Lista de obras - Robert O'Connor - Dominio Público Uruguay

A gene expression profile indicative of early stage HER2 targeted therapy response ⬇️

artículo científico publicado el 1 de julio de 2013

A novel panel of protein biomarkers for predicting response to thalidomide-based therapy in newly diagnosed multiple myeloma patients

artículo científico publicado en 2011

A phase I clinical and pharmacokinetic study of the multi-drug resistance protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancer.

artículo científico publicado en 2006

A review of mechanisms of circumvention and modulation of chemotherapeutic drug resistance.

artículo científico publicado en 2009

Artificial Neural Networks for Classification in Metabolomic Studies of Whole Cells Using 1H Nuclear Magnetic Resonance ⬇️

artículo científico publicado el 15 de septiembre de 2010

CYP1B1 expression is induced by docetaxel: effect on cell viability and drug resistance.

artículo científico publicado en 2008

Challenges of drug resistance in the management of pancreatic cancer ⬇️

artículo científico publicado el 1 de octubre de 2010

Characterisation and manipulation of docetaxel resistant prostate cancer cell lines

artículo científico publicado en 2011

Determination of serum and tissue levels of phenazines including clofazimine

artículo científico publicado en 1996

Development, validation and application of a sensitive LC-MS/MS method for the quantification of thalidomide in human serum, cells and cell culture medium.

artículo científico publicado en 2012

Drug metabolism-related genes as potential biomarkers: analysis of expression in normal and tumour breast tissue.

artículo científico publicado en 2007

Drug resistance in cancer - searching for mechanisms, markers and therapeutic agents

artículo científico publicado en 2007

Enhanced in vitro invasiveness and drug resistance with altered gene expression patterns in a human lung carcinoma cell line after pulse selection with anticancer drugs.

artículo científico publicado en 2004

Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs)

article

Gene expression changes as markers of early lapatinib response in a panel of breast cancer cell lines

artículo científico publicado en 2012

Increased anti-tumour efficacy of doxorubicin when combined with sulindac in a xenograft model of an MRP-1-positive human lung cancer.

artículo científico publicado en 2004

Metabolomic studies of human lung carcinoma cell lines using in vitro (1)H NMR of whole cells and cellular extracts.

artículo científico publicado en 2008

Methods for generation of monoclonal antibodies to the very small drug hapten, 5-benzimidazolecarboxylic acid.

artículo científico publicado en 2002

Modulation of P-gp expression by lapatinib.

artículo científico publicado en 2010

Overexpression of cytochrome P450 NADPH reductase sensitises MDA 231 breast carcinoma cells to 5-fluorouracil: possible mechanisms involved.

artículo científico publicado en 2007

Rapid and sensitive liquid chromatography-tandem mass spectrometry for the quantitation of epirubicin and identification of metabolites in biological samples

artículo científico publicado en 2006

Recent developments in drug resistance and apoptosis research.

artículo científico publicado en 1998

Simultaneous determination of anthracyclines and taxanes in human serum using online sample extraction coupled to high performance liquid chromatography with UV detection.

artículo científico publicado en 2010

Simultaneous determination of efavirenz, rifampicin and its metabolite desacetyl rifampicin levels in human plasma.

artículo científico publicado en 2011

Stable Aqueous Dispersions of Glycopeptide-Grafted Selectably Functionalized Magnetic Nanoparticles

artículo científico publicado en 2013

Structure-activity relationship of indomethacin analogues for MRP-1, COX-1 and COX-2 inhibition. identification of novel chemotherapeutic drug resistance modulators.

artículo científico publicado en 2002

The pharmacology of cancer resistance.

artículo científico publicado en 2007

The pharmacology, metabolism, and chemistry of clofazimine.

artículo científico publicado en 1995

The use of LC-MS to identify differentially expressed proteins in docetaxel-resistant prostate cancer cell lines

artículo científico publicado en 2012

Tyrosine kinase inhibitors potentiate the cytotoxicity of MDR-substrate anticancer agents independent of growth factor receptor status in lung cancer cell lines.

artículo científico publicado en 2009

Use of proton NMR spectroscopy in the toxicological evaluation of new anti-mycobacterial agents

scientific article published on 01 May 1995

Lista de obras de Robert O'Connor

A gene expression profile indicative of early stage HER2 targeted therapy response ⬇️

A novel panel of protein biomarkers for predicting response to thalidomide-based therapy in newly diagnosed multiple myeloma patients

A phase I clinical and pharmacokinetic study of the multi-drug resistance protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancer.

A review of mechanisms of circumvention and modulation of chemotherapeutic drug resistance.

Artificial Neural Networks for Classification in Metabolomic Studies of Whole Cells Using 1H Nuclear Magnetic Resonance ⬇️

CYP1B1 expression is induced by docetaxel: effect on cell viability and drug resistance.

Challenges of drug resistance in the management of pancreatic cancer ⬇️

Characterisation and manipulation of docetaxel resistant prostate cancer cell lines

Determination of serum and tissue levels of phenazines including clofazimine

Development, validation and application of a sensitive LC-MS/MS method for the quantification of thalidomide in human serum, cells and cell culture medium.

Drug metabolism-related genes as potential biomarkers: analysis of expression in normal and tumour breast tissue.

Drug resistance in cancer - searching for mechanisms, markers and therapeutic agents

Enhanced in vitro invasiveness and drug resistance with altered gene expression patterns in a human lung carcinoma cell line after pulse selection with anticancer drugs.

Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs)

Gene expression changes as markers of early lapatinib response in a panel of breast cancer cell lines

Increased anti-tumour efficacy of doxorubicin when combined with sulindac in a xenograft model of an MRP-1-positive human lung cancer.

Metabolomic studies of human lung carcinoma cell lines using in vitro (1)H NMR of whole cells and cellular extracts.

Methods for generation of monoclonal antibodies to the very small drug hapten, 5-benzimidazolecarboxylic acid.

Modulation of P-gp expression by lapatinib.

Overexpression of cytochrome P450 NADPH reductase sensitises MDA 231 breast carcinoma cells to 5-fluorouracil: possible mechanisms involved.

Rapid and sensitive liquid chromatography-tandem mass spectrometry for the quantitation of epirubicin and identification of metabolites in biological samples

Recent developments in drug resistance and apoptosis research.

Simultaneous determination of anthracyclines and taxanes in human serum using online sample extraction coupled to high performance liquid chromatography with UV detection.

Simultaneous determination of efavirenz, rifampicin and its metabolite desacetyl rifampicin levels in human plasma.

Stable Aqueous Dispersions of Glycopeptide-Grafted Selectably Functionalized Magnetic Nanoparticles

Structure-activity relationship of indomethacin analogues for MRP-1, COX-1 and COX-2 inhibition. identification of novel chemotherapeutic drug resistance modulators.

The pharmacology of cancer resistance.

The pharmacology, metabolism, and chemistry of clofazimine.

The use of LC-MS to identify differentially expressed proteins in docetaxel-resistant prostate cancer cell lines

Tyrosine kinase inhibitors potentiate the cytotoxicity of MDR-substrate anticancer agents independent of growth factor receptor status in lung cancer cell lines.

Use of proton NMR spectroscopy in the toxicological evaluation of new anti-mycobacterial agents