Lista de obras - Hannu Myllykallio - Dominio Público Uruguay

A novel proteomic approach identifies new interaction partners for proliferating cell nuclear antigen

scientific article published on 27 June 2007

Activation of the mismatch-specific endonuclease EndoMS/NucS by the replication clamp is required for high fidelity DNA replication

artículo científico publicado en 2018

Advances and challenges in drug design against tuberculosis: application of in silico approaches

artículo científico publicado en 2018

Bacterial Mode of Replication with Eukaryotic-Like Machinery in a Hyperthermophilic Archaeon

artículo científico publicado en 2000

CRISPR-mediated biocontainment

artículo científico publicado en 2020

Catalytic mechanism and structure of viral flavin-dependent thymidylate synthase ThyX.

artículo científico publicado en 2006

Conservation and Role of Electrostatics in Thymidylate Synthase

artículo científico publicado en 2015

Correction to "Identification of the TyrOH●+ Radical Cation in the Flavoenzyme TrmFO".

artículo científico publicado en 2017

Crystallization and preliminary X-ray analysis of a RecB-family nuclease from the archaeon Pyrococcus abyssi

artículo científico publicado en 2007

Cytochrome c(y) of Rhodobacter capsulatus is attached to the cytoplasmic membrane by an uncleaved signal sequence-like anchor.

artículo científico publicado en 1997

DNA replication restart and cellular dynamics of Hef helicase/nuclease protein in Haloferax volcanii.

artículo científico

Design, synthesis and evaluation of potent thymidylate synthase X inhibitors.

artículo científico publicado en 2008

Differential interaction kinetics of a bipolar structure-specific endonuclease with DNA flaps revealed by single-molecule imaging

artículo científico publicado en 2014

Discovery of a new Mycobacterium tuberculosis thymidylate synthase X inhibitor with a unique inhibition profile

artículo científico publicado en 2017

Diversity of circular RNAs and RNA ligases in archaeal cells

scientific article published on 15 June 2019

Dual role for cytochrome cbb3 oxidase in clinically relevant proteobacteria?

artículo científico publicado en 2000

Electron-transfer supercomplexes in photosynthesis and respiration

artículo científico publicado en 2000

Enabling large-scale genome editing at repetitive elements by reducing DNA nicking

artículo científico publicado en 2020

Expression and purification of untagged and histidine-tagged folate-dependent tRNA:m5U54 methyltransferase from Bacillus subtilis.

artículo científico publicado en 2010

Function and evolution of plasmid-borne genes for pyrimidine biosynthesis in Borrelia spp.

artículo científico publicado en 2006

Functional analysis of the Mycobacterium tuberculosis FAD-dependent thymidylate synthase, ThyX, reveals new amino acid residues contributing to an extended ThyX motif.

artículo científico publicado en 2008

G-Quadruplexes in the Archaea Domain

scientific article published on 21 September 2020

Genetic and physical mapping of DNA replication origins in Haloferax volcanii

artículo científico publicado en 2007

High-throughput sequencing reveals circular substrates for an archaeal RNA ligase

artículo científico publicado en 2017

Hotspots in an obligate homodimeric anticancer target. Structural and functional effects of interfacial mutations in human thymidylate synthase.

artículo científico publicado en 2015

Identification of putative chromosomal origins of replication in Archaea

scientific article published on 01 May 1999

Identification of the TyrOH•+ Radical Cation in the Flavoenzyme TrmFO.

artículo científico publicado en 2017

Identification, purification, and characterization of an eukaryotic-like phosphopantetheine adenylyltransferase (coenzyme A biosynthetic pathway) in the hyperthermophilic archaeon Pyrococcus abyssi.

artículo científico publicado en 2003

In vitro detection of the enzymatic activity of folate-dependent tRNA (Uracil-54,-C5)-methyltransferase: evolutionary implications.

artículo científico publicado en 2007

Intracellular dynamics of archaeal FANCM homologue Hef in response to halted DNA replication

artículo científico publicado en 2013

Isolation and identification of two extremely halophilic archaea from sebkhas in the Algerian Sahara

artículo científico publicado en 2018

Life without dihydrofolate reductase FolA.

artículo científico publicado en 2003

Mapping of a chromosome replication origin in an archaeon: response

artículo científico publicado en 2000

Membrane-anchored cytochrome cy mediated microsecond time range electron transfer from the cytochrome bc1 complex to the reaction center in Rhodobacter capsulatus

scientific article published on 01 April 1998

Mobile cytochrome c2 and membrane-anchored cytochrome cy are both efficient electron donors to the cbb3- and aa3-type cytochrome c oxidases during respiratory growth of Rhodobacter sphaeroides.

artículo científico publicado en 2001

Novel approaches for targeting thymidylate synthase to overcome the resistance and toxicity of anticancer drugs.

artículo científico publicado en 2010

Predictive modeling targets thymidylate synthase ThyX in Mycobacterium tuberculosis

artículo científico publicado en 2016

Rhodobacter capsulatus contains a novel cb-type cytochrome c oxidase without a CuA center

scientific article published on 01 March 1994

Snapshots of archaeal DNA replication and repair in living cells using super-resolution imaging

artículo científico publicado en 2018

Structural and functional insight into serine hydroxymethyltransferase from Helicobacter pylori

artículo científico publicado en 2018

Structure and function of a novel endonuclease acting on branched DNA substrates

artículo científico publicado en 2011

Substrate interaction dynamics and oxygen control in the active site of thymidylate synthase ThyX.

artículo científico publicado en 2014

Synthesis and Structure-Activity Relationship Studies of Benzo[b][1,4]oxazin-3(4H)-one Analogues as Inhibitors of Mycobacterial Thymidylate Synthase X

scientific article published on 20 February 2019

Targeting of Helicobacter pylori thymidylate synthase ThyX by non-mitotoxic hydroxy-naphthoquinones

artículo científico publicado en 2015

The RegB/RegA two-component regulatory system controls synthesis of photosynthesis and respiratory electron transfer components in Rhodobacter capsulatus.

artículo científico publicado en 2001

The heterodimeric primase from the euryarchaeon Pyrococcus abyssi: a multifunctional enzyme for initiation and repair?

scientific article published on 12 October 2007

The membrane-extrinsic domain of cytochrome b(558/566) from the archaeon Sulfolobus acidocaldarius performs pivoting movements with respect to the membrane surface.

artículo científico publicado en 2001

Transcriptional activation and cell cycle block are the keys for 5-fluorouracil induced up-regulation of human thymidylate synthase expression

artículo científico publicado en 2012

Ultrafast real-time visualization of active site flexibility of flavoenzyme thymidylate synthase ThyX

artículo científico publicado en 2013

Unique Features and Anti-microbial Targeting of Folate- and Flavin-Dependent Methyltransferases Required for Accurate Maintenance of Genetic Information.

artículo científico publicado en 2018

Lista de obras de Hannu Myllykallio

A novel proteomic approach identifies new interaction partners for proliferating cell nuclear antigen

Activation of the mismatch-specific endonuclease EndoMS/NucS by the replication clamp is required for high fidelity DNA replication

Advances and challenges in drug design against tuberculosis: application of in silico approaches

Bacterial Mode of Replication with Eukaryotic-Like Machinery in a Hyperthermophilic Archaeon

CRISPR-mediated biocontainment

Catalytic mechanism and structure of viral flavin-dependent thymidylate synthase ThyX.

Conservation and Role of Electrostatics in Thymidylate Synthase

Correction to "Identification of the TyrOH●+ Radical Cation in the Flavoenzyme TrmFO".

Crystallization and preliminary X-ray analysis of a RecB-family nuclease from the archaeon Pyrococcus abyssi

Cytochrome c(y) of Rhodobacter capsulatus is attached to the cytoplasmic membrane by an uncleaved signal sequence-like anchor.

DNA replication restart and cellular dynamics of Hef helicase/nuclease protein in Haloferax volcanii.

Design, synthesis and evaluation of potent thymidylate synthase X inhibitors.

Differential interaction kinetics of a bipolar structure-specific endonuclease with DNA flaps revealed by single-molecule imaging

Discovery of a new Mycobacterium tuberculosis thymidylate synthase X inhibitor with a unique inhibition profile

Diversity of circular RNAs and RNA ligases in archaeal cells

Dual role for cytochrome cbb3 oxidase in clinically relevant proteobacteria?

Electron-transfer supercomplexes in photosynthesis and respiration

Enabling large-scale genome editing at repetitive elements by reducing DNA nicking

Expression and purification of untagged and histidine-tagged folate-dependent tRNA:m5U54 methyltransferase from Bacillus subtilis.

Function and evolution of plasmid-borne genes for pyrimidine biosynthesis in Borrelia spp.

Functional analysis of the Mycobacterium tuberculosis FAD-dependent thymidylate synthase, ThyX, reveals new amino acid residues contributing to an extended ThyX motif.

G-Quadruplexes in the Archaea Domain

Genetic and physical mapping of DNA replication origins in Haloferax volcanii

High-throughput sequencing reveals circular substrates for an archaeal RNA ligase

Hotspots in an obligate homodimeric anticancer target. Structural and functional effects of interfacial mutations in human thymidylate synthase.

Identification of putative chromosomal origins of replication in Archaea

Identification of the TyrOH•+ Radical Cation in the Flavoenzyme TrmFO.

Identification, purification, and characterization of an eukaryotic-like phosphopantetheine adenylyltransferase (coenzyme A biosynthetic pathway) in the hyperthermophilic archaeon Pyrococcus abyssi.

In vitro detection of the enzymatic activity of folate-dependent tRNA (Uracil-54,-C5)-methyltransferase: evolutionary implications.

Intracellular dynamics of archaeal FANCM homologue Hef in response to halted DNA replication

Isolation and identification of two extremely halophilic archaea from sebkhas in the Algerian Sahara

Life without dihydrofolate reductase FolA.

Mapping of a chromosome replication origin in an archaeon: response

Membrane-anchored cytochrome cy mediated microsecond time range electron transfer from the cytochrome bc1 complex to the reaction center in Rhodobacter capsulatus

Mobile cytochrome c2 and membrane-anchored cytochrome cy are both efficient electron donors to the cbb3- and aa3-type cytochrome c oxidases during respiratory growth of Rhodobacter sphaeroides.

Novel approaches for targeting thymidylate synthase to overcome the resistance and toxicity of anticancer drugs.

Predictive modeling targets thymidylate synthase ThyX in Mycobacterium tuberculosis

Rhodobacter capsulatus contains a novel cb-type cytochrome c oxidase without a CuA center

Snapshots of archaeal DNA replication and repair in living cells using super-resolution imaging

Structural and functional insight into serine hydroxymethyltransferase from Helicobacter pylori

Structure and function of a novel endonuclease acting on branched DNA substrates

Substrate interaction dynamics and oxygen control in the active site of thymidylate synthase ThyX.

Synthesis and Structure-Activity Relationship Studies of Benzo[b][1,4]oxazin-3(4H)-one Analogues as Inhibitors of Mycobacterial Thymidylate Synthase X

Targeting of Helicobacter pylori thymidylate synthase ThyX by non-mitotoxic hydroxy-naphthoquinones

The RegB/RegA two-component regulatory system controls synthesis of photosynthesis and respiratory electron transfer components in Rhodobacter capsulatus.

The heterodimeric primase from the euryarchaeon Pyrococcus abyssi: a multifunctional enzyme for initiation and repair?

The membrane-extrinsic domain of cytochrome b(558/566) from the archaeon Sulfolobus acidocaldarius performs pivoting movements with respect to the membrane surface.

Transcriptional activation and cell cycle block are the keys for 5-fluorouracil induced up-regulation of human thymidylate synthase expression

Ultrafast real-time visualization of active site flexibility of flavoenzyme thymidylate synthase ThyX

Unique Features and Anti-microbial Targeting of Folate- and Flavin-Dependent Methyltransferases Required for Accurate Maintenance of Genetic Information.