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Lista de obras de Patrick Auberger

(13)C/(12)C isotope ratios of organic acids, glucose and fructose determined by HPLC-co-IRMS for lemon juices authenticity

artículo científico publicado en 2013

A Jurkat T cell variant resistant to death receptor-induced apoptosis. Correlation with heat shock protein (Hsp) 27 and 70 levels.

artículo científico publicado en 2001

A New Hydroxylated Nonaprenylhydroquinone from the Mediterranean Marine Sponge Sarcotragus spinosulus

artículo científico publicado el 7 de julio de 2011

A chymotryptic-type protease inhibitor decreases interleukin 2 synthesis and induces prostaglandin production in Jurkat T cells

scientific article published on 01 January 1989

A chymotryptic-type serine protease is required for IL-2 production by Jurkat T cells.

artículo científico publicado en 1990

A new posttranslational regulation of REDD1/DDIT4 through cleavage by caspase 3 modifies its cellular function

artículo científico publicado en 2014

A survey of the signaling pathways involved in megakaryocytic differentiation of the human K562 leukemia cell line by molecular and c-DNA array analysis.

artículo científico publicado en 2006

AMPK- and p62/SQSTM1-dependent autophagy mediate resveratrol-induced cell death in chronic myelogenous leukemia.

artículo científico publicado en 2010

ATP-competitive Plk1 inhibitors induce caspase 3-mediated Plk1 cleavage and activation in hematopoietic cell lines.

artículo científico publicado en 2017

Acadesine Circumvents Azacitidine Resistance in Myelodysplastic Syndrome and Acute Myeloid Leukemia

artículo científico publicado en 2019

Acadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell death

artículo científico publicado en 2009

Active stromelysin-3 (MMP-11) increases MCF-7 survival in three-dimensional Matrigel culture via activation of p42/p44 MAP-kinase

artículo científico publicado en 2003

All tyrosine kinase inhibitor-resistant chronic myelogenous cells are highly sensitive to Ponatinib

artículo científico publicado el 1 de diciembre de 2012

Altered T cell surface glycosylation in HIV-1 infection results in increased susceptibility to galectin-1-induced cell death.

artículo científico publicado en 2003

An absolute requirement for Fyn in T cell receptor-induced caspase activation and apoptosis

scientific article published on 01 August 2001

An miRNA-DNMT1 Axis Is Involved in Azacitidine Resistance and Predicts Survival in Higher-Risk Myelodysplastic Syndrome and Low Blast Count Acute Myeloid Leukemia

artículo científico publicado en 2016

Anti-inflammatory activity of Mitraphylline isolated from Uncaria tomentosa bark

artículo científico publicado en 2012

Apoptosis and autophagy have opposite roles on imatinib-induced K562 leukemia cell senescence.

artículo científico publicado en 2012

Apoptosis and erythroid differentiation triggered by Bcr-Abl inhibitors in CML cell lines are fully distinguishable processes that exhibit different sensitivity to caspase inhibition.

artículo científico publicado en 2006

Autophagy is required for CSF-1-induced macrophagic differentiation and acquisition of phagocytic functions.

artículo científico publicado en 2012

Autophagy, a key mechanism of oncogenesis and resistance in leukemia

artículo científico publicado en 2016

Azacitidine resistance caused by LAMP2 deficiency: a therapeutic window for the use of autophagy inhibitors in MDS/AML patients?

scientific article published on 01 March 2019

Azacitidine-resistant SKM1 myeloid cells are defective for AZA-induced mitochondrial apoptosis and autophagy.

artículo científico publicado en 2011

BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice

artículo científico publicado en 2016

BCL2L10 positive cells in bone marrow are an independent prognostic factor of azacitidine outcome in myelodysplastic syndrome and acute myeloid leukemia

artículo científico publicado en 2017

BCR-ABL/p62/SQSTM1: a cannibal embrace.

artículo científico publicado en 2012

Blocking NF-kappaB activation in Jurkat leukemic T cells converts the survival agent and tumor promoter PMA into an apoptotic effector.

artículo científico publicado en 2002

CD10 (Endopeptidase 24.11) Is a Thymic Peptide-Degrading Enzyme Possibly Involved in the Regulation of Thymocyte Functions

artículo científico publicado en 1997

CD10 inhibitors increase f-Met-Leu-Phe-induced neutrophil transmigration

artículo científico publicado el 1 de marzo de 1998

CD10 is expressed on human thymic epithelial cell lines and modulates thymopentin-induced cell proliferation.

artículo científico publicado en 1997

CD10 plays a specific role in early thymic development

article

Caspase 1/11 Deficiency or Pharmacological Inhibition Mitigates Psoriasis-Like Phenotype in Mice

artículo científico publicado en 2018

Caspase inhibition protects from liver injury following ischemia and reperfusion in rats

artículo científico publicado en 2000

Caspase-3-derived C-terminal product of synphilin-1 displays antiapoptotic function via modulation of the p53-dependent cell death pathway.

artículo científico publicado en 2006

Chaperone-Mediated Autophagy and Its Emerging Role in Hematological Malignancies

scientific article published on 16 October 2019

Characterization and purification of T lymphocyte aminopeptidase B: a putative marker of T cell activation

artículo científico publicado en 1993

Characterization and purification of a guanidinobenzoatase: a possible marker of human renal carcinoma

artículo científico publicado en 1992

Chymotryptic-type protease inhibitors block the increase in Ca2+ and Il-2 production in activated Jurkat T cells

scientific article published on 01 February 1989

Cleavage and relocation of the tyrosine kinase P59FYN during Fas-mediated apoptosis in T lymphocytes

artículo científico publicado en 1999

Cleavage of Fyn and Lyn in their N-terminal unique regions during induction of apoptosis: a new mechanism for Src kinase regulation.

artículo científico publicado en 2001

Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.

artículo científico publicado en 2004

Cleavage of the Serum Response Factor during Death Receptor-induced Apoptosis Results in an Inhibition of the c-FOSPromoter Transcriptional Activity

artículo científico publicado en 2000

Comparative analysis of proteins labelled with [35S]methionine in the liver in vivo and in freshly isolated and short-term-cultured hepatocytes in vitro

artículo científico publicado en 1982

Cooperation of amphiregulin and insulin-like growth factor-1 inhibits Bax- and Bad-mediated apoptosis via a protein kinase C-dependent pathway in non-small cell lung cancer cells.

artículo científico publicado en 2005

DNA Damage and the Activation of the p53 Pathway Mediate Alterations in Metabolic and Secretory Functions of Adipocytes

artículo científico publicado en 2016

Differential SP220K expression in renal carcinoma and oncocytoma cells

scientific article published on 01 September 1997

Differential requirements for ERK1/2 and P38 MAPK activation by thrombin in T cells. Role of P59Fyn and PKCepsilon.

artículo científico publicado en 2001

Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell death

artículo científico publicado en 2016

Distinct mechanisms regulate 5-HT2 and thrombin receptor desensitization.

artículo científico publicado en 1995

Downregulation of caspases and Fas ligand expression, and increased lifespan of neutrophils after transmigration across intestinal epithelium.

artículo científico publicado en 2003

Dual role of Sp3 transcription factor as an inducer of apoptosis and a marker of tumour aggressiveness

artículo científico publicado en 2009

Effect of Caspase Inhibition on Thymic Apoptosis in Hemorrhagic Shock

artículo científico publicado en 2007

Effects of growth factors on hormonal stimulation of amino acid transport in primary cultures of rat hepatocytes.

artículo científico publicado en 1983

Effects of polyamines on cyclic AMP-mediated stimulation of amino acid transport in isolated rat hepatocytes.

artículo científico publicado en 1983

Endopeptidase 24.11 (CD10/NEP) is required for phorbol ester-induced growth arrest in Jurkat T cells

scientific article published on 01 September 1997

Escherichia coli α-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia

artículo científico publicado en 2015

Evidence for a p23 caspase-cleaved form of p27[KIP1] involved in G1 growth arrest.

artículo científico publicado en 1999

Fas ligand expression following normothermic liver ischemia-reperfusion

artículo científico publicado en 2005

FeCl3-promoted and ultrasound-assisted synthesis of resveratrol O-derived glycoside analogs.

artículo científico publicado en 2014

Gab2 signaling in chronic myeloid leukemia cells confers resistance to multiple Bcr-Abl inhibitors.

artículo científico publicado en 2012

Gene expression profiling of human liver transplants identifies an early transcriptional signature associated with initial poor graft function.

artículo científico publicado en 2008

Gene expression profiling of imatinib and PD166326-resistant CML cell lines identifies Fyn as a gene associated with resistance to BCR-ABL inhibitors.

artículo científico publicado en 2009

Gene expression profiling of normal human pulmonary fibroblasts following coculture with non-small-cell lung cancer cells reveals alterations related to matrix degradation, angiogenesis, cell growth and survival

article

Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation.

artículo científico publicado en 2009

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

Helicobacter pylori Lipopolysaccharide Hinders Polymorphonuclear Leucocyte Apoptosis

scientific article published on 01 March 2001

High levels of functional endopeptidase 24.11 (CD10) activity on human thymocytes: preferential expression on immature subsets

scientific article published on 01 July 1994

How recent advances in high-risk myelodysplastic syndrome physiopathology may impact future treatments.

artículo científico

Human polymorphonuclear leukocytes are sensitive in vitro to Helicobacter pylori vaca toxin

artículo científico publicado en 2006

Hypomethylating agents reactivate FOXO3A in acute myeloid leukemia

artículo científico publicado en 2011

IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential.

artículo científico publicado en 2018

Imatinib induces mitochondria-dependent apoptosis of the Bcr-Abl-positive K562 cell line and its differentiation toward the erythroid lineage.

artículo científico publicado en 2003

Imatinib mesylate (STI571) decreases the vascular endothelial growth factor plasma concentration in patients with chronic myeloid leukemia.

artículo científico publicado en 2004

Imatinib triggers mesenchymal-like conversion of CML cells associated with increased aggressiveness.

artículo científico publicado en 2012

Implication and Regulation of AMPK during Physiological and Pathological Myeloid Differentiation

scientific article published on 30 September 2018

In Vitro and in Vivo Evaluation of Fully Substituted (5-(3-Ethoxy-3-oxopropynyl)-4-(ethoxycarbonyl)-1,2,3-triazolyl-glycosides as Original Nucleoside Analogues to Circumvent Resistance in Myeloid Malignancies

artículo científico publicado en 2017

Induction of different types of cell death after normothermic liver ischemia-reperfusion

scientific article published on 01 December 2010

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.

artículo científico publicado en 2013

Inhibition of apoptosis induced by heat shock preconditioning is associated with decreased phagocytosis in human polymorphonuclear leukocytes through inhibition of Rac and Cdc42

Inhibition of hormonal induction of tyrosine aminotransferase by polyamines in freshly isolated rat hepatocytes.

artículo científico publicado en 1983

Inhibition of imatinib-mediated apoptosis by the caspase-cleaved form of the tyrosine kinase Lyn in chronic myelogenous leukemia cells.

artículo científico publicado en 2009

Inhibition of the NF-kappaB survival pathway via caspase-dependent cleavage of the IKK complex scaffold protein and NF-kappaB essential modulator NEMO.

artículo científico publicado en 2007

Inhibitors of chymotrypsin-like activities selectively block the mitotic pathway in rat hepatoma cells.

artículo científico publicado en 1990

Injection of Staphylococcus aureus EDIN by the Bacillus anthracis protective antigen machinery induces vascular permeability

artículo científico publicado en 2009

Insulin enhances protein phosphorylation in isolated hepatocytes by inhibiting an amiloride sensitive phosphatase

artículo científico publicado en 1982

Insulin regulation of protein phosphorylation in hepatocytes. Studies using two effectors: amiloride and natural aliphatic polyamines.

artículo científico publicado en 1985

Involvement of mast cells in gastritis caused by Helicobacter pylori: a potential role in epithelial cell apoptosis

artículo científico publicado en 2007

Isoform-specific contribution of protein kinase C to prion processing.

artículo científico publicado en 2008

Isolation and characterization of a T lymphocyte mutant defective in the protein kinase C signal transduction pathway.

artículo científico publicado en 1991

Jurkat T cells express a functional neutral endopeptidase activity (CALLA) involved in T cell activation

artículo científico publicado el 1 de noviembre de 1992

LAMP2 expression dictates azacytidine response and prognosis in MDS/AML

artículo científico publicado en 2019

Leukemic cell xenograft in zebrafish embryo for investigating drug efficacy.

artículo científico publicado en 2011

Low-dose vemurafenib induces complete remission in a case of hairy-cell leukemia with a V600E mutation.

artículo científico publicado en 2013

Mechanism of action of the multikinase inhibitor Foretinib.

artículo científico publicado en 2011

Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells

artículo científico publicado el 1 de noviembre de 2011

Metformin inhibits melanoma development through autophagy and apoptosis mechanisms.

artículo científico publicado en 2011

Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1.

artículo científico publicado en 2011

Modular synthesis of new C-aryl-nucleosides and their anti-CML activity

artículo científico publicado en 2018

Monomeric 55-kDa guanidinobenzoatase switches to a serine proteinase activity upon tetramerization. Tetrameric proteinase SP 220 K appears as the native form

scientific article published on 01 May 1994

Monosomal karyotype improves IPSS‐R stratification in MDS and AML patients treated with Azacitidine

artículo científico publicado el 23 de julio de 2013

Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp

artículo científico publicado el 27 de junio de 2013

Nephroblastoma overexpressed/cysteine-rich protein 61/connective tissue growth factor/nephroblastoma overexpressed gene-3 (NOV/CCN3), a selective adrenocortical cell proapoptotic factor, is down-regulated in childhood adrenocortical tumors

artículo científico publicado en 2007

Neprilysin, a novel target for ultraviolet B regulation of melanogenesis via melanocortins

scientific article published on 01 September 2000

Persistent activation of the Fyn/ERK kinase signaling axis mediates imatinib resistance in chronic myelogenous leukemia cells through upregulation of intracellular SPARC.

artículo científico publicado en 2010

Phenotypic and genotypic characterization of azacitidine-sensitive and resistant SKM1 myeloid cell lines

artículo científico publicado en 2014

Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

artículo científico publicado en 2003

Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia

artículo científico publicado en 2015

Ponatinib circumvents all types of imatinib resistance in chronic myelogenous leukemia cell lines.

artículo científico publicado en 2013

Pro-inflammatory proteins S100A9 and tumor necrosis factor-α suppress erythropoietin elaboration in myelodysplastic syndromes

artículo científico publicado en 2017

Proper macrophagic differentiation requires both autophagy and caspase activation.

artículo científico publicado en 2012

Protein kinase activation by warm and cold hypoxia- reoxygenation in primary-cultured rat hepatocytes-JNK(1)/SAPK(1) involvement in apoptosis

artículo científico publicado en 2000

Proteolytic regulation of Forkhead transcription factor FOXO3a by caspase-3-like proteases

artículo científico publicado en 2003

RSK2 is a new Pim2 target with pro-survival functions in FLT3-ITD-positive acute myeloid leukemia.

artículo científico publicado en 2017

Rat liver injury after normothermic ischemia is prevented by a phosphinic matrix metalloproteinase inhibitor

scientific article published on 14 November 2001

Regulation of protein phosphorylation by polyamines in hepatocytes.

artículo científico publicado en 1984

Regulation of thymic development by neprilysin inhibition

artículo científico publicado en 1997

RelB reduces thymocyte apoptosis and regulates terminal thymocyte maturation

artículo científico publicado el 1 de enero de 2002

Resistance to sunitinib in renal clear cell carcinoma results from sequestration in lysosomes and inhibition of the autophagic flux

artículo científico publicado en 2015

Retinoic acid regulates Fas-induced apoptosis in Jurkat T cells: reversal of mitogen-mediated repression of Fas DISC assembly.

artículo científico publicado en 2008

Rho GTPase is activated by cytotoxic necrotizing factor 1 in peripheral blood T lymphocytes: potential cytotoxicity for intestinal epithelial cells

artículo científico publicado en 2003

SP220K is a novel matrix serine proteinase

artículo científico publicado el 17 de julio de 1998

Secretion of a major phosphorylated glycoprotein by hepatocytes. Characterization of specific antibodies and investigations of the processing, excretion kinetics, and phosphorylation

article published in 1985

Sestrin2 integrates Akt and mTOR signaling to protect cells against energetic stress-induced death

artículo científico publicado en 2012

Severe thymic atrophy in a mouse model of skin inflammation accounts for impaired TNFR1 signaling

artículo científico publicado en 2012

Siva-1 and an alternative splice form lacking the death domain, Siva-2, similarly induce apoptosis in T lymphocytes via a caspase-dependent mitochondrial pathway

artículo científico publicado en 2004

Stimulation of the T-cell antigen receptor-CD3 complex signaling pathway by the tyrosine phosphatase inhibitor pervanadate is mediated by inhibition of CD45: evidence for two interconnected Lck/Fyn- or zap-70-dependent signaling pathways.

artículo científico publicado en 1996

Structure elucidation of the new citharoxazole from the Mediterranean deep-sea sponge Latrunculia (Biannulata) citharistae

artículo científico publicado en 2011

Study of a growth hormone-regulated protein secreted by rat hepatocytes: cDNA cloning, anti-protease activity and regulation of its synthesis by various hormones.

artículo científico publicado en 1987

Successful re-treatment of a relapsed V600E mutated HCL patient with low-dose vemurafenib.

artículo científico publicado en 2014

Synthesis and anti-cancer activities of new sulfonamides 4-substituted-triazolyl nucleosides

artículo científico publicado en 2017

T-Cell receptor signaling pathway exerts a negative control on thrombin-mediated increase in [Ca2+]i and p38 MAPK activation in Jurkat T cells: implication of the tyrosine kinase p56Lck.

artículo científico publicado en 1998

Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells

artículo científico publicado en 2010

Targeting lysosomes to eradicate imatinib-resistant chronic myelogenous leukemia cells.

artículo científico publicado en 2010

Targeting the Proteasome-Associated Deubiquitinating Enzyme USP14 Impairs Melanoma Cell Survival and Overcomes Resistance to MAPK-Targeting Therapies

artículo científico publicado en 2018

The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML

artículo científico publicado en 2015

The anti-apoptotic Bcl-B protein inhibits BECN1-dependent autophagic cell death.

artículo científico publicado en 2012

The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level.

artículo científico publicado en 2008

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production

artículo científico publicado el 4 de mayo de 2012

The caspase-cleaved form of LYN mediates a psoriasis-like inflammatory syndrome in mice.

artículo científico publicado en 2009

The cleavage of microphthalmia-associated transcription factor, MITF, by caspases plays an essential role in melanocyte and melanoma cell apoptosis

artículo científico publicado en 2005

The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia.

artículo científico publicado en 2011

The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim.

artículo científico publicado en 2018

The protective effect of phorbol esters on Fas-mediated apoptosis in T cells. Transcriptional and postranscriptional regulation.

artículo científico publicado en 2002

The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells.

artículo científico publicado en 2014

Thrombin and thrombin receptor agonist peptide induce early events of T cell activation and synergize with TCR cross-linking for CD69 expression and interleukin 2 production.

artículo científico

Thrombin and trypsin-induced Ca(2+) mobilization in human T cell lines through interaction with different protease-activated receptors.

artículo científico publicado en 1996

Total genomic alteration as measured by SNP-array-based molecular karyotyping is predictive of overall survival in a cohort of MDS or AML patients treated with azacitidine.

artículo científico publicado en 2013

Transcriptome dysregulation by anthrax lethal toxin plays a key role in induction of human endothelial cell cytotoxicity

artículo científico publicado en 2010

Tumor cell-mediated induction of the stromal factor stromelysin-3 requires heterotypic cell contact-dependent activation of specific protein kinase C isoforms

artículo científico publicado en 2005

Tumor suppressor function of miR-483-3p on squamous cell carcinomas due to its pro-apoptotic properties

artículo científico publicado en 2013

Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha

artículo científico publicado en 1996

Tyrosine phosphorylation of insulin receptor substrates during ischemia/reperfusion-induced apoptosis in rat liver.

artículo científico publicado en 2008

Ultrasound-assisted one-pot synthesis of anti-CML nucleosides featuring 1,2,3-triazole nucleobase under iron-copper catalysis.

artículo científico publicado en 2012

When autophagy meets cancer through p62/SQSTM1.

artículo científico publicado en 2012

[Autophagy, a key player in leukemogenesis and a therapeutic target in hematopoietic malignancies]

artículo científico publicado en 2017

[Inhibition of apoptosis: a new therapeutic approach to prevent liver ischemia-reperfusion lesions?]

scientific article published on 01 June 2000

[Nobel prizes in medicine 2016]

artículo científico publicado en 2016

[Roles and mechanisms of apoptosis in infectious diseases]

scientific article published on 01 September 2000

cIAPs and XIAP reduce RIPKs to silence.

artículo científico publicado en 2014

p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1)-dependent signaling contributes to epithelial skin carcinogenesis.

artículo científico publicado en 2006

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016