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Lista de obras de Antonio Scilimati

A chemoenzymatic scalable route to optically active (R)-1-(pyridin-3-yl)-2-aminoethanol, valuable moiety of beta3-adrenergic receptor agonists

artículo científico publicado en 2005

Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents

artículo científico publicado en 2008

Cyclooxygenase Inhibition Safety and Efficacy in Inflammation-Based Psychiatric Disorders

artículo científico publicado en 2020

Diarylheterocycle Core Ring Features Effect in Selective COX-1 Inhibition

artículo científico publicado en 2012

Effect of mofezolac-galactose distance in conjugates targeting cyclooxygenase (COX)-1 and CNS GLUT-1 carrier.

artículo científico publicado en 2017

General role of the amino and methylsulfamoyl groups in selective cyclooxygenase(COX)-1 inhibition by 1,4-diaryl-1,2,3-triazoles and validation of a predictive pharmacometric PLS model

scientific article published on 28 February 2015

Myogenic effect of SP-1f and SP-1h two novel β3-adrenoceptor (β3-AR) agonists in human colonic circular smooth muscle.

artículo científico publicado en 2013

Novel selective COX-1 inhibitors suppress neuroinflammatory mediators in LPS-stimulated N13 microglial cells

artículo científico publicado el 1 de octubre de 2011

Optically Active Mexiletine Analogues as Stereoselective Blockers of Voltage-Gated Na+Channels

Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na(+) channels

artículo científico publicado en 2003

Optimal requirements for high affinity and use-dependent block of skeletal muscle sodium channel by N-benzyl analogs of tocainide-like compounds

artículo científico publicado en 2003

PET radiotracer [¹⁸F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: preliminary investigation.

artículo científico publicado en 2014

Selective COX-1 inhibition as a target of theranostic novel diarylisoxazoles.

artículo científico publicado en 2014

Selective COX-1 inhibition: A therapeutic target to be reconsidered.

artículo científico publicado en 2010

Selective Cyclooxygenase-1 Inhibition by P6 and Gastrotoxicity: Preliminary Investigation

artículo científico publicado en 2015

Stereospecific synthesis and bio-activity of novel beta(3)-adrenoceptor agonists and inverse agonists.

artículo científico publicado en 2007

Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6).

artículo científico publicado en 2017

Synthesis of new 2,6-prolylxylidide analogues of tocainide as stereoselective blockers of voltage-gated Na(+) channels with increased potency and improved use-dependent activity.

artículo científico publicado en 2000

Synthesis, pharmacological characterization, and docking analysis of a novel family of diarylisoxazoles as highly selective cyclooxygenase-1 (COX-1) inhibitors

artículo científico publicado en 2013

The tertiary amine nitrogen atom of piperazine sulfonamides as a novel determinant of potent and selective beta3-adrenoceptor agonists.

artículo científico publicado en 2009

Upregulation of β 3 -Adrenergic Receptor mRNA in Human Colon Cancer: A Preliminary Study

artículo científico publicado en 2008

β3-Adrenoceptor Agonists and (Antagonists as) Inverse Agonists

artículo científico publicado en 2010

β3-Adrenoceptor ligand development history through patent review

artículo científico publicado el 17 de marzo de 2011