Lista de obras - Margaret E Ackerman - Dominio Público Uruguay

A method for high-throughput, sensitive analysis of IgG Fc and Fab glycosylation by capillary electrophoresis

artículo científico publicado en 2014

A modular IgG-scFv bispecific antibody topology

artículo científico publicado en 2009

A multiplexed assay to detect antimicrobial peptides in biological fluids and cell secretions

artículo científico publicado en 2013

A randomized phase 4 study of immunogenicity and safety following monovalent oral type 2 Sabin polio vaccine challenge in IPV-vaccinated children in Lithuania

artículo científico publicado en 2020

A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples

artículo científico publicado en 2010

A33 antigen displays persistent surface expression

artículo científico publicado en 2008

Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition

artículo científico publicado en 2016

Adjuvanted HIV-1 vaccine promotes antibody-dependent phagocytic responses and protects against heterologous SHIV challenge

artículo científico publicado en 2020

An antibody tag-team: driving neutralization through escape

artículo científico publicado en 2014

An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.

artículo científico publicado en 2014

Analysis of complement-mediated lysis of SIV and SIV-infected cells reveals sex differences in vaccine-induced immune responses in Rhesus macaques

article

Antibody Fab-Fc properties outperform titer in predictive models of SIV vaccine-induced protection

scientific article published on 02 May 2019

Antibody humanization by structure-based computational protein design.

artículo científico publicado en 2015

Antibody responses to endemic coronaviruses modulate COVID-19 convalescent plasma functionality

artículo científico publicado en 2020

Antibody subclass skewing predicts enhanced ADCC activity in both natural infection and vaccination

artículo científico publicado en 2012

Antibody-mediated complement activation in pathology and protection

scientific article published on 06 March 2020

Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement

artículo científico publicado en 2018

Biophysical and Functional Characterization of Rhesus Macaque IgG Subclasses.

scientific article published on 13 December 2016

Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.

artículo científico publicado en 2017

Chimeric antigen receptors with human scFvs preferentially induce T cell anti-tumor activity against tumors with high B7H6 expression

artículo científico publicado en 2018

Co-immunization of DNA and Protein in the Same Anatomical Sites Induces Superior Protective Immune Responses against SHIV Challenge

scientific article published on 01 May 2020

Combinatorial resurfacing of Dengue envelope protein domain III antigens selectively ablates epitopes associated with serotype-specific or infection-enhancing antibody responses

artículo científico publicado en 2020

Computationally-driven identification of antibody epitopes.

artículo científico publicado en 2017

Correlates of Immunity to Influenza as Determined by Challenge of Children with Live, Attenuated Influenza Vaccine

artículo científico publicado en 2016

Corrigendum to “A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples”

scholarly article published in Journal of Immunological Methods

Decreased Fc receptor expression on innate immune cells is associated with impaired antibody-mediated cellular phagocytic activity in chronically HIV-1 infected individuals ⬇️

artículo científico publicado el 12 de mayo de 2011

Dendritic cells from the human female reproductive tract rapidly capture and respond to HIV.

artículo científico publicado en 2016

Determining the Phagocytic Activity of Clinical Antibody Samples ⬇️

artículo científico publicado el 30 de noviembre de 2011

Development of unique cytotoxic chimeric antigen receptors based on human scFv targeting B7H6.

artículo científico publicado en 2017

Directed evolution of a yeast-displayed HIV-1 SOSIP gp140 spike protein toward improved expression and affinity for conformational antibodies

artículo científico publicado en 2015

Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology

artículo científico publicado en 2015

Divergent antibody subclass and specificity profiles but not protective HLA-B alleles are associated with variable antibody effector function among HIV-1 controllers

artículo científico publicado en 2013

Diversity of Antiviral IgG Effector Activities Observed in HIV-Infected and Vaccinated Subjects

artículo científico publicado en 2016

Effect of antigen turnover rate and expression level on antibody penetration into tumor spheroids

artículo científico publicado en 2008

Emerging concepts on the role of innate immunity in the prevention and control of HIV infection

artículo científico publicado en 2011

Engineering broadly neutralizing antibodies for HIV prevention and therapy

artículo científico publicado en 2016

Enhanced Phagocytic Activity of HIV-Specific Antibodies Correlates with Natural Production of Immunoglobulins with Skewed Affinity for FcγR2a and FcγR2b ⬇️

artículo científico publicado el 6 de marzo de 2013

Enhancing the Quality of Antibodies to HIV-1 Envelope by GagPol-Specific Th Cells

artículo científico publicado en 2015

Enrichment of high affinity subclasses and glycoforms from serum-derived IgG using FcγRs as affinity ligands

artículo científico publicado en 2018

Erratum: Corrigendum: Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition

artículo científico publicado en 2016

Evidence that CD32a does not mark the HIV-1 latent reservoir.

artículo científico publicado en 2018

Exploiting bias in a non-immune human antibody library to predict antigenicity ⬇️

artículo científico publicado el 9 de septiembre de 2011

Fc Characteristics Mediate Selective Placental Transfer of IgG in HIV-Infected Women

scientific article published on 13 June 2019

Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategies

artículo científico publicado en 2016

Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody

artículo científico publicado en 2020

Features and Functions of Systemic and Mucosal Humoral Immunity Among SARS-CoV-2 Convalescent Individuals

scientific article published on 06 August 2020

Fine epitope signature of antibody neutralization breadth at the HIV-1 envelope CD4-binding site

artículo científico publicado en 2018

Genetically engineered alginate lyase-PEG conjugates exhibit enhanced catalytic function and reduced immunoreactivity

artículo científico publicado en 2011

Going native: Direct high throughput screening of secreted full-length IgG antibodies against cell membrane proteins

artículo científico publicado en 2017

HIV-antibody complexes enhance production of type I interferon by plasmacytoid dendritic cells

artículo científico publicado en 2017

HIV-specific Fc effector function early in infection predicts the development of broadly neutralizing antibodies.

artículo científico publicado en 2018

High-resolution definition of humoral immune response correlates of effective immunity against HIV.

artículo científico publicado en 2018

High-throughput characterization of the functional impact of IgG Fc glycan aberrancy in juvenile idiopathic arthritis.

artículo científico publicado en 2017

High-throughput, multiplexed IgG subclassing of antigen-specific antibodies from clinical samples

artículo científico publicado en 2012

Highly avid magnetic bead capture: an efficient selection method for de novo protein engineering utilizing yeast surface display

artículo científico publicado en 2009

Highly parallel characterization of IgG Fc binding interactions.

artículo científico publicado en 2014

Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies

artículo científico publicado en 2020

Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function

artículo científico publicado en 2014

IgG Binding Characteristics of Rhesus Macaque FcγR

artículo científico publicado en 2016

IgG Fc glycosylation as an axis of humoral immunity in childhood

scientific article published on 24 October 2019

IgG Fc variant cross-reactivity between human and rhesus macaque FcγRs

artículo científico publicado en 2017

IgG3 collaborates with IgG1 and IgA to recruit effector function in RV144 vaccinees

artículo científico publicado en 2020

IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibody

scientific article published on 16 December 2019

Implementation of a three-tiered approach to identify and characterize anti-drug antibodies raised against HIV-specific broadly neutralizing antibodies

scientific article published on 15 February 2020

Increasing the Clinical Potential and Applications of Anti-HIV Antibodies

artículo científico publicado en 2017

Independent evolution of Fc- and Fab-mediated HIV-1-specific antiviral antibody activity following acute infection

artículo científico publicado en 2014

Induction of cross-reactive HIV-1 specific antibody responses by engineered V1V2 immunogens with reduced conformational plasticity

scientific article published on 17 March 2020

Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs

artículo científico publicado en 2017

Intestinal Immune Responses to Type 2 Oral Polio Vaccine (OPV) Challenge in Infants Previously Immunized With Bivalent OPV and Either High-Dose or Standard Inactivated Polio Vaccine.

artículo científico publicado en 2018

Intestinal Immunity to Poliovirus Following Sequential Trivalent Inactivated Polio Vaccine/Bivalent Oral Polio Vaccine and Trivalent Inactivated Polio Vaccine-only Immunization Schedules: Analysis of an Open-label, Randomized, Controlled Trial in Chi

artículo científico publicado en 2018

Intestinal antibody responses to a live oral poliovirus vaccine challenge among adults previously immunized with inactivated polio vaccine in Sweden

artículo científico publicado en 2019

Intestinal antibody responses to two novel live attenuated type 2 oral poliovirus vaccines in healthy adults in Belgium

artículo científico publicado en 2020

Intestinal immunity is a determinant of clearance of poliovirus after oral vaccination

artículo científico publicado en 2014

Knowns and Unknowns of Assaying Antibody-Dependent Cell-Mediated Cytotoxicity Against HIV-1

article

Lack of protection following passive transfer of polyclonal highly functional low-dose non-neutralizing antibodies

artículo científico publicado en 2014

Live attenuated and inactivated influenza vaccines in children

artículo científico publicado en 2014

Longitudinal Antibody Responses in People Who Inject Drugs Infected With Similar Human Immunodeficiency Virus Strains

scientific article published on 01 February 2020

Machine learning methods enable predictive modeling of antibody feature:function relationships in RV144 vaccinees

artículo científico publicado en 2015

Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination

artículo científico publicado en 2020

Mapping the Journey to an HIV Vaccine ⬇️

artículo científico publicado el 25 de julio de 2013

Maternal determinants of infant immunity: Implications for effective immunization and maternal-child health

artículo científico publicado en 2020

Maternal immunization confers protection against neonatal herpes simplex mortality and behavioral morbidity

artículo científico publicado en 2019

Microscale purification of antigen-specific antibodies

artículo científico publicado en 2015

Mind the Gap: How Interspecies Variability in IgG and Its Receptors May Complicate Comparisons of Human and Non-human Primate Effector Function

scientific article published on 08 April 2019

Mining for humoral correlates of HIV control and latent reservoir size

artículo científico publicado en 2020

Mucosal Immunity: The Forgotten Arm of the Immune System: Synopsis of the Pediatric Infectious Disease Society's 2017 Stanley A. Plotkin Lecture in Vaccinology

artículo científico publicado en 2017

Multiplexed Fc array for evaluation of antigen-specific antibody effector profiles

scientific article published on 02 February 2017

Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity

artículo científico publicado en 2013

Noncanonical placental Fc receptors: What is their role in modulating transplacental transfer of maternal IgG?

artículo científico publicado en 2018

Opportunities to exploit non-neutralizing HIV-specific antibody activity

scientific article published on July 2013

Optimization and qualification of a functional anti-drug antibody assay for HIV-1 bnAbs

scientific article published on 07 January 2020

Optimization and qualification of an Fc Array assay for assessments of antibodies against HIV-1/SIV.

artículo científico publicado en 2018

Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge

artículo científico publicado en 2017

Polyfunctional Fc-effector profiles mediated by IgG subclass selection distinguish RV144 and VAX003 vaccines

artículo científico publicado en 2014

Polyfunctional HIV-Specific Antibody Responses Are Associated with Spontaneous HIV Control

artículo científico publicado en 2016

Prospects for engineering HIV-specific antibodies for enhanced effector function and half-life

artículo científico publicado en 2015

Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys

artículo científico publicado en 2015

Protein-based, but not viral vector alone, HIV vaccine boosting drives an IgG1-biased polyfunctional humoral immune response

scientific article published on 18 June 2020

Publisher Correction: Evidence that CD32a does not mark the HIV-1 latent reservoir

artículo científico publicado en 2018

RV144 HIV-1 vaccination impacts post-infection antibody responses

artículo científico publicado en 2020

Recent insights into Fc-mediated effector responses to HIV-1

artículo científico publicado en 2020

Revisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity

artículo científico publicado en 2021

Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV

artículo científico publicado en 2018

SARS-CoV-2 antibody signatures robustly predict diverse antiviral functions relevant for convalescent plasma therapy

artículo científico publicado en 2020

Safety, pharmacokinetics, and immunogenicity of the combination of the broadly neutralizing anti-HIV-1 antibodies 3BNC117 and 10-1074 in healthy adults: A randomized, phase 1 study

artículo científico publicado en 2019

Separation of nonfucosylated antibodies with immobilized FcγRIII receptors

artículo científico publicado en 2013

Stability and CDR composition biases enrich binder functionality landscapes

artículo científico publicado en 2010

Systems serology for decoding infection and vaccine-induced antibody responses to HIV-1

artículo científico publicado en 2019

Systems serology for evaluation of HIV vaccine trials

artículo científico publicado en 2017

The role of Fc receptors in HIV prevention and therapy

artículo científico publicado en 2015

Towards conformational fidelity of a quaternary HIV-1 epitope: computational design and directed evolution of a minimal V1V2 antigen.

artículo científico publicado en 2018

Tracking the Trajectory of Functional Humoral Immune Responses Following Acute HIV Infection

artículo científico publicado en 2020

Vaccine-induced mucosal immunity to poliovirus: analysis of cohorts from an open-label, randomised controlled trial in Latin American infants

artículo científico publicado en 2016

Vector induced skewing of antibody Fc-effector functions

What mAbs tell us about shapes: multiple roads lead to Rome

artículo científico publicado en 2013

Yeast surface display of HIV Env protein variants for the discovery of novel vaccine immunogens

article

λ Light Chain Bias Associated With Enhanced Binding and Function of Anti-HIV Env Glycoprotein Antibodies

artículo científico publicado en 2015

Lista de obras de Margaret E Ackerman

A method for high-throughput, sensitive analysis of IgG Fc and Fab glycosylation by capillary electrophoresis

A modular IgG-scFv bispecific antibody topology

A multiplexed assay to detect antimicrobial peptides in biological fluids and cell secretions

A randomized phase 4 study of immunogenicity and safety following monovalent oral type 2 Sabin polio vaccine challenge in IPV-vaccinated children in Lithuania

A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples

A33 antigen displays persistent surface expression

Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition

Adjuvanted HIV-1 vaccine promotes antibody-dependent phagocytic responses and protects against heterologous SHIV challenge

An antibody tag-team: driving neutralization through escape

An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.

Analysis of complement-mediated lysis of SIV and SIV-infected cells reveals sex differences in vaccine-induced immune responses in Rhesus macaques

Antibody Fab-Fc properties outperform titer in predictive models of SIV vaccine-induced protection

Antibody humanization by structure-based computational protein design.

Antibody responses to endemic coronaviruses modulate COVID-19 convalescent plasma functionality

Antibody subclass skewing predicts enhanced ADCC activity in both natural infection and vaccination

Antibody-mediated complement activation in pathology and protection

Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement

Biophysical and Functional Characterization of Rhesus Macaque IgG Subclasses.

Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.

Chimeric antigen receptors with human scFvs preferentially induce T cell anti-tumor activity against tumors with high B7H6 expression

Co-immunization of DNA and Protein in the Same Anatomical Sites Induces Superior Protective Immune Responses against SHIV Challenge

Combinatorial resurfacing of Dengue envelope protein domain III antigens selectively ablates epitopes associated with serotype-specific or infection-enhancing antibody responses

Computationally-driven identification of antibody epitopes.

Correlates of Immunity to Influenza as Determined by Challenge of Children with Live, Attenuated Influenza Vaccine

Corrigendum to “A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples”

Decreased Fc receptor expression on innate immune cells is associated with impaired antibody-mediated cellular phagocytic activity in chronically HIV-1 infected individuals ⬇️

Dendritic cells from the human female reproductive tract rapidly capture and respond to HIV.

Determining the Phagocytic Activity of Clinical Antibody Samples ⬇️

Development of unique cytotoxic chimeric antigen receptors based on human scFv targeting B7H6.

Directed evolution of a yeast-displayed HIV-1 SOSIP gp140 spike protein toward improved expression and affinity for conformational antibodies

Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology

Divergent antibody subclass and specificity profiles but not protective HLA-B alleles are associated with variable antibody effector function among HIV-1 controllers

Diversity of Antiviral IgG Effector Activities Observed in HIV-Infected and Vaccinated Subjects

Effect of antigen turnover rate and expression level on antibody penetration into tumor spheroids

Emerging concepts on the role of innate immunity in the prevention and control of HIV infection

Engineering broadly neutralizing antibodies for HIV prevention and therapy

Enhanced Phagocytic Activity of HIV-Specific Antibodies Correlates with Natural Production of Immunoglobulins with Skewed Affinity for FcγR2a and FcγR2b ⬇️

Enhancing the Quality of Antibodies to HIV-1 Envelope by GagPol-Specific Th Cells

Enrichment of high affinity subclasses and glycoforms from serum-derived IgG using FcγRs as affinity ligands

Erratum: Corrigendum: Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition

Evidence that CD32a does not mark the HIV-1 latent reservoir.

Exploiting bias in a non-immune human antibody library to predict antigenicity ⬇️

Fc Characteristics Mediate Selective Placental Transfer of IgG in HIV-Infected Women

Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategies

Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody

Features and Functions of Systemic and Mucosal Humoral Immunity Among SARS-CoV-2 Convalescent Individuals

Fine epitope signature of antibody neutralization breadth at the HIV-1 envelope CD4-binding site

Genetically engineered alginate lyase-PEG conjugates exhibit enhanced catalytic function and reduced immunoreactivity

Going native: Direct high throughput screening of secreted full-length IgG antibodies against cell membrane proteins

HIV-antibody complexes enhance production of type I interferon by plasmacytoid dendritic cells

HIV-specific Fc effector function early in infection predicts the development of broadly neutralizing antibodies.

High-resolution definition of humoral immune response correlates of effective immunity against HIV.

High-throughput characterization of the functional impact of IgG Fc glycan aberrancy in juvenile idiopathic arthritis.

High-throughput, multiplexed IgG subclassing of antigen-specific antibodies from clinical samples

Highly avid magnetic bead capture: an efficient selection method for de novo protein engineering utilizing yeast surface display

Highly parallel characterization of IgG Fc binding interactions.

Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies

Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function

IgG Binding Characteristics of Rhesus Macaque FcγR

IgG Fc glycosylation as an axis of humoral immunity in childhood

IgG Fc variant cross-reactivity between human and rhesus macaque FcγRs

IgG3 collaborates with IgG1 and IgA to recruit effector function in RV144 vaccinees

IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibody

Implementation of a three-tiered approach to identify and characterize anti-drug antibodies raised against HIV-specific broadly neutralizing antibodies

Increasing the Clinical Potential and Applications of Anti-HIV Antibodies

Independent evolution of Fc- and Fab-mediated HIV-1-specific antiviral antibody activity following acute infection

Induction of cross-reactive HIV-1 specific antibody responses by engineered V1V2 immunogens with reduced conformational plasticity

Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs

Intestinal Immune Responses to Type 2 Oral Polio Vaccine (OPV) Challenge in Infants Previously Immunized With Bivalent OPV and Either High-Dose or Standard Inactivated Polio Vaccine.

Intestinal Immunity to Poliovirus Following Sequential Trivalent Inactivated Polio Vaccine/Bivalent Oral Polio Vaccine and Trivalent Inactivated Polio Vaccine-only Immunization Schedules: Analysis of an Open-label, Randomized, Controlled Trial in Chi

Intestinal antibody responses to a live oral poliovirus vaccine challenge among adults previously immunized with inactivated polio vaccine in Sweden

Intestinal antibody responses to two novel live attenuated type 2 oral poliovirus vaccines in healthy adults in Belgium

Intestinal immunity is a determinant of clearance of poliovirus after oral vaccination

Knowns and Unknowns of Assaying Antibody-Dependent Cell-Mediated Cytotoxicity Against HIV-1

Lack of protection following passive transfer of polyclonal highly functional low-dose non-neutralizing antibodies

Live attenuated and inactivated influenza vaccines in children

Longitudinal Antibody Responses in People Who Inject Drugs Infected With Similar Human Immunodeficiency Virus Strains

Machine learning methods enable predictive modeling of antibody feature:function relationships in RV144 vaccinees

Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination