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Lista de obras de Philipp F Lange

Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic peptide cleavage analyses.

artículo científico publicado en 2015

Annotating N termini for the human proteome project: N termini and Nα-acetylation status differentiate stable cleaved protein species from degradation remnants in the human erythrocyte proteome

artículo científico publicado en 2014

ClC-7 requires Ostm1 as a beta-subunit to support bone resorption and lysosomal function

scientific journal article

Ensembles of protein termini and specific proteolytic signatures as candidate biomarkers of disease.

artículo científico publicado en 2014

HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development

artículo científico publicado en 2017

Macrophage matrix metalloproteinase-12 dampens inflammation and neutrophil influx in arthritis

artículo científico publicado en 2014

Modification of BRCA1-associated breast cancer risk by HMMR overexpression

artículo científico publicado en 2022

Network analyses reveal pervasive functional regulation between proteases in the human protease web

artículo científico publicado en 2014

Novel matrix metalloproteinase inhibitor [18F]marimastat-aryltrifluoroborate as a probe for in vivo positron emission tomography imaging in cancer.

artículo científico publicado en 2010

Origins and clinical relevance of proteoforms in pediatric malignancies

artículo científico publicado en 2019

PDX models reflect the proteome landscape of pediatric acute lymphoblastic leukemia but divert in select pathways

artículo científico publicado en 2021

Pathogenic BRCA1 variants disrupt PLK1-regulation of mitotic spindle orientation

artículo científico publicado en 2022

Protein TAILS: when termini tell tales of proteolysis and function

artículo científico publicado en 2013

Proteome TopFIND 3.0 with TopFINDer and PathFINDer: database and analysis tools for the association of protein termini to pre- and post-translational events.

artículo científico publicado en 2014

Proteomic amino-termini profiling reveals targeting information for protein import into complex plastids

artículo científico publicado en 2013

Robust unsupervised deconvolution of linear motifs characterizes 68 protein modifications at proteome scale

artículo científico publicado en 2021

Sensitive Determination of Proteolytic Proteoforms in Limited Microscale Proteome Samples

scientific article published on 30 August 2019

TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors

artículo científico publicado en 2016

TopFIND 2.0--linking protein termini with proteolytic processing and modifications altering protein function

artículo científico publicado en 2011

Tumor Variant Identification That Accounts for the Unique Molecular Landscape of Pediatric Malignancies

artículo científico publicado en 2018