Lista de obras - Gilda Tachedjian - Dominio Público Uruguay

4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention.

artículo científico publicado en 2007

A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats

artículo científico publicado en 2019

Alteration of the proline at position 7 of the HIV-1 spacer peptide p1 suppresses viral infectivity in a strain dependent manner

artículo científico publicado en 2007

Analysis of mutations and suppressors affecting interactions between the subunits of the HIV type 1 reverse transcriptase

artículo científico publicado en 2000

Analysis of the contribution of reverse transcriptase and integrase proteins to retroviral RNA dimer conformation

artículo científico publicado en 2005

Anti-HIV-1 Activity of Lactic Acid in Human Cervicovaginal Fluid.

artículo científico publicado en 2018

Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis

artículo científico publicado en 2015

Antiretroviral compounds: mechanisms underlying failure of HAART to eradicate HIV-1.

artículo científico publicado en 2005

Antiviral strategies in chronic hepatitis B virus infection: II. Inhibition of duck hepatitis B virus in vitro using conventional antiviral agents and supercoiled-DNA active compounds.

artículo científico publicado en 1990

Bats and Reverse Transcribing RNA and DNA Viruses

Bats and Rodents Shape Mammalian Retroviral Phylogeny

artículo científico publicado en 2015

Biology of mucosally transmitted sexual infection-translating the basic science into novel HIV intervention: a workshop summary

artículo científico publicado en 2012

Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT.

artículo científico publicado en 2007

Clinical effects and in vitro studies of trifluorothymidine combined with interferon-alpha for treatment of drug-resistant and -sensitive herpes simplex virus infections

artículo científico publicado el 1 de julio de 1992

Contraction of the type I IFN locus and unusual constitutive expression of IFN-α in bats

artículo científico publicado en 2016

Coresistance to zidovudine and foscarnet is associated with multiple mutations in the human immunodeficiency virus type 1 reverse transcriptase

artículo científico publicado en 1998

Critical Review: Mechanisms of HIV Transmission in Depo-Provera Users: The Likely Role of Hypoestrogenism

artículo científico publicado en 2016

Current and Emerging Drug Targets for Human Immunodeficiency Virus

artículo científico publicado en 2015

Decoding the membrane activity of the cyclotide kalata B1: the importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities

artículo científico publicado en 2011

Differential evolution of antiretroviral restriction factors in pteropid bats as revealed by APOBEC3 gene complexity

artículo científico publicado en 2018

Dimerization of human immunodeficiency virus type 1 reverse transcriptase as an antiviral target.

artículo científico publicado en 2006

Discovery of retroviral homologs in bats: implications for the origin of mammalian gammaretroviruses

artículo científico publicado en 2012

Drug Resistant SIV Strains Carrying Higher-Fidelity K65R and Q151N Reverse Transcriptase Mutations Are Less Fit In Vivo

article by Sarah B. Lloyd et al published October 2014 in AIDS Research and Human Retroviruses

Efavirenz enhances the proteolytic processing of an HIV-1 pol polyprotein precursor and reverse transcriptase homodimer formation

artículo científico publicado en 2005

Effect of Reverse Transcriptase Inhibitors and Mutations on the Low-Cost Cavidi Reverse Transcriptase Viral Load Assay

artículo científico publicado en 2009

Enhancement of human immunodeficiency virus type 1 replication is not intrinsic to all polyanion-based microbicides.

scientific article published on 15 June 2009

Evaluation of a low cost reverse transcriptase assay for plasma HIV-1 viral load monitoring

artículo científico publicado en 2005

Fragment Based Strategies for Discovery of Novel HIV-1 Reverse Transcriptase and Integrase Inhibitors

artículo científico publicado en 2015

HIV-1 infection of T cells and macrophages are differentially modulated by virion-associated Hck: a Nef-dependent phenomenon

artículo científico publicado en 2013

High fidelity simian immunodeficiency virus reverse transcriptase mutants have impaired replication in vitro and in vivo

artículo científico publicado en 2016

Host and Viral Proteins Modulating Ebola and Marburg Virus Egress

artículo científico publicado en 2019

Host-pathogen interactions of retroviruses

artículo científico publicado en 2012

Identification of diverse full-length endogenous betaretroviruses in megabats and microbats

artículo científico publicado en 2013

Identification of diverse groups of endogenous gammaretroviruses in mega- and microbats

artículo científico publicado en 2012

Identification of mechanistically distinct inhibitors of HIV-1 reverse transcriptase through fragment screening.

artículo científico publicado en 2015

Identification of residues involved in NS2 homodimerization and elucidation of their impact on the HCV life cycle

artículo científico publicado en 2011

Impact of residues in the nonnucleoside reverse transcriptase inhibitor binding pocket on HIV-1 reverse transcriptase heterodimer stability

artículo científico publicado en 2008

Increasing prevalence of K65K and K66K in HIV-1 subtype B reverse transcriptase.

artículo científico publicado en 2016

Infectious KoRV-related retroviruses circulating in Australian bats

scientific article published on 13 April 2020

Investigation of Topoisomerase Inhibitors for Activity against Human Immunodeficiency Virus: Inhibition by Coumermycin A1

Lactic Acid, a Vaginal Microbiota Metabolite, Elicits an Anti-inflammatory Response from Vaginal and Cervical Epithelial Cells

Long-term foscarnet therapy not associated with the development of foscarnet-resistant human immunodeficiency virus type 1 in an acquired immunodeficiency syndrome patient.

artículo científico publicado en 1994

Maturation of the HIV reverse transcription complex: putting the jigsaw together

artículo científico publicado en 2009

Mechanisms of inhibition of HIV replication by non-nucleoside reverse transcriptase inhibitors

artículo científico publicado en 2008

Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules

artículo científico publicado en 2002

Molecular dissection of an inhibitor targeting the HIV integrase dependent preintegration complex nuclear import

Mutations that abrogate human immunodeficiency virus type 1 reverse transcriptase dimerization affect maturation of the reverse transcriptase heterodimer

artículo científico publicado en 2005

N348I in HIV-1 reverse transcriptase counteracts the synergy between zidovudine and nevirapine

artículo científico publicado en 2012

N348I in HIV-1 reverse transcriptase decreases susceptibility to tenofovir and etravirine in combination with other resistance mutations

artículo científico publicado en 2010

N348I in reverse transcriptase provides a genetic pathway for HIV-1 to select thymidine analogue mutations and mutations antagonistic to thymidine analogue mutations

artículo científico publicado en 2010

N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance

artículo científico publicado en 2007

No association between XMRV or related gammaretroviruses in Australian prostate cancer patients

artículo científico publicado en 2013

Nonnucleoside Reverse Transcriptase Inhibitors Reduce HIV-1 Production from Latently Infected Resting CD4+ T Cells following Latency Reversal.

artículo científico publicado en 2016

Nonnucleoside reverse transcriptase inhibitors are chemical enhancers of dimerization of the HIV type 1 reverse transcriptase

artículo científico publicado en 2001

Oxazole-benzenesulfonamide derivatives inhibit HIV-1 reverse transcriptase interaction with cellular eEF1A and reduce viral replication

scholarly article by Daniel J Rawle et al published 27 March 2019 in Journal of Virology

Phosphatidylethanolamine binding is a conserved feature of cyclotide-membrane interactions

artículo científico publicado en 2012

Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-Pol

artículo científico publicado en 2006

Relationship between enzyme activity and dimeric structure of recombinant HIV-1 reverse transcriptase

article

Reverse transcriptase mutations in sequential HIV-1 isolates in a patient with AIDS.

artículo científico publicado en 1995

Role of RNase H Activity in NRTI/NNRTI Drug Resistance

Role of residues in the tryptophan repeat motif for HIV-1 reverse transcriptase dimerization

artículo científico publicado en 2003

SPL7013 Gel (VivaGel®) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humans

artículo científico publicado en 2011

Sensitive assessment of the virologic outcomes of stopping and restarting non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy

artículo científico publicado en 2013

Silent mutations at codons 65 and 66 in reverse transcriptase alleviate indel formation and restore fitness in subtype B HIV-1 containing D67N and K70R drug resistance mutations

artículo científico publicado en 2015

Structure activity relationship of dendrimer microbicides with dual action antiviral activity

artículo científico publicado en 2010

Synergistic Inhibition of Human Immunodeficiency Virus Type 1 in vitro by Interferon Alpha and Coumermycin A1

Synergistic inhibition of human immunodefficiency virus type 1 in vitro by coumermycin A1 and human leukocyte interferon

scientific article published in 1991

Targeting Human Immunodeficiency Virus Type 1 Assembly, Maturation and Budding

The NRTIs lamivudine, stavudine and zidovudine have reduced HIV-1 inhibitory activity in astrocytes

artículo científico publicado en 2013

The effect of NNRTIs on HIV reverse transcriptase dimerization.

artículo científico publicado en 2003

The human immunodeficiency virus type 1 nonnucleoside reverse transcriptase inhibitor resistance mutation I132M confers hypersensitivity to nucleoside analogs

artículo científico publicado en 2009

The implausible "in vivo" role of hydrogen peroxide as an antimicrobial factor produced by vaginal microbiota

artículo científico publicado en 2018

The packaging and maturation of the HIV-1 Pol proteins

artículo científico publicado en 2005

The role of lactic acid production by probiotic Lactobacillus species in vaginal health

artículo científico publicado en 2017

The seventh (and last?) International Microbicides Conference: from discovery to delivery

artículo científico publicado en 2013

Ubisol-Aqua: coenzyme Q10 prevents antiretroviral toxic neuropathy in an in vitro model

artículo científico publicado en 2010

Vaginal Concentrations of Lactic Acid Potently Inactivate HIV-1 Compared to Short Chain Fatty Acids Present During Bacterial Vaginosis

Vaginal concentrations of lactic acid potently inactivate HIV

scientific article published on 08 May 2013

Virological significance, prevalence and genetic basis of hypersusceptibility to nonnucleoside reverse transcriptase inhibitors

artículo científico publicado en 2004

Virucidal activity of the dendrimer microbicide SPL7013 against HIV-1.

artículo científico publicado en 2011

Why Do We Need New Drug Classes for HIV Treatment and Prevention?

artículo científico

Zidovudine resistance is suppressed by mutations conferring resistance of human immunodeficiency virus type 1 to foscarnet.

artículo científico publicado en 1996

Lista de obras de Gilda Tachedjian

4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention.

A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats

Alteration of the proline at position 7 of the HIV-1 spacer peptide p1 suppresses viral infectivity in a strain dependent manner

Analysis of mutations and suppressors affecting interactions between the subunits of the HIV type 1 reverse transcriptase

Analysis of the contribution of reverse transcriptase and integrase proteins to retroviral RNA dimer conformation

Anti-HIV-1 Activity of Lactic Acid in Human Cervicovaginal Fluid.

Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis

Antiretroviral compounds: mechanisms underlying failure of HAART to eradicate HIV-1.

Antiviral strategies in chronic hepatitis B virus infection: II. Inhibition of duck hepatitis B virus in vitro using conventional antiviral agents and supercoiled-DNA active compounds.

Bats and Reverse Transcribing RNA and DNA Viruses

Bats and Rodents Shape Mammalian Retroviral Phylogeny

Biology of mucosally transmitted sexual infection-translating the basic science into novel HIV intervention: a workshop summary

Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT.

Clinical effects and in vitro studies of trifluorothymidine combined with interferon-alpha for treatment of drug-resistant and -sensitive herpes simplex virus infections

Contraction of the type I IFN locus and unusual constitutive expression of IFN-α in bats

Coresistance to zidovudine and foscarnet is associated with multiple mutations in the human immunodeficiency virus type 1 reverse transcriptase

Critical Review: Mechanisms of HIV Transmission in Depo-Provera Users: The Likely Role of Hypoestrogenism

Current and Emerging Drug Targets for Human Immunodeficiency Virus

Decoding the membrane activity of the cyclotide kalata B1: the importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities

Differential evolution of antiretroviral restriction factors in pteropid bats as revealed by APOBEC3 gene complexity

Dimerization of human immunodeficiency virus type 1 reverse transcriptase as an antiviral target.

Discovery of retroviral homologs in bats: implications for the origin of mammalian gammaretroviruses

Drug Resistant SIV Strains Carrying Higher-Fidelity K65R and Q151N Reverse Transcriptase Mutations Are Less Fit In Vivo

Efavirenz enhances the proteolytic processing of an HIV-1 pol polyprotein precursor and reverse transcriptase homodimer formation

Effect of Reverse Transcriptase Inhibitors and Mutations on the Low-Cost Cavidi Reverse Transcriptase Viral Load Assay

Enhancement of human immunodeficiency virus type 1 replication is not intrinsic to all polyanion-based microbicides.

Evaluation of a low cost reverse transcriptase assay for plasma HIV-1 viral load monitoring

Fragment Based Strategies for Discovery of Novel HIV-1 Reverse Transcriptase and Integrase Inhibitors

HIV-1 infection of T cells and macrophages are differentially modulated by virion-associated Hck: a Nef-dependent phenomenon

High fidelity simian immunodeficiency virus reverse transcriptase mutants have impaired replication in vitro and in vivo

Host and Viral Proteins Modulating Ebola and Marburg Virus Egress

Host-pathogen interactions of retroviruses

Identification of diverse full-length endogenous betaretroviruses in megabats and microbats

Identification of diverse groups of endogenous gammaretroviruses in mega- and microbats

Identification of mechanistically distinct inhibitors of HIV-1 reverse transcriptase through fragment screening.

Identification of residues involved in NS2 homodimerization and elucidation of their impact on the HCV life cycle

Impact of residues in the nonnucleoside reverse transcriptase inhibitor binding pocket on HIV-1 reverse transcriptase heterodimer stability

Increasing prevalence of K65K and K66K in HIV-1 subtype B reverse transcriptase.

Infectious KoRV-related retroviruses circulating in Australian bats

Investigation of Topoisomerase Inhibitors for Activity against Human Immunodeficiency Virus: Inhibition by Coumermycin A1

Lactic Acid, a Vaginal Microbiota Metabolite, Elicits an Anti-inflammatory Response from Vaginal and Cervical Epithelial Cells

Long-term foscarnet therapy not associated with the development of foscarnet-resistant human immunodeficiency virus type 1 in an acquired immunodeficiency syndrome patient.

Maturation of the HIV reverse transcription complex: putting the jigsaw together

Mechanisms of inhibition of HIV replication by non-nucleoside reverse transcriptase inhibitors

Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules

Molecular dissection of an inhibitor targeting the HIV integrase dependent preintegration complex nuclear import

Mutations that abrogate human immunodeficiency virus type 1 reverse transcriptase dimerization affect maturation of the reverse transcriptase heterodimer

N348I in HIV-1 reverse transcriptase counteracts the synergy between zidovudine and nevirapine

N348I in HIV-1 reverse transcriptase decreases susceptibility to tenofovir and etravirine in combination with other resistance mutations

N348I in reverse transcriptase provides a genetic pathway for HIV-1 to select thymidine analogue mutations and mutations antagonistic to thymidine analogue mutations

N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance

No association between XMRV or related gammaretroviruses in Australian prostate cancer patients

Nonnucleoside Reverse Transcriptase Inhibitors Reduce HIV-1 Production from Latently Infected Resting CD4+ T Cells following Latency Reversal.

Nonnucleoside reverse transcriptase inhibitors are chemical enhancers of dimerization of the HIV type 1 reverse transcriptase

Oxazole-benzenesulfonamide derivatives inhibit HIV-1 reverse transcriptase interaction with cellular eEF1A and reduce viral replication

Phosphatidylethanolamine binding is a conserved feature of cyclotide-membrane interactions

Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-Pol

Relationship between enzyme activity and dimeric structure of recombinant HIV-1 reverse transcriptase

Reverse transcriptase mutations in sequential HIV-1 isolates in a patient with AIDS.

Role of RNase H Activity in NRTI/NNRTI Drug Resistance

Role of residues in the tryptophan repeat motif for HIV-1 reverse transcriptase dimerization

SPL7013 Gel (VivaGel®) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humans

Sensitive assessment of the virologic outcomes of stopping and restarting non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy

Silent mutations at codons 65 and 66 in reverse transcriptase alleviate indel formation and restore fitness in subtype B HIV-1 containing D67N and K70R drug resistance mutations

Structure activity relationship of dendrimer microbicides with dual action antiviral activity

Synergistic Inhibition of Human Immunodeficiency Virus Type 1 in vitro by Interferon Alpha and Coumermycin A1

Synergistic inhibition of human immunodefficiency virus type 1 in vitro by coumermycin A1 and human leukocyte interferon

Targeting Human Immunodeficiency Virus Type 1 Assembly, Maturation and Budding

The NRTIs lamivudine, stavudine and zidovudine have reduced HIV-1 inhibitory activity in astrocytes

The effect of NNRTIs on HIV reverse transcriptase dimerization.

The human immunodeficiency virus type 1 nonnucleoside reverse transcriptase inhibitor resistance mutation I132M confers hypersensitivity to nucleoside analogs

The implausible "in vivo" role of hydrogen peroxide as an antimicrobial factor produced by vaginal microbiota

The packaging and maturation of the HIV-1 Pol proteins

The role of lactic acid production by probiotic Lactobacillus species in vaginal health

The seventh (and last?) International Microbicides Conference: from discovery to delivery

Ubisol-Aqua: coenzyme Q10 prevents antiretroviral toxic neuropathy in an in vitro model

Vaginal Concentrations of Lactic Acid Potently Inactivate HIV-1 Compared to Short Chain Fatty Acids Present During Bacterial Vaginosis

Vaginal concentrations of lactic acid potently inactivate HIV

Virological significance, prevalence and genetic basis of hypersusceptibility to nonnucleoside reverse transcriptase inhibitors

A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats