Lista de obras - Jean Cavarelli - Dominio Público Uruguay

A high resolution diffracting crystal form of the complex between yeast tRNAAsp and aspartyl-tRNA synthetase

artículo científico publicado en 1988

Active site mapping of yeast aspartyl-tRNA synthetase by in vivo selection of enzyme mutations lethal for cell growth.

artículo científico publicado en 1999

Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1.

artículo científico publicado en 2011

Biochemical and NMR mapping of the interface between CREB-binding protein and ligand binding domains of nuclear receptor: beyond the LXXLL motif

artículo científico publicado en 2004

Cloning, expression, purification and preliminary X-ray crystallographic analysis of mouse protein arginine methyltransferase 7.

artículo científico publicado en 2013

Cloning, purification and crystallization of a Walker-type Pyrococcus abyssi ATPase family member.

artículo científico publicado en 2005

Conformational flexibility of tRNA: structural changes in yeast tRNA(Asp) upon binding to aspartyl-tRNA synthetase.

artículo científico publicado en 1996

Crystal structure of the V-region of Streptococcus mutans antigen I/II at 2.4 A resolution suggests a sugar preformed binding site

artículo científico publicado en 2002

Crystal structure, biochemical and genetic characterization of yeast and E. cuniculi TAF(II)5 N-terminal domain: implications for TFIID assembly

artículo científico publicado en 2007

Crystallization and preliminary X-ray crystallographic analysis of yeast arginyl-tRNA synthetase-yeast tRNAArg complexes

artículo científico publicado en 2000

Crystallization and preliminary X-ray crystallographic study of the wild type and two mutants of the CP1 hydrolytic domain from Aquifex aeolicus leucyl-tRNA synthetase.

artículo científico publicado en 2005

Crystallogenesis studies on yeast aspartyl-tRNA synthetase: use of phase diagram to improve crystal quality

artículo científico publicado en 1999

Electrostatic potential in aminoacylation by aspartyl-tRNAs synthetase.

artículo científico publicado en 1995

Evidence for assembly-dependent folding of protein and RNA in an icosahedral virus

artículo científico publicado en 2003

Expression, purification, and characterization of a new heterotetramer structure of leucyl-tRNA synthetase from Aquifex aeolicus in Escherichia coli.

artículo científico publicado en 2005

Expression, purification, crystallization and preliminary crystallographic study of isolated modules of the mouse coactivator-associated arginine methyltransferase 1.

artículo científico publicado en 2007

Functional insights from high resolution structures of mouse protein arginine methyltransferase 6

artículo científico publicado en 2015

Functional insights from structures of coactivator-associated arginine methyltransferase 1 domains

artículo científico publicado en 2007

Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors

artículo científico publicado en 2018

Identification of small-molecule enhancers of arginine methylation catalyzed by coactivator-associated arginine methyltransferase 1.

artículo científico publicado en 2012

Insight into the remarkable affinity and selectivity of the aminobenzosuberone scaffold for the M1 aminopeptidases family based on structure analysis.

artículo científico publicado en 2017

L-Arginine recognition by yeast arginyl-tRNA synthetase ⬇️

artículo científico publicado el 15 de septiembre de 1998

Molecular basis for the antiparasitic activity of a mercaptoacetamide derivative that inhibits histone deacetylase 8 (HDAC8) from the human pathogen schistosoma mansoni

artículo científico publicado en 2014

Mutation and evolution of the magnesium-binding site of a class II aminoacyl-tRNA synthetase.

artículo científico publicado en 2004

Noncanonical Tandem SH2 Enables Interaction of Elongation Factor Spt6 with RNA Polymerase II

artículo científico publicado en 2010

On the Structure and Function of the Phytoene Desaturase CRTI from Pantoea ananatis, a Membrane-Peripheral and FAD-Dependent Oxidase/Isomerase

artículo científico publicado en 2012

SECIS-binding protein 2 interacts with the SMN complex and the methylosome for selenoprotein mRNP assembly and translation

artículo científico publicado en 2017

Structural basis for group A trichothiodystrophy

artículo científico publicado en 2008

Structural basis for hijacking of cellular LxxLL motifs by papillomavirus E6 oncoproteins

artículo científico publicado en 2013

Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni

artículo científico publicado en 2013

Structural insight into arginine methylation by the mouse protein arginine methyltransferase 7: a zinc finger freezes the mimic of the dimeric state into a single active site

artículo científico publicado en 2014

Structural insights into transcription complexes.

artículo científico publicado en 2011

Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors

artículo científico publicado en 2016

Structure determination of the minimal complex between Tfb5 and Tfb2, two subunits of the yeast transcription/DNA-repair factor TFIIH: a retrospective study.

artículo científico publicado en 2010

Structure of the Elongator cofactor complex Kti11/Kti13 provides insight into the role of Kti13 in Elongator-dependent tRNA modification

artículo científico publicado en 2015

Structures of RNA-binding proteins

artículo científico publicado el 1 de agosto de 1997

TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL

artículo científico publicado en 2016

The 2.8 A structure of a T = 4 animal virus and its implications for membrane translocation of RNA.

artículo científico publicado en 1996

The class II aminoacyl-tRNA synthetases and their active site: evolutionary conservation of an ATP binding site

scientific article published on 01 May 1995

The free yeast aspartyl-tRNA synthetase differs from the tRNA(Asp)-complexed enzyme by structural changes in the catalytic site, hinge region, and anticodon-binding domain

artículo científico publicado en 2000

The structure of Staphylococcus aureus epidermolytic toxin A, an atypic serine protease, at 1.7 A resolution

artículo científico publicado en 1997

The structure of an Iws1/Spt6 complex reveals an interaction domain conserved in TFIIS, Elongin A and Med26

artículo científico publicado en 2010

Transition state mimics are valuable mechanistic probes for structural studies with the arginine methyltransferase CARM1.

artículo científico publicado en 2017

Translationally controlled tumor protein is a target of tumor reversion

artículo científico publicado en 2004

Yeast aspartyl-tRNA synthetase: a structural view of the aminoacylation reaction

artículo científico publicado en 1993

Yeast tRNA(Asp)-aspartyl-tRNA synthetase complex: low resolution crystal structure

artículo científico publicado en 1987

Yeast tRNAAsp recognition by its cognate class II aminoacyl-tRNA synthetase

artículo científico publicado en 1993

tRNA aminoacylation by arginyl-tRNA synthetase: induced conformations during substrates binding

artículo científico publicado en 2000

Lista de obras de Jean Cavarelli

A high resolution diffracting crystal form of the complex between yeast tRNAAsp and aspartyl-tRNA synthetase

Active site mapping of yeast aspartyl-tRNA synthetase by in vivo selection of enzyme mutations lethal for cell growth.

Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1.

Biochemical and NMR mapping of the interface between CREB-binding protein and ligand binding domains of nuclear receptor: beyond the LXXLL motif

Cloning, expression, purification and preliminary X-ray crystallographic analysis of mouse protein arginine methyltransferase 7.

Cloning, purification and crystallization of a Walker-type Pyrococcus abyssi ATPase family member.

Conformational flexibility of tRNA: structural changes in yeast tRNA(Asp) upon binding to aspartyl-tRNA synthetase.

Crystal structure of the V-region of Streptococcus mutans antigen I/II at 2.4 A resolution suggests a sugar preformed binding site

Crystal structure, biochemical and genetic characterization of yeast and E. cuniculi TAF(II)5 N-terminal domain: implications for TFIID assembly

Crystallization and preliminary X-ray crystallographic analysis of yeast arginyl-tRNA synthetase-yeast tRNAArg complexes

Crystallization and preliminary X-ray crystallographic study of the wild type and two mutants of the CP1 hydrolytic domain from Aquifex aeolicus leucyl-tRNA synthetase.

Crystallogenesis studies on yeast aspartyl-tRNA synthetase: use of phase diagram to improve crystal quality

Electrostatic potential in aminoacylation by aspartyl-tRNAs synthetase.

Evidence for assembly-dependent folding of protein and RNA in an icosahedral virus

Expression, purification, and characterization of a new heterotetramer structure of leucyl-tRNA synthetase from Aquifex aeolicus in Escherichia coli.

Expression, purification, crystallization and preliminary crystallographic study of isolated modules of the mouse coactivator-associated arginine methyltransferase 1.

Functional insights from high resolution structures of mouse protein arginine methyltransferase 6

Functional insights from structures of coactivator-associated arginine methyltransferase 1 domains

Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors

Identification of small-molecule enhancers of arginine methylation catalyzed by coactivator-associated arginine methyltransferase 1.

Insight into the remarkable affinity and selectivity of the aminobenzosuberone scaffold for the M1 aminopeptidases family based on structure analysis.

L-Arginine recognition by yeast arginyl-tRNA synthetase ⬇️

Molecular basis for the antiparasitic activity of a mercaptoacetamide derivative that inhibits histone deacetylase 8 (HDAC8) from the human pathogen schistosoma mansoni

Mutation and evolution of the magnesium-binding site of a class II aminoacyl-tRNA synthetase.

Noncanonical Tandem SH2 Enables Interaction of Elongation Factor Spt6 with RNA Polymerase II

On the Structure and Function of the Phytoene Desaturase CRTI from Pantoea ananatis, a Membrane-Peripheral and FAD-Dependent Oxidase/Isomerase

SECIS-binding protein 2 interacts with the SMN complex and the methylosome for selenoprotein mRNP assembly and translation

Structural basis for group A trichothiodystrophy

Structural basis for hijacking of cellular LxxLL motifs by papillomavirus E6 oncoproteins

Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni

Structural insight into arginine methylation by the mouse protein arginine methyltransferase 7: a zinc finger freezes the mimic of the dimeric state into a single active site

Structural insights into transcription complexes.

Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors

Structure determination of the minimal complex between Tfb5 and Tfb2, two subunits of the yeast transcription/DNA-repair factor TFIIH: a retrospective study.

Structure of the Elongator cofactor complex Kti11/Kti13 provides insight into the role of Kti13 in Elongator-dependent tRNA modification

Structures of RNA-binding proteins

TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL

The 2.8 A structure of a T = 4 animal virus and its implications for membrane translocation of RNA.

The class II aminoacyl-tRNA synthetases and their active site: evolutionary conservation of an ATP binding site

The free yeast aspartyl-tRNA synthetase differs from the tRNA(Asp)-complexed enzyme by structural changes in the catalytic site, hinge region, and anticodon-binding domain

The structure of Staphylococcus aureus epidermolytic toxin A, an atypic serine protease, at 1.7 A resolution

The structure of an Iws1/Spt6 complex reveals an interaction domain conserved in TFIIS, Elongin A and Med26

Transition state mimics are valuable mechanistic probes for structural studies with the arginine methyltransferase CARM1.

Translationally controlled tumor protein is a target of tumor reversion

Yeast aspartyl-tRNA synthetase: a structural view of the aminoacylation reaction

Yeast tRNA(Asp)-aspartyl-tRNA synthetase complex: low resolution crystal structure

Yeast tRNAAsp recognition by its cognate class II aminoacyl-tRNA synthetase

tRNA aminoacylation by arginyl-tRNA synthetase: induced conformations during substrates binding