Lista de obras - David W Fardo - Dominio Público Uruguay

"New Old Pathologies": AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS).

artículo científico publicado en 2016

A 2-step penalized regression method for family-based next-generation sequencing association studies

artículo científico publicado en 2014

A Customized Quantitative PCR MicroRNA Panel Provides a Technically Robust Context for Studying Neurodegenerative Disease Biomarkers and Indicates a High Correlation Between Cerebrospinal Fluid and Choroid Plexus MicroRNA Expression.

artículo científico publicado en 2016

A Summary Score for the Framingham Heart Study Neuropsychological Battery.

artículo científico publicado en 2015

ABCA7 expression is associated with Alzheimer's disease polymorphism and disease status

artículo científico publicado en 2013

ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology

artículo científico publicado en 2014

ABCC9/SUR2 in the brain: Implications for hippocampal sclerosis of aging and a potential therapeutic target

artículo científico publicado en 2015

APOE-ε2 and APOE-ε4 correlate with increased amyloid accumulation in cerebral vasculature

artículo científico publicado en 2013

Adjusting for mortality when identifying risk factors for transitions to mild cognitive impairment and dementia

artículo científico publicado en 2013

Alzheimer Disease Pathology-Associated Polymorphism in a Complex Variable Number of Tandem Repeat Region Within the MUC6 Gene, Near the AP2A2 Gene

artículo científico publicado en 2020

An intronic PICALM polymorphism, rs588076, is associated with allelic expression of a PICALM isoform

artículo científico publicado en 2014

Analysis of genes (TMEM106B, GRN, ABCC9, KCNMB2, and APOE) implicated in risk for LATE-NC and hippocampal sclerosis provides pathogenetic insights: a retrospective genetic association study

artículo científico publicado en 2021

Assessing the discriminant ability, reliability, and comparability of multiple short forms of the Boston Naming Test in an Alzheimer's disease center cohort

artículo científico publicado en 2015

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Automated quality control for genome wide association studies

artículo científico publicado en 2016

Brain arteriolosclerosis

artículo científico publicado en 2020

CD33 Alzheimer's risk-altering polymorphism, CD33 expression, and exon 2 splicing.

artículo científico publicado en 2013

CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN/PGRN.

artículo científico publicado en 2017

Cancer history associates with a lower burden of dementia and Alzheimer’s‐type neuropathology in autopsied research volunteers

scientific article published in 2021

Correction: Genetic data and cognitively defined late-onset Alzheimer's disease subgroups

scientific article published on 15 January 2019

Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease

artículo científico publicado en 2016

Detergent Insoluble Proteins and Inclusion Body-Like Structures Immunoreactive for PRKDC/DNA-PK/DNA-PKcs, FTL, NNT, and AIFM1 in the Amygdala of Cognitively Impaired Elderly Persons.

artículo científico publicado en 2017

Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology

artículo científico publicado en 2016

Dichotomous scoring of TDP-43 proteinopathy from specific brain regions in 27 academic research centers: associations with Alzheimer's disease and cerebrovascular disease pathologies

scholarly article by Yuriko Katsumata et al published 19 December 2018 in Acta neuropathologica communications

Distinct clinicopathologic clusters of persons with TDP-43 proteinopathy

artículo científico publicado en 2020

Effects of alcohol consumption on cognition and regional brain volumes among older adults

artículo científico publicado en 2014

Estimation of Multi-state Models with Missing Covariate Values Based on Observed Data Likelihood

artículo científico publicado en 2018

Evaluation of CD33 as a genetic risk factor for Alzheimer's disease

artículo científico publicado en 2019

Functional human GRIN2B promoter polymorphism and variation of mental processing speed in older adults. ⬇️

artículo científico publicado en 2017

GAW20: methods and strategies for the new frontiers of epigenetics and pharmacogenomics

Gene-based association study of genes linked to hippocampal sclerosis of aging neuropathology: GRN, TMEM106B, ABCC9, and KCNMB2.

artículo científico publicado en 2017

Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees

artículo científico publicado en 2014

Genetic Comparison of Symptomatic and Asymptomatic Persons With Alzheimer Disease Neuropathology

artículo científico publicado en 2016

Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.

artículo científico publicado en 2018

Genetic data and cognitively-defined late-onset Alzheimer's disease subgroups

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

artículo científico publicado en 2019

Genetic variants and functional pathways associated with resilience to Alzheimer's disease

scientific article published on 01 August 2020

Genetics ignite focus on microglial inflammation in Alzheimer's disease

artículo científico publicado en 2015

Genetics of CD33 in Alzheimer's disease and acute myeloid leukemia.

artículo científico publicado en 2015

Genetics of PICALM expression and Alzheimer's disease.

artículo científico publicado en 2014

Genetics of clusterin isoform expression and Alzheimer's disease risk

artículo científico publicado en 2012

Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging

artículo científico publicado en 2016

Hierarchical Clustering Analyses of Plasma Proteins in Subjects With Cardiovascular Risk Factors Identify Informative Subsets Based on Differential Levels of Angiogenic and Inflammatory Biomarkers

artículo científico publicado en 2020

Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease

artículo científico publicado en 2013

Impact of Population Stratification on Family-Based Association in an Admixed Population

artículo científico publicado en 2015

Impact of home visit capacity on genetic association studies of late-onset Alzheimer's disease.

artículo científico publicado en 2017

Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples

artículo científico publicado en 2013

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report.

artículo científico publicado en 2019

Longitudinal trajectories of cholesterol from midlife through late life according to apolipoprotein E allele status

artículo científico publicado en 2014

Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential

artículo científico publicado en 2014

Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease

article

Mild cognitive impairment: statistical models of transition using longitudinal clinical data

artículo científico publicado en 2012

Modeling of multivariate longitudinal phenotypes in family genetic studies with Bayesian multiplicity adjustment

artículo científico publicado en 2014

Multi-state models and missing covariate data: Expectation-Maximization algorithm for likelihood estimation

artículo científico publicado en 2017

New insights into the genetic etiology of Alzheimer's disease and related dementias

artículo científico publicado en 2022

Novel human ABCC9/SUR2 brain-expressed transcripts and an eQTL relevant to hippocampal sclerosis of aging

artículo científico publicado en 2015

On combining family- and population-based sequencing data

artículo científico publicado en 2016

On family-based genome-wide association studies with large pedigrees: observations and recommendations.

artículo científico publicado en 2014

On quality control measures in genome-wide association studies: a test to assess the genotyping quality of individual probands in family-based association studies and an application to the HapMap data

artículo científico publicado en 2009

Outcomes after diagnosis of mild cognitive impairment in a large autopsy series

artículo científico publicado en 2017

Overlapping but distinct TDP-43 and tau pathologic patterns in aged hippocampi

artículo científico publicado en 2017

Patterns and predictors of chronic opioid use in older adults: A retrospective cohort study

artículo científico publicado en 2019

Peripheral Inflammation, Apolipoprotein E4, and Amyloid-β Interact to Induce Cognitive and Cerebrovascular Dysfunction

artículo científico publicado en 2017

Prevalence and Clinical Phenotype of Quadruple Misfolded Proteins in Older Adults

scientific article published on 22 June 2020

Principals about principal components in statistical genetics

artículo científico publicado en 2019

Quantitative phenotype scan statistic (QPSS) reveals rare variant associations with Alzheimer's disease endophenotypes

artículo científico publicado en 2020

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

artículo científico publicado en 2017

Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology

artículo científico publicado en 2015

Recovering unused information in genome-wide association studies: the benefit of analyzing SNPs out of Hardy-Weinberg equilibrium

artículo científico publicado en 2009

Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2

artículo científico publicado en 2022

Reply: LATE to the PART-y

artículo científico publicado en 2019

Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals

artículo científico publicado en 2016

Risk of incident clinical diagnosis of Alzheimer's disease-type dementia attributable to pathology-confirmed vascular disease

artículo científico publicado en 2016

Self-Reported Memory Complaints: A Comparison of Demented and Unimpaired Outcomes

artículo científico publicado en 2016

Self-reported head injury and risk of late-life impairment and AD pathology in an AD center cohort

artículo científico publicado en 2014

Self-reported memory complaints: implications from a longitudinal cohort with autopsies

artículo científico publicado en 2014

Systems biology approach to late-onset Alzheimer's disease genome-wide association study identifies novel candidate genes validated using brain expression data and Caenorhabditis elegans experiments

artículo científico publicado en 2017

TDP-43 proteinopathy in aging: Associations with risk-associated gene variants and with brain parenchymal thyroid hormone levels

scientific article published on 23 January 2019

The Amygdala as a Locus of Pathologic Misfolding in Neurodegenerative Diseases

artículo científico publicado en 2017

The Effect of Vascular Neuropathology on Late-life Cognition: Results from the SMART Project

artículo científico publicado en 2016

The MUC6/AP2A2 Locus and Its Relevance to Alzheimer's Disease: A Review

artículo científico publicado en 2020

The Statistical Modeling of Aging and Risk of Transition Project: Data Collection and Harmonization Across 11 Longitudinal Cohort Studies of Aging, Cognition, and Dementia

The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable

artículo científico publicado en 2016

The relationship between midlife and late life alcohol consumption, APOE e4 and the decline in learning and memory among older adults

artículo científico publicado en 2013

Tobacco Smoking and Dementia in a Kentucky Cohort: A Competing Risk Analysis

artículo científico publicado en 2019

Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs

artículo científico publicado en 2018

Using Mendelian inheritance errors as quality control criteria in whole genome sequencing data set.

artículo científico publicado en 2014

Visual Arts Education improves self-esteem for persons with dementia and reduces caregiver burden: A randomized controlled trial.

artículo científico publicado en 2018

Lista de obras de David W Fardo

"New Old Pathologies": AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS).

A 2-step penalized regression method for family-based next-generation sequencing association studies

A Customized Quantitative PCR MicroRNA Panel Provides a Technically Robust Context for Studying Neurodegenerative Disease Biomarkers and Indicates a High Correlation Between Cerebrospinal Fluid and Choroid Plexus MicroRNA Expression.

A Summary Score for the Framingham Heart Study Neuropsychological Battery.

ABCA7 expression is associated with Alzheimer's disease polymorphism and disease status

ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology

ABCC9/SUR2 in the brain: Implications for hippocampal sclerosis of aging and a potential therapeutic target

APOE-ε2 and APOE-ε4 correlate with increased amyloid accumulation in cerebral vasculature

Adjusting for mortality when identifying risk factors for transitions to mild cognitive impairment and dementia

Alzheimer Disease Pathology-Associated Polymorphism in a Complex Variable Number of Tandem Repeat Region Within the MUC6 Gene, Near the AP2A2 Gene

An intronic PICALM polymorphism, rs588076, is associated with allelic expression of a PICALM isoform

Analysis of genes (TMEM106B, GRN, ABCC9, KCNMB2, and APOE) implicated in risk for LATE-NC and hippocampal sclerosis provides pathogenetic insights: a retrospective genetic association study

Assessing the discriminant ability, reliability, and comparability of multiple short forms of the Boston Naming Test in an Alzheimer's disease center cohort

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Automated quality control for genome wide association studies

Brain arteriolosclerosis

CD33 Alzheimer's risk-altering polymorphism, CD33 expression, and exon 2 splicing.

CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN/PGRN.

Cancer history associates with a lower burden of dementia and Alzheimer’s‐type neuropathology in autopsied research volunteers

Correction: Genetic data and cognitively defined late-onset Alzheimer's disease subgroups

Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease

Detergent Insoluble Proteins and Inclusion Body-Like Structures Immunoreactive for PRKDC/DNA-PK/DNA-PKcs, FTL, NNT, and AIFM1 in the Amygdala of Cognitively Impaired Elderly Persons.

Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology

Dichotomous scoring of TDP-43 proteinopathy from specific brain regions in 27 academic research centers: associations with Alzheimer's disease and cerebrovascular disease pathologies

Distinct clinicopathologic clusters of persons with TDP-43 proteinopathy

Effects of alcohol consumption on cognition and regional brain volumes among older adults

Estimation of Multi-state Models with Missing Covariate Values Based on Observed Data Likelihood

Evaluation of CD33 as a genetic risk factor for Alzheimer's disease

Functional human GRIN2B promoter polymorphism and variation of mental processing speed in older adults. ⬇️

GAW20: methods and strategies for the new frontiers of epigenetics and pharmacogenomics

Gene-based association study of genes linked to hippocampal sclerosis of aging neuropathology: GRN, TMEM106B, ABCC9, and KCNMB2.

Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees

Genetic Comparison of Symptomatic and Asymptomatic Persons With Alzheimer Disease Neuropathology

Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.

Genetic data and cognitively-defined late-onset Alzheimer's disease subgroups

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Genetic variants and functional pathways associated with resilience to Alzheimer's disease

Genetics ignite focus on microglial inflammation in Alzheimer's disease

Genetics of CD33 in Alzheimer's disease and acute myeloid leukemia.

Genetics of PICALM expression and Alzheimer's disease.

Genetics of clusterin isoform expression and Alzheimer's disease risk

Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging

Hierarchical Clustering Analyses of Plasma Proteins in Subjects With Cardiovascular Risk Factors Identify Informative Subsets Based on Differential Levels of Angiogenic and Inflammatory Biomarkers

Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease

Impact of Population Stratification on Family-Based Association in an Admixed Population

Impact of home visit capacity on genetic association studies of late-onset Alzheimer's disease.

Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report.

Longitudinal trajectories of cholesterol from midlife through late life according to apolipoprotein E allele status

Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential

Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease

Mild cognitive impairment: statistical models of transition using longitudinal clinical data

Modeling of multivariate longitudinal phenotypes in family genetic studies with Bayesian multiplicity adjustment

Multi-state models and missing covariate data: Expectation-Maximization algorithm for likelihood estimation

New insights into the genetic etiology of Alzheimer's disease and related dementias

Novel human ABCC9/SUR2 brain-expressed transcripts and an eQTL relevant to hippocampal sclerosis of aging

On combining family- and population-based sequencing data

On family-based genome-wide association studies with large pedigrees: observations and recommendations.

On quality control measures in genome-wide association studies: a test to assess the genotyping quality of individual probands in family-based association studies and an application to the HapMap data

Outcomes after diagnosis of mild cognitive impairment in a large autopsy series

Overlapping but distinct TDP-43 and tau pathologic patterns in aged hippocampi

Patterns and predictors of chronic opioid use in older adults: A retrospective cohort study

Peripheral Inflammation, Apolipoprotein E4, and Amyloid-β Interact to Induce Cognitive and Cerebrovascular Dysfunction

Prevalence and Clinical Phenotype of Quadruple Misfolded Proteins in Older Adults

Principals about principal components in statistical genetics

Quantitative phenotype scan statistic (QPSS) reveals rare variant associations with Alzheimer's disease endophenotypes

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology

Recovering unused information in genome-wide association studies: the benefit of analyzing SNPs out of Hardy-Weinberg equilibrium

Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2

Reply: LATE to the PART-y

Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals

Risk of incident clinical diagnosis of Alzheimer's disease-type dementia attributable to pathology-confirmed vascular disease

Self-Reported Memory Complaints: A Comparison of Demented and Unimpaired Outcomes

Self-reported head injury and risk of late-life impairment and AD pathology in an AD center cohort

Self-reported memory complaints: implications from a longitudinal cohort with autopsies

Systems biology approach to late-onset Alzheimer's disease genome-wide association study identifies novel candidate genes validated using brain expression data and Caenorhabditis elegans experiments

TDP-43 proteinopathy in aging: Associations with risk-associated gene variants and with brain parenchymal thyroid hormone levels

The Amygdala as a Locus of Pathologic Misfolding in Neurodegenerative Diseases