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Lista de obras de Alex J Hughes

Engineering kidney developmental trajectory using culture boundary conditions

Enhancing single-cell western blotting sensitivity using diffusive analyte blotting and antibody conjugate amplification

Highly-parallel production of designer organoids by mosaic patterning of progenitors

Independent control over cell patterning and adhesion on hydrogel substrates for tissue interface mechanobiology

Kinomorphs: Shape-shifting tissues for developmental engineering

Measurement of adhesion and traction of cells at high yield (MATCHY) reveals an energetic ratchet driving nephron condensation

Nephron progenitors rhythmically alternate between renewal and differentiation phases that synchronize with kidney branching morphogenesis

Quantius: Generic, high-fidelity human annotation of scientific images at 105-clicks-per-hour

Rho/ROCK activity tunes cell compartment segregation and differentiation in nephron-forming niches

Single-Cell Spatial Mapping of Human Kidney Development Reveals the Critical Role of the Local Microenvironment in Cell Fate Decisions

Systematically quantifying morphological features reveals constraints on organoid phenotypes

The developing kidney actively negotiates geometric packing conflicts to avoid defects

Tissue Folding by Mechanical Compaction of the Mesenchyme

Tubule jamming in the developing mouse kidney creates cyclical mechanical stresses in nephron-forming niches

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