Lista de obras - Grazia Graziani - Dominio Público Uruguay

A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib

artículo científico publicado en 2015

Antitumor activity of a novel anti-vascular endothelial growth factor receptor-1 monoclonal antibody that does not interfere with ligand binding

scientific article published on 19 September 2016

Apoptotic and genotoxic effects of a methyl sulfonate ester that selectively generates N3-methyladenine and poly(ADP-ribose) polymerase inhibitors in normal peripheral blood lymphocytes.

artículo científico publicado en 2002

BCG-infected adherent mononuclear cells release cytokines that regulate group 1 CD1 molecule expression

artículo científico publicado en 2006

Beneficial and Detrimental Effects of Antiretroviral Therapy on HIV-Associated Immunosenescence.

artículo científico publicado en 2018

Challenging resistance mechanisms to therapies for metastatic melanoma.

artículo científico publicado en 2013

Chemopotentiation by PARP inhibitors in cancer therapy.

artículo científico publicado en 2005

Cilengitide downmodulates invasiveness and vasculogenic mimicry of neuropilin 1 expressing melanoma cells through the inhibition of αvβ5 integrin.

artículo científico publicado en 2014

Combined effects of adenovirus-mediated wild-type p53 transduction, temozolomide and poly (ADP-ribose) polymerase inhibitor in mismatch repair deficient and non-proliferating tumor cells.

artículo científico publicado en 2001

Combined treatment with temozolomide and poly(ADP-ribose) polymerase inhibitor enhances survival of mice bearing hematologic malignancy at the central nervous system site

artículo científico publicado en 2002

Cytokine-induced expression of CD1b molecules by peripheral blood monocytes: influence of 3'-azido-3'-deoxythymidine.

artículo científico publicado en 1997

Cytotoxicity and Differentiating Effect of the Poly(ADP-Ribose) Polymerase Inhibitor Olaparib in Myelodysplastic Syndromes

artículo científico publicado en 2019

Doping with growth hormone/IGF-1, anabolic steroids or erythropoietin: is there a cancer risk?

artículo científico publicado en 2007

Drug-induced xenogenization of tumors: A possible role in the immune control of malignant cell growth in the brain?

artículo científico publicado en 2018

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

artículo científico publicado en 2016

Editorial

artículo científico publicado en 2015

Effect of hydrocortisone on human natural killer activity and its modulation by beta interferon

scientific article published on 01 January 1988

Effect of rifampin on CD1b expression and double-negative T cell responses against mycobacteria-derived glycolipid antigen.

artículo científico publicado en 1998

Effects of single or split exposure of leukemic cells to temozolomide, combined with poly(ADP-ribose) polymerase inhibitors on cell growth, chromosomal aberrations and base excision repair components.

artículo científico publicado en 2001

Ellagic Acid Inhibits Bladder Cancer Invasiveness and In Vivo Tumor Growth

artículo científico publicado en 2016

Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant.

artículo científico publicado en 2009

Evidence that corticotropin-releasing hormone inhibits cell growth of human breast cancer cells via the activation of CRH-R1 receptor subtype.

artículo científico publicado en 2006

Experimental Evidence of the Antitumor, Antimetastatic and Antiangiogenic Activity of Ellagic Acid

scientific article published on 14 November 2018

Exploiting Microglial Functions for the Treatment of Glioblastoma.

artículo científico publicado en 2016

Expression of the soluble vascular endothelial growth factor receptor-1 in cutaneous melanoma: role in tumour progression.

artículo científico publicado en 2011

Glucocorticoid-induced tumor necrosis factor receptor family-related ligand triggering upregulates vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 and promotes leukocyte adhesion

artículo científico publicado en 2013

High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro

artículo científico publicado en 2017

In vitro combined effects of human interferons and interleukin-2 on natural cell-mediated cytotoxicity ⬇️

artículo científico publicado el 1 de enero de 1993

Influence of MLH1 on colon cancer sensitivity to poly(ADP-ribose) polymerase inhibitor combined with irinotecan.

artículo científico publicado en 2013

Influence of Mycobacterium bovis bacillus Calmette Guérin on in vitro induction of CD1 molecules in human adherent mononuclear cells

artículo científico publicado en 2001

Inhibition of O6-alkylguanine DNA-alkyltransferase or poly(ADP-ribose) polymerase increases susceptibility of leukemic cells to apoptosis induced by temozolomide

artículo científico publicado en 1997

Inhibition of endothelial cell migration and angiogenesis by a vascular endothelial growth factor receptor-1 derived peptide.

artículo científico publicado en 2008

Inhibition of homologous recombination by treatment with BVDU (brivudin) or by RAD51 silencing increases chromosomal damage induced by bleomycin in mismatch repair-deficient tumour cells.

artículo científico publicado en 2009

Inhibition of poly(ADP-ribose) polymerase prevents irinotecan-induced intestinal damage and enhances irinotecan/temozolomide efficacy against colon carcinoma

artículo científico publicado en 2006

Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor

artículo científico publicado en 2003

Ipilimumab: a novel immunostimulatory monoclonal antibody for the treatment of cancer.

artículo científico publicado en 2011

Lead Discovery of Dual G-Quadruplex Stabilizers and Poly(ADP-ribose) Polymerases (PARPs) Inhibitors: A New Avenue in Anticancer Treatment.

artículo científico publicado en 2017

MSH3 expression does not influence the sensitivity of colon cancer HCT116 cell line to oxaliplatin and poly(ADP-ribose) polymerase (PARP) inhibitor as monotherapy or in combination.

artículo científico publicado en 2013

Modulation of GDF11 expression and synaptic plasticity by age and training

artículo científico publicado en 2017

Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers

artículo científico publicado en 2014

N3-methyladenine induces early poly(ADP-ribosylation), reduction of nuclear factor-kappa B DNA binding ability, and nuclear up-regulation of telomerase activity.

artículo científico publicado en 2004

NF-κB is activated in response to temozolomide in an AKT-dependent manner and confers protection against the growth suppressive effect of the drug

artículo científico publicado en 2012

Neuropilin-1 as Therapeutic Target for Malignant Melanoma.

artículo científico

Neuropilin-1 expressing melanoma cells as a model to study the aggressiveness of metastatic melanoma.

artículo científico publicado en 2015

On the Horizon: Targeting Next-Generation Immune Checkpoints for Cancer Treatment

artículo científico publicado en 2019

PARP Inhibitors in Cancer Therapy: Magic Bullets but Moving Targets

artículo científico publicado en 2013

PARP-1 inhibition to treat cancer, ischemia, inflammation

artículo científico publicado en 2005

PARP-1 modulates amyloid beta peptide-induced neuronal damage

artículo científico publicado en 2013

PDIA3 Expression in Glioblastoma Modulates Macrophage/Microglia Pro-Tumor Activation

artículo científico publicado en 2020

Pharmacological inhibition of poly(ADP-ribose) polymerase activity down-regulates the expression of syndecan-4 and Id-1 in endothelial cells.

artículo científico publicado en 2009

Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide

artículo científico publicado en 2014

Placenta growth factor and neuropilin-1 collaborate in promoting melanoma aggressiveness.

artículo científico publicado en 2016

Platelet-derived growth factor C and calpain-3 are modulators of human melanoma cell invasiveness.

artículo científico publicado en 2013

Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide

artículo científico publicado en 2005

Poly(ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis

article

Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells.

artículo científico publicado en 2002

Poly(ADP-ribose) polymerase inhibitor olaparib hampers placental growth factor-driven activation of myelomonocytic cells.

artículo científico publicado en 2018

Poly(ADP-ribose) polymerase signaling of topoisomerase 1-dependent DNA damage in carcinoma cells.

artículo científico publicado en 2010

Potential clinical applications of poly(ADP-ribose) polymerase (PARP) inhibitors.

artículo científico publicado en 2002

Primary cultures of microglial cells for testing toxicity of anticancer drugs.

artículo científico publicado en 2004

Recent approaches to improve the antitumor efficacy of temozolomide.

artículo científico publicado en 2009

Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition

artículo científico publicado en 2012

Role of BRCA Mutations in Cancer Treatment with Poly(ADP-ribose) Polymerase (PARP) Inhibitors

artículo científico publicado en 2018

Role of VEGFR-1 in melanoma acquired resistance to the BRAF inhibitor vemurafenib

artículo científico publicado en 2019

Role of the mismatch repair system and p53 in the clastogenicity and cytotoxicity induced by bleomycin.

artículo científico publicado en 2005

Targeting ADP-ribosylation by PARP inhibitors in acute myeloid leukaemia and related disorders

scientific article published on 24 April 2019

Targeting Tumor-Associated Macrophages to Increase the Efficacy of Immune Checkpoint Inhibitors: A Glimpse into Novel Therapeutic Approaches for Metastatic Melanoma

artículo científico publicado en 2020

Telomerase as a potential anticancer target: growth inhibition and genomic instability.

artículo científico publicado en 2000

The Anti-Vascular Endothelial Growth Factor Receptor-1 Monoclonal Antibody D16F7 Inhibits Glioma Growth and Angiogenesis In Vivo.

artículo científico publicado en 2017

The anti-vascular endothelial growth factor receptor-1 monoclonal antibody D16F7 inhibits invasiveness of human glioblastoma and glioblastoma stem cells

artículo científico publicado en 2017

The glutathione transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma.

artículo científico publicado en 2011

The poly(ADP-ribose) polymerase inhibitor olaparib induces up-regulation of death receptors in primary acute myeloid leukemia blasts by NF-κB activation

scientific article published on 08 March 2018

Therapeutic implication of vascular endothelial growth factor receptor-1 (VEGFR-1) targeting in cancer cells and tumor microenvironment by competitive and non-competitive inhibitors

artículo científico publicado en 2018

Treatment of peripheral blood with staurosporine increases detection of circulating carcinoembryonic antigen positive tumor cells.

artículo científico publicado en 2002

Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome

artículo científico publicado en 2017

Lista de obras de Grazia Graziani

A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib

Antitumor activity of a novel anti-vascular endothelial growth factor receptor-1 monoclonal antibody that does not interfere with ligand binding

Apoptotic and genotoxic effects of a methyl sulfonate ester that selectively generates N3-methyladenine and poly(ADP-ribose) polymerase inhibitors in normal peripheral blood lymphocytes.

BCG-infected adherent mononuclear cells release cytokines that regulate group 1 CD1 molecule expression

Beneficial and Detrimental Effects of Antiretroviral Therapy on HIV-Associated Immunosenescence.

Challenging resistance mechanisms to therapies for metastatic melanoma.

Chemopotentiation by PARP inhibitors in cancer therapy.

Cilengitide downmodulates invasiveness and vasculogenic mimicry of neuropilin 1 expressing melanoma cells through the inhibition of αvβ5 integrin.

Combined effects of adenovirus-mediated wild-type p53 transduction, temozolomide and poly (ADP-ribose) polymerase inhibitor in mismatch repair deficient and non-proliferating tumor cells.

Combined treatment with temozolomide and poly(ADP-ribose) polymerase inhibitor enhances survival of mice bearing hematologic malignancy at the central nervous system site

Cytokine-induced expression of CD1b molecules by peripheral blood monocytes: influence of 3'-azido-3'-deoxythymidine.

Cytotoxicity and Differentiating Effect of the Poly(ADP-Ribose) Polymerase Inhibitor Olaparib in Myelodysplastic Syndromes

Doping with growth hormone/IGF-1, anabolic steroids or erythropoietin: is there a cancer risk?

Drug-induced xenogenization of tumors: A possible role in the immune control of malignant cell growth in the brain?

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

Editorial

Effect of hydrocortisone on human natural killer activity and its modulation by beta interferon

Effect of rifampin on CD1b expression and double-negative T cell responses against mycobacteria-derived glycolipid antigen.

Effects of single or split exposure of leukemic cells to temozolomide, combined with poly(ADP-ribose) polymerase inhibitors on cell growth, chromosomal aberrations and base excision repair components.

Ellagic Acid Inhibits Bladder Cancer Invasiveness and In Vivo Tumor Growth

Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant.

Evidence that corticotropin-releasing hormone inhibits cell growth of human breast cancer cells via the activation of CRH-R1 receptor subtype.

Experimental Evidence of the Antitumor, Antimetastatic and Antiangiogenic Activity of Ellagic Acid

Exploiting Microglial Functions for the Treatment of Glioblastoma.

Expression of the soluble vascular endothelial growth factor receptor-1 in cutaneous melanoma: role in tumour progression.

Glucocorticoid-induced tumor necrosis factor receptor family-related ligand triggering upregulates vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 and promotes leukocyte adhesion

High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro

In vitro combined effects of human interferons and interleukin-2 on natural cell-mediated cytotoxicity ⬇️

Influence of MLH1 on colon cancer sensitivity to poly(ADP-ribose) polymerase inhibitor combined with irinotecan.

Influence of Mycobacterium bovis bacillus Calmette Guérin on in vitro induction of CD1 molecules in human adherent mononuclear cells

Inhibition of O6-alkylguanine DNA-alkyltransferase or poly(ADP-ribose) polymerase increases susceptibility of leukemic cells to apoptosis induced by temozolomide

Inhibition of endothelial cell migration and angiogenesis by a vascular endothelial growth factor receptor-1 derived peptide.

Inhibition of homologous recombination by treatment with BVDU (brivudin) or by RAD51 silencing increases chromosomal damage induced by bleomycin in mismatch repair-deficient tumour cells.

Inhibition of poly(ADP-ribose) polymerase prevents irinotecan-induced intestinal damage and enhances irinotecan/temozolomide efficacy against colon carcinoma

Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor

Ipilimumab: a novel immunostimulatory monoclonal antibody for the treatment of cancer.

Lead Discovery of Dual G-Quadruplex Stabilizers and Poly(ADP-ribose) Polymerases (PARPs) Inhibitors: A New Avenue in Anticancer Treatment.

MSH3 expression does not influence the sensitivity of colon cancer HCT116 cell line to oxaliplatin and poly(ADP-ribose) polymerase (PARP) inhibitor as monotherapy or in combination.

Modulation of GDF11 expression and synaptic plasticity by age and training

Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers

N3-methyladenine induces early poly(ADP-ribosylation), reduction of nuclear factor-kappa B DNA binding ability, and nuclear up-regulation of telomerase activity.

NF-κB is activated in response to temozolomide in an AKT-dependent manner and confers protection against the growth suppressive effect of the drug

Neuropilin-1 as Therapeutic Target for Malignant Melanoma.

Neuropilin-1 expressing melanoma cells as a model to study the aggressiveness of metastatic melanoma.

On the Horizon: Targeting Next-Generation Immune Checkpoints for Cancer Treatment

PARP Inhibitors in Cancer Therapy: Magic Bullets but Moving Targets

PARP-1 inhibition to treat cancer, ischemia, inflammation

PARP-1 modulates amyloid beta peptide-induced neuronal damage

PDIA3 Expression in Glioblastoma Modulates Macrophage/Microglia Pro-Tumor Activation

Pharmacological inhibition of poly(ADP-ribose) polymerase activity down-regulates the expression of syndecan-4 and Id-1 in endothelial cells.

Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide

Placenta growth factor and neuropilin-1 collaborate in promoting melanoma aggressiveness.

Platelet-derived growth factor C and calpain-3 are modulators of human melanoma cell invasiveness.

Poly(ADP-ribose) glycohydrolase inhibitor as chemosensitiser of malignant melanoma for temozolomide

Poly(ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis

Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells.

Poly(ADP-ribose) polymerase inhibitor olaparib hampers placental growth factor-driven activation of myelomonocytic cells.

Poly(ADP-ribose) polymerase signaling of topoisomerase 1-dependent DNA damage in carcinoma cells.

Potential clinical applications of poly(ADP-ribose) polymerase (PARP) inhibitors.

Primary cultures of microglial cells for testing toxicity of anticancer drugs.

Recent approaches to improve the antitumor efficacy of temozolomide.

Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition

Role of BRCA Mutations in Cancer Treatment with Poly(ADP-ribose) Polymerase (PARP) Inhibitors

Role of VEGFR-1 in melanoma acquired resistance to the BRAF inhibitor vemurafenib

Role of the mismatch repair system and p53 in the clastogenicity and cytotoxicity induced by bleomycin.

Targeting ADP-ribosylation by PARP inhibitors in acute myeloid leukaemia and related disorders

Targeting Tumor-Associated Macrophages to Increase the Efficacy of Immune Checkpoint Inhibitors: A Glimpse into Novel Therapeutic Approaches for Metastatic Melanoma

Telomerase as a potential anticancer target: growth inhibition and genomic instability.

The Anti-Vascular Endothelial Growth Factor Receptor-1 Monoclonal Antibody D16F7 Inhibits Glioma Growth and Angiogenesis In Vivo.

The anti-vascular endothelial growth factor receptor-1 monoclonal antibody D16F7 inhibits invasiveness of human glioblastoma and glioblastoma stem cells

The glutathione transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma.

The poly(ADP-ribose) polymerase inhibitor olaparib induces up-regulation of death receptors in primary acute myeloid leukemia blasts by NF-κB activation

Therapeutic implication of vascular endothelial growth factor receptor-1 (VEGFR-1) targeting in cancer cells and tumor microenvironment by competitive and non-competitive inhibitors

Treatment of peripheral blood with staurosporine increases detection of circulating carcinoembryonic antigen positive tumor cells.

Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome