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Lista de obras de Olivier Mirguet

A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins

article by Anne-Caroline Chany et al published 30 November 2011 in Chemistry—A European Journal

A new AMPK activator, GSK773, corrects fatty acid oxidation and differentiation defect in CPT2-deficient myotubes

scientific article published on 01 October 2018

A short formal synthesis of paroxetine. Diastereoselective cuprate addition to a chiral racemic olefinic amido ester

article

Comparison of soluble guanylate cyclase stimulators and activators in models of cardiovascular disease associated with oxidative stress.

artículo científico publicado en 2012

Design and synthesis of bridged piperidine and piperazine isosteres

artículo científico publicado en 2018

Desymmetrization of hydrazinocyclohexadienes: a new approach for the synthesis of polyhydroxylated aminocyclohexanes

artículo científico publicado en 2009

Development of a Series of Kynurenine 3-Monooxygenase Inhibitors Leading to a Clinical Candidate for the Treatment of Acute Pancreatitis.

artículo científico publicado en 2017

Diastereoselective conjugate addition of organocuprates to chiral racemic olefinic amido esters. Formal total synthesis of paroxetine

article

Discovery and characterization of small molecule inhibitors of the BET family bromodomains

artículo científico publicado en 2011

Discovery of Pyridones As Oral AMPK Direct Activators

artículo científico publicado en 2013

Discovery of epigenetic regulator I-BET762: lead optimization to afford a clinical candidate inhibitor of the BET bromodomains

artículo científico publicado en 2013

From ApoA1 upregulation to BET family bromodomain inhibition: discovery of I-BET151.

artículo científico publicado en 2012

Identification of a novel series of BET family bromodomain inhibitors: binding mode and profile of I-BET151 (GSK1210151A)

artículo científico publicado en 2012

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

artículo científico publicado en 2011

Juniperanol: First total synthesis and evaluation in Type 2 Diabetes disease

artículo científico publicado en 2019

Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis

artículo científico publicado en 2016

Naphthyridines as novel BET family bromodomain inhibitors

artículo científico publicado en 2014

Rearrangement of beta-amino alcohols and application to the synthesis of biologically active compounds.

artículo científico publicado en 2009

Ring expansion: formal total synthesis of (−)-paroxetine

The discovery of I-BET726 (GSK1324726A), a potent tetrahydroquinoline ApoA1 up-regulator and selective BET bromodomain inhibitor

artículo científico publicado en 2014

The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitis

artículo científico publicado en 2017