Lista de obras - Jianjun Cheng - Dominio Público Uruguay

5-HT2C Agonists Modulate Schizophrenia-Like Behaviors in Mice.

artículo científico publicado en 2017

A Cell-penetrating Helical Polymer For siRNA Delivery to Mammalian Cells ⬇️

artículo científico publicado el 29 de mayo de 2012

Azido-galactose outperforms azido-mannose for metabolic labeling and targeting of hepatocellular carcinoma

scientific article published on 01 August 2019

Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure–Functional Selectivity Relationships (SFSRs) and Therapeutic Potential

article

Cancer cell-targeted cisplatin prodrug delivery <i>in vivo via</i> metabolic labeling and bioorthogonal click reaction

artículo científico publicado en 2020

Carbon-silicon switch led to the discovery of novel synthetic cannabinoids with therapeutic effects in a mouse model of multiple sclerosis

artículo científico publicado en 2021

Chain‐Shattering Polymeric Therapeutics with On‐Demand Drug‐Release Capability ⬇️

artículo científico publicado el 6 de mayo de 2013

Design and Discovery of Functionally Selective Serotonin 2C (5-HT2C) Receptor Agonists

artículo científico publicado en 2016

Design and Synthesis of (2-(5-Chloro-2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)cyclopropyl)methanamine as a Selective Serotonin 2C Agonist

artículo científico publicado en 2015

Design and Synthesis of Bitopic 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands

artículo científico publicado en 2020

Dimeric Prodrug Self-Delivery Nanoparticles with Enhanced Drug Loading and Bioreduction Responsiveness for Targeted Cancer Therapy

artículo científico publicado en 2018

Discovery of N-Substituted (2-Phenylcyclopropyl)methylamines as Functionally Selective Serotonin 2C Receptor Agonists for Potential Use as Antipsychotic Medications.

artículo científico publicado en 2017

Drug-Initiated Ring-Opening Polymerization of O-Carboxyanhydrides for the Preparation of Anticancer Drug–Poly(O-carboxyanhydride) Nanoconjugates ⬇️

artículo científico publicado el 27 de febrero de 2013

Dynamic Ureas with Fast and pH-Independent Hydrolytic Kinetics.

artículo científico publicado en 2018

Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models.

artículo científico publicado en 2015

Haloperidol bound D2 dopamine receptor structure inspired the discovery of subtype selective ligands

artículo científico publicado en 2020

High Drug Loading and Sub-Quantitative Loading Efficiency of Polymeric Micelles Driven by Donor-Receptor Coordination Interactions.

artículo científico publicado en 2018

Induction of a higher-ordered architecture in glatiramer acetate improves its biological efficiency in an animal model of multiple sclerosis

artículo científico publicado en 2020

Light‐Responsive Helical Polypeptides Capable of Reducing Toxicity and Unpacking DNA: Toward Nonviral Gene Delivery ⬇️

artículo científico publicado el 5 de julio de 2013

Macrophage-Membrane-Coated Nanoparticles for Tumor-Targeted Chemotherapy

scientific article published on 23 February 2018

Momilactone and Related Diterpenoids as Potential Agricultural Chemicals.

artículo científico publicado en 2018

Nanoscale liposomal formulation of a SYK P-site inhibitor against B-precursor leukemia ⬇️

artículo científico publicado el 8 de abril de 2013

Near IR heptamethine cyanine dye-mediated cancer imaging

artículo científico publicado en 2010

Non‐Viral Gene Delivery via Membrane‐Penetrating, Mannose‐Targeting Supramolecular Self‐Assembled Nanocomplexes ⬇️

artículo científico publicado el 18 de febrero de 2013

Novel Liposomal Azido Mannosamine Lipids on Metabolic Cell Labeling and Imaging via Cu-Free Click Chemistry

artículo científico publicado en 2019

Optimization of 2-phenylcyclopropylmethylamines as selective serotonin 2C receptor agonists and their evaluation as potential antipsychotic agents

artículo científico publicado en 2015

Optimization of P2Y12 Antagonist Ethyl 6-(4-((Benzylsulfonyl)carbamoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate (AZD1283) Led to the Discovery of an Oral Antiplatelet Agent with Improved Druglike Properties

artículo científico publicado en 2019

Preclinical efficacy of the camptothecin-polymer conjugate IT-101 in multiple cancer models

artículo científico publicado en 2006

Proximity-Induced Cooperative Polymerization in "Hinged" Helical Polypeptides

scientific article published on 24 May 2019

Reactive and Bioactive Cationic α‐Helical Polypeptide Template for Nonviral Gene Delivery ⬇️

artículo científico publicado el 7 de diciembre de 2011

Reconfiguring the architectures of cationic helical polypeptides to control non-viral gene delivery ⬇️

artículo científico publicado el 31 de diciembre de 2012

Revisiting the Helical Cooperativity of Synthetic Polypeptides in Solution.

artículo científico publicado en 2017

Size-Dependent Tumor Penetration and in Vivo Efficacy of Monodisperse Drug–Silica Nanoconjugates ⬇️

artículo científico publicado el 12 de febrero de 2013

Supramolecular Assembly of Comb-like Macromolecules Induced by Chemical Reactions that Modulate the Macromolecular Interactions In Situ.

artículo científico publicado en 2017

Synthesis of Water-Soluble Poly(α-hydroxy acids) from Living Ring-Opening Polymerization of O-Benzyl-l-serine Carboxyanhydrides ⬇️

artículo científico publicado el 17 de abril de 2012

The unconventional activation of the muscarinic acetylcholine receptor M4R by diverse ligands

scientific article published on 23 May 2022

Tumor Immunotherapy Using A2A Adenosine Receptor Antagonists

scientific article published on 08 September 2020

Water-Soluble Polypeptides with Elongated, Charged Side Chains Adopt Ultrastable Helical Conformations ⬇️

artículo científico publicado el 13 de septiembre de 2011

We Need 2C but Not 2B: Developing Serotonin 2C (5-HT2C) Receptor Agonists for the Treatment of CNS Disorders.

artículo científico publicado en 2015

Lista de obras de Jianjun Cheng

5-HT2C Agonists Modulate Schizophrenia-Like Behaviors in Mice.

A Cell-penetrating Helical Polymer For siRNA Delivery to Mammalian Cells ⬇️

Azido-galactose outperforms azido-mannose for metabolic labeling and targeting of hepatocellular carcinoma

Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure–Functional Selectivity Relationships (SFSRs) and Therapeutic Potential

Cancer cell-targeted cisplatin prodrug delivery <i>in vivo via</i> metabolic labeling and bioorthogonal click reaction

Carbon-silicon switch led to the discovery of novel synthetic cannabinoids with therapeutic effects in a mouse model of multiple sclerosis

Chain‐Shattering Polymeric Therapeutics with On‐Demand Drug‐Release Capability ⬇️

Design and Discovery of Functionally Selective Serotonin 2C (5-HT2C) Receptor Agonists

Design and Synthesis of (2-(5-Chloro-2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)cyclopropyl)methanamine as a Selective Serotonin 2C Agonist

Design and Synthesis of Bitopic 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands

Dimeric Prodrug Self-Delivery Nanoparticles with Enhanced Drug Loading and Bioreduction Responsiveness for Targeted Cancer Therapy

Discovery of N-Substituted (2-Phenylcyclopropyl)methylamines as Functionally Selective Serotonin 2C Receptor Agonists for Potential Use as Antipsychotic Medications.

Drug-Initiated Ring-Opening Polymerization of O-Carboxyanhydrides for the Preparation of Anticancer Drug–Poly(O-carboxyanhydride) Nanoconjugates ⬇️

Dynamic Ureas with Fast and pH-Independent Hydrolytic Kinetics.

Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models.

Haloperidol bound D2 dopamine receptor structure inspired the discovery of subtype selective ligands

High Drug Loading and Sub-Quantitative Loading Efficiency of Polymeric Micelles Driven by Donor-Receptor Coordination Interactions.

Induction of a higher-ordered architecture in glatiramer acetate improves its biological efficiency in an animal model of multiple sclerosis

Light‐Responsive Helical Polypeptides Capable of Reducing Toxicity and Unpacking DNA: Toward Nonviral Gene Delivery ⬇️

Macrophage-Membrane-Coated Nanoparticles for Tumor-Targeted Chemotherapy

Momilactone and Related Diterpenoids as Potential Agricultural Chemicals.

Nanoscale liposomal formulation of a SYK P-site inhibitor against B-precursor leukemia ⬇️

Near IR heptamethine cyanine dye-mediated cancer imaging

Non‐Viral Gene Delivery via Membrane‐Penetrating, Mannose‐Targeting Supramolecular Self‐Assembled Nanocomplexes ⬇️

Novel Liposomal Azido Mannosamine Lipids on Metabolic Cell Labeling and Imaging via Cu-Free Click Chemistry

Optimization of 2-phenylcyclopropylmethylamines as selective serotonin 2C receptor agonists and their evaluation as potential antipsychotic agents

Optimization of P2Y12 Antagonist Ethyl 6-(4-((Benzylsulfonyl)carbamoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate (AZD1283) Led to the Discovery of an Oral Antiplatelet Agent with Improved Druglike Properties

Preclinical efficacy of the camptothecin-polymer conjugate IT-101 in multiple cancer models

Proximity-Induced Cooperative Polymerization in "Hinged" Helical Polypeptides

Reactive and Bioactive Cationic α‐Helical Polypeptide Template for Nonviral Gene Delivery ⬇️

Reconfiguring the architectures of cationic helical polypeptides to control non-viral gene delivery ⬇️

Revisiting the Helical Cooperativity of Synthetic Polypeptides in Solution.

Size-Dependent Tumor Penetration and in Vivo Efficacy of Monodisperse Drug–Silica Nanoconjugates ⬇️

Supramolecular Assembly of Comb-like Macromolecules Induced by Chemical Reactions that Modulate the Macromolecular Interactions In Situ.

Synthesis of Water-Soluble Poly(α-hydroxy acids) from Living Ring-Opening Polymerization of O-Benzyl-l-serine Carboxyanhydrides ⬇️

The unconventional activation of the muscarinic acetylcholine receptor M4R by diverse ligands

Tumor Immunotherapy Using A2A Adenosine Receptor Antagonists

Water-Soluble Polypeptides with Elongated, Charged Side Chains Adopt Ultrastable Helical Conformations ⬇️

We Need 2C but Not 2B: Developing Serotonin 2C (5-HT2C) Receptor Agonists for the Treatment of CNS Disorders.