Lista de obras - Craig A Harrison - Dominio Público Uruguay

2-Phenyl and 2-heterocyclic-4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridines as inhibitors of TGF-β1 and activin A signalling.

artículo científico publicado en 2010

A Novel, More Efficient Approach to Generate Bioactive Inhibins

artículo científico publicado en 2016

A common biosynthetic pathway governs the dimerization and secretion of inhibin and related transforming growth factor beta (TGFbeta) ligands

artículo científico publicado en 2009

Aberrant GDF9 expression and activation are associated with common human ovarian disorders.

artículo científico publicado en 2014

Activation of latent human GDF9 by a single residue change (Gly 391 Arg) in the mature domain

artículo científico publicado en 2012

Activin-A binds follistatin and type II receptors through overlapping binding sites: generation of mutants with isolated binding activities

artículo científico publicado en 2006

Activins and inhibins and their signaling.

artículo científico publicado en 2004

BMP15 Mutations Associated With Primary Ovarian Insufficiency Reduce Expression, Activity, or Synergy With GDF9.

artículo científico publicado en 2017

Biological activity and in vivo half-life of pro-activin A in male rats.

artículo científico publicado en 2015

Characterization of a mutant recombinant S100 protein using electrospray ionization mass spectrometry

scientific article published on 01 January 1997

Cumulin, an Oocyte-secreted Heterodimer of the Transforming Growth Factor-β Family, Is a Potent Activator of Granulosa Cells and Improves Oocyte Quality

artículo científico publicado en 2015

Development of novel activin-targeted therapeutics

artículo científico publicado en 2014

Differential Effects of IL6 and Activin A in the Development of Cancer-Associated Cachexia.

artículo científico publicado en 2016

Elevated expression of activins promotes muscle wasting and cachexia.

artículo científico publicado en 2013

Expression of nodal signalling components in cycling human endometrium and in endometrial cancer

artículo científico publicado en 2009

Extra-ovarian expression and activity of growth differentiation factor 9.

artículo científico publicado en 2009

Feedback regulation by inhibins A and B of the pituitary secretion of follicle-stimulating hormone

scientific article published on January 2011

Functional analysis of the human inhibin alpha subunit variant A257T and its potential role in premature ovarian failure.

artículo científico publicado en 2007

Generation of a specific activin antagonist by modification of the activin A propeptide.

artículo científico publicado en 2011

Germline mutations of inhibins in early-onset ovarian epithelial tumors

artículo científico publicado en 2013

Growth differentiation factor 9:bone morphogenetic protein 15 (GDF9:BMP15) synergism and protein heterodimerization.

artículo científico publicado en 2013

Hormonal regulation of sertoli cell micro-RNAs at spermiation

artículo científico publicado en 2011

HtrA3 Is Downregulated in Cancer Cell Lines and Significantly Reduced in Primary Serous and Granulosa Cell Ovarian Tumors.

artículo científico publicado en 2013

Identification of distinct inhibin and transforming growth factor beta-binding sites on betaglycan: functional separation of betaglycan co-receptor actions.

artículo científico publicado en 2006

Identification of protein binding partners of ALK-5 kinase inhibitors

artículo científico publicado en 2013

Immunodetection of the murine chemotactic protein CP-10 in bleomycin-induced pulmonary injury.

artículo científico publicado en 1998

Induction of the S100 chemotactic protein, CP-10, in murine microvascular endothelial cells by proinflammatory stimuli

scientific article published on 01 December 1997

Inhibin B is a more potent suppressor of rat follicle-stimulating hormone release than inhibin a in vitro and in vivo.

artículo científico publicado en 2009

Inhibin Biosynthesis and Activity Are Limited by a Prodomain-Derived Peptide

artículo científico publicado en 2015

Inhibin binding sites and proteins in pituitary, gonadal, adrenal and bone cells.

artículo científico publicado en 2001

Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy

artículo científico publicado en 2018

Interleukin 11 and activin A synergise to regulate progesterone-induced but not cAMP-induced decidualization.

artículo científico publicado en 2010

Lentiviral transduction of rat Sertoli cells as a means to modify gene expression.

artículo científico publicado en 2012

Loss of betaglycan contributes to the malignant properties of human granulosa tumor cells.

artículo científico publicado en 2009

Molecular characterization of latent GDF8 reveals mechanisms of activation.

artículo científico publicado en 2018

Multiple Soluble TGF-β Receptors in Addition to Soluble Endoglin Are Elevated in Preeclamptic Serum and They Synergistically Inhibit TGF-β Signaling

artículo científico publicado en 2017

Mutational analysis of betaglycan/TGF-betaRIII in premature ovarian failure

artículo científico publicado en 2006

New insights into the mechanisms of activin action and inhibition ⬇️

artículo científico publicado el 8 de julio de 2011

Oxidation regulates the inflammatory properties of the murine S100 protein S100A8

artículo científico publicado en 1999

Prodomains regulate the synthesis, extracellular localisation and activity of TGF-β superfamily ligands

artículo científico publicado en 2011

Retinoic acid promotes Sertoli cell differentiation and antagonises activin-induced proliferation.

artículo científico publicado en 2013

Selection of internal control genes for analysis of gene expression in normal and diseased human dermal fibroblasts using quantitative real-time PCR.

artículo científico publicado en 2016

Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice.

artículo científico publicado en 2016

Species differences in the expression and activity of bone morphogenetic protein 15.

artículo científico publicado en 2013

Specific targeting of TGF-β family ligands demonstrates distinct roles in the regulation of muscle mass in health and disease

artículo científico publicado en 2017

Structural basis for potency differences between GDF8 and GDF11.

artículo científico publicado en 2017

The Synthesis and Secretion of Inhibins

artículo científico publicado el 1 de enero de 2011

The TGF-β Signalling Network in Muscle Development, Adaptation and Disease.

artículo científico publicado en 2016

The activin A antagonist follistatin inhibits asthmatic airway remodelling

artículo científico publicado en 2012

The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma.

scientific article published on 20 February 2017

The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass.

artículo científico publicado en 2013

Two distinct regions of latency-associated peptide coordinate stability of the latent transforming growth factor-beta1 complex

artículo científico publicado en 2010

Use of detergent-based buffers allows detection of precursor inhibin forms in an immunoassay format.

artículo científico publicado en 2013

Lista de obras de Craig A Harrison

2-Phenyl and 2-heterocyclic-4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridines as inhibitors of TGF-β1 and activin A signalling.

A Novel, More Efficient Approach to Generate Bioactive Inhibins

A common biosynthetic pathway governs the dimerization and secretion of inhibin and related transforming growth factor beta (TGFbeta) ligands

Aberrant GDF9 expression and activation are associated with common human ovarian disorders.

Activation of latent human GDF9 by a single residue change (Gly 391 Arg) in the mature domain

Activin-A binds follistatin and type II receptors through overlapping binding sites: generation of mutants with isolated binding activities

Activins and inhibins and their signaling.

BMP15 Mutations Associated With Primary Ovarian Insufficiency Reduce Expression, Activity, or Synergy With GDF9.

Biological activity and in vivo half-life of pro-activin A in male rats.

Characterization of a mutant recombinant S100 protein using electrospray ionization mass spectrometry

Cumulin, an Oocyte-secreted Heterodimer of the Transforming Growth Factor-β Family, Is a Potent Activator of Granulosa Cells and Improves Oocyte Quality

Development of novel activin-targeted therapeutics

Differential Effects of IL6 and Activin A in the Development of Cancer-Associated Cachexia.

Elevated expression of activins promotes muscle wasting and cachexia.

Expression of nodal signalling components in cycling human endometrium and in endometrial cancer

Extra-ovarian expression and activity of growth differentiation factor 9.

Feedback regulation by inhibins A and B of the pituitary secretion of follicle-stimulating hormone

Functional analysis of the human inhibin alpha subunit variant A257T and its potential role in premature ovarian failure.

Generation of a specific activin antagonist by modification of the activin A propeptide.

Germline mutations of inhibins in early-onset ovarian epithelial tumors

Growth differentiation factor 9:bone morphogenetic protein 15 (GDF9:BMP15) synergism and protein heterodimerization.

Hormonal regulation of sertoli cell micro-RNAs at spermiation

HtrA3 Is Downregulated in Cancer Cell Lines and Significantly Reduced in Primary Serous and Granulosa Cell Ovarian Tumors.

Identification of distinct inhibin and transforming growth factor beta-binding sites on betaglycan: functional separation of betaglycan co-receptor actions.

Identification of protein binding partners of ALK-5 kinase inhibitors

Immunodetection of the murine chemotactic protein CP-10 in bleomycin-induced pulmonary injury.

Induction of the S100 chemotactic protein, CP-10, in murine microvascular endothelial cells by proinflammatory stimuli

Inhibin B is a more potent suppressor of rat follicle-stimulating hormone release than inhibin a in vitro and in vivo.

Inhibin Biosynthesis and Activity Are Limited by a Prodomain-Derived Peptide

Inhibin binding sites and proteins in pituitary, gonadal, adrenal and bone cells.

Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy

Interleukin 11 and activin A synergise to regulate progesterone-induced but not cAMP-induced decidualization.

Lentiviral transduction of rat Sertoli cells as a means to modify gene expression.

Loss of betaglycan contributes to the malignant properties of human granulosa tumor cells.

Molecular characterization of latent GDF8 reveals mechanisms of activation.

Multiple Soluble TGF-β Receptors in Addition to Soluble Endoglin Are Elevated in Preeclamptic Serum and They Synergistically Inhibit TGF-β Signaling

Mutational analysis of betaglycan/TGF-betaRIII in premature ovarian failure

New insights into the mechanisms of activin action and inhibition ⬇️

Oxidation regulates the inflammatory properties of the murine S100 protein S100A8

Prodomains regulate the synthesis, extracellular localisation and activity of TGF-β superfamily ligands

Retinoic acid promotes Sertoli cell differentiation and antagonises activin-induced proliferation.

Selection of internal control genes for analysis of gene expression in normal and diseased human dermal fibroblasts using quantitative real-time PCR.

Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice.

Species differences in the expression and activity of bone morphogenetic protein 15.

Specific targeting of TGF-β family ligands demonstrates distinct roles in the regulation of muscle mass in health and disease

Structural basis for potency differences between GDF8 and GDF11.

The Synthesis and Secretion of Inhibins

The TGF-β Signalling Network in Muscle Development, Adaptation and Disease.

The activin A antagonist follistatin inhibits asthmatic airway remodelling

The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma.

The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass.

Two distinct regions of latency-associated peptide coordinate stability of the latent transforming growth factor-beta1 complex

Use of detergent-based buffers allows detection of precursor inhibin forms in an immunoassay format.