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Lista de obras de Scott Ayton

A comparison of ceruloplasmin to biological polyanions in promoting the oxidation of Fe(2+) under physiologically relevant conditions.

artículo científico publicado en 2014

A delicate balance: Iron metabolism and diseases of the brain.

artículo científico publicado en 2013

Amine oxidase activity of β-amyloid precursor protein modulates systemic and local catecholamine levels.

artículo científico publicado en 2012

Association of Cerebrospinal Fluid Ferritin Level With Preclinical Cognitive Decline in APOE-ε4 Carriers.

artículo científico publicado en 2016

Association of metals with the risk and clinical characteristics of Parkinson's disease

artículo científico publicado en 2018

Axonal dispatch of iron in neuronal signaling

artículo científico publicado en 2019

Biometals and their therapeutic implications in Alzheimer's disease.

artículo científico publicado en 2015

Brain Zinc Deficiency Exacerbates Cognitive Decline in the R6/1 Model of Huntington's Disease

artículo científico publicado en 2020

Brain iron is associated with accelerated cognitive decline in people with Alzheimer pathology

scientific article published on 18 February 2019

Cellular Senescence and Iron Dyshomeostasis in Alzheimer's Disease

scientific article published on 19 June 2019

Cerebral quantitative susceptibility mapping predicts amyloid-β-related cognitive decline

Cerebrospinal fluid ferritin levels predict brain hypometabolism in people with underlying β-amyloid pathology

artículo científico publicado en 2018

Ceruloplasmin and β-amyloid precursor protein confer neuroprotection in traumatic brain injury and lower neuronal iron.

artículo científico publicado en 2014

Clioquinol rescues Parkinsonism and dementia phenotypes of the tau knockout mouse

artículo científico publicado en 2015

CuII (atsm) inhibits ferroptosis: Implications for treatment of neurodegenerative disease

scientific article published on 14 January 2020

Decreasing iron neurotoxicity in pantothenate kinase-associated neurodegeneration

scientific article published on 01 July 2019

Elevated plasma ferritin in elderly individuals with high neocortical amyloid-β load.

artículo científico publicado en 2017

Enduring Elevations of Hippocampal Amyloid Precursor Protein and Iron Are Features of β-Amyloid Toxicity and Are Mediated by Tau

artículo científico publicado en 2015

Evidence of a Cardiovascular Function for Microtubule-Associated Protein Tau.

artículo científico publicado en 2017

Evidence that iron accelerates Alzheimer's pathology: a CSF biomarker study.

artículo científico publicado en 2017

Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE

artículo científico publicado en 2015

Ferroptosis and cell death mechanisms in Parkinson's disease.

artículo científico publicado en 2017

GSK-3 in Neurodegenerative Diseases.

artículo científico publicado en 2011

Increased Ndfip1 in the substantia nigra of Parkinsonian brains is associated with elevated iron levels

artículo científico publicado en 2014

Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson's disease

artículo científico publicado en 2014

Iron and Alzheimer's Disease: An Update on Emerging Mechanisms

artículo científico publicado en 2018

Lithium suppression of tau induces brain iron accumulation and neurodegeneration.

artículo científico

Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice

artículo científico publicado en 2018

Metallostasis in Alzheimer's disease.

artículo científico publicado en 2012

Mice overexpressing hepcidin suggest ferroportin does not play a major role in Mn homeostasis

artículo científico publicado en 2019

More evidence is needed. Iron, incident cognitive decline and dementia: a systematic review

article

Motor and cognitive deficits in aged tau knockout mice in two background strains.

artículo científico publicado en 2014

Nanoscale Imaging Reveals Big Role for Iron in Alzheimer's Disease

artículo científico publicado en 2017

Neoadjuvant neratinib promotes ferroptosis and inhibits brain metastasis in a novel syngeneic model of spontaneous HER2+ve breast cancer metastasis

artículo científico publicado en 2019

Nigral iron elevation is an invariable feature of Parkinson's disease and is a sufficient cause of neurodegeneration

artículo científico publicado en 2014

Overcoming the Blood-Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases

artículo científico publicado en 2018

PBT2 Reduces Toxicity in a C. elegans Model of polyQ Aggregation and Extends Lifespan, Reduces Striatal Atrophy and Improves Motor Performance in the R6/2 Mouse Model of Huntington's Disease

artículo científico publicado en 2012

Parkinson's disease iron deposition caused by nitric oxide-induced loss of β-amyloid precursor protein.

artículo científico publicado en 2015

S-sulfocysteine/NMDA receptor-dependent signaling underlies neurodegeneration in molybdenum cofactor deficiency.

artículo científico publicado en 2017

Selective ferroptosis vulnerability due to familial Alzheimer's disease presenilin mutations

Serotonergic lesions of the dorsal hippocampus differentially modulate locomotor hyperactivity induced by drugs of abuse in rats: implications for schizophrenia.

artículo científico publicado en 2009

Serotonergic markers in Parkinson's disease and levodopa-induced dyskinesias

artículo científico publicado en 2015

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export.

artículo científico publicado en 2012

Tau protein: relevance to Parkinson's disease

artículo científico publicado en 2010

Tau-mediated iron export prevents ferroptotic damage after ischemic stroke

artículo científico publicado en 2017

The Aβ-induced NFAT apoptotic pathway is also activated by GSK-3 inhibition: implications for Alzheimer therapeutics.

artículo científico publicado en 2012

The Complex Role of Apolipoprotein E in Alzheimer's Disease: an Overview and Update

artículo científico publicado en 2016

The Essential Elements of Alzheimer's Disease

scientific article published on 20 November 2020

The effect of dopamine on MPTP-induced rotarod disability.

artículo científico publicado en 2013

The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease

artículo científico publicado en 2012

The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson's disease

artículo científico publicado en 2017

Transferrin protects against Parkinsonian neurotoxicity and is deficient in Parkinson's substantia nigra

artículo científico publicado en 2016

Treating Alzheimer's disease by targeting iron

artículo científico publicado en 2019

Type-1 interferons contribute to the neuroinflammatory response and disease progression of the MPTP mouse model of Parkinson's disease.

artículo científico publicado en 2016

Zn-DTSM, A Zinc Ionophore with Therapeutic Potential for Acrodermatitis Enteropathica?

artículo científico publicado en 2019

α-Synuclein transgenic mice reveal compensatory increases in Parkinson's disease-associated proteins DJ-1 and parkin and have enhanced α-synuclein and PINK1 levels after rotenone treatment.

artículo científico publicado en 2010