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Lista de obras de Silvio Aime

1,2-hydroxypyridonate/terephthalamide complexes of gadolinium(III): synthesis, stability, relaxivity, and water exchange properties

artículo científico publicado en 2009

1,2-hydroxypyridonates as contrast agents for magnetic resonance imaging: TREN-1,2-HOPO.

artículo científico publicado en 2007

15N Magnetic Resonance Hyperpolarization via the Reaction of Parahydrogen with 15N-Propargylcholine ⬇️

artículo científico publicado el 26 de junio de 2012

15N‐Permethylated amino acids as efficient probes for MRI‐DNP applications ⬇️

artículo científico publicado el 1 de septiembre de 2013

1H and17O relaxometric investigations of the binding of Mn(II) ion to human serum albumin

6-Carboxamido-5,4-Hydroxypyrimidinones: A New Class of Heterocyclic Ligands and Their Evaluation as Gadolinium Chelating Agents ⬇️

artículo científico publicado el 17 de diciembre de 2001

A R2/R1 ratiometric procedure for a concentration-independent, pH-responsive, Gd(III)-based MRI agent

artículo científico publicado en 2006

A R2p /R1p ratiometric procedure to assess matrix metalloproteinase-2 activity by magnetic resonance imaging.

artículo científico publicado en 2013

A carborane-derivative "click" reaction under heterogeneous conditions for the synthesis of a promising lipophilic MRI/GdBNCT agent.

artículo científico publicado en 2012

A copper-activated magnetic resonance imaging contrast agent with improved turn-on relaxivity response and anion compatibility

artículo científico publicado en 2009

A general MRI-CEST ratiometric approach for pH imaging: demonstration of in vivo pH mapping with iobitridol

artículo científico publicado en 2014

A highly stable gadolinium complex with a fast, associative mechanism of water exchange.

artículo científico publicado en 2003

A multinuclear NMR relaxometry study of ternary adducts formed between heptadentate Gd(III) chelates and L-lactate

artículo científico publicado en 2005

A new ytterbium chelate as contrast agent in chemical shift imaging and temperature sensitive probe for MR spectroscopy

artículo científico publicado en 1996

A novel 19F-NMR method for the investigation of the antioxidant capacity of biomolecules and biofluids

artículo científico publicado en 1999

A novel method of cellular labeling: anchoring mr-imaging reporter particles on the outer cell surface.

artículo científico publicado en 2008

A novel non-facial mode of azulene cluster co-ordination. Crystal and molecular structure of the dicarbenoid Os3(μ-H)2(CO)9(μ3-η1∶η1∶η1-C10H6)

A paramagnetic MRI-CEST agent responsive to lactate concentration

artículo científico publicado en 2002

A paramagnetic probe to localize residues next to carboxylates on protein surfaces

artículo científico publicado en 2002

A quantitative relaxometric version of the ELISA test for the measurement of cell surface biomarkers

artículo científico publicado en 2014

A relaxometric method for the assessment of intestinal permeability based on the oral administration of gadolinium-based MRI contrast agents

artículo científico publicado en 2016

A theranostic approach based on the use of a dual boron/Gd agent to improve the efficacy of Boron Neutron Capture Therapy in the lung cancer treatment.

artículo científico publicado en 2015

A vaccine targeting angiomotin induces an antibody response which alters tumor vessel permeability and hampers the growth of established tumors ⬇️

artículo científico publicado el 17 de marzo de 2012

AAZTA: An Ideal Chelating Agent for the Development of 44 Sc PET Imaging Agents.

artículo científico publicado en 2017

Advances in Metal-Based Probes for MR Molecular Imaging Applications ⬇️

artículo científico publicado el 1 de enero de 2010

Advances in bio-imaging: A survey from WWMR 2010 ⬇️

artículo científico publicado el 3 de marzo de 2011

An MRI Method To Map Tumor Hypoxia Using Red Blood Cells Loaded with a pO2-Responsive Gd-Agent

artículo científico publicado en 2015

An iron-based T1 contrast agent made of iron-phosphate complexes: in vitro and in vivo studies.

artículo científico publicado en 2007

Asparagine in plums detected by CEST-MRI.

artículo científico publicado en 2014

Assessment of iron absorption in mice by ICP-MS measurements of 57Fe levels

artículo científico publicado en 2011

Azide, cyanide, fluoride, imidazole and pyridine binding to ferric and ferrous native horse heart cytochrome c and to its carboxymethylated derivative: a comparative study

artículo científico publicado en 1996

B25716/1: a novel albumin-binding Gd-AAZTA MRI contrast agent with improved properties in tumor imaging

artículo científico publicado en 2014

Biodistribution of gadolinium-based contrast agents, including gadolinium deposition

artículo científico publicado en 2009

Blast from the past: the aluminum's ghost on the lanthanum salts.

artículo científico publicado en 2005

Block copolymer vesicles containing paramagnetic lanthanide complexes: a novel class of T1- and CEST MRI contrast agents

Boronated compounds for imaging guided BNCT applications.

artículo científico

CEST and PARACEST Agents for Molecular Imaging

Carbon coated microshells containing nanosized Gd(iii) oxidic phases for multiple bio-medical applications

scientific article published on 08 October 2008

Cardio-chemical exchange saturation transfer magnetic resonance imaging reveals molecular signatures of endogenous fibrosis and exogenous contrast media

artículo científico publicado en 2014

Catalytic effects of apoferritin interior surface residues on water proton exchange in lanthanide complexes.

artículo científico publicado en 2006

Challenges for molecular magnetic resonance imaging

artículo científico publicado en 2010

Chapter 10 - Lanthanide-loaded paramagnetic liposomes as switchable magnetically oriented nanovesicles

artículo científico publicado en 2009

Characterization of human hair melanin and its degradation products by means of magnetic resonance techniques

artículo científico publicado en 2008

Chemical Shift and Relaxation Reagents in NMR*

Chemical exchange saturation transfer (CEST): an efficient tool for detecting molecular information on proteins' behaviour

artículo científico publicado en 2014

Chemistry of molecular imaging

artículo científico publicado en 2009

Cluster analysis of quantitative parametric maps from DCE-MRI: application in evaluating heterogeneity of tumor response to antiangiogenic treatment.

artículo científico publicado en 2015

Combined delivery and magnetic resonance imaging of neural cell adhesion molecule-targeted doxorubicin-containing liposomes in experimentally induced Kaposi's sarcoma

scientific article published on 09 March 2010

Combined high resolution NMR and 1H and 17O relaxometric study sheds light on the solution structure and dynamics of the lanthanide(III) complexes of HPDO3A.

artículo científico publicado en 2013

Combined inhibition of PI3Kβ and PI3Kγ reduces fat mass by enhancing α-MSH-dependent sympathetic drive

artículo científico publicado en 2014

Complete on/off responsive ParaCEST MRI contrast agents for copper and zinc

artículo científico publicado en 2018

Contrast agents and mechanisms

artículo científico publicado en 2011

Contrast agents for magnetic resonance angiographic applications: 1H and 17O NMR relaxometric investigations on two gadolinium(III) DTPA-like chelates endowed with high binding affinity to human serum albumin.

artículo científico publicado en 1999

Controlled mixing of lanthanide(III) ions in coacervate core micelles

artículo científico publicado en 2013

Copper-responsive magnetic resonance imaging contrast agents

artículo científico publicado en 2009

Correlation of Water Exchange Rate with Isomeric Composition in Diastereoisomeric Gadolinium Complexes of Tetra(carboxyethyl)dota and Related Macrocyclic Ligands

article

Curcumin/Gd loaded apoferritin: a novel "theranostic" agent to prevent hepatocellular damage in toxic induced acute hepatitis.

artículo científico publicado en 2013

Current concepts on hyperpolarized molecules in MRI.

artículo científico publicado en 2009

Dendrimeric Gd(III) complex of a monophosphinated DOTA analogue: optimizing relaxivity by reducing internal motion.

artículo científico publicado en 2005

Dependence of the relaxivity and luminescence of gadolinium and europium amino-acid complexes on hydrogencarbonate and pH

scholarly article by Silvio Aime et al published 1999 in Chemical Communications

Design and Synthesis of a γ(1)β(8)-Cyclodextrin Oligomer: A New Platform with Potential Application as a Dendrimeric Multicarrier

artículo científico publicado en 2013

Design and testing of paramagnetic liposome-based CEST agents for MRI visualization of payload release on pH-induced and ultrasound stimulation

artículo científico publicado en 2013

Designing Novel Contrast Agents for Magnetic Resonance Imaging. Synthesis and Relaxometric Characterization of three Gadolinium(III) Complexes Based on Functionalized Pyridine-Containing Macrocyclic Ligands

Determination of ferric heme-human serum albumin by 1H NMR relaxometry.

artículo científico publicado en 2003

Determination of water permeability of paramagnetic liposomes of interest in MRI field

artículo científico publicado en 2008

Development and validation of a smoothing-splines-based correction method for improving the analysis of CEST-MR images.

artículo científico publicado en 2008

Differences in Molecular Structure Markedly Affect GBCA Elimination Behavior

scientific article published on 26 February 2019

Diolein Based Nanostructures as Targeted Theranostics.

artículo científico publicado en 2016

Dissociation kinetics of open-chain and macrocyclic gadolinium(III)-aminopolycarboxylate complexes related to magnetic resonance imaging: catalytic effect of endogenous ligands

scientific article published on 08 November 2012

Dual MRI-SPECT agent for pH-mapping

artículo científico publicado en 2010

Dual-modality gene reporter for in vivo imaging

artículo científico publicado en 2013

EPR investigations of the iron domain in neuromelanin.

artículo científico publicado en 1997

Effect of a mesitylene-based ligand cap on the relaxometric properties of Gd(III) hydroxypyridonate MRI contrast agents.

artículo científico publicado en 2009

Effect of low and zero magnetic field on the hyperpolarization lifetime in parahydrogenated perdeuterated molecules.

artículo científico publicado en 2009

Effect of the intracellular localization of a Gd-based imaging probe on the relaxation enhancement of water protons

artículo científico publicado en 2006

Effects of Magnetic Field Cycle on the Polarization Transfer from Parahydrogen to Heteronuclei through Long-Range J-Couplings

artículo científico publicado en 2015

Efficient cellular labeling by CD44 receptor-mediated uptake of cationic liposomes functionalized with hyaluronic acid and loaded with MRI contrast agents.

artículo científico publicado en 2008

Efficient relaxivity enhancement in dendritic gadolinium complexes: effective motional coupling in medium molecular weight conjugates

artículo científico publicado en 2004

Encoding the frequency dependence in MRI contrast media: the emerging class of CEST agents

artículo científico publicado en 2010

Evaluation of 111In-labeled EPep and FibPep as tracers for fibrin SPECT imaging.

artículo científico publicado en 2013

Evaluation of the dose enhancement of combined10B +157Gd neutron capture therapy (NCT)

artículo científico publicado en 2015

Evidence for in vivo macrophage mediated tumor uptake of paramagnetic/fluorescent liposomes.

artículo científico publicado en 2009

Evidence for the Role of Intracellular Water Lifetime as a Tumour Biomarker Obtained by In Vivo Field-Cycling Relaxometry

artículo científico publicado en 2018

Extent of hydration of octadentate lanthanide complexes incorporating phosphinate donors: solution relaxometry and luminescence studies

Fe(III)-templated Gd(III) self-assemblies-a new route toward macromolecular MRI contrast agents

artículo científico publicado en 2006

First ex-vivo MRI co-localization of two LIPOCEST agents

artículo científico publicado en 2008

Frequency-encoded MRI-CEST agents based on paramagnetic liposomes/RBC aggregates.

artículo científico publicado en 2014

From spherical to osmotically shrunken paramagnetic liposomes: an improved generation of LIPOCEST MRI agents with highly shifted water protons

artículo científico publicado en 2007

Functional imaging of the angiogenic switch in a transgenic mouse model of human breast cancer by dynamic contrast enhanced magnetic resonance imaging.

artículo científico publicado en 2016

Gadolinium(III) Complexes of dota-DerivedN-Sulfonylacetamides (H4(dota-NHSO2R)=10-{2-[(R)sulfonylamino]-2-oxoethyl}-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic Acid): A New Class of Relaxation Agents for Magnetic Resonance Imaging Applications

Gadolinium-binding cyclic hexapeptoids: synthesis and relaxometric properties.

artículo científico publicado en 2013

Gadolinium-doped LipoCEST agents: a potential novel class of dual 1H-MRI probes

artículo científico publicado en 2011

Gd loading by hypotonic swelling: an efficient and safe route for cellular labeling

artículo científico publicado en 2013

Gd(DOTP)5-outer-sphere relaxation enhancement promoted by nitrogen bases.

artículo científico publicado en 1993

Gd(III)-BASED CONTRAST AGENTS FOR MRI

Gd-AAZTA-MADEC, an improved blood pool agent for DCE-MRI studies on mice on 1 T scanners.

artículo científico publicado en 2015

Gd-Loaded Liposomes asT1, Susceptibility, and CEST Agents, All in One

artículo científico publicado en 2007

Gd-enhanced MR images of substrates other than water

artículo científico publicado en 2006

Gd-loaded-RBCs for the assessment of tumor vascular volume by contrast-enhanced-MRI.

artículo científico publicado en 2015

Glycoconjugates of gadolinium complexes for MRI applications

artículo científico publicado en 2006

HR-MAS of cells: A "cellular water shift" due to water-protein interactions?

artículo científico publicado en 2005

Hetero-tripodal hydroxypyridonate gadolinium complexes: syntheses, relaxometric properties, water exchange dynamics, and human serum albumin binding.

artículo científico publicado en 2004

High kinetic inertness of a bis-hydrated Gd-complex with a constrained AAZTA-like ligand.

artículo científico publicado en 2016

High relaxivity gadolinium hydroxypyridonate-viral capsid conjugates: nanosized MRI contrast agents.

artículo científico publicado en 2008

High relaxivity supramolecular adducts between human-liver fatty-acid-binding protein and amphiphilic Gd(III) complexes: structural basis for the design of intracellular targeting MRI probes

artículo científico publicado en 2012

High-relaxivity gadolinium-modified high-density lipoproteins as magnetic resonance imaging contrast agents

artículo científico publicado en 2009

High-relaxivity magnetic resonance imaging (MRI) contrast agent based on supramolecular assembly between a gadolinium chelate, a modified dextran, and poly-beta-cyclodextrin.

artículo científico publicado en 2008

High-resolution NMR and relaxometric studies of Ln(III) complexes of relevance to MRI

Highly sensitive MRI chemical exchange saturation transfer agents using liposomes

artículo científico publicado en 2005

Highly shifted LIPOCEST agents based on the encapsulation of neutral polynuclear paramagnetic shift reagents

artículo científico publicado en 2007

Highly shifted proton MR imaging: cell tracking by using direct detection of paramagnetic compounds

artículo científico publicado en 2014

Highly soluble tris-hydroxypyridonate Gd(III) complexes with increased hydration number, fast water exchange, slow electronic relaxation, and high relaxivity

artículo científico publicado en 2007

How to design 13C para-hydrogen-induced polarization experiments for MRI applications

artículo científico publicado en 2010

Hyperpolarized (13) C-labelled anhydrides as DNP precursors of metabolic MRI agents

artículo científico publicado en 2012

Hyperpolarized (13)C-pyruvate magnetic resonance imaging in cancer diagnostics.

artículo científico publicado en 2012

Image guided therapy: the advent of theranostic agents

artículo científico publicado en 2012

Imaging probes—Introduction

artículo científico publicado en 2011

Imaging the pH evolution of an acute kidney injury model by means of iopamidol, a MRI-CEST pH-responsive contrast agent

artículo científico publicado en 2012

Improved paramagnetic liposomes for MRI visualization of pH triggered release

artículo científico publicado en 2011

Improved route for the visualization of stem cells labeled with a Gd-/Eu-chelate as dual (MRI and fluorescence) agent

artículo científico publicado en 2004

Improved syntheses of bis(beta-cyclodextrin) derivatives, new carriers for gadolinium complexes

artículo científico publicado en 2006

In Vitro and In Vivo Assessment of Nonionic Iodinated Radiographic Molecules as Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Tumor Perfusion Agents

artículo científico publicado en 2015

In Vivo Labeling of B16 Melanoma Tumor Xenograft with a Thiol-Reactive Gadolinium Based MRI Contrast Agent ⬇️

artículo científico publicado el 5 de agosto de 2011

In Vivo MR Imaging of Fibrin in a Neuroblastoma Tumor Model by Means of a Targeting Gd-Containing Peptide

artículo científico publicado en 2015

In vivo MRI multicontrast kinetic analysis of the uptake and intracellular trafficking of paramagnetically labeled liposomes

artículo científico publicado en 2010

In vivo MRI visualization of different cell populations labeled with PARACEST agents.

artículo científico publicado en 2012

In vivo MRI visualization of release from liposomes triggered by local application of pulsed low-intensity non-focused ultrasound

artículo científico publicado en 2014

In vivo maps of extracellular pH in murine melanoma by CEST-MRI.

artículo científico publicado en 2013

Innovative magnetic resonance imaging diagnostic agents based on paramagnetic Gd(III) complexes

scientific article published on 01 January 2002

Insights into the use of paramagnetic Gd(III) complexes in MR-molecular imaging investigations.

artículo científico publicado en 2002

In Vivo Magnetic Resonance Imaging Detection of Paramagnetic Liposomes Loaded with Amphiphilic Gadolinium(III) Complexes: Impact of Molecular Structure on Relaxivity and Excretion Efficiency

scientific article published on 03 June 2013

Iopamidol: Exploring the potential use of a well-established x-ray contrast agent for MRI.

artículo científico publicado en 2005

Lack of Plasma Protein Hemopexin Results in Increased Duodenal Iron Uptake

artículo científico publicado en 2013

Lanthanide(III) complexes of tris(amide) PCTA derivatives as potential bimodal magnetic resonance and optical imaging agents

artículo científico publicado en 2009

Lanthanide-Loaded Paramagnetic Liposomes as Switchable Magnetically Oriented Nanovesicles

artículo científico publicado en 2008

Lanthanide-loaded erythrocytes as highly sensitive chemical exchange saturation transfer MRI contrast agents.

artículo científico publicado en 2013

Ln(III)-DOTAMGly complexes: a versatile series to assess the determinants of the efficacy of paramagnetic chemical exchange saturation transfer agents for magnetic resonance imaging applications

artículo científico publicado en 2004

MEMRI and tumors: a method for the evaluation of the contribution of Mn(II) ions in the extracellular compartment.

artículo científico publicado en 2015

MRI CEST at 1T with large µeff Ln(3+) complexes T m(3+)-HPDO3A: An efficient MRI pH reporter

artículo científico publicado en 2015

MRI Visualization of Melanoma Cells by Targeting Overexpressed Sialic Acid with a GdIII-dota-en-pba Imaging Reporter

scientific article published on 06 December 2012

MRI evaluation of the antitumor activity of paramagnetic liposomes loaded with prednisolone phosphate

artículo científico publicado en 2011

MRI nanoprobes based on chemical exchange saturation transfer: Ln(III) chelates anchored on the surface of mesoporous silica nanoparticles

artículo científico publicado en 2014

MRI of cells and mice at 1 and 7 Tesla with Gd-targeting agents: when the low field is better!

artículo científico publicado en 2011

MRI tracking of macrophages labeled with glucan particles entrapping a water insoluble paramagnetic Gd-based agent

artículo científico publicado en 2013

MRI‐Guided Neutron Capture Therapy by Use of a Dual Gadolinium/Boron Agent Targeted at Tumour Cells through Upregulated Low‐Density Lipoprotein Transporters ⬇️

artículo científico publicado el 10 de junio de 2011

Macrocyclic paramagnetic agents for MRI: Determinants of relaxivity and strategies for their improvement

artículo científico publicado en 2016

Magnetic Resonance Visualization of Tumor Angiogenesis by Targeting Neural Cell Adhesion Molecules with the Highly Sensitive Gadolinium-Loaded Apoferritin Probe

artículo científico publicado en 2006

Magnetic resonance imaging detection of tumor cells by targeting low-density lipoprotein receptors with Gd-loaded low-density lipoprotein particles

artículo científico publicado en 2007

Magnetic resonance imaging of gadolinium-labeled pancreatic islets for experimental transplantation

scientific article published on 01 February 2007

Magnetic resonance imaging of the gastrointestinal tract: investigation of baby milk as a low cost contrast medium

artículo científico publicado el 1 de septiembre de 1992

Magnetic resonance imaging of tumor cells by targeting the amino acid transport system.

artículo científico publicado en 2006

Magnetic resonance imaging visualization of targeted cells by the internalization of supramolecular adducts formed between avidin and biotinylated Gd3+ chelates.

artículo científico publicado en 2004

Mannich Reaction as a New Route to Pyridine-Based Polyaminocarboxylic Ligands

artículo científico publicado en 2004

Maximizing the relaxivity of HSA-bound gadolinium complexes by simultaneous optimization of rotation and water exchange

artículo científico publicado en 2007

Mesoporous silica nanoparticles functionalized with fluorescent and MRI reporters for the visualization of murine tumors overexpressing αvβ3 receptors

artículo científico publicado en 2016

Metal containing nanosized systems for MR-Molecular Imaging applications

Methods for an improved detection of the MRI-CEST effect

artículo científico publicado en 2009

Mn-loaded apoferritin: a highly sensitive MRI imaging probe for the detection and characterization of hepatocarcinoma lesions in a transgenic mouse model

artículo científico publicado en 2012

Modifying LnHPDO3A Chelates for Improved T1 and CEST MRI Applications

artículo científico publicado en 2019

Modulation of the antioxidant activity of HO* scavengers by albumin binding: a 19F-NMR study.

artículo científico publicado en 2003

Modulation of the water exchange rates in [Gd–DO3A] complex by formation of ternary complexes with carboxylate ligands

Molecular recognition of sugars by lanthanide (III) complexes of a conjugate of N, N-bis[2-[bis[2-(1, 1-dimethylethoxy)-2-oxoethyl]amino]ethyl]glycine and phenylboronic acid

artículo científico publicado en 2007

NMR Studies of Melanins: Characterization of a Soluble Melanin Free Acid From Sepia Ink ⬇️

artículo científico publicado el 1 de diciembre de 1991

NMR investigation of the equilibrium partitioning of a water-soluble bile salt protein carrier to phospholipid vesicles

artículo científico publicado en 2013

NMR relaxometric investigation on human methemoglobin and fluoromethemoglobin. An improved quantitative in vitro assay of human methemoglobin.

artículo científico publicado en 1995

NMR relaxometric investigations of solid lipid nanoparticles (SLN) containing gadolinium(III) complexes.

artículo científico publicado en 1998

NMR structural studies of the supramolecular adducts between a liver cytosolic bile acid binding protein and gadolinium(III)-chelates bearing bile acids residues: molecular determinants of the binding of a hepatospecific magnetic resonance imaging c

artículo científico publicado en 2007

NMR structure of two novel polyethylene glycol conjugates of the human growth hormone-releasing factor, hGRF(1-29)-NH2.

artículo científico publicado en 2003

NMR, Relaxometric, and Structural Studies of the Hydration and Exchange Dynamics of Cationic Lanthanide Complexes of Macrocyclic Tetraamide Ligands

scientific article published in 1999

Nanoparticle-based chemical exchange saturation transfer (CEST) agents

artículo científico publicado en 2013

Nature-inspired particles as carriers for multimodal molecular imaging applications

Neural-cell adhesion molecule (NCAM) expression by immature and tumor-derived endothelial cells favors cell organization into capillary-like structures

artículo científico publicado en 2006

New cyclodextrin dimers and trimers capable of forming supramolecular adducts with shape-specific ligands

artículo científico publicado en 2008

New hyperpolarized contrast agents for 13C-MRI from para-hydrogenation of oligooxyethylenic alkynes

artículo científico publicado en 2008

New insights for pursuing high relaxivity MRI agents from modelling the binding interaction of Gd(III) chelates to HSA

artículo científico publicado en 2005

New paramagnetic supramolecular adducts for MRI applications based on non-covalent interactions between Gd(III)-complexes and beta- or gamma-cyclodextrin units anchored to chitosan.

artículo científico publicado en 2006

NorDATA: An original ligand based on the norbornane skeleton. Synthesis and thermodynamic characterization of metal complexes

Novel Contrast Agents for Magnetic Resonance Imaging. Synthesis and Characterization of the Ligand BOPTA and Its Ln(III) Complexes (Ln = Gd, La, Lu). X-ray Structure of Disodium (TPS-9-145337286-C-S)-[4-Carboxy-5,8,11-tris(carboxymethyl)-1-phenyl-2-o

article published in 1995

Novel paramagnetic macromolecular complexes derived from the linkage of a macrocyclic Gd(III) complex to polyamino acids through a squaric acid moiety.

artículo científico publicado en 1999

Nuclear magnetic relaxation dispersion profiles of substantia nigra pars compacta in Parkinson's disease patients are consistent with protein aggregation.

artículo científico publicado en 2000

Nuclear magnetic resonance studies of neutral lanthanide(III) complexes with tetraaza-macrocyclic ligands containing three phosphinate and one carboxamide co-ordinating arms

Nuclear magnetic resonance, luminescence and structural studies of lanthanide complexes with octadentate macrocyclic ligands bearing benzylphosphinate groups

On the fate of MRI Gd-based contrast agents in cells. Evidence for extensive degradation of linear complexes upon endosomal internalization.

artículo científico publicado en 2013

On the role of the counter-ion in defining water structure and dynamics: order, structure and dynamics in hydrophilic and hydrophobic gadolinium salt complexes

artículo científico publicado en 2006

One-step synthesis of a new eight-membered cyclic ligand from glycine, formaldehyde and hypophosphorous acid

Optimization of the Relaxivity of MRI Contrast Agents: Effect of Poly(ethylene glycol) Chains on the Water-Exchange Rates of GdIII Complexes ⬇️

artículo científico publicado el 31 de octubre de 2001

Optimized relaxivity and stability of [Gd(H(2,2)-1,2-HOPO)(H2O)]- for use as an MRI contrast agent.

artículo científico publicado en 2007

Optimizing the high-field relaxivity by self-assembling of macrocyclic Gd(III) complexes

artículo científico publicado en 2015

Osmotically shrunken LIPOCEST agents: an innovative class of magnetic resonance imaging contrast media based on chemical exchange saturation transfer.

artículo científico publicado en 2009

Oximation of acetyl(hydroxyimino)acetone: nuclear magnetic resonance spectroscopic, chemical, and X-ray crystallographic studies of the reaction products

Para-hydrogen induced polarization of Si-29 NMR resonances as a potentially useful tool for analytical applications

scientific article published on 24 June 2012

Para-hydrogenated glucose derivatives as potential 13C-hyperpolarized probes for magnetic resonance imaging.

artículo científico publicado en 2010

ParaHydrogen Induced Polarization of 13C carboxylate resonance in acetate and pyruvate

artículo científico publicado en 2015

Paramagnetic CEST MRI Contrast Agents

Paramagnetic lanthanide(III) complexes as pH-sensitive chemical exchange saturation transfer (CEST) contrast agents for MRI applications

artículo científico publicado en 2002

Paramagnetic liposomes as innovative contrast agents for magnetic resonance (MR) molecular imaging applications

artículo científico publicado en 2008

Paramagnetic self-assembled nanoparticles as supramolecular MRI contrast agents

artículo científico publicado en 2012

Peptide Derivatized Lamellar Aggregates as Target-Specific MRI Contrast Agents

artículo científico publicado en 2007

Picture of a chelate in exchange: the crystal structure of NaHoDOTMA, a 'semi'-hydrated chelate.

artículo científico publicado en 2013

Platinum(II)-gadolinium(III) complexes as potential single-molecular theranostic agents for cancer treatment

artículo científico publicado en 2014

Polarization transfer from para-hydrogen to heteronuclei: effect of H/D substitution. The case of AA'X and A2A2'X spin systems

scientific article published on 18 October 2005

Poly-beta-cyclodextrin based platform for pH mapping via a ratiometric 19F/1H MRI method

artículo científico publicado en 2009

Polymeric vesicles loaded with gadoteridol as reversible and concentration-independent magnetic resonance imaging thermometers

artículo científico publicado en 2014

Preparation and in vitro characterization of chitosan nanobubbles as theranostic agents.

artículo científico publicado en 2015

Probing protein conformation in cells by EPR distance measurements using Gd3+ spin labeling.

artículo científico publicado en 2014

Properties, Solution State Behavior, and Crystal Structures of Chelates of DOTMA ⬇️

artículo científico publicado el 5 de agosto de 2011

Proteomics as a tool to improve investigation of substantial equivalence in genetically modified organisms: the case of a virus-resistant tomato.

artículo científico publicado en 2004

Prototropic and Water-Exchange Processes in Aqueous Solutions of Gd(III) Chelates

PrototropicvsWhole Water Exchange Contributions to the Solvent Relaxation Enhancement in the Aqueous Solution of a Cationic Gd3+Macrocyclic Complex

scientific article published in 1997

Pushing the sensitivity envelope of lanthanide-based magnetic resonance imaging (MRI) contrast agents for molecular imaging applications

artículo científico publicado en 2009

Quantification of the expression level of integrin receptor alpha(v)beta3 in cell lines and MR imaging with antibody-coated iron oxide particles.

artículo científico publicado en 2006

Quantitative description of radiofrequency (RF) power-based ratiometric chemical exchange saturation transfer (CEST) pH imaging

artículo científico publicado en 2015

Re-evaluation of the water exchange lifetime value across red blood cell membrane.

artículo científico publicado en 2015

Reduction/dissolution of a beta-MnOOH nanophase in the ferritin cavity to yield a highly sensitive, biologically compatible magnetic resonance imaging agent

scientific article published on 01 January 2010

Relaxometric and luminescence behaviour of triaquahexaazamacrocyclic complexes, the gadolinium complex displaying a high relaxivity with a pronounced pH dependence

Relaxometric and modelling studies of the binding of a lipophilic Gd-AAZTA complex to fatted and defatted human serum albumin

artículo científico publicado en 2007

Relaxometric and solution NMR structural studies on ditopic lanthanide(III) complexes of a phosphinate analogue of DOTA with a fast rate of water exchange.

artículo científico publicado en 2006

Relaxometric characterization of human hemalbumin.

artículo científico publicado en 2001

Relaxometric evaluation of novel manganese(II) complexes for application as contrast agents in magnetic resonance imaging

artículo científico publicado en 2001

Relaxometric investigations and MRI evaluation of a liposome-loaded pH-responsive gadolinium(III) complex

artículo científico publicado en 2012

Relaxometric studies for food characterization: the case of balsamic and traditional balsamic vinegars

artículo científico publicado en 2009

Release of a Paramagnetic Magnetic Resonance Imaging Agent from Liposomes Triggered by Low Intensity Non-Focused Ultrasound

Release of toxic Gd3+ ions to tumour cells by vitamin B12 bioconjugates.

artículo científico publicado en 2009

Role of the reaction intermediates in determining PHIP (parahydrogen induced polarization) effect in the hydrogenation of acetylene dicarboxylic acid with the complex [Rh (dppb)]+ (dppb: 1,4-bis(diphenylphosphino)butane)

artículo científico publicado en 2014

SPECT imaging of fibrin using fibrin-binding peptides

artículo científico publicado en 2013

Sensitive MRI detection of internalized T1 contrast agents using magnetization transfer contrast.

artículo científico publicado en 2015

Separation of intra- and extracellular lactate NMR signals using a lanthanide shift reagent

artículo científico publicado en 2002

Simultaneous MR imaging for tissue engineering in a rat model of stroke

artículo científico publicado en 2015

Slow clearance gadolinium-based extracellular and intravascular contrast media for three-dimensional MR angiography.

artículo científico publicado en 2001

Society Spotlight: European Commission-supported Development of Targeted Nanomedicines: did MediTrans Make a difference? ⬇️

artículo científico publicado el 1 de julio de 2011

Solid-state 31P CP/MAS NMR vs. solution study of bis(tertiary phosphines)

artículo científico publicado en 1993

Solution Structures, Stabilities, Kinetics, and Dynamics of DO3A and DO3A–Sulphonamide Complexes

article

Solution and Solid-State Characterization of Highly Rigid, Eight-Coordinate Lanthanide(III) Complexes of a Macrocyclic Tetrabenzylphosphinate

article published in 1994

Solution structure of the supramolecular adduct between a liver cytosolic bile acid binding protein and a bile acid-based gadolinium(III)-chelate, a potential hepatospecific magnetic resonance imaging contrast agent

artículo científico publicado en 2008

Sonosensitive theranostic liposomes for preclinical in vivo MRI-guided visualization of doxorubicin release stimulated by pulsed low intensity non-focused ultrasound

artículo científico publicado en 2015

Stabilization of the T-state of ferrous human adult and fetal hemoglobin by Ln(III) complexes: a thermodynamic study

artículo científico publicado en 1998

Structural determinants of fluoride and formate binding to hemoglobin and myoglobin: crystallographic and 1H-NMR relaxometric study.

artículo científico publicado en 1996

Structural variations across the lanthanide series of macrocyclic DOTA complexes: insights into the design of contrast agents for magnetic resonance imaging.

artículo científico publicado en 2003

Structural, luminescence, and NMR studies of the reversible binding of acetate, lactate, citrate, and selected amino acids to chiral diaqua ytterbium, gadolinium, and europium complexes

artículo científico publicado en 2002

Structure and relaxivity of macrocyclic gadolinium complexes incorporating pyridyl and 4-morpholinopyridyl substituents

Structure-Function Relationships of Iodinated Contrast Media and Risk of Nephrotoxicity ⬇️

artículo científico publicado el 1 de enero de 2012

Substituent effects on Gd(III)-based MRI contrast agents: optimizing the stability and selectivity of the complex and the number of coordinated water molecules.

artículo científico publicado en 2006

Successful entrapping of liposomes in glucan particles: an innovative micron-sized carrier to deliver water-soluble molecules

artículo científico publicado en 2014

Supramolecular Adducts between Poly‐L‐arginine and [TmIIIdotp]: A Route to Sensitivity‐Enhanced Magnetic Resonance Imaging–Chemical Exchange Saturation Transfer Agents ⬇️

artículo científico publicado el 29 de septiembre de 2003

Supramolecular Adducts of Negatively Charged Lanthanide(III) DOTP Chelates and Cyclodextrins Functionalized with Ammonium Groups: Mass Spectrometry and Nuclear Magnetic Resonance Studies

article

Supramolecular protamine/Gd-loaded liposomes adducts as relaxometric protease responsive probes

artículo científico publicado en 2010

Synthesis and Characterization of Triosmium Clusters Containing the Bidentate Ligand Ph2PCH2CH2SMe: Detection of an Isomerization Reaction Involving Bridging and Chelating Ligand Coordination Modes

Synthesis and characterization of a Gd(III) based contrast agent responsive to thiol containing compounds.

artículo científico publicado en 2007

Synthesis and characterization of an MRI Gd-based probe designed to target the translocator protein.

artículo científico publicado en 2013

Synthesis and physicochemical characterization of carbon backbone modified [Gd(TTDA)(H2O)]2- derivatives

artículo científico publicado en 2011

Synthesis and relaxometric characterization of a MRI Gd-based probe responsive to glutamic acid decarboxylase enzymatic activity.

artículo científico publicado en 2013

Synthesis and solution thermodynamic study of rigidified and functionalised EGTA derivatives

artículo científico publicado en 2008

Synthesis and testing of a p‐H2 hyperpolarized 13C probe based on the pyrazolo[1,5‐a]pyrimidineacetamide DPA‐713, an MRI vector to target the peripheral benzodiazepine receptors ⬇️

artículo científico publicado el 17 de noviembre de 2011

Synthesis of Gd(III)-C-palmitamidomethyl-C'-DOTAMA-C(6)-o-carborane: a new dual agent for innovative MRI/BNCT applications.

artículo científico publicado en 2008

Synthesis of a carborane-containing cholesterol derivative and evaluation as a potential dual agent for MRI/BNCT applications.

artículo científico publicado en 2014

Synthesis of new polyoxapolycarboxylic ligands for lanthanide(III) ions complexation

Synthesis of the Gd(III) complex with a tetrazole-armed macrocyclic ligand as a potential MRI contrast agent

Synthesis, NMR, relaxometry and circularly polarised luminescence studies of macrocyclic monoamidetris(phosphinate) complexes bearing a remote chiral centre

Target visualization by MRI using the avidin/biotin amplification route: synthesis and testing of a biotin-Gd-DOTA monoamide trimer

artículo científico publicado en 2010

Targeting exofacial protein thiols with Gd(III) complexes. An efficient procedure for MRI cell labelling.

artículo científico publicado en 2009

Targeting ferritin receptors for the selective delivery of imaging and therapeutic agents to breast cancer cells.

artículo científico publicado en 2015

Targeting of human renal tumor-derived endothelial cells with peptides obtained by phage display

artículo científico publicado en 2007

Ternary complexes between cationic GdIII chelates and anionic metabolites in aqueous solution: an NMR relaxometric study

artículo científico publicado en 2003

The Role of Equilibrium and Kinetic Properties in the Dissociation of Gd[DTPA-bis(methylamide)] (Omniscan) at near to Physiological Conditions

artículo científico publicado en 2015

The Role of the Amino Protecting Group during Parahydrogenation of Protected Dehydroamino Acids

artículo científico publicado en 2015

The Selectivity of Reversible Oxy-Anion Binding in Aqueous Solution at a Chiral Europium and Terbium Center: Signaling of Carbonate Chelation by Changes in the Form and Circular Polarization of Luminescence Emission

scholarly article by James I. Bruce et al published October 2000 in Journal of the American Chemical Society

The effect of ligand scaffold size on the stability of tripodal hydroxypyridonate gadolinium complexes.

artículo científico publicado en 2003

The effects of intramolecular H-bond formation on the stability constant and water exchange rate of the Gd(III)-diethylenetriamine-N'-(3-amino-1,1-propylenephosphonic)-N, N,N'',N''-tetraacetate complex

artículo científico publicado en 2007

The hydroboration reaction as a key for a straightforward synthesis of new MRI-NCT agents

The release of Doxorubicin from liposomes monitored by MRI and triggered by a combination of US stimuli led to a complete tumor regression in a breast cancer mouse model.

artículo científico publicado en 2016

The structure of the sugar residue in glycated human serum albumin and its molecular recognition by phenylboronate

artículo científico publicado en 2003

The use of contrast agents with fast field-cycling magnetic resonance imaging.

artículo científico publicado en 2010

Theranostic nanomedicine.

artículo científico publicado en 2011

Thermodynamic analysis of hydration in human serum heme-albumin

artículo científico publicado en 2009

Towards a successful clinical implementation of fluorescence-guided surgery

artículo científico publicado en 2014

Towards improved boron neutron capture therapy agents: evaluation of in vitro cellular uptake of a glutamine-functionalized carborane.

artículo científico publicado en 2009

Towards targeted MRI: new MRI contrast agents for sialic acid detection

artículo científico publicado en 2004

Tunable imaging of cells labeled with MRI-PARACEST agents.

artículo científico publicado en 2005

Tuning the coordination number of hydroxypyridonate-based gadolinium complexes: implications for MRI contrast agents.

artículo científico publicado en 2006

Use of labile precursors for the generation of hyperpolarized molecules from hydrogenation with parahydrogen and aqueous-phase extraction.

artículo científico publicado en 2011

Variation of water exchange dynamics with ligand structure and stereochemistry in lanthanide complexes based on 1,4-diazepine derivatives

artículo científico publicado en 2009

Water exchange across the erythrocyte plasma membrane studied by HR-MAS NMR spectroscopy.

artículo científico publicado en 2006

Well-defined, multifunctional nanostructures of a paramagnetic lipid and a lipopeptide for macrophage imaging.

artículo científico publicado en 2009

YbIII-HPDO3A: A Dual pH- and Temperature-Responsive CEST Agent

artículo científico publicado en 2011

Yeast cell wall particles: a promising class of nature-inspired microcarriers for multimodal imaging

artículo científico publicado en 2011

[Gd-AAZTA]-: A New Structural Entry for an Improved Generation of MRI Contrast Agents

artículo científico publicado en 2004

[GdPCP2A(H(2)O)(2)](-): a paramagnetic contrast agent designed for improved applications in magnetic resonance imaging.

artículo científico publicado en 2000

[Yb(AAZTA)(H2O)]-: an unconventional ParaCEST MRI probe

artículo científico publicado en 2018

para-Hydrogenation of unsaturated moieties on poly(lysine) derived substrates for the development of novel hyperpolarized MRI contrast agents

artículo científico publicado en 2005

α-trideuteromethyl[15N]glutamine: A long-lived hyperpolarized perfusion marker.

artículo científico publicado en 2016

β-Gal gene expression MRI reporter in melanoma tumor cells. Design, synthesis, and in vitro and in vivo testing of a Gd(III) containing probe forming a high relaxivity, melanin-like structure upon β-Gal enzymatic activation.

artículo científico publicado en 2011

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