Lista de obras - Paul M Yen - Dominio Público Uruguay

9-cis retinoic acid regulation of rat growth hormone gene expression: potential roles of multiple nuclear hormone receptors.

artículo científico publicado en 1994

A case of spurious hypercalcitoninemia: a cautionary tale on the use of plasma calcitonin assays in the screening of patients with thyroid nodules for neoplasia.

artículo científico publicado en 2001

A clinician's guide to understanding resistance to thyroid hormone due to receptor mutations in the TRα and TRβ isoforms.

artículo científico publicado en 2017

A peptide inhibitor derived from p55PIK phosphatidylinositol 3-kinase regulatory subunit: a novel cancer therapy.

artículo científico publicado en 2008

Aberrant alternative splicing of thyroid hormone receptor in a TSH-secreting pituitary tumor is a mechanism for hormone resistance

artículo científico publicado en 2001

Adjunctive β2-agonist treatment reduces glycogen independently of receptor-mediated acid α-glucosidase uptake in the limb muscles of mice with Pompe disease

artículo científico publicado en 2014

An Inhibitory Region of the DNA-Binding Domain of Thyroid Hormone Receptor Blocks Hormone-Dependent Transactivation ⬇️

artículo científico publicado el 1 de enero de 1998

An integrative approach identified genes associated with drug response in gastric cancer.

artículo científico publicado en 2015

Anti-estrogenic compounds increase prolactin and growth hormone synthesis in clonal strains of rat pituitary cells

artículo científico publicado el 1 de octubre de 1977

Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice.

artículo científico publicado en 2014

Cell cycle-dependent expression of thyroid hormone receptor-beta is a mechanism for variable hormone sensitivity

artículo científico publicado en 2004

Changes in Hepatic TRβ Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model.

artículo científico publicado en 2017

Changes in macroautophagy, chaperone-mediated autophagy, and mitochondrial metabolism in murine skeletal and cardiac muscle during aging.

artículo científico publicado en 2017

Characterization and tissue expression of multiple triiodothyronine receptor-auxiliary proteins and their relationship to the retinoid X-receptors

artículo científico publicado en 1993

Classical nuclear hormone receptor activity as a mediator of complex biological responses: a look at health and disease.

artículo científico

Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism

artículo científico publicado en 2014

Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism.

artículo científico publicado en 2014

Comparative analysis of small molecules and histone substrate analogues as LSD1 lysine demethylase inhibitors

artículo científico publicado en 2010

Corrigendum to "Short chain fatty acids induce UCP2-mediated autophagy in hepatic cells" [Biochem. Biophys. Res. Commun. 480 (2016) 461-467]

scientific article published on 26 November 2016

Desensitization and Incomplete Recovery of Hepatic Target Genes After Chronic Thyroid Hormone Treatment and Withdrawal in Male Adult Mice

artículo científico publicado en 2016

Differential AMPK phosphorylation by glucagon and metformin regulates insulin signaling in human hepatic cells.

artículo científico publicado en 2014

Differential expression of thyroid hormone receptor isoforms in neurons and astroglial cells.

artículo científico publicado en 1994

Direct effects of thyroid hormones on hepatic lipid metabolism.

artículo científico publicado en 2018

Do clinical manifestations of resistance to thyroid hormone correlate with the functional alteration of the corresponding mutant thyroid hormone-beta receptors? ⬇️

artículo científico publicado el 1 de noviembre de 1995

Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism

artículo científico publicado en 2011

Dynamic shuttling and intranuclear mobility of nuclear hormone receptors.

artículo científico publicado en 2002

Editorial: studying hormonal regulation by microarrays: distinguishing the trees from the forest

scientific article published on 01 February 2005

Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice.

artículo científico publicado en 2003

Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, stimulates hepatic autophagy and lipid clearance.

artículo científico publicado en 2014

Expression and Hormonal Regulation of Coactivator and Corepressor Genes ⬇️

artículo científico publicado el 1 de mayo de 1998

Extreme Thyroid Hormone Resistance in a Patient with a Novel Truncated TR Mutant ⬇️

artículo científico publicado el 1 de noviembre de 2001

Factors that enhance Escherichia coli-expressed TR beta binding to T3 and DNA

artículo científico publicado en 1995

Genetic and bioinformatic analyses of the expression and function of PI3K regulatory subunit PIK3R3 in an Asian patient gastric cancer library

artículo científico publicado en 2012

Germline and somatic thyroid hormone receptor mutations in man.

artículo científico publicado en 2003

Glucocorticoid receptor binding to rat liver nuclei occurs without nuclear transport.

artículo científico publicado en 1993

Graves' disease after interleukin-2 therapy in a patient with human immunodeficiency virus infection

artículo científico publicado en 2004

Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition

artículo científico publicado en 2015

Hepatic FTO expression is increased in NASH and its silencing attenuates palmitic acid-induced lipotoxicity

artículo científico publicado en 2016

Hepatic mitochondrial dysfunction is a feature of Glycogen Storage Disease Type Ia (GSDIa).

artículo científico publicado en 2017

Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation

artículo científico publicado en 2016

Increasing Dietary Medium-Chain Fatty Acid Ratio Mitigates High-fat Diet-Induced Non-Alcoholic Steatohepatitis by Regulating Autophagy

artículo científico publicado en 2017

Induction of autophagy improves hepatic lipid metabolism in glucose-6-phosphatase deficiency

artículo científico publicado en 2015

Interactions of estrogen- and thyroid hormone receptors on a progesterone receptor estrogen response element (ERE) sequence: a comparison with the vitellogenin A2 consensus ERE.

artículo científico publicado en 1997

Intracellular proteolytic cleavage of 9-cis-retinoic acid receptor alpha by cathepsin L-type protease is a potential mechanism for modulating thyroid hormone action

artículo científico publicado en 1998

Isoform-specific retinoid-X receptor (RXR) antibodies detect differential expression of RXR proteins in the pituitary gland

artículo científico publicado en 1995

Ligand-induced recruitment of a histone deacetylase in the negative-feedback regulation of the thyrotropin beta gene

artículo científico publicado en 1999

Loss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cells

artículo científico publicado en 2016

Metabolomic analysis shows differential hepatic effects of T2 and T3 in rats after short-term feeding with high fat diet.

artículo científico publicado en 2017

Microarray analysis of knockout mice identifies cyclin D2 as a possible mediator for the action of thyroid hormone during the postnatal development of the cerebellum.

artículo científico publicado en 2003

Molecular basis of resistance to thyroid hormone.

artículo científico publicado en 2003

Molecular mechanisms of dominant negative activity by nuclear hormone receptors.

artículo científico publicado en 1994

Mutant and wild-type androgen receptors exhibit cross-talk on androgen-, glucocorticoid-, and progesterone-mediated transcription

scientific article published on 01 February 1997

Negative regulation of TSHalpha target gene by thyroid hormone involves histone acetylation and corepressor complex dissociation

artículo científico publicado en 2009

New insights into thyroid hormone action.

artículo científico publicado en 2007

New insights on the mechanism(s) of the dominant negative effect of mutant thyroid hormone receptor in generalized resistance to thyroid hormone.

artículo científico publicado en 1992

PI3K stimulates DNA synthesis and cell-cycle progression via its p55PIK regulatory subunit interaction with PCNA.

artículo científico publicado en 2013

Pharmacological Inhibition of Lysosomal Activity as a Method For Monitoring Thyroid Hormone-induced Autophagic Flux in Mammalian Cells In Vitro.

artículo científico publicado en 2018

Physiological and Metabolic Changes During the Transition from Hyperthyroidism to Euthyroidism in Graves' Disease.

artículo científico publicado en 2016

Reciprocal Crosstalk Between Autophagic and Endocrine Signaling in Metabolic Homeostasis

artículo científico publicado en 2016

Recombinant human thyrotropin for the diagnosis and treatment of a highly functional metastatic struma ovarii

artículo científico publicado en 2000

Region-specific anti-thyroid hormone receptor (TR) antibodies detect changes in TR structure due to ligand-binding and dimerization.

artículo científico publicado en 1993

Renal endoplasmic reticulum stress is coupled to impaired autophagy in a mouse model of GSD Ia.

artículo científico publicado en 2017

Resistance to thyroid hormone in a patient without thyroid hormone receptor mutations.

artículo científico publicado en 2002

Resveratrol induces insulin gene expression in mouse pancreatic α-cells.

artículo científico publicado en 2013

Role of the asialoglycoprotein receptor in binding and entry of hepatitis C virus structural proteins in cultured human hepatocytes.

artículo científico publicado en 2003

Role of thyroid hormone in hepatic gene regulation, chromatin remodeling, and autophagy.

artículo científico publicado en 2017

Roles of 3,5,3'-triiodothyronine and deoxyribonucleic acid binding on thyroid hormone receptor complex formation

scientific article published on 01 March 1994

Short chain fatty acids increase prolactin and growth hormone production and alter cell morphology in the GH3 strain of rat pituitary cells.

artículo científico publicado en 1981

Short chain fatty acids induce UCP2-mediated autophagy in hepatic cells.

artículo científico publicado en 2016

Somatic Mutation of TRβ Can Cause a Defect in Negative Regulation of TSH in a TSH-Secreting Pituitary Tumor ⬇️

artículo científico publicado el 1 de noviembre de 2001

Species Differences in Cardiac Thyroid Hormone Receptor Isoforms Protein Abundance ⬇️

artículo científico publicado el 1 de noviembre de 1997

Studies of molecular mechanisms associated with increased deiodinase 3 expression in a case of consumptive hypothyroidism.

artículo científico publicado en 2014

Studies on the repression of basal transcription (silencing) by artificial and natural human thyroid hormone receptor-beta mutants

scientific article published on 01 July 1995

T3 or not T3--the slings and arrows of outrageous TR function

scientific article published on 01 February 1996

TSHβv-A New Bone to Pick

artículo científico publicado en 2016

The isoform-specific expression of the tri-iodothyronine receptor in osteoblasts and osteoclasts

scientific article published on 01 May 1996

The rat thyroid hormone receptor (TR) Deltabeta3 displays cell-, TR isoform-, and thyroid hormone response element-specific actions

artículo científico publicado en 2007

Thyroid Hormone Response Elements Differentially Modulate the Interactions of Thyroid Hormone Receptors with Two Receptor Binding Domains in the Steroid Receptor Coactivator-1 ⬇️

artículo científico publicado el 21 de agosto de 1998

Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature.

artículo científico publicado en 2017

Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle.

artículo científico publicado en 2015

Thyroid disorders, noncommunicable diseases that gravely impact public health: a commentary and statement by the Advisory Board of the World Thyroid Federation

artículo científico publicado en 2012

Thyroid hormone action at the cellular, genomic and target gene levels.

artículo científico publicado en 2006

Thyroid hormone induction of mitochondrial activity is coupled to mitophagy via ROS-AMPK-ULK1 signaling

scientific journal article

Thyroid hormone negatively regulates CDX2 and SOAT2 mRNA expression via induction of miRNA-181d in hepatic cells

artículo científico publicado en 2013

Thyroid hormone regulation of hepatic genes in vivo detected by complementary DNA microarray.

artículo científico publicado en 2000

Thyroid hormone regulation of hepatic lipid and carbohydrate metabolism

artículo científico publicado en 2014

Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy ⬇️

artículo científico publicado el 11 de junio de 2012

Thyroid hormone-mediated autophagy and mitochondrial turnover in NAFLD

artículo científico publicado en 2016

Thyroid hormones and 3,5-diiodothyropropionic acid: new keys for new locks

scientific article published on 01 April 2006

Transgenic targeting of a dominant negative corepressor to liver blocks basal repression by thyroid hormone receptor and increases cell proliferation

scientific journal article

Unliganded TRs regulate growth and developmental timing during early embryogenesis: evidence for a dual function mechanism of TR action

artículo científico publicado en 2015

Waterboarding is not torture: a physician's response

artículo científico publicado en 2008

p62, A TFIIH subunit, directly interacts with thyroid hormone receptor and enhances T3-mediated transcription

artículo científico publicado en 2005

β-Adrenergic agonist and antagonist regulation of autophagy in HepG2 cells, primary mouse hepatocytes, and mouse liver

artículo científico publicado en 2014

Lista de obras de Paul M Yen

9-cis retinoic acid regulation of rat growth hormone gene expression: potential roles of multiple nuclear hormone receptors.

A case of spurious hypercalcitoninemia: a cautionary tale on the use of plasma calcitonin assays in the screening of patients with thyroid nodules for neoplasia.

A clinician's guide to understanding resistance to thyroid hormone due to receptor mutations in the TRα and TRβ isoforms.

A peptide inhibitor derived from p55PIK phosphatidylinositol 3-kinase regulatory subunit: a novel cancer therapy.

Aberrant alternative splicing of thyroid hormone receptor in a TSH-secreting pituitary tumor is a mechanism for hormone resistance

Adjunctive β2-agonist treatment reduces glycogen independently of receptor-mediated acid α-glucosidase uptake in the limb muscles of mice with Pompe disease

An Inhibitory Region of the DNA-Binding Domain of Thyroid Hormone Receptor Blocks Hormone-Dependent Transactivation ⬇️

An integrative approach identified genes associated with drug response in gastric cancer.

Anti-estrogenic compounds increase prolactin and growth hormone synthesis in clonal strains of rat pituitary cells

Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice.

Cell cycle-dependent expression of thyroid hormone receptor-beta is a mechanism for variable hormone sensitivity

Changes in Hepatic TRβ Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model.

Changes in macroautophagy, chaperone-mediated autophagy, and mitochondrial metabolism in murine skeletal and cardiac muscle during aging.

Characterization and tissue expression of multiple triiodothyronine receptor-auxiliary proteins and their relationship to the retinoid X-receptors

Classical nuclear hormone receptor activity as a mediator of complex biological responses: a look at health and disease.

Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism

Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism.

Comparative analysis of small molecules and histone substrate analogues as LSD1 lysine demethylase inhibitors

Corrigendum to "Short chain fatty acids induce UCP2-mediated autophagy in hepatic cells" [Biochem. Biophys. Res. Commun. 480 (2016) 461-467]

Desensitization and Incomplete Recovery of Hepatic Target Genes After Chronic Thyroid Hormone Treatment and Withdrawal in Male Adult Mice

Differential AMPK phosphorylation by glucagon and metformin regulates insulin signaling in human hepatic cells.

Differential expression of thyroid hormone receptor isoforms in neurons and astroglial cells.

Direct effects of thyroid hormones on hepatic lipid metabolism.

Do clinical manifestations of resistance to thyroid hormone correlate with the functional alteration of the corresponding mutant thyroid hormone-beta receptors? ⬇️

Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism

Dynamic shuttling and intranuclear mobility of nuclear hormone receptors.

Editorial: studying hormonal regulation by microarrays: distinguishing the trees from the forest

Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice.

Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, stimulates hepatic autophagy and lipid clearance.

Expression and Hormonal Regulation of Coactivator and Corepressor Genes ⬇️

Extreme Thyroid Hormone Resistance in a Patient with a Novel Truncated TR Mutant ⬇️

Factors that enhance Escherichia coli-expressed TR beta binding to T3 and DNA

Genetic and bioinformatic analyses of the expression and function of PI3K regulatory subunit PIK3R3 in an Asian patient gastric cancer library

Germline and somatic thyroid hormone receptor mutations in man.

Glucocorticoid receptor binding to rat liver nuclei occurs without nuclear transport.

Graves' disease after interleukin-2 therapy in a patient with human immunodeficiency virus infection

Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition

Hepatic FTO expression is increased in NASH and its silencing attenuates palmitic acid-induced lipotoxicity

Hepatic mitochondrial dysfunction is a feature of Glycogen Storage Disease Type Ia (GSDIa).

Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation

Increasing Dietary Medium-Chain Fatty Acid Ratio Mitigates High-fat Diet-Induced Non-Alcoholic Steatohepatitis by Regulating Autophagy

Induction of autophagy improves hepatic lipid metabolism in glucose-6-phosphatase deficiency

Interactions of estrogen- and thyroid hormone receptors on a progesterone receptor estrogen response element (ERE) sequence: a comparison with the vitellogenin A2 consensus ERE.

Intracellular proteolytic cleavage of 9-cis-retinoic acid receptor alpha by cathepsin L-type protease is a potential mechanism for modulating thyroid hormone action

Isoform-specific retinoid-X receptor (RXR) antibodies detect differential expression of RXR proteins in the pituitary gland

Ligand-induced recruitment of a histone deacetylase in the negative-feedback regulation of the thyrotropin beta gene

Loss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cells

Metabolomic analysis shows differential hepatic effects of T2 and T3 in rats after short-term feeding with high fat diet.

Microarray analysis of knockout mice identifies cyclin D2 as a possible mediator for the action of thyroid hormone during the postnatal development of the cerebellum.

Molecular basis of resistance to thyroid hormone.

Molecular mechanisms of dominant negative activity by nuclear hormone receptors.

Mutant and wild-type androgen receptors exhibit cross-talk on androgen-, glucocorticoid-, and progesterone-mediated transcription

Negative regulation of TSHalpha target gene by thyroid hormone involves histone acetylation and corepressor complex dissociation

New insights into thyroid hormone action.

New insights on the mechanism(s) of the dominant negative effect of mutant thyroid hormone receptor in generalized resistance to thyroid hormone.

PI3K stimulates DNA synthesis and cell-cycle progression via its p55PIK regulatory subunit interaction with PCNA.

Pharmacological Inhibition of Lysosomal Activity as a Method For Monitoring Thyroid Hormone-induced Autophagic Flux in Mammalian Cells In Vitro.

Physiological and Metabolic Changes During the Transition from Hyperthyroidism to Euthyroidism in Graves' Disease.

Reciprocal Crosstalk Between Autophagic and Endocrine Signaling in Metabolic Homeostasis

Recombinant human thyrotropin for the diagnosis and treatment of a highly functional metastatic struma ovarii

Region-specific anti-thyroid hormone receptor (TR) antibodies detect changes in TR structure due to ligand-binding and dimerization.

Renal endoplasmic reticulum stress is coupled to impaired autophagy in a mouse model of GSD Ia.

Resistance to thyroid hormone in a patient without thyroid hormone receptor mutations.

Resveratrol induces insulin gene expression in mouse pancreatic α-cells.

Role of the asialoglycoprotein receptor in binding and entry of hepatitis C virus structural proteins in cultured human hepatocytes.

Role of thyroid hormone in hepatic gene regulation, chromatin remodeling, and autophagy.

Roles of 3,5,3'-triiodothyronine and deoxyribonucleic acid binding on thyroid hormone receptor complex formation

Short chain fatty acids increase prolactin and growth hormone production and alter cell morphology in the GH3 strain of rat pituitary cells.

Short chain fatty acids induce UCP2-mediated autophagy in hepatic cells.

Somatic Mutation of TRβ Can Cause a Defect in Negative Regulation of TSH in a TSH-Secreting Pituitary Tumor ⬇️

Species Differences in Cardiac Thyroid Hormone Receptor Isoforms Protein Abundance ⬇️

Studies of molecular mechanisms associated with increased deiodinase 3 expression in a case of consumptive hypothyroidism.

Studies on the repression of basal transcription (silencing) by artificial and natural human thyroid hormone receptor-beta mutants

T3 or not T3--the slings and arrows of outrageous TR function

TSHβv-A New Bone to Pick

The isoform-specific expression of the tri-iodothyronine receptor in osteoblasts and osteoclasts

The rat thyroid hormone receptor (TR) Deltabeta3 displays cell-, TR isoform-, and thyroid hormone response element-specific actions

Thyroid Hormone Response Elements Differentially Modulate the Interactions of Thyroid Hormone Receptors with Two Receptor Binding Domains in the Steroid Receptor Coactivator-1 ⬇️

Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature.