Lista de obras - Karen J Shaw - Dominio Público Uruguay

A novel family of Escherichia coli toxin-antitoxin gene pairs

artículo científico publicado en 2003

Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome

artículo científico publicado en 2014

Aminoglycoside resistance genes aph(2")-Ib and aac(6')-Im detected together in strains of both Escherichia coli and Enterococcus faecium.

artículo científico publicado en 2001

Analysis of beta-glucans and chitin in a Saccharomyces cerevisiae cell wall mutant using high-performance liquid chromatography.

artículo científico publicado en 1994

Analysis of the aac(3)-VIa gene encoding a novel 3-N-acetyltransferase.

artículo científico publicado en 1993

Anthracimycin activity against contemporary methicillin-resistant Staphylococcus aureus

artículo científico publicado en 2014

Comparison of the changes in global gene expression of Escherichia coli induced by four bactericidal agents.

artículo científico publicado en 2003

Correlation between aminoglycoside resistance profiles and DNA hybridization of clinical isolates.

artículo científico publicado en 1991

Determination of aminoglycoside resistance mechanisms of Enterobacteriaceae isolated from a hospital in Hong Kong with antibiogram and genotyping.

artículo científico publicado en 1993

Diversity of aminoglycoside resistance in Enterobacter cloacae in Greece

artículo científico publicado el 1 de febrero de 1992

Elevated Linezolid Resistance in Clinical cfr -Positive Staphylococcus aureus Isolates Is Associated with Co-Occurring Mutations in Ribosomal Protein L3 ⬇️

artículo científico publicado el 13 de septiembre de 2010

Evaluation of the metS and murB loci for antibiotic discovery using targeted antisense RNA expression analysis in Bacillus anthracis.

artículo científico publicado en 2007

Evernimicin (SCH27899) inhibits a novel ribosome target site: analysis of 23S ribosomal DNA mutants.

artículo científico publicado en 2000

Genetic Environment and Stability of cfr in Methicillin-Resistant Staphylococcus aureus CM05 ⬇️

artículo científico publicado el 24 de octubre de 2011

Genetic analysis of bacterial acetyltransferases: identification of amino acids determining the specificities of the aminoglycoside 6'-N-acetyltransferase Ib and IIa proteins ⬇️

artículo científico publicado el 1 de mayo de 1992

Identification and characterization of linezolid-resistant cfr-positive Staphylococcus aureus USA300 isolates from a New York City medical center

artículo científico publicado en 2014

Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design

artículo científico publicado en 2013

Identifying the targets of aminoacyl-tRNA synthetase inhibitors by primer extension inhibition.

artículo científico publicado en 2013

In vitro activity of TR-700, the antibacterial moiety of the prodrug TR-701, against linezolid-resistant strains.

artículo científico publicado en 2008

In vitro and in vivo Evaluation of the Antifungal Activity of APX001A/APX001 Against Candida auris

artículo científico publicado en 2018

Low Fitness Cost of the Multidrug Resistance Gene cfr ⬇️

artículo científico publicado el 6 de junio de 2011

Mutations in ribosomal protein L16 conferring reduced susceptibility to evernimicin (SCH27899): implications for mechanism of action.

artículo científico publicado en 2000

Mutations in ribosomal protein L3 are associated with oxazolidinone resistance in staphylococci of clinical origin.

artículo científico publicado en 2009

Novel pyrazole derivatives as potent inhibitors of type II topoisomerases. Part 1: synthesis and preliminary SAR analysis

scientific article published on 06 March 2007

Novel ribosomal mutations in Staphylococcus aureus strains identified through selection with the oxazolidinones linezolid and torezolid (TR-700).

artículo científico publicado en 2009

Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE), Part II: development of inhibitors with broad spectrum, Gram-negative antibacterial activity.

artículo científico publicado en 2012

Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity

artículo científico publicado en 2013

Regulated secretion of MuGM-CSF in Saccharomyces cerevisiae via GAL1:MF alpha 1 prepro sequences

artículo científico publicado en 1988

Results of the surveillance of Tedizolid activity and resistance program: in vitro susceptibility of gram-positive pathogens collected in 2011 and 2012 from the United States and Europe.

artículo científico publicado en 2014

Simultaneous analysis of host and pathogen interactions during an in vivo infection reveals local induction of host acute phase response proteins, a novel bacterial stress response, and evidence of a host-imposed metal ion limited environment

artículo científico publicado en 2004

Structure-activity relationships of diverse oxazolidinones for linezolid-resistant Staphylococcus aureus strains possessing the cfr methyltransferase gene or ribosomal mutations.

artículo científico publicado en 2010

Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines

artículo científico publicado en 2011

Structure-based design of new dihydrofolate reductase antibacterial agents: 7-(benzimidazol-1-yl)-2,4-diaminoquinazolines

artículo científico publicado en 2014

Tedizolid for the management of human infections: in vitro characteristics.

artículo científico publicado en 2014

Tetrahydroindazole inhibitors of bacterial type II topoisomerases. Part 2: SAR development and potency against multidrug-resistant strains

scientific article published on 06 March 2007

The oxazolidinones: past, present, and future.

artículo científico

Transcriptional profiling and drug discovery.

artículo científico publicado en 2003

Tricyclic GyrB/ParE (TriBE) inhibitors: a new class of broad-spectrum dual-targeting antibacterial agents

artículo científico publicado en 2013

Lista de obras de Karen J Shaw

A novel family of Escherichia coli toxin-antitoxin gene pairs

Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome

Aminoglycoside resistance genes aph(2")-Ib and aac(6')-Im detected together in strains of both Escherichia coli and Enterococcus faecium.

Analysis of beta-glucans and chitin in a Saccharomyces cerevisiae cell wall mutant using high-performance liquid chromatography.

Analysis of the aac(3)-VIa gene encoding a novel 3-N-acetyltransferase.

Anthracimycin activity against contemporary methicillin-resistant Staphylococcus aureus

Comparison of the changes in global gene expression of Escherichia coli induced by four bactericidal agents.

Correlation between aminoglycoside resistance profiles and DNA hybridization of clinical isolates.

Determination of aminoglycoside resistance mechanisms of Enterobacteriaceae isolated from a hospital in Hong Kong with antibiogram and genotyping.

Diversity of aminoglycoside resistance in Enterobacter cloacae in Greece

Elevated Linezolid Resistance in Clinical cfr -Positive Staphylococcus aureus Isolates Is Associated with Co-Occurring Mutations in Ribosomal Protein L3 ⬇️

Evaluation of the metS and murB loci for antibiotic discovery using targeted antisense RNA expression analysis in Bacillus anthracis.

Evernimicin (SCH27899) inhibits a novel ribosome target site: analysis of 23S ribosomal DNA mutants.

Genetic Environment and Stability of cfr in Methicillin-Resistant Staphylococcus aureus CM05 ⬇️

Genetic analysis of bacterial acetyltransferases: identification of amino acids determining the specificities of the aminoglycoside 6'-N-acetyltransferase Ib and IIa proteins ⬇️

Identification and characterization of linezolid-resistant cfr-positive Staphylococcus aureus USA300 isolates from a New York City medical center

Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design

Identifying the targets of aminoacyl-tRNA synthetase inhibitors by primer extension inhibition.

In vitro activity of TR-700, the antibacterial moiety of the prodrug TR-701, against linezolid-resistant strains.

In vitro and in vivo Evaluation of the Antifungal Activity of APX001A/APX001 Against Candida auris

Low Fitness Cost of the Multidrug Resistance Gene cfr ⬇️

Mutations in ribosomal protein L16 conferring reduced susceptibility to evernimicin (SCH27899): implications for mechanism of action.

Mutations in ribosomal protein L3 are associated with oxazolidinone resistance in staphylococci of clinical origin.

Novel pyrazole derivatives as potent inhibitors of type II topoisomerases. Part 1: synthesis and preliminary SAR analysis

Novel ribosomal mutations in Staphylococcus aureus strains identified through selection with the oxazolidinones linezolid and torezolid (TR-700).

Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE), Part II: development of inhibitors with broad spectrum, Gram-negative antibacterial activity.

Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity

Regulated secretion of MuGM-CSF in Saccharomyces cerevisiae via GAL1:MF alpha 1 prepro sequences

Results of the surveillance of Tedizolid activity and resistance program: in vitro susceptibility of gram-positive pathogens collected in 2011 and 2012 from the United States and Europe.

Simultaneous analysis of host and pathogen interactions during an in vivo infection reveals local induction of host acute phase response proteins, a novel bacterial stress response, and evidence of a host-imposed metal ion limited environment

Structure-activity relationships of diverse oxazolidinones for linezolid-resistant Staphylococcus aureus strains possessing the cfr methyltransferase gene or ribosomal mutations.

Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines

Structure-based design of new dihydrofolate reductase antibacterial agents: 7-(benzimidazol-1-yl)-2,4-diaminoquinazolines

Tedizolid for the management of human infections: in vitro characteristics.

Tetrahydroindazole inhibitors of bacterial type II topoisomerases. Part 2: SAR development and potency against multidrug-resistant strains

The oxazolidinones: past, present, and future.

Transcriptional profiling and drug discovery.

Tricyclic GyrB/ParE (TriBE) inhibitors: a new class of broad-spectrum dual-targeting antibacterial agents