Lista de obras - Jean-Claude Sirard - Dominio Público Uruguay

A Toll-Like Receptor 5 Agonist Improves the Efficacy of Antibiotics in Treatment of Primary and Influenza Virus-Associated Pneumococcal Mouse Infections.

artículo científico publicado en 2015

A key role of dendritic cells in probiotic functionality

artículo científico publicado en 2007

A rapid, simple and sensitive liquid chromatography tandem mass spectrometry assay to determine amoxicillin concentrations in biological matrix of little volume

artículo científico publicado en 2019

Activation of Type 3 innate lymphoid cells and interleukin 22 secretion in the lungs during Streptococcus pneumoniae infection

artículo científico publicado en 2014

Adhesin-dependent binding and uptake of Salmonella enterica serovar Typhimurium by dendritic cells.

artículo científico publicado en 2007

Airway structural cells regulate TLR5-mediated mucosal adjuvant activity.

artículo científico publicado en 2013

Alteration of Flt3-Ligand-dependent de novo generation of conventional dendritic cells during influenza infection contributes to respiratory bacterial superinfection

scholarly article published by Mohamad Bachar Ismail in 2018

Antigen delivery by attenuated Bacillus anthracis: new prospects in veterinary vaccines

artículo científico publicado en 1999

Attenuated poxviruses expressing a synthetic HIV protein stimulate HLA-A2-restricted cytotoxic T-cell responses

artículo científico publicado en 2004

Bacillus anthracis pXO1 virulence plasmid encodes a type 1 DNA topoisomerase

artículo científico publicado en 1994

Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa

artículo científico publicado en 2004

Boosting the IL-22 response using Flagellin prevents bacterial infection in cigarette smoke-exposed mice

scientific article published on 23 April 2020

Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection

artículo científico publicado en 2021

Characterization of a plasmid region involved in Bacillus anthracis toxin production and pathogenesis

artículo científico publicado en 2000

Characterization of structural and immunological properties of a fusion protein between flagellin from Salmonella and lumazine synthase from Brucella.

artículo científico publicado en 2017

Characterization of the Bacillus anthracis S-layer: cloning and sequencing of the structural gene

artículo científico publicado en 1995

Characterization of the protective immune response to Yersinia pseudotuberculosis infection in mice vaccinated with an LcrV-secreting strain of Lactococcus lactis

artículo científico publicado en 2016

Compartmentalized Antimicrobial Defenses in Response to Flagellin.

artículo científico publicado en 2017

Delayed expansion and contraction of CD8+ T cell response during infection with virulent Salmonella typhimurium

artículo científico publicado en 2006

Deletion of flagellin's hypervariable region abrogates antibody-mediated neutralization and systemic activation of TLR5-dependent immunity.

artículo científico publicado en 2008

Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo.

artículo científico publicado en 2006

Dendritic cells: the host Achille's heel for mucosal pathogens?

artículo científico publicado en 2004

Early Protection against Pertussis Induced by Live Attenuated Bordetella pertussis BPZE1 Depends on TLR4

artículo científico publicado en 2019

Entry and survival of Salmonella typhimurium in dendritic cells and presentation of recombinant antigens do not require macrophage-specific virulence factors

artículo científico publicado en 2000

Exploration of Bacterial Bottlenecks and Streptococcus pneumoniae Pathogenesis by CRISPRi-Seq

artículo científico publicado en 2020

Exposure to Bacterial CpG DNA Protects from Airway Allergic Inflammation by Expanding Regulatory Lung Interstitial Macrophages.

artículo científico publicado en 2017

Flagellin promotes myeloid differentiation factor 88-dependent development of Th2-type response

artículo científico publicado en 2004

Flagellin stimulation of intestinal epithelial cells triggers CCL20-mediated migration of dendritic cells.

artículo científico publicado en 2001

Flagellin-Mediated Protection against Intestinal Yersinia pseudotuberculosis Infection Does Not Require Interleukin-22

artículo científico publicado en 2016

Flagellin-induced NLRC4 phosphorylation primes the inflammasome for activation by NAIP5

artículo científico publicado en 2015

Functional analysis of the carboxy-terminal domain of Bacillus anthracis protective antigen.

artículo científico publicado en 1999

Growth Hormone (GH) Deficient Mice With GHRH Gene Ablation Are Severely Deficient in Vaccine and Immune Responses Against

article

How the gut links innate and adaptive immunity.

artículo científico publicado en 2004

How the gut senses its content.

artículo científico publicado en 2002

IL-17A/F-signaling does not contribute to the initial phase of mucosal inflammation triggered by S. Typhimurium

artículo científico publicado en 2010

IL-22 is produced by γC-independent CD25+ CCR6+ innate murine spleen cells upon inflammatory stimuli and contributes to LPS-induced lethality

artículo científico publicado en 2011

Identification and characterization of a germination operon on the virulence plasmid pXO1 of Bacillus anthracis.

artículo científico publicado en 1999

In vivo germination of Bacillus anthracis spores during murine cutaneous infection.

artículo científico publicado en 2012

Indirect Toll-like receptor 5-mediated activation of conventional dendritic cells promotes the mucosal adjuvant activity of flagellin in the respiratory tract

artículo científico publicado en 2015

Inheritance of the lysozyme inhibitor Ivy was an important evolutionary step by Yersinia pestis to avoid the host innate immune response

artículo científico publicado en 2013

Innate and acquired plasticity of the intestinal immune system

artículo científico publicado en 2005

Interaction of pathogenic bacteria with rabbit appendix M cells: bacterial motility is a key feature in vivo

artículo científico publicado en 2004

Interleukin-22 reduces lung inflammation during influenza A virus infection and protects against secondary bacterial infection.

artículo científico publicado en 2013

Interleukin-7 protects against bacterial respiratory infection by promoting IL-17A-producing innate T-cell response

scientific article published on 18 October 2019

Key role for respiratory CD103(+) dendritic cells, IFN-γ, and IL-17 in protection against Streptococcus pneumoniae infection in response to α-galactosylceramide

artículo científico publicado en 2012

Lactate Inhibits the Pro-Inflammatory Response and Metabolic Reprogramming in Murine Macrophages in a GPR81-Independent Manner

artículo científico publicado en 2016

Lactate and short chain fatty acids produced by microbial fermentation downregulate proinflammatory responses in intestinal epithelial cells and myeloid cells

artículo científico publicado en 2015

Live attenuated Salmonella: a paradigm of mucosal vaccines.

artículo científico publicado en 1999

Local Treatment with Lactate Prevents Intestinal Inflammation in the TNBS-Induced Colitis Model

scientific article published on 27 December 2016

Molecular tools for the study of transcriptional regulation in Bacillus anthracis.

artículo científico publicado en 1995

Mucosal administration of flagellin protects mice from Streptococcus pneumoniae lung infection

artículo científico publicado en 2010

Mucosal interplay among commensal and pathogenic bacteria: lessons from flagellin and Toll-like receptor 5.

artículo científico publicado en 2006

NADPH oxidase deficient mice develop colitis and bacteremia upon infection with normally avirulent, TTSS-1- and TTSS-2-deficient Salmonella Typhimurium

artículo científico publicado en 2013

Nasal immunisation with Salmonella typhimurium producing rotavirus VP2 and VP6 antigens stimulates specific antibody response in serum and milk but fails to protect offspring

artículo científico publicado en 2001

Nasal immunization of mice with virus-like particles protects offspring against rotavirus diarrhea

artículo científico publicado en 2000

Neutrophilic NLRP3 inflammasome-dependent IL-1β secretion regulates the γδT17 cell response in respiratory bacterial infections

artículo científico publicado en 2017

Nod-like receptors: cytosolic watchdogs for immunity against pathogens.

artículo científico publicado en 2007

Pathogen-specific TLR signaling in mucosa: mutual contribution of microbial TLR agonists and virulence factors

artículo científico publicado en 2006

Polarized distribution of inducible nitric oxide synthase regulates activity in intestinal epithelial cells

artículo científico publicado en 2005

Protection against Streptococcus pneumoniae serotype 1 acute infection shows a signature of Th17- and IFN-γ-mediated immunity

artículo científico publicado en 2011

Protective antigen-mediated antibody response against a heterologous protein produced in vivo by Bacillus anthracis

artículo científico publicado en 2000

Pseudomonas aeruginosa LasB Subverts Alveolar Macrophage Activity by Interfering With Bacterial Killing Through Downregulation of Innate Immune Defense, Reactive Oxygen Species Generation, and Complement Activation

scientific article published on 23 July 2018

Radioresistant cells expressing TLR5 control the respiratory epithelium's innate immune responses to flagellin

artículo científico publicado en 2009

Recombinant flagellins with deletions in domains D1, D2, and D3: Characterization as novel immunoadjuvants

scientific article published on 21 December 2018

Role of Toll-like receptors in costimulating cytotoxic T cell responses

artículo científico publicado en 2003

Role of toxin functional domains in anthrax pathogenesis

artículo científico publicado en 2000

Sublingual flagellin protects against acute pneumococcal pneumonia in a TLR5-dependent and NLRC4-independent fashion.

artículo científico publicado en 2016

Superantigenic Yersinia pseudotuberculosis induces the expression of granzymes and perforin by CD4+ T cells

artículo científico publicado en 2015

Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory influenza infection.

artículo científico publicado en 2008

Synthetic gene-regulatory networks in the opportunistic human pathogen Streptococcus pneumoniae

artículo científico publicado en 2020

TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3(neg)CD127+ immune cells in spleen and mucosa

artículo científico publicado en 2010

The GM-CSF Released by Airway Epithelial Cells Orchestrates the Mucosal Adjuvant Activity of Flagellin

scientific article published on 02 October 2020

The adjuvant activity of alphavirus replicons is enhanced by incorporating the microbial molecule flagellin into the replicon

artículo científico publicado en 2013

The atxA gene product activates transcription of the anthrax toxin genes and is essential for virulence

artículo científico publicado en 1995

The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal Salmonella diarrhea

artículo científico publicado en 2010

The scavenger receptors SRA-1 and SREC-I cooperate with TLR2 in the recognition of the hepatitis C virus non-structural protein 3 by dendritic cells.

artículo científico publicado en 2010

The three Bacillus anthracis toxin genes are coordinately regulated by bicarbonate and temperature.

artículo científico publicado en 1994

Therapeutic Synergy Between Antibiotics and Pulmonary Toll-Like Receptor 5 Stimulation in Antibiotic-Sensitive or -Resistant Pneumonia

scientific article published on 09 April 2019

Toll-like receptor 2 is critical for induction of Reg3 beta expression and intestinal clearance of Yersinia pseudotuberculosis

artículo científico publicado en 2009

Toll-like receptor 4 orchestrates neutrophil recruitment into airways during the first hours of Bordetella pertussis infection.

artículo científico publicado en 2013

Toll-like receptor 4 signaling in hematopoietic-lineage cells contributes to the enhanced activity of the human vaccine adjuvant AS01

artículo científico publicado en 2019

Toll-like receptor 5 agonist flagellin reduces influenza A virus replication independently of type I interferon and interleukin 22 and improves antiviral efficacy of oseltamivir

scientific article published on 09 May 2019

Toll-like receptor 5- and lymphotoxin beta receptor-dependent epithelial Ccl20 expression involves the same NF-kappaB binding site but distinct NF-kappaB pathways and dynamics.

artículo científico publicado en 2009

Tollip regulates proinflammatory responses to interleukin-1 and lipopolysaccharide

artículo científico publicado en 2006

Transgenic mouse model harboring the transcriptional fusion ccl20-luciferase as a novel reporter of pro-inflammatory response

artículo científico publicado en 2013

Lista de obras de Jean-Claude Sirard

A Toll-Like Receptor 5 Agonist Improves the Efficacy of Antibiotics in Treatment of Primary and Influenza Virus-Associated Pneumococcal Mouse Infections.

A key role of dendritic cells in probiotic functionality

A rapid, simple and sensitive liquid chromatography tandem mass spectrometry assay to determine amoxicillin concentrations in biological matrix of little volume

Activation of Type 3 innate lymphoid cells and interleukin 22 secretion in the lungs during Streptococcus pneumoniae infection

Adhesin-dependent binding and uptake of Salmonella enterica serovar Typhimurium by dendritic cells.

Airway structural cells regulate TLR5-mediated mucosal adjuvant activity.

Alteration of Flt3-Ligand-dependent de novo generation of conventional dendritic cells during influenza infection contributes to respiratory bacterial superinfection

Antigen delivery by attenuated Bacillus anthracis: new prospects in veterinary vaccines

Attenuated poxviruses expressing a synthetic HIV protein stimulate HLA-A2-restricted cytotoxic T-cell responses

Bacillus anthracis pXO1 virulence plasmid encodes a type 1 DNA topoisomerase

Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa

Boosting the IL-22 response using Flagellin prevents bacterial infection in cigarette smoke-exposed mice

Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection

Characterization of a plasmid region involved in Bacillus anthracis toxin production and pathogenesis

Characterization of structural and immunological properties of a fusion protein between flagellin from Salmonella and lumazine synthase from Brucella.

Characterization of the Bacillus anthracis S-layer: cloning and sequencing of the structural gene

Characterization of the protective immune response to Yersinia pseudotuberculosis infection in mice vaccinated with an LcrV-secreting strain of Lactococcus lactis

Compartmentalized Antimicrobial Defenses in Response to Flagellin.

Delayed expansion and contraction of CD8+ T cell response during infection with virulent Salmonella typhimurium

Deletion of flagellin's hypervariable region abrogates antibody-mediated neutralization and systemic activation of TLR5-dependent immunity.

Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo.

Dendritic cells: the host Achille's heel for mucosal pathogens?

Early Protection against Pertussis Induced by Live Attenuated Bordetella pertussis BPZE1 Depends on TLR4

Entry and survival of Salmonella typhimurium in dendritic cells and presentation of recombinant antigens do not require macrophage-specific virulence factors

Exploration of Bacterial Bottlenecks and Streptococcus pneumoniae Pathogenesis by CRISPRi-Seq

Exposure to Bacterial CpG DNA Protects from Airway Allergic Inflammation by Expanding Regulatory Lung Interstitial Macrophages.

Flagellin promotes myeloid differentiation factor 88-dependent development of Th2-type response

Flagellin stimulation of intestinal epithelial cells triggers CCL20-mediated migration of dendritic cells.

Flagellin-Mediated Protection against Intestinal Yersinia pseudotuberculosis Infection Does Not Require Interleukin-22

Flagellin-induced NLRC4 phosphorylation primes the inflammasome for activation by NAIP5

Functional analysis of the carboxy-terminal domain of Bacillus anthracis protective antigen.

Growth Hormone (GH) Deficient Mice With GHRH Gene Ablation Are Severely Deficient in Vaccine and Immune Responses Against

How the gut links innate and adaptive immunity.

How the gut senses its content.

IL-17A/F-signaling does not contribute to the initial phase of mucosal inflammation triggered by S. Typhimurium

IL-22 is produced by γC-independent CD25+ CCR6+ innate murine spleen cells upon inflammatory stimuli and contributes to LPS-induced lethality

Identification and characterization of a germination operon on the virulence plasmid pXO1 of Bacillus anthracis.

In vivo germination of Bacillus anthracis spores during murine cutaneous infection.

Indirect Toll-like receptor 5-mediated activation of conventional dendritic cells promotes the mucosal adjuvant activity of flagellin in the respiratory tract

Inheritance of the lysozyme inhibitor Ivy was an important evolutionary step by Yersinia pestis to avoid the host innate immune response

Innate and acquired plasticity of the intestinal immune system

Interaction of pathogenic bacteria with rabbit appendix M cells: bacterial motility is a key feature in vivo

Interleukin-22 reduces lung inflammation during influenza A virus infection and protects against secondary bacterial infection.

Interleukin-7 protects against bacterial respiratory infection by promoting IL-17A-producing innate T-cell response

Key role for respiratory CD103(+) dendritic cells, IFN-γ, and IL-17 in protection against Streptococcus pneumoniae infection in response to α-galactosylceramide

Lactate Inhibits the Pro-Inflammatory Response and Metabolic Reprogramming in Murine Macrophages in a GPR81-Independent Manner

Lactate and short chain fatty acids produced by microbial fermentation downregulate proinflammatory responses in intestinal epithelial cells and myeloid cells

Live attenuated Salmonella: a paradigm of mucosal vaccines.

Local Treatment with Lactate Prevents Intestinal Inflammation in the TNBS-Induced Colitis Model

Molecular tools for the study of transcriptional regulation in Bacillus anthracis.

Mucosal administration of flagellin protects mice from Streptococcus pneumoniae lung infection

Mucosal interplay among commensal and pathogenic bacteria: lessons from flagellin and Toll-like receptor 5.

NADPH oxidase deficient mice develop colitis and bacteremia upon infection with normally avirulent, TTSS-1- and TTSS-2-deficient Salmonella Typhimurium

Nasal immunisation with Salmonella typhimurium producing rotavirus VP2 and VP6 antigens stimulates specific antibody response in serum and milk but fails to protect offspring

Nasal immunization of mice with virus-like particles protects offspring against rotavirus diarrhea

Neutrophilic NLRP3 inflammasome-dependent IL-1β secretion regulates the γδT17 cell response in respiratory bacterial infections

Nod-like receptors: cytosolic watchdogs for immunity against pathogens.

Pathogen-specific TLR signaling in mucosa: mutual contribution of microbial TLR agonists and virulence factors

Polarized distribution of inducible nitric oxide synthase regulates activity in intestinal epithelial cells

Protection against Streptococcus pneumoniae serotype 1 acute infection shows a signature of Th17- and IFN-γ-mediated immunity

Protective antigen-mediated antibody response against a heterologous protein produced in vivo by Bacillus anthracis

Pseudomonas aeruginosa LasB Subverts Alveolar Macrophage Activity by Interfering With Bacterial Killing Through Downregulation of Innate Immune Defense, Reactive Oxygen Species Generation, and Complement Activation

Radioresistant cells expressing TLR5 control the respiratory epithelium's innate immune responses to flagellin

Recombinant flagellins with deletions in domains D1, D2, and D3: Characterization as novel immunoadjuvants

Role of Toll-like receptors in costimulating cytotoxic T cell responses

Role of toxin functional domains in anthrax pathogenesis

Sublingual flagellin protects against acute pneumococcal pneumonia in a TLR5-dependent and NLRC4-independent fashion.

Superantigenic Yersinia pseudotuberculosis induces the expression of granzymes and perforin by CD4+ T cells

Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory influenza infection.

Synthetic gene-regulatory networks in the opportunistic human pathogen Streptococcus pneumoniae

TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3(neg)CD127+ immune cells in spleen and mucosa

The GM-CSF Released by Airway Epithelial Cells Orchestrates the Mucosal Adjuvant Activity of Flagellin

The adjuvant activity of alphavirus replicons is enhanced by incorporating the microbial molecule flagellin into the replicon

The atxA gene product activates transcription of the anthrax toxin genes and is essential for virulence

The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal Salmonella diarrhea

The scavenger receptors SRA-1 and SREC-I cooperate with TLR2 in the recognition of the hepatitis C virus non-structural protein 3 by dendritic cells.

The three Bacillus anthracis toxin genes are coordinately regulated by bicarbonate and temperature.

Therapeutic Synergy Between Antibiotics and Pulmonary Toll-Like Receptor 5 Stimulation in Antibiotic-Sensitive or -Resistant Pneumonia

Toll-like receptor 2 is critical for induction of Reg3 beta expression and intestinal clearance of Yersinia pseudotuberculosis