocytes to co-express targetable activating and inhibitory receptors

Peptide Processing Is Critical for T-Cell Memory Inflation and May Be Optimized to Improve Immune Protection by CMV-Based Vaccine Vectors

Peripheral and systemic antigens elicit an expandable pool of resident memory CD8+ T cells in the bone marrow

Polyfunctional CD4+ T cell responses to immunodominant epitopes correlate with disease activity of virulent Salmonella

Predicting the efficacy of cancer vaccines by evaluating T-cell responses ⬇️

Prospects of combinatorial synthetic peptide vaccine-based immunotherapy against cancer

Protective CD8 T cell memory is impaired during chronic CD70-driven costimulation.

T RM maintenance is regulated by tissue damage via P2RX7

T cell co-stimulation and co-inhibition in cardiovascular disease: a double-edged sword

The Breadth of Synthetic Long Peptide Vaccine-Induced CD8+ T Cell Responses Determines the Efficacy against Mouse Cytomegalovirus Infection.

The CD4+ T-cell help signal is transmitted from APC to CD8+ T-cells via CD27–CD70 interactions ⬇️

The Contribution of Cytomegalovirus Infection to Immune Senescence Is Set by the Infectious Dose.

The Quantity of Autocrine IL-2 Governs the Expansion Potential of CD8+ T Cells

The TNFR family members OX40 and CD27 link viral virulence to protective T cell vaccines in mice ⬇️

The curious case of IL-33 in homeostasis and infection

The hallmarks of CMV-specific CD8 T-cell differentiation

The viral context instructs the redundancy of costimulatory pathways in driving CD8(+) T cell expansion.

Therapeutic Peptide Vaccine-Induced CD8 T Cells Strongly Modulate Intratumoral Macrophages Required for Tumor Regression.

Therapeutic cancer vaccines

Tissue-resident memory CD8+ T cells shape local and systemic secondary T cell responses

Tumor Eradication by Cisplatin Is Sustained by CD80/86-Mediated Costimulation of CD8+ T Cells

Uncoupling DNA damage from chromatin damage to detoxify doxorubicin

Vaccines for established cancer: overcoming the challenges posed by immune evasion

Viral Persistence Induces Antibody Inflation without Altering Antibody Avidity